On the prospects for the use of undenatured type II collagen in the treatment of osteoarthritis and other joint diseases by O. A. Gromova, I. Yu. Torshin, A. M. Lila, O. A. Shavlovskaya

“…Interacting with discoidin receptors, UC-II accelerates the reconstruction of cartilage connective tissue and inhibits the pro-inflammatory effects of endogenous collagens. Experimental and clinical studies confirm the effectiveness of the use of standardized substances UC-II for acceleration of cartilage regeneration and reduce pain in OA and subclinical joint dysfunction.…”
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Left ventricular hypertrophy: prognostic value, pathogenesis, possible remodeling: focusing on angiotensin receptor antagonists by M. D. Smirnova, F. T. Ageev

“…New data on hypertrophic cardiomyopathy pathogenesis point to possible ARA effectiveness in this disease as well.…”
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Pathological findings in semen analysis from COVID-19 survivors and the impact of various SARS-COV-2 vaccines on spermatogenesis by Kh. S. Ibishev, J. O. Prokop

“…This infection causes dysfunction and a negative effect on many organs and systems, including reproductive organs, which is reflected in abnormal semen parameters. …”
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A Putative Prohibitin-Calcium Nexus in β-Cell Mitochondria and Diabetes by Gaurav Verma, Aparna Dixit, Craig S. Nunemaker

“…The role of mitochondria in apoptosis is well known; however, the mechanisms linking mitochondria to the proapoptotic effects of proinflammatory cytokines, hyperglycemia, and glucolipotoxicity are not completely understood. …”
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Involvement of adenosine A1 receptor in electroacupuncture-mediated inhibition of astrocyte activation during neuropathic pain by Mingxiao Zhang, Qinxue Dai, Dongdong Liang, Dan Li, Sijia Chen, Shuangdong Chen, Kunyuan Han, Luping Huang, Junlu Wang

“…ABSTRACT Neuropathic pain is a chronic pain condition caused by damage or dysfunction of the central or peripheral nervous system. …”
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The role of probiotics in the correction of the gastrointestinal disorders in children by D. A. Khavkina, P. V. Chukhliaev, T. A. Ruzhentsova

“…The article presents a review of studies devoted to the study of the effectiveness and safety of probiotics in the complex therapy of gastrointestinal disorders in children of various ages. …”
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Role of the fibroblast growth factor type 23 in progression of complications and imbalance of calcium-phosphoric metabolism with patients suffering chronic kidney disease by A. M. Yesayan, A. N. Nimgirova, I. G. Kayukov, A. A. Yakovenko

“…The review discusses the role of fibroblast growth factor type 23 (FGF-23) in progression of renal dysfunction and its cardiovascular effects, calcium-phosphorus metabolism in patients with chronic kidney disease. …”
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Correction of the functional condition of the bile excretory system in pathogenetic management of polymorbid patients with atherosclerosis by I. A. Gorbacheva, Ju. A. Sycheva, I. V. Kyrdyumov, L. P. Egorova, O. V. Makhiaylova

“…Complex phytotherapy (phytocomplex «Hepar») with its hepatoprotective and choleratic effects was prescribed for 33 patients with atherosclerosis and hepatobiliary dysfunction (in addition to dietotherapy and choleratics). …”
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Kidney Toxicity of Drugs for the Heart: An Updated Perspective by Carlo Caiati, Roberto Arrigoni, Alessandro Stanca, Mario Erminio Lepera

“…However, some of these drugs can also cause adverse effects on the kidney, leading to acute or chronic renal dysfunction, electrolyte imbalances, and increased mortality. …”
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Angiotensin II, Aldosterone, and Anti-Inflammatory Lymphocytes: Interplay and Therapeutic Opportunities by Daniel Arthur B. Kasal, Ernesto L. Schiffrin

“…Both angiotensin II and aldosterone are involved in these systemic effects, activating innate and adaptive immune responses. …”
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Pulse pressure and cognitive impairment by O. D. Ostroumova, A. I. Kochetkov, T. M. Ostroumova

“…Due to the important role of increased PP in CI, an important aspect of antihypertensives’ effects is their impact on PP and the ability to reduce it. …”
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A narrative review of environmental noise and cardiovascular health: From molecular mechanisms to public health impact by Rahul Garg

“…The disruption of sleep architecture emerges as a central mechanism linking environmental noise to cardiovascular dysfunction. Vulnerability to these effects varies across populations, influenced by genetic, demographic, and preexisting health factors. …”
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Opioids worsen postoperative sleep: a narrative review by Siying Huang, Linlin Zhang, Yue Tian

“…This systematic review investigates the detrimental effects of opioids on postoperative sleep and explores the underlying mechanisms responsible for sleep disorders. …”
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Can microsaccade rate predict drug response? by Tom Stafford, Paul G. Overton, Elliot Hampsey

“…Sensitivity analysis suggests that the pre/post caffeine effect size is robust to choice of parameters used to identify microsaccades. …”
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Relationship between metabolic control and neurocognitive functions in children diagnosed with type I diabetes mellitus before and after 5 years of age by Ozlem Tolu-Kendir, Nurcihan Kiriş, Fatih Temiz, Fatih Gürbüz, Neslihan Onenli-Mungan, Ali Kemal Topaloğlu, Bilgin Yüksel

“… We aimed to investigate the effects of age onset of diabetes, glycemic control and frequency of hypoglycemia on neurocognitive functions in type I diabetic children. …”
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Supramolecular complex sacubitril/valsartan - the first representative of a new class of drugs for the treatment of chronic heart failure by T. V. Ashcheulova, K. M. Kompaniiets, N. M. Herasimchuk

“…Conclusions. The main positive effects of sacubitril and valsartan in patients with сhronic heart failure are associated with an increase in the amount of the natriuretic peptide and the simultaneous suppression by valsartan of the negative effects of angiotensin II. …”
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New coronavirus disease 2019 (COVID-19): Is there an impact on male reproductive health by Kh. S. Ibishev, J. O. Prokop

“…In the last three years of our time around the world, including Russia, the number of people who have become ill with a new viral infection (COVID-19) caused by the new coronavirus (SARS-CoV-2), which causes dysfunction and has a negative effect on many organs and organs, body systems.The overview of recent publications is devoted to the study of the effect of SARS-CoV-2 on the reproductive health of men. …”
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P70 | TRICHOSANTHIN TARGETS WNT/NF-KB PATHWAYS TO ATTENUATE PSORIATIC INFLAMMATION AND KERATINOCYTE HYPERPROLIFERATION

“…This was the first study to investigate the therapeutic effects of TCS topical application in the treatment of psoriasis. …”
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Renal denervation in secondary arterial hypertension therapy: clinical case by A. Yu. Orekhov, L. K. Karazhanova, A. A. Chinibaeva, A. B. Zhaksebergenova

“…This method requires a separate controlled study with individuals with renal dysfunction, including renovascular origin.…”
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Masked arterial hypertension: prevalence, pathophysiological determinants and clinical significance by В. I. Geltser, V. N. Kotelnikov, О. О. Vetrova, R. S. Karpov

“…A defined value has latent dysfunction of the mechanisms that provide circulatory homeostasis, the detection of which is possible by the hemodynamic response to psycho-emotional, hypoxic, hypocapnic, orthostatic effects. …”
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