Spontaneous Acquired Diaphragmatic Hernia: Case Series and Review of Literature by Yeshwant Lamture, Siddharth P. Dubhashi, Deepali Shetty

“…CDH usually leads to lung hypoplasia associated with pulmonary hypertension and immaturity, as well as cardiac dysfunction. In ADH, pathophysiology is secondary to herniation and its pressure effects. …”
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Mouse models of Anti-Aβ immunotherapies by Philip Pikus, R. Scott Turner, G. William Rebeck

“…Nonetheless, the combination of modest efficacy and significant rates of an adverse side effect (amyloid related imaging abnormalities, ARIA), has prompted reverse translational research in these same mouse models to better understand the mechanism of the therapies. …”
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Design and Motion Control of a Novel Weak-coupling Parallel Hip-joint Rehabilitation Mechanism by Xing Jiyuan, Xu Jilong, Liu Fucai

“…Aiming at the people with hip joint dysfunction, a novel weak-coupling parallel hip-joint rehabilitation mechanism is proposed. …”
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The role of the thymus in allogeneic haematopoietic stem cell transplantation by W Krenger, GA Holländer

“…Even though cytoreductive conditioning regimens vary in intensity, all clinically used protocols invariably cause side effects that compromise transiently or long-term the response of the natural and the adaptive immune systems. …”
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The role and research progress of serine metabolism in tumor cells by Hanning Lyu, Shuchang Bao, Lingyun Cai, Mengke Wang, Yuxin Liu, Yang Sun, Xiaoyang Hu

“…Restricting dietary serine intake or reducing the expression of serine synthetic enzymes can effectively slow tumor growth and extend patient survival. …”
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Mechanisms of hematogenous tumor metastasis. by V. I. Desyaterik, Y. S. Shevchenko

“…Thus, cancer cells spread to new tissues and, ultimately, cause organ dysfunction and death. Understanding the molecular mechanisms involved in the process of metastasis may help to effectively and purposefully prevent and treat cancer metastasis. …”
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Exercise and the Aging Endothelium by Saeid Golbidi, Ismail Laher

“…Regular physical activity, known to have a favorable effect on cardiovascular health, can also improve the function of the ageing endothelium by modulating oxidative stress and inflammatory processes, as we discuss in this paper.…”
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Mechanisms of hematogenous tumor metastasis. by V. I. Desyaterik, Y. S. Shevchenko

“…Thus, cancer cells spread to new tissues and, ultimately, cause organ dysfunction and death. Understanding the molecular mechanisms involved in the process of metastasis may help to effectively and purposefully prevent and treat cancer metastasis. …”
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trt-1 is the Caenorhabditis elegans catalytic subunit of telomerase. by Bettina Meier, Iuval Clejan, Yan Liu, Mia Lowden, Anton Gartner, Jonathan Hodgkin, Shawn Ahmed

“…These findings illustrate effects of telomere dysfunction in C. elegans mutants lacking the catalytic subunit of telomerase, trt-1.…”
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Problems in treating patients with high-risk arterial hypertension: focussing on diastolic heart failure by O. M. Drapkina

“…An increase in E/Em up to 8—15 is a sign of diastolic dysfunction. Despite substantial advances in the treatment of CHF with decreased ejection fraction, currently, there are no medications for the treatment of DCHF with effectiveness demonstrated in largescale randomised clinical trials. …”
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The Origin of Abnormal Beta Oscillations in the Parkinsonian Corticobasal Ganglia Circuits by Atefeh Asadi, Mojtaba Madadi Asl, Abdol-Hossein Vahabie, Alireza Valizadeh

“…This may provide further insights into the complex relationship between abnormal beta oscillations and motor dysfunction in PD, which is crucial for potential target-specific therapeutic interventions in PD patients.…”
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Sympathetic nerve block as an add-on therapy for intervention and prevention of cerebral vasospasm after subarachnoid hemorrhage by Zhaoquan Wang, Jianqiang Li

“…Stellate ganglion block (SGB) has been reported to have a protective effect in patients at risk for vasospasm after SAH due to reduced sympathetic activity. …”
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Dimensional Synthesis Design of a Walking Aided Training Robot by Qin Tao

“…In order to help patients with lower extremity dysfunction complete walking rehabilitation training,a plantar-driven walking aided training robot mechanism is designed. …”
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Clinical correlates of perivascular adipose tissue in coronary artery disease and obesity by Sunil Upadhaya, Amitabh C. Pandey, Jose Wiley, Thierry H. Le Jemtel

“…Finally, perivascular adipose tissue accumulation may mediate obesity-associated regional subclinical left ventricular dysfunction in the absence of coronary artery disease.…”
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Dual‐Responsive Multi‐Functional Silica Nanoparticles With Repaired Mitochondrial Functions for Efficient Alleviation of Spinal Cord Injury by Guibin Gao, Juanjuan Li, Yanming Ma, Min Xie, Jianxian Luo, Ke Wang, Cheng Peng, Hua Yang, Tianjun Chen, Guowei Zhang, Jiang Ouyang, Hongsheng Lin, Zhisheng Ji

“…Importantly, Se@NADH suppressed glial scar formation and promoted neuronal generation as well as stretching of long axons throughout the glial scar, thereby improving actual restoration of locomotor functions in mice with SCI and exerting ascendant therapeutic effects. Targeting of mitochondrial dysfunction is a potential approach for SCI treatment and may be applied to other central nervous system diseases.…”
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Olive oil protects against cardiac hypertrophy in D-galactose induced aging rats by Siamak Shahidi, Khadijeh Ramezani-Aliakbari, Abdolrahman Sarihi, Ali Heshmati, Elham Shiri, Shiva Nosrati, Sayedpayam Hashemi, Mitra Bahrami, Fatemeh Ramezani-Aliakbari

“…In the present study, we evaluated the protective effects of OLO against aging-related cardiac dysfunction. …”
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Enzyme-independent functions of HDAC3 in the adult heart by Sichong Qian, Chen Zhang, Wenbo Li, Shiyang Song, Guanqiao Lin, Zixiu Cheng, Wenjun Zhou, Huiqi Yin, Yueli Wang, Haiyang Li, Ying H. Shen, Zheng Sun

“…The cardioprotective effects of histone deacetylase (HDAC) inhibitors (HDIs) are at odds with the deleterious effects of HDAC depletion. …”
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2-Hydroxyisobutyric acid targeted binding to MT-ND3 boosts mitochondrial respiratory chain homeostasis in hippocampus to rescue diabetic cognitive impairment by Minzhen Xie, Siqi Gu, Yan Liu, Haolin Yang, Yuqi Wang, Wei Yin, Yang Hong, Wanying Lu, Chengbing He, Lin Li, Limin Zhao, Jianjia Zhang, Heng Liu, Tian Lan, Shuijie Li, Qi Wang

“…Furthermore, a combined medication plant agonist of 2-HIBA can enhance the expression of MT-ND3, thereby improving cognitive dysfunction in mice. Conclusion: MT-ND3 is a crucial target for improving diabetic cognitive dysfunction, and 2-HIBA can directly bind to the MT-ND3 protein to alleviate the functional impairment of the mitochondrial respiratory chain in mice to treat DCI.…”
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Rational Pharmacological Prophylaxis of Gestation Process Complications in Pregnant Women with Varicose Disease by Markin L., Shatylovytch K.

“…Aim. To evaluate the effectiveness of the treatment of varicose veins of the lower extremities and prevention of its gestational complications using venotonic drug Normoven. …”
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STAT1β modulates the tumor immune microenvironment to improve prognosis in ovarian cancer: a comprehensive study of transcriptional and protein expression differences by Ning Lan, Xintong Li, Yifan Qiao, Siyi Zhang, Min Chen, Xiaofeng Yang, Yuliang Zou, Juan Ren, Meili Pei

“…Clinical prognostic significance was analyzed using Cox proportional hazards regression models, complemented by multi-omics approaches including functional enrichment analysis, Tumor immune dysfunction and exclusion (TIDE) immune signature evaluation, and mediation effect models. …”
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