Suggested Topics within your search.
Suggested Topics within your search.
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5281
Identification of immune-related biomarkers linked to systemic lupus erythematosus and dilated cardiomyopathy through integrated bioinformatics analysis and multiple machine learni...
Published 2025-07-01“…The diagnostic performance and effectiveness of the nomogram were evaluated using external datasets and qPCR. …”
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5282
HCV-Related Nervous System Disorders
Published 2012-01-01“…Alternative mechanisms include possible extrahepatic replication of HCV in neural tissues and the effects of circulating inflammatory cytokines and chemokines.…”
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5283
Sarcoidosis Phenotyping: Analysis of Current Approaches (Review)
Published 2024-07-01“…It presents phenotypes based on such parameters as organ damage, respiratory dysfunction, laboratory and genetic data, and treatment effects. …”
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5284
The role of urea in pathological conditions
Published 2025-06-01“…Modern research shows the significant role of the urea and its products in the development of a number of diseases. Its pathological effects are based on dysfunction of the urea cycle enzymes of congenital or acquired nature, realized through the activation of oxidative stress, apoptosis, carbamylation, hormonal dysregulation. …”
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5285
Research progress on fermentation of kefir and its application in disease prevention and adjuvant therapy
Published 2025-04-01“…In this paper, the fermentation strains and methods of milk kefir (MK) and water kefir (WK) were introduced, and their effects on the prevention and adjuvant therapy of intestinal dysfunction, liver protection and metabolic syndrome were summarized, providing theoretical basis for the discovery of probiotic strains and the research and development of functional fermented foods.…”
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5286
The Role of Uridine Adenosine Tetraphosphate in the Vascular System
Published 2011-01-01“…The endothelium plays a pivotal role in vascular homeostasis, and endothelial dysfunction is a major feature of cardiovascular diseases, such as arterial hypertension, atherosclerosis, and diabetes. …”
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5287
Prevalence of Menstrual Irregularities in Psychiatric Patients and Its Impact on Treatment Adherence: A Cross-Sectional Study
Published 2025-06-01“…Antipsychotic medications, especially typical antipsychotics, are known to impact menstrual cycles through their effects on dopamine pathways, leading to hyperprolactinemia and subsequent menstrual dysfunction. …”
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5288
Reproductive disorders in male patients with epilepsy
Published 2016-08-01“…Issues reviewed include the aetiology of these dysfunctions (most probably due to a variety of causes), epilepsy as such, as well as drugs used for its treatment; these issues are closely related to each other and have a considerable effect on the manifestations of this condition. …”
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5289
Sacral Neuromodulation: Foray into Chronic Pelvic Pain in End Stage Endometriosis
Published 2017-01-01“…As a pilot treatment, we tested the effect of sacral neuromodulation (SNM) for four endometriosis patients suffering chronic pelvic pain and pelvic organ dysfunction after radical surgical treatment. …”
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5290
Optimizing Care for Ketamine Use Disorder: An Interdisciplinary Treatment Model
Published 2025-06-01“…Ketamine use disorder (KUD) is a disorder of regulation arising from repeated or continuous use of ketamine for at least three months. The systemic effects can include urinary, sexual, hepatic and cardiovascular dysfunction, memory impairment and mental illness. …”
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5291
A fatal case of disseminated intravascular coagulation and multiple systemic complications following multiple wasp stings
Published 2025-08-01“… Disseminated intravascular coagulation (DIC) is a rare but severe complication of wasp envenoming, caused by systemic toxic effects. We report a case of a 50-year-old Sri Lankan man who sustained over 35 wasp stings, presenting with localised pain and swelling, along with systemic complications including DIC, rhabdomyolysis, mild acute kidney injury and liver dysfunction, notably without anaphylactic shock or bleeding manifestations. …”
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5292
Electronic Cigarette and Atherosclerosis: A Comprehensive Literature Review of Latest Evidences
Published 2022-01-01“…The use of electronic cigarettes has increased significantly over the years. However, harmful effects of electronic cigarettes are still not firm. …”
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5293
ENDOCRINE DISFUNCTION IN WOMEN WITH PRE-ECLAMPSIA AND ALIMENTARY OBESITY
Published 2017-06-01“…The increasing level of leptin has a direct damaging effect on the tubular system of the kidneys.Conclusions. …”
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5294
Systematic in vivo analysis of the intrinsic determinants of amyloid Beta pathogenicity.
Published 2007-10-01“…Here we demonstrate, using rational mutagenesis of the Abeta42 peptide based on such computational predictions of aggregation propensity, the existence of a strong correlation between the propensity of Abeta42 to form protofibrils and its effect on neuronal dysfunction and degeneration in a Drosophila model of Alzheimer disease. …”
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5295
Alterations of Blood-Brain Barrier and Associated Factors in Acute Liver Failure
Published 2013-01-01“…This paper reviews the role of the paracellular tight junction in the increased selective BBB permeability that leads to brain edema in ALF and furthermore explores the effect of systemic inflammatory cytokines on the tight junction dysfunction.…”
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5296
Placental chorioangiomatosis: a case report and literature review
Published 2025-07-01“…Therefore, patients cannot be effectively treated, and pregnancy outcomes are often poor. …”
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5297
Undiagnosed Schizencephaly Presenting as Breakthrough Seizures
Published 2024-08-01“…Computed tomography and magnetic resonance imaging obtained in the emergency department was significant for large right frontoparietal open-lip schizencephaly with mass effect, a rare congenital neurologic disorder previously undiagnosed in this patient with intractable epilepsy. …”
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5298
The Russian anesthesiology and resuscitation in 2019–2020
Published 2020-05-01“…It is noted that a change in the conceptual understanding of renal dysfunction results in re-consideration of principles of management of critically ill patients with special emphasis on factors that can cause (aggravate) kidney injury. …”
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5299
PLATELET-RICH PLASMA IN ANTI-AGING AND AESTHETIC MEDICINE
Published 2024-12-01“…Skin aging is a multifactorial process influenced by intrinsic and extrinsic factors, leading to structural and functional deterioration, including wrinkles, laxity, pigmentation, and barrier dysfunction. Platelet-Rich Plasma (PRP) has emerged as a novel regenerative therapy in anti-aging and aesthetic medicine due to its ability to stimulate collagen production, tissue repair, and neo-angiogenesis through autologous growth factors. …”
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5300
BRWSP: Predicting circRNA-Disease Associations Based on Biased Random Walk to Search Paths on a Multiple Heterogeneous Network
Published 2019-01-01“…The circular RNAs (circRNAs) have significant effects on a variety of biological processes, the dysfunction of which is closely related to the emergence and development of diseases. …”
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