Living donor liver transplantation for a patient with acute liver failure following thyroid storm: a case report by Kantoku Nagakawa, Akihiko Soyama, Takanobu Hara, Hajime Matsushima, Hajime Imamura, Takayuki Tanaka, Michi Morita, Sakaya Kuba, Tomohiko Adachi, Masaaki Hidaka, Hisamitsu Miyaaki, Satoru Akazawa, Ichiro Horie, Motohiro Sekino, Tetsuya Hara, Shinji Okano, Kazuhiko Nakao, Susumu Eguchi

“…Abstract Background Thyroid storm can be complicated by liver dysfunction, which may occasionally progress to acute liver failure. …”
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A epidemiological trend of chronic kidney disease due to hypertension among adolescents and young adults: global burden and future 2035 projections by Tao Wang, Rui Pan, Cong Li, Ying Qin, Chao Song

“…Globally, dietary risks kidney dysfunction, high systolic blood pressure, were key risk factors for CKD due to hypertension-associated mortality in 2021. …”
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Unveiling the molecular mechanisms of Danggui-Shaoyao-San against Alzheimer’s disease in APP/PS1 mice via integrating proteomic and metabolomic approaches by Qihui Wu, Wei Wang, Zhuangzi Huang, Xianghao Lin, Maozhong Yao, Chuipu Cai, Guohu Weng, Yong Gu, Hongying Li, Jinman Liu, Jiansong Fang, Weirong Li

“…However, it remains unclear whether DSS exerts therapeutic effects on AD through EM regulation. Methods In this study, we conducted behavioural tests, Nissl staining, haematoxylin and eosin staining, and thioflavin S staining, in APP/PS1 mice to assess the pharmacodynamic effect of DSS on AD. …”
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Ultrasound-guided percutaneous thermal ablation of parotid tumors: experience from two-centers by Min Zhuang, Yucheng Lin, Songsong Wu, Man Lu, Zirui Jiang, Ting Wei, Lu Wang, Shishi Wang, Jie Zou, Yi He

“…The incidence of facial nerve dysfunction was 8.70%.Conclusion: Ultrasound-guided percutaneous TA is an effective and safe treatment option for patients with benign parotid tumors.…”
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Ventricular volume adjustment of brain regions depicts brain changes associated with HIV infection and aging better than intracranial volume adjustment by Benedictor Alexander Nguchu, Benedictor Alexander Nguchu, Jing Zhao, Jiajun Fan, Yifei Han, Yu Lu, Han Jin, Yanming Wang, Hongjun Li, Peter Shaw

“…The analyses of LV-adjusted metrics also show that atrophic patterns observed in the hippocampus, thalamus and pallidum were strongly correlated with HAND(especially dysfunction in executive function) and clinical markers (i.e., CD4/CD8 ratio).ConclusionWe conclude that models that control for individual variability in intracranial and ventricular volumes have the potential to minimize discrepancies and variations in structural reports of HIV, improving the diagnostic power of identified patterns and fostering greater consistency across research studies. …”
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Transoral approach to the craniovertebral junction Acesso transoral para a junção craniocervical by José Alberto Landeiro, Sávio Boechat, Daniel de Holanda Christoph, Mariângela Barbi Gonçalves, Igor de Castro, Mario Alberto Lapenta, Carlos Henrique Ribeiro

“…We analyzed the clinical effects of odontoidectomy after treating 38 patients with basilar invagination. …”
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Trans Fats in Spanish Pastries and Their Influence on Mesenchymal Stem Cell Behavior In Vitro and Related Health Risks by Camilo Zamora-Ledezma, José Manuel Martínez-Hernandez, Jeevithan Elango, Judit Garcia-Garrido, Juana María Morillas-Ruiz, Eliana Díaz-Cruces, Pablo Javier Miró-Colmenárez, Ezequiel Zamora-Ledezma

“…Trans fats are linked to numerous chronic diseases and cellular dysfunction; however, Spain has not implemented effective regulatory measures to restrict their presence in food products. …”
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Eliminating Heavy Metals from Water with Nano-Sheet Minerals as Adsorbents by Shaoxian Song

“…Mercury is a horrible neurotoxin that may result in damages to the central nervous system, dysfunction of pulmonary and kidney, chest and dyspnea. …”
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Plasma cytomegalovirus DNA load predicts outcomes in liver transplant recipients by Hao‐Chien Hung, Po‐Jung Hsu, Jin‐Chiao Lee, Yu‐Chao Wang, Chih‐Hsien Cheng, Tsung‐Han Wu, Ting‐Jung Wu, Hong‐Shiue Chou, Kun‐Ming Chan, Wei‐Chen Lee, Chen‐Fang Lee

“…Conclusion Our findings support evidence that qPCR is effective in detecting CMV infection provides an objective perspective in predicting posttransplant outcomes. …”
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Resveratrol targeting MDM2/P53/PUMA axis to inhibit colonocyte apoptosis in DSS-induced ulcerative colitis mice by Rui Tang, Rui Tang, Ling Jiang, Quan Ji, Pengyuan Kang, Yuan Liu, Pengyu Miao, Xiaofan Xu, Mingxi Tang, Mingxi Tang, Mingxi Tang

“…Nutlin-3a, an MDM2 inhibitor, reversed the anti-apoptotic effects of Resveratrol. Overexpression of MDM2 in the colon protected against DSS-induced damage.ConclusionResveratrol is an effective treatment for DSS-induced UC, primarily by inhibiting excessive apoptosis in colonocytes through the MDM2/P53/PUMA axis. …”
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Rescue of common and rare exon 2 skipping variants of the GAA gene using modified U1 snRNA by Paolo Peruzzo, Natascha Bergamin, Martina Bon, Sara Cappelli, Alessandra Longo, Elisa Goina, Cristiana Stuani, Emanuele Buratti, Andrea Dardis

“…As a result, undigested glycogen accumulates within lysosomes causing their dysfunction. From a clinical point of view, the disease can be classified in infantile-onset (IO) and late-onset (LO) forms. …”
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Advances in Development of PM2.5-Exposed Animal Models and Their Application in Reproductive Toxicity Research by TIAN Fang, PAN Bin, SHI Jiayi, XU Yanyi, LI Weihua

“…Long-term studies are also necessary to assess the effects of PM2.5 exposure on reproductive health and transgenerational effects, to predict potential long-term risks for humans. …”
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Patients with uHCC and Child-Pugh B8/9 also benefit from a combination of antiangiogenic agents and PD-1 inhibitors: a multicenter real-world study by Xiaoyan Ding, Xue Yin, Linlin Zheng, Lin Zhou, Junke Hu, Wei Sun, Lei Sun, Yanjun Shen, Ying Teng, Yawen Xu, Wendong Li, Mei Liu, Jinglong Chen

“…Notably, 30.2% of patients maintained sustained radiographic responses despite advanced liver dysfunction. Interpretation: Combining TKIs with PD-1 inhibitors is an effective and well-tolerated option for HCC patients with Child-Pugh B, including those with CP8/9. …”
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Peptide CyRL-QN15 alleviates UVB-induced skin aging by promoting the repair of barrier by Zijian Kang, Saige Yin, Xiaoya Han, Xin Liu, Ying Peng, Qiuye Jia, Zhe Fu, Yuansheng Li, Yutong Wu, Zhaoxun Xiao, Zhiruo Li, Ying Wang, Mingying Luo, Xinwang Yang

“…Despite advancements in dermatological research, effective prevention and reversal of photoaging remain challenging. …”
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Baoshentongluo Formula relieves podocyte injury in diabetic kidney disease through regulating mitophagy via PINK1/Parkin signaling pathway by Yanyu Pang, Lei Tian, Yufei Liu, Yifan Guo, Jingwen Zhao, Yutong Wang, Mengdi Wang, Wenjing Zhao

“…IntroductionDiabetic kidney disease (DKD) progression is strongly associated with podocyte mitochondrial dysfunction. The clinically effective Chinese herbal Baoshentongluo formula (BSTL) has demonstrated significant proteinuria reduction in DKD patients. …”
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Complement pathway: Risk molecular pattern of cardiovascular diseases in patients with diabetic nephropathy by Liu JunFei, Qian XiaoPing, Wang TaoXia, Liu XiaoLi, Liu WeiGang, Wang LiJie, Zhang HuiFang, Han Li, Li GuiYing, Yu XiaoJuan

“…The current effective treatment of DN and CVD demands identifying and managing their risk factors. …”
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Polydatin and Nicotinamide Prevent Iron Accumulation and Lipid Peroxidation in Cellular Models of Mitochondrial Diseases by Paula Cilleros-Holgado, David Gómez-Fernández, Rocío Piñero-Pérez, José Manuel Romero-Domínguez, Diana Reche-López, Mónica Álvarez-Córdoba, Ana Romero-González, Alejandra López-Cabrera, Marta Castro De Oliveira, Andrés Rodríguez-Sacristán, Susana González-Granero, José Manuel García-Verdugo, José Antonio Sánchez-Alcázar

“…Treatment with polydatin and nicotinamide effectively corrected these alterations and reduced iron accumulation and lipid peroxidation in induced neurons. …”
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Immediate efficacy of low-intensity focused ultrasound versus planar ultrasound in patients with myofascial pain syndrome of upper trapezius: a randomized controlled clinical trial by Yongjia Chen, Yannan Sun, Xize Li, Yijun Lin, Peijue He, Qian Wang

“…Abstract Background Myofascial pain syndrome (MPS), a chronic musculoskeletal disorder characterized by myofascial trigger points (MTrPs), causes localized pain and dysfunction. The objective is to compare the immediate therapeutic effects of low-intensity focused ultrasound (LIFU) versus low-intensity planar ultrasound (LIPU) on pain and function in upper trapezius MPS. …”
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Pasteurized <i>Akkermansia muciniphila</i> Ameliorates Preeclampsia in Mice by Enhancing Gut Barrier Integrity, Improving Endothelial Function, and Modulating Gut Metabolic Dysregu... by Linyu Peng, Qinlan Yin, Xinwen Wang, Yawen Zhong, Yu Wang, Wanting Cai, Ruisi Zhou, Ying Chen, Yu Hu, Zhixing Cheng, Wenqian Jiang, Xiaojing Yue, Liping Huang

“…Preeclampsia (PE) is a serious complication of pregnancy linked to endothelial dysfunction and an imbalance in the gut microbiota. …”
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Relationship of left ventricular, elastic and muscular arteries remodeling in patients with uncontrolled arterial hypertension by S. Ya. Dotsenko, V. G. Deynega, N. Ya. Dotsenko

“…The severity and character of diastolic dysfunction, hypertrophy, types of remodeling and stiffness were assessed. …”
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