Targeting the Parkinson’s disease using sim (Rhodomyrtus tomentosa) fruit water extract by Ngo Binh Thao Nghi, Dao My Linh, Dang Thi Phuong Thao

“…Abstract Parkinson's disease (PD) is a progressive nervous system disorder characterized by dysfunction or degeneration of dopaminergic neurons in the substantia nigra leading to motor symptoms. …”
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Mitotherapy attenuates sepsis-induced brain injury in rats subjected to cecal ligation and puncture: Role of SIRT-1/PGC-1α network by Behnaz Mokhtari, Alireza Alihemmati, Soleyman Bafadam, Solmaz Boraghi, Reza Badalzadeh, Ata Mahmoodpoor

“…Objective(s): Sepsis-induced brain injury poses a critical challenge with limited therapeutic options. Mitochondrial dysfunction is a central contributor to this pathogenesis. …”
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Paediatric goal management training in patients with acquired brain injury: study protocol for a randomised controlled trial by Eva Skovlund, Ruth Elizabeth Hypher, Anne Elisabeth Brandt, Kari Risnes, Torstein Baade Rø, Stein Andersson, Torun Gangaune Finnanger, Jan Stubberud

“…Introduction Compromised integrity of the brain due to paediatric acquired brain injury (pABI) has been associated with cognitive impairment, particularly executive dysfunction, in addition to somatic and emotional symptoms and reduced everyday function. …”
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Integrated differentiated therapy of patients with relapses of rosacea taking into account heart rate variability indices and psychological status changes by A. V. Vasilenko

“…Еarly diagnosis of changes in the ANS allows to predict the course of disease and to increase the effectiveness of treatment of relapses of rosacea.…”
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Resmetirom: The First Disease-Specific Treatment for MASH by Ali Mohamed Mousa, Mervat Mahmoud, Ghaida Mubarak AlShuraiaan

“…Resmetirom, a thyroid hormone receptor-beta (THR-β) agonist, specifically targets liver function to simulate localized hyperthyroidism, effectively reducing lipid accumulation and liver fibrosis without the systemic effects commonly associated with thyroid hormone therapy. …”
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Maca: its uses in menopause by José Núñez-Troconis

“…This narrative review was conducted to assess the effects of Maca on a variety of conditions but doing emphasis on menopausal symptoms. …”
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Anesthesia Management Using Remimazolam in A Patient With Bernard‐Soulier Syndrome: A Case Report by Tomoharu Shakuo, Yusuke Ishida, Daiki Sugawara, Masato Ryo, Haruko Okazaki, Katsunori Oe

“…ABSTRACT Bernard‐Soulier syndrome (BSS) is a platelet dysfunction disorder characterized by massive thrombocytopenia and a lack of platelet aggregation. …”
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Exosome Loaded in Microneedle Patch Ameliorates Renal Ischemia–Reperfusion Injury in a Mouse Model by Samin Taghavi, Somayeh Keshtkar, Mozhgan Abedanzadeh, Mehrdad Hashemi, Reza Heidari, Samira Sadat Abolmaali, Mahintaj Dara, Mahdokht Hossein Aghdaei, Alireza Sabegh, Negar Azarpira

“…In comparison to exosome injection alone, microneedle patch-exosome treatment offers a longer and more targeted effect that improves renal IRI dysfunction and reduces tissue damage, potentially facilitating the clinical application of exosomes and improving graft survival.…”
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Myocardial infarction and pulmonary embolism in a young man during feminizing gender-affirming therapy: а case report by D. A. Grabovyi, G. R. Bikbaeva, I. A. Osadchii, A. A. Tukhbatova, D. V. Duplyakov

“…This is a consequence of an increase in serum coagulation factors and a direct effect on endothelial dysfunction, which enhances platelet aggregation. …”
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Functional indicators of peripheral arterial stiffness in solid organ recipients (literature review) by M. M. Lysenko, I. Yu. Tyunyaeva, A. O. Shevchenko

“…Increased arterial stiffness is an important preclinical indicator of cardiovascular dysfunction, arterial hypertension and target organ injury. …”
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Non-ischemic cardiomyopathy after rituximab treatment for mucous membrane pemphigoid: a case report by Jas Virk, David Notman, Vinay Thohan

“…This case emphasizes the importance of recognizing the potential cardiotoxic effects of biological agents used in autoimmune disease management and supports the consideration of cardiac surveillance in at-risk patients receiving rituximab.…”
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Cigarette Smoking and Adipose Tissue: The Emerging Role in Progression of Atherosclerosis by Zhiyan Wang, Di Wang, Yi Wang

“…Herein, this review aims to investigate the possible interplay between smoking and adipose tissue dysfunction in the development of atherosclerosis.…”
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Albumine solution and modern concepts of infusion therapy: does the story continue? by V. V. Kulabukhov, A. A. Konkin, M. D. Utev

“…Hypoalbuminemia and hypovolemia are independent risk factors for the development of multiple organ dysfunction, the main cause of death in critically ill patients. …”
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Human induced pluripotent stem cell-derived myotubes to model inclusion body myositis by Judith Cantó-Santos, Laura Valls-Roca, Ester Tobías, Francesc Josep García-García, Mariona Guitart-Mampel, Félix Andújar-Sánchez, Adrià Vilaseca-Capel, Anna Esteve-Codina, Beatriz Martín-Mur, Joan Padrosa, Emma Peruga, Irene Madrigal, Paula Segalés, Carmen García-Ruiz, José Carlos Fernández-Checa, Pedro J. Moreno-Lozano, Albert Selva O’Callaghan, Ana Sevilla, José César Milisenda, Glòria Garrabou

“…Overall, these findings support patient-derived iPSC-myotubes as a relevant model for IBM, reflecting the main muscle hallmarks, including inflammation, autophagy dysfunction and mitochondrial alterations at transcriptomic, protein and functional levels.…”
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Neural Stem Cells in the Diabetic Brain by Tomás P. Bachor, Angela M. Suburo

“…Moreover, behavioral disorders suggest that a similar dysfunction of the neurogenic niches most likely affects diabetic and prediabetic patients. …”
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Obesity, aldosterone excess, and mineralocorticoid receptor activation: Parallel or intersected circumstances? by Houry Puzantian, Raymond Townsend, Shweta Bansal

“…The consequences of aldosterone excess in obesity are presented as genomic, non‐genomic, and non‐epithelial effects. Moreover, the authors emphasize the value of interference with aldosterone pathophysiology (as with mineralocorticoid antagonists) in obesity, thus reducing the adverse clinical impact of aldosterone in myocardial infarction, heart failure, kidney dysfunction, and associated mortality.…”
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Redox Regulation of Cysteine-Dependent Enzymes in Neurodegeneration by Rodney P. Guttmann, Tamara J. Powell

“…While it is unclear whether oxidative stress is a cause or effect, protein, lipid, and DNA have all been found to be susceptible to oxidant-induced modifications that alter their function. …”
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Exploring the scope of inspiratory muscle training in difficult weaning: reflections on the multicentre RCT by Sireesha Chilakapati, Jyothi Koteswara Rao, Bharat Paliwal

“…Future research could benefit from subgroup analyses, individual response curves, and further investigation into the unexpected adverse effects observed in the low-intensity group to refine the inspiratory muscle training protocols.…”
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The Nervous System Contributes to the Tumorigenesis and Progression of Human Digestive Tract Cancer by Dayou Dai, Hao Liu

“…Homeostasis of the neuroendocrine-immune axis (NEI axis) maintains a healthy in vivo environment in humans, and dysfunction of the axis contributes to various cancers, including the digestive tract. …”
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Emulation with Organic Memristive Devices of Impairment of LTP Mechanism in Neurodegenerative Disease Pathology by Silvia Battistoni, Victor Erokhin, Salvatore Iannotta

“…We provide here evidences of the ability of emulating the dysfunctional synaptic behavior typical of the AD pathology with organic memristive devices considering the effect of the disease not only on a single synapse but also in the case of a neural network, composed by numerous synapses.…”
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