Organizational Characteristics Associated With ICU Liberation (ABCDEF) Bundle Implementation by Adult ICUs in Michigan by Juliana Barr, MD, FCCM, Amir A. Ghaferi, MD, MS, FACS, FASMBS, Deena Kelly Costa, PhD, RN, Haley K. Hedlin, PhD, Victoria Y. Ding, MS, Corine Ross, , MHA, Brenda T. Pun, DNP, RN, Sam R. Watson, MSA, MT(ASCP), CPPS, Steven M. Asch, MD, MPH

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Predicting sleep quality among college students during COVID-19 lockdown using a LASSO-based neural network model by Lufeng Chen, Qingquan Chen, Zhimin Huang, Ling Yao, Jiajing Zhuang, Haibin Lu, Yifu Zeng, Jimin Fan, Ailing Song, Yixiang Zhang

“…Sleep quality, sleep latency, sleep efficiency, diurnal dysfunction, and PSQI score were all higher than the national norm (P < 0.05). …”
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Comparing modified light bulb with multiple drilling methods in treating non-traumatic femoral head osteonecrosis: A cohort study by Ali Parsa, Hamid Dolatabadi, Saeid Esmaeilian, Seyed Ali Moshtaghioon, Neda Mirzaei, Omid Shahpari, Elham Rahmanipour, Mohammad Ghorbani

“…Conclusions: Both MD and MLB techniques are effective for treating non-traumatic ONFH in the pre-collapse stage, with the MLB technique showing superior outcomes in terms of pain relief and functional improvement. …”
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Arecoline alleviates autism spectrum disorder-like behaviors and cognition disorders in a valproic acid mouse model by activating the AMPK/CREB/BDNF signaling pathway by Chunyan Wen, Zhizhong Xu, Fengling Cao, Qianfa Yuan, Weichao Su, Zhiyuan Huang

“…Studies in humans have revealed that the pathogenesis of autism spectrum disorder (ASD) is linked to white matter abnormalities involving hypomyelination and oligodendroglia dysfunction; however, effective treatments remain limited. …”
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Primary Prevention Strategy for Non-Communicable Diseases (NCDs) and Their Risk Factors: The Role of Intestinal Microbiota by Itzel Ivonn López-Tenorio, Óscar Rodrigo Aguilar-Villegas, Yoshua Espinoza-Palacios, Lorena Segura-Real, Berenice Peña-Aparicio, Amedeo Amedei, María Magdalena Aguirre-García

“…These conditions have numerous health consequences and significantly impact patients’ lifestyles. Effective long-term treatment is essential since NCDs are irreversible. …”
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C60 fullerene promotes recovering rat musculus gastrocnemius contracting activity after neurogenic atrophy by Дмитро Ноздренко, Максим Ангелов, Ігор Варенюк, Микола Дзержинський, Катерина Богуцька, Вадим Теплюк, Ігор Неділько, Володимир Берест, Юрій Прилуцький

“…Therefore, the search for effective therapeutic means for its acceleration is an extremely urgent task in modern biomedicine. …”
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Two-Year Mediterranean Diet Intervention Improves Hepatic Health in MASLD Patients by Margalida Monserrat-Mesquida, Cristina Bouzas, Silvia García, David Mateos, Miguel Casares, Lucía Ugarriza, Cristina Gómez, Antoni Sureda, Josep A. Tur

“…<b><i>Background:</i></b> Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) is one of the leading causes of chronic liver disease, affecting 30% of the global adult population and continuing to rise. …”
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Comprehensive biomarker assessment for predicting severe acute kidney injury and need of kidney replacement therapy in liver transplantation patients by Camila Lima, Gillene Santos Ferreira, Maria de Fátima Fernandes Vattimo, Luciana Bertocco de Paiva Haddad, Luiz Marcelo Malbouisson, Luiz Augusto Carneiro D’Albuquerque, Alexandre Toledo Maciel, Etienne Macedo

“…Background Renal dysfunction is a common complication following liver transplantation (LT). …”
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Laser technologies in surgery for benign prostate hyperplasia by S. A. Rakhimov, I.  V. Feofilov, I. A. Arbuzov

“…One of the modern surgical methods for treating BPH is the use of laser technologies.Objective. To compare the effectiveness and safety of laser technologies using the example of the use of diode and thulium lasers in BPH surgery.Materials &amp; methods. …”
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Hydroxysafflor Yellow A modulation of metabolite networks and inhibition of JAK2/STAT1 pathway in sepsis by Bingbing Pan, Fengting Chen, Siyan Shen, Yu Jiang, Ying Yang, Jia Wang, Yanjuan Liu, Lai Wei, Jitong Liu, Gaoyin Kong, Xuan He, Bing Guo

“…Abstract Sepsis, a severe infectious disease causing multiple organ dysfunction, requires further exploration of its pathomechanisms and therapeutic options. …”
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Successful long-term survival following lipiodol chemoembolization for hepatocellular carcinoma in Alagille syndrome: A case report by Imad Akasbi, MD, Ismail Chaouche, MD, Nizar El Bouardi, MD, Amal Akammar, MD, Hajar O Chahdi, MD, Ismail Zerrari, MD, Maria Lahlali, MD, Hakima Abid, MD, Badr Alami, MD, Nada Lahmidani, MD, Meryem Boubbou, MD, Ibrahimi Sidi adil, MD, Mustapha Maaroufi, MD, MY Youssef Alaoui Lamrani, MD

“…Alagille syndrome is a rare genetic disorder causing multisystem complications, including biliary abnormalities, chronic liver disease, and rarely, hepatocellular carcinoma (HCC), which is difficult to manage due to liver dysfunction and vascular abnormalities. We report a 29-year-old female, diagnosed with Alagille syndrome in infancy, who developed infiltrative HCC at age 20 and underwent lipiodol-based transarterial chemoembolization (TACE) in 2015, with a second session in 2016 for recurrence. …”
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Targeting HVEM-GPT2 axis: a novel approach to T cell activation and metabolic reprogramming in non-small cell lung cancer therapy by Yuanshan Yao, Chunji Chen, Bin Li, Wen Gao

“…Abstract Background The modulation of tumor microenvironments through immune checkpoint pathways is pivotal for the development of effective cancer immunotherapies. This study aims to explore the role of HVEM in non-small cell lung cancer (NSCLC) microenvironment. …”
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ATYPICAL HEMOLYTIC UREMIC SYNDROME DIAGNOSIS AND TREATMENT by Atakan Turgutkaya

“…Ravulizumab is a long-acting C5 inhibitor that is considered safe and effective in both treatment-naive adult and pediatric patients and in pediatric patients who have previously received complement inhibition [4]. …”
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Metastatic Cervicomedullary Lesion in the Postpartum Period: A Case-Based Review of CNS Metastases in Pregnancy and Postpartum Period by Sarvesh Goyal, Kushagra Pandey, Arunath Kalappuraikkal, Santanu Kumar Bora, Anubhav Narwal, Deepak Gupta

“…Whole-brain radiotherapy (WBRT) and chemotherapy, while effective, are typically reserved for cases of multiple metastases or systemic disease. …”
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A CLINICAL CASE OF THE USE OF AN IMMUNOMODULATORY DRUG IN THE COMPLEX THERAPY OF SEVERE GENERALIZED PERIODONTITIS by G.М. Silenko, H.M. Sylenko

“…Destructive periodontal changes in chronic generalized periodontitis (CGP) are often irreversible and, in combination with dysfunction of the dento-alveolar apparatus and premature loss of teeth, they impair the quality of patients’ life and decrease their social adaptation. …”
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Clinical course and management challenges in Lafora disease: a narrative analysis in an Apulian cohort by Giuseppe d’Orsi, Maria Teresa Di Claudio, Antonella Liantonio, Paola Imbrici, Cosimo Damiano Altomare, Orazio Palumbo, Pietro Palumbo, Mario Benvenuto, Nicola Gambacorta, Graziano Lolli, DEFEAT-LD study group, Massimo Carella

“…Abstract Background Lafora disease (LD) is an ultra-rare, autosomal recessive neurodegenerative disorder characterized by the accumulation of Lafora bodies in the brain, leading to drug-resistant epilepsy, myoclonus, progressive dementia, and cerebellar dysfunction. This retrospective study describes the clinical course and management challenges of LD in a cohort of patients from the Apulia region of Southern Italy, where the disease prevalence appears to be higher than in other populations. …”
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Disopyramide Revisited for Treatment of Symptomatic Obstructive Hypertrophic Cardiomyopathy: Efficacy and Safety in Patients Treated for at Least 5 Years by Daniele Massera, Mark V. Sherrid, Elizabeth Adlestein, Nadia Bokhari, Isabel C. Alvarez, Woon Y. Wu, Maria C. Reuter, Martin S. Maron, Barry J. Maron, Ethan J. Rowin

“…Ventricular tachyarrhythmias and left ventricular systolic dysfunction were uncommon (n=3 and n=1) and were not attributed to disopyramide. …”
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CARDIOVASCULAR RISK FACTORS IN PATIENTS WITH OBSTRUCTIVE SLEEP APNEA SYNDROME by A. V. Markin, T. I. Martynenko, G. I. Kostyuchenko, I. Ya. Tseimakh, Ya. N. Shoikhet

“…The paper analyzes the cause-and-effect relations of obstructive sleep apnea syndrome (OSAS) and cardiovascular diseases (CVD). …”
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INTEGRATION OF BIOMARKERS INTO THE PRACTICE OF TREATING PATIENTS WITH HEART FAILURE: THE ROLE OF DETERMINING THE BLOOD LEVEL OF NATRIURETIC PEPTIDES by S. R. Gilyarevskiy, M. V. Golshmid, I. M. Kuzmina

“…The most important evidences of clinical effectiveness of using biomarkers in patients with suspected heart failure and in patients with confirmed diagnose of heart failure are reviewed. …”
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The Importance of Mitochondrial DNA in Aging and Cancer by Claus Desler, Maiken Lise Marcker, Keshav K. Singh, Lene Juel Rasmussen

“…Mitochondrial dysfunction has been implicated in premature aging, age-related diseases, and tumor initiation and progression. …”
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