Neuroimaging and biological markers of different paretic hand outcomes after stroke by Zhujun Wang, Manxu Zheng, Binke Yuan, Yingteng Zhang, Wenjun Hong, Chaozheng Tang, Wen Wu

“…Abstract Background Hand dysfunction significantly affects independence after stroke, with outcomes varying across individuals. …”
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Clinical impacts of total parenteral nutrition in hematopoietic stem cell transplantation patients with high nutritional risk by Le Yang, Di Wu, Junting Dai, Huiyi Lv, Miao Li

“…Furthermore, the TPN group experienced a shorter length of hospital stay (48.06 ± 13.90 in the control group, 42.13 ± 14.22* in the TPN group, p < 0.05) and lower rates of unexpected rehospitalization (37.1% in the control group, 21.4% in the TPN group, p < 0.05).ConclusionThis study demonstrated that effective TPN formulations improved nutritional status, ensured patient safety, and contributed to better clinical outcomes in HSCT patients at high nutritional risk. …”
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Pathophysiology and blood pressure measurements of hypertension in the elderly by Fan-Yu Chen, Chun-Wei Lee, Yu-Jen Chen, Yen-Hung Lin, Chih-Fan Yeh, Chih-Ching Lin, Hao-Min Cheng

“…In the second part of this review, we evaluate the effectiveness of blood pressure monitoring in older adults, emphasizing the importance of precise measurements. …”
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Real-World Outcomes of Allogeneic Immunosafe Plasma Rich in Growth Factors Eye Drops for Refractory Ocular Surface Diseases: A Prospective Observational Study by Rosa Alvarado-Villacorta, Jesús Merayo-Lloves, Ronald M. Sánchez-Ávila, Belén Alfonso-Bartolozzi, Carlos Lisa, Luis Fernández-Vega-Cueto, José F. Alfonso, Eduardo Anitua

“…Secondary outcomes included best-corrected visual acuity (BCVA), intraocular pressure (IOP), corneal staining, Schirmer I test, tear break-up time (BUT), conjunctival bulbar redness, and meibomian gland dysfunction (MGD). Multilevel mixed-effects models were used to account for intra-patient and inter-eye correlations. …”
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Possible causes, ways of development and stages of formation of atopic dermatitis in children by O.V. Gryn, O.M. Okhotnikova

“…Understanding and further study of this interaction is necessary for developing effective approaches to the prevention and treatment of atopic dermatitis.…”
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Screening for Heart Failure in Patients with Hypertension And/Or Diabetes Using Hand-Held Echocardiography: A Pilot Study by Zi-Xuan Yang, Yu Kang, Xue-Ke Zhong, Qiao-Wei Chen, Yi She, Yun Guo, Xiao-Jing Chen, Hua Wang, Qing Zhang

“…The diagnostic accuracy and cost-effectiveness of several pre-specified screening strategies were compared. …”
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Adeno-associated virus mediated artificial circular RNA for triggering cancer immunotherapy to treat prostate cancer by Chujin Ye, Chujin Ye, Zhiye Liu, Zhiye Liu, Qifan Xie, Qifan Xie, Yanlin Tang, Yanlin Tang, Jiayi Zeng, Jiayi Zeng, Ziwei Feng, Ziwei Feng, Jiumin Liu, Jiumin Liu, Haibiao Xie, Haibiao Xie

“…Naturally occurring circular RNAs (circRNAs) are structurally stable and have been proved to serve as highly efficient miR-sponges and protein-sponges in cancer cells.MethodsWe chemically synthesized circRNA (ScircRNA) in vitro to achieve therapeutic dysfunction by targeting specific miRNAs. RNase R and fetal bovine serum were used to evaluate the stability of ScircRNAs. …”
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Engineered anti-cancer nanomedicine for synergistic cuproptosis-immunotherapy by Jiaxin Li, Xinlong Pang, Zhongwei Xin, Liang Song, Xiangyan Liu, Xinyu Zhang, Zhe Yang

“…The combination of cuproptosis-inducing strategies with immunotherapeutic approaches presents a novel and potentially effective direction for future cancer treatment.…”
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The impact of HIV antiretroviral therapy on gut microbiota: the need for well-designed longitudinal studies by Oumar Dolo, Fousseini Coulibaly, Anou M Somboro, Djeneba B Fofana, Josue Togo, Aliou Balde, Dramane Diallo, Aminata Maiga, Bassirou Diarra, Robert L Murphy, Saidou Balam, Jane Holl, Mariam Sylla, Mamoudou Maiga, Almoustapha I Maiga

“…These changes also revealed dysfunction in microbial translocation and some immune markers, including T lymphocyte rates and the overall inflammation balance. …”
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Exploring Oxidative Stress Mechanisms of Nanoparticles Using Zebrafish (<i>Danio rerio</i>): Toxicological and Pharmaceutical Insights by Denisa Batir-Marin, Monica Boev, Oana Cioanca, Ionut-Iulian Lungu, George-Alexandru Marin, Ana Flavia Burlec, Andreea-Maria Mitran, Cornelia Mircea, Monica Hancianu

“…This redox imbalance, primarily driven by the overproduction of reactive oxygen species (ROS), plays a central role in NP-induced toxicity, leading to cellular dysfunction, inflammation, apoptosis, and genotoxicity. …”
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Pancreatic Morphology, Immunology, and the Pathogenesis of Acute Pancreatitis by Tudorel Mihoc, Silviu Constantin Latcu, Cosmin-Ciprian Secasan, Vlad Dema, Alin Adrian Cumpanas, Mircea Selaru, Catalin Alexandru Pirvu, Andrei Paul Valceanu, Flavia Zara, Cristina-Stefania Dumitru, Dorin Novacescu, Stelian Pantea

“…In acute pancreatitis, the disruption of intracellular calcium signaling leads to premature enzyme activation, triggering a cascade of events including mitochondrial dysfunction, ATP depletion, and the release of proinflammatory mediators. …”
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Open-access ultrasonic diaphragm dataset and an automatic diaphragm measurement using deep learning network by Zhifei Li, Lin Mao, Fan Jia, Shaohui Zhang, Cuiping Han, Shuiqiao Fu, Yueying Zheng, Yonghua Chu, Zuobing Chen, Daming Wang, Huilong Duan, Yinfei Zheng

“…Abstract Background The assessment of diaphragm function is crucial for effective clinical management and the prevention of complications associated with diaphragmatic dysfunction. …”
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Improved survival and neurological outcomes with lysophosphatidylcholine supplementation in severe cardiac arrest model by Muhammad Shoaib, Muhammad Shoaib, Mitsuaki Nishikimi, Rishabh C. Choudhary, Tsukasa Yagi, Kei Hayashida, Tai Yin, Blanca B. Espin, Lance B. Becker, Lance B. Becker, Lance B. Becker, Junhwan Kim, Junhwan Kim, Junhwan Kim

“…The study also compared the effects of combining multiple LPC species with individual species to better determine the most effective strategy and enhance the translational potential of LPC therapy for CA treatment. …”
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Topical administration of GLP-1 eyedrops improves retinal ganglion cell function by facilitating presynaptic GABA release in early experimental diabetes by Yu-Qi Shao, Yong-Chen Wang, Lu Wang, Hang-Ze Ruan, Yun-Feng Liu, Ti-Hui Zhang, Shi-Jun Weng, Xiong-Li Yang, Yong-Mei Zhong

“…Diabetic retinopathy is a prominent cause of blindness in adults, with early retinal ganglion cell loss contributing to visual dysfunction or blindness. In the brain, defects in γ-aminobutyric acid synaptic transmission are associated with pathophysiological and neurodegenerative disorders, whereas glucagon-like peptide-1 has demonstrated neuroprotective effects. …”
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Acupuncture for poststroke hemiplegia focusing on cerebral bilateral connections: study protocol for a randomised controlled neuroimaging trial by Yue Wang, Hua Zhang, Xiao Han, Lan Jiang, Hualei Geng, Mengxin Lu, Zhongming Du, Pei Chen, Lixin Tang, Zhongjian Tan, Yihuai Zou

“…Introduction Acupuncture is safe and effective for improving the motor function of poststroke hemiplegic patients, but there still exists a certain gap between clinical practice and understanding its neural mechanisms. …”
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Toxoplasmosis accelerates the progression of hereditary spastic paraplegia by James R. Alvin, Carlos J. Ramírez-Flores, Caitlin A. Mendina, Anjon Audhya, Laura J. Knoll, Molly M. Lettman

“…We find that previous infections with T. gondii accelerate motor dysfunction in HSP rats, despite robust clearance of the parasite by infected rats. …”
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Optimization of Duck Semen Freezing Procedure and Regulation of Oxidative Stress by Zhicheng Wang, Haotian Gu, Chunhong Zhu, Yifei Wang, Hongxiang Liu, Weitao Song, Zhiyun Tao, Wenjuan Xu, Shuangjie Zhang, Huifang Li

“…In this study, we first used four different freezing procedures (P1–P4) to freeze duck semen and compared their effects on duck sperm quality. Then, the changes in antioxidant indexes in semen were monitored. …”
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Comparative analysis of two TREC/KREC quantification methods for newborn screening of primary immunodeficiency with T- and B-lymphopenia used in Ukraine by Volodymyr Kravets, Ivanna Shymanska, Oksana Boyarchuk, Nataliya Matiytsiv, Oksana Arkhipova, Halyna Makukh

“…Severe combined immunodeficiency (SCID) is the most severe form, characterized by the absence or dysfunction of T and B cells. Without early treatment, most infants with SCID do not survive their first year. …”
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Heat stress-induced CYP1A2 upregulation in sow ovarian granulosa cells by Tae-Gyun Kim, Hyun-Seung Lee, Sung-Ho Kim, Young-Bum Son, Seong-Eun Heo, Do-Yoon Kim, Seung-Joon Kim, Won-Jae Lee

“…These findings emphasize the need for effective thermal management strategies to mitigate heat stress-induced reproductive dysfunction in livestock production.…”
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Autoimmune Hepatitis with Concomitant Idiopathic Thrombocytopenic Purpura Diagnosed by Transjugular Liver Biopsy by Hiromi Fukuda, Kazuhide Takata, Takanori Kitaguchi, Ryo Yamauchi, Hideo Kunimoto, Takashi Tanaka, Keiji Yokoyama, Daisuke Morihara, Yasuaki Takeyama, Satoshi Shakado, Ai Mogi, Shinichi Kora, Kaori Koga, Morishige Takeshita, Kengo Yoshimitsu, Shotaro Sakisaka

“…In conclusion, patients with AIH may sometimes have concomitant ITP. TJLB was effective for making the diagnosis of AIH with severe thrombocytopenia due to ITP.…”
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