Automated quantitative analysis of saccadic characteristics in patients with spontaneous and head-shaking nystagmus by DU Yi, LIU Xingjian, WANG Yu, XU Zhengyan, REN Lili, WU Ziming

“…Conclusion The quantitative tool developed in this study effectively evaluates and distinguishes the characteristics of saccades in compensated and uncompensated states, thereby facilitating the diagnosis and treatment of patients with vestibular dysfunction.…”
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Systemic testosterone for the treatment of female sexual interest and arousal disorder (FSIAD) in the postmenopause by Laura Ribera Torres, Sònia Anglès-Acedo, Laura López Chardi, Eduard Mension Coll, Camil Castelo-Branco

“…Introduction Female sexual interest and arousal disorder (FSIAD) is the most prevalent female sexual dysfunction in the postmenopause.Objective The aim of this review is to provide a summary of the currently available evidence on the use of testosterone in the treatment of FSIAD in postmenopausal women.Methods A narrative review on the topic was performed. …”
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A Case Report on the Thyroid and Eye Connection: A Deep Dive into Evaluation and Treatment Strategies by Iqra Mushtaq, Kalibo Jakhalu, Tushar Agrawal, Gufran Ali Kamdar

“…These patterns emphasise the importance of recognising thyroid dysfunction in orbitopathy management which includes treating the underlying thyroid dysfunction, using corticosteroids to reduce inflammation, and applying artificial tears for symptomatic relief. …”
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Differences in fat distribution between metabolically unhealthy people with normal weight versus obesity, NHANES 2011–2018 by Rajesh Garg, Seerat Anand, Tejasvi Pasupneti, Youngju Pak, Sreevastav Teja Kalangi

“…The differences in android and gynoid fat patterns between MUL and MUO groups suggest different mechanisms of metabolic dysfunction in people who are lean versus those with obesity.…”
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Inter-Organelle Crosstalk in Oxidative Distress: A Unified TRPM2-NOX2 Mediated Vicious Cycle Involving Ca²⁺, Zn²⁺, and ROS Amplification by Esra Elhashmi Shitaw, Maali AlAhmad, Asipu Sivaprasadarao

“…This “circular domino effect” integrates signals generated across the plasma membrane (Ca²⁺), lysosomes (Zn²⁺), mitochondria (ROS) and nucleus (ADPR), leading to progressive organelle failure, cellular dysfunction, and ultimately cell death. …”
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Metalloproteinases (MMPs) in hypertensive disorders: role, function, pharmacology, and potential strategies to mitigate pathophysiological changes by Soroush Taherkhani, Mohammad Sheibani, Mohammad Sheibani, Ali Mohammadkhanizadeh, Jitka A. I. Virag, Lisandra de Castro Braz, Yaser Azizi

“…Inhibitors of MMPs may help mitigate the adverse effects of hypertension by restoring balance in ECM remodeling processes. …”
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Enhanced External Counterpulsation for Management of Postacute Sequelae of SARS-CoV-2 Associated Microvascular Angina and Fatigue: An Interventional Pilot Study by Eline Wu, Ali Mahdi, Jannike Nickander, Judith Bruchfeld, Linda Mellbin, Kristina Haugaa, Marcus Ståhlberg, Liyew Desta

“…Objective. To explore the effects of EECP on symptom burden, physical capacity, mental health, and health-related quality of life (HRQoL) in patients with PASC-associated angina and microvascular dysfunction (MVD). …”
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Evaluating the link between insulin resistance and cognitive impairment using estimated glucose disposal rate in a non-diabetic aging population: results from the CHARLS by Bingqing Wang, Fei Xu, Minheng Zhang

“…Restricted cubic spline analysis identified non-linear threshold effects, with risk accelerating below certain eGDR levels (P < 0.05). …”
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How does the knowledge level of physicians and nurses working at primary health centers affect their preference for oral contraceptives in an inland Turkish province? by Gamze Dur, Ayşen Mert, Rıza Dur, Mine Kanat Pektas

“…When compared to nurses, there is a significantly higher number of physicians who state that OCPs cause acne, depression, sexual dysfunction, ectopic pregnancy, deep vein thrombosis, breast cancer and liver cancer. …”
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Clinical impact of Wnt5a expression on persistence of acute kidney injury in patients with urosepsis by Jungho Shin, Yoosik Yoon, Dong-Jin Oh

“…Abnormal Wnt5a expression is associated with dysregulated inflammation and organ dysfunction. However, the effect of Wnt5a activation on the duration of organ dysfunction remains unclear. …”
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Identifying and establishing the critical elements of a human cardiac in-vitro model for studying type-II diabetes by Ivana Hernandez, Gobinath Chithiravelu, Andie E. Padilla, Binata Joddar

“…Furthermore, the study assessed the effects of AGEs, glucose shock, and their combination on biomarkers, cardiac myosin heavy chain (MHC) and connexin-43 (Cx-43), in AC16 cells. …”
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Uric Acid Promotes Human Umbilical Vein Endothelial Cell Senescence In Vitro by Katarzyna Lewandowska, Justyna Mikuła-Pietrasik, Krzysztof Książek, Andrzej Tykarski, Paweł Uruski

“…Background/Objectives: Uric acid can act as a prooxidant or an antioxidant; therefore, its effects on human umbilical vein endothelial cells (HUVECs) were investigated to better understand its role in promoting cellular senescence and vascular dysfunction. …”
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Evaluation of the prevalence of MASLD, MASH and liver fibrosis in a Dutch bariatric cohort. by Willy Theel, Willem-Pieter Brouwer, Elisabeth van Rossum, Jan Apers, Susan Ter Borg, Tessa Noordermeer, Manuel Castro Cabezas

“…<h4>Background and aims</h4>The prevalence of metabolic dysfunction-associated steatotic liver disease (MASLD) and metabolic dysfunction-associated steatohepatitis (MASH) in bariatric populations has been widely studied but may vary geographically. …”
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STATUS OF COMPREHENSIVE REHABILITATION ORGANIZATION FOR PATIENTS WITH DENTAL ARCH DEFECTS: SPECIALISTS' PERSPECTIVES by R.V. Tsynkush

“…A significant portion of respondents (81.6%) reported familiarity with modern diagnostic methods and assessing the effectiveness of rehabilitation for patients with temporomandibular joint dysfunction. …”
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Clinical characteristics and epilepsy in genomic imprinting disorders: Angelman syndrome and Prader–Willi syndrome by Tzong-Shi Wang, Wen-Hsin Tsai, Li-Ping Tsai, Shi-Bing Wong

“…PWS is induced by multiple paternal gene dysfunctions, including those in MKRN3, MAGEL2, NDN, SNURF-SNPRPN, NPAP1, and a cluster of small nucleolar RNA genes. …”
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The role of inflammasomes in hepatocellular carcinoma: Mechanisms and therapeutic insights by Valentina Arrè, Roberto Negro, Gianluigi Giannelli

“…Hepatocellular carcinoma is among the most frequent forms of primary liver cancer and develops within a context of chronic inflammation, frequently associated with a multitude of risk factors, including viral infections, metabolic dysfunction-associated fatty liver disease, metabolic dysfunction-associated steatohepatitis and liver fibrosis. …”
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A comprehensive analysis of the impact of smoking on adverse clinical outcomes of steatotic liver diseases by Keungmo Yang, Jaejun Lee, Ji Won Han, Hyun Yang, Seung Yun Chae, Beom Sun Chung, Tom Ryu

“…Objectives: This study investigated the effect of smoking status on various clinical outcomes in MASLD and metabolic dysfunction and alcohol-associated liver disease (MetALD). …”
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Post-viral dysosmia: therapeutic and diagnostic principles by O. V. Zaytseva

“…According to expert estimates, the frequency of olfactory dysfunction in such patients reaches 14-30%. More than 80% of patients with acute sinusitis indicate a concomitant olfactory disorder. …”
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Oxidative Stress and Its Correction in Hemorrhagic Fever With Renal Syndrome by Yu. G. Uskova, V. F. Pavelkina

“…The presence of hepatic dysfunction aggravates the pathological process, delays patients' recovery and requires not only detoxification and antioxidant use, but also appointment of hepatoprotective agents. …”
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Cognitive impairment following maternal separation in rats mediated by the NAD+/SIRT3 axis via modulation of hippocampal synaptic plasticity by Keke Hao, Fashuai Chen, Shilin Xu, Ying Xiong, Rui Xu, Huan Huang, Chang Shu, Yisheng Lv, Gaohua Wang, Huiling Wang

“…The NAD+/SIRT3 axis could be a promising therapeutic target for addressing cognitive dysfunctions, such as those seen in schizophrenia.…”
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