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  1. 4741

    Association between triglyceride-glucose index and 6-month readmission in patients with heart failure: a cohort study by Huibo Li, Yujie Jiang, Dong Zheng, Guixiong Lin, Yanling Feng, Yufeng Zhuo, Peng Zhang

    Published 2025-07-01
    “…BackgroundInsulin resistance (IR) significantly impacts outcomes in heart failure (HF) patients, by the triglyceride-glucose (TyG) index serving as an effective marker of metabolic dysfunction. However, its association with HF readmission risk is still uncertain.MethodsThis study analyzed 901 HF patients using multivariable logistic regression and restricted cubic splines to evaluate the relationship between the TyG index and 6-month readmission risk.ResultsPatients in the lowest TyG quartile (Q1) had a significantly higher risk of 6-month readmission across models: Model 1 [odds ratio (OR) 1.72, 95% confidence interval [(CI) 1.16–2.53; p = 0.007], Model 2 (OR 1.83, 95% CI 1.23–2.72; p = 0.003), and Model 3 (OR 1.71, 95% CI 1.12–2.61; p = 0.012). …”
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  2. 4742

    Subclinical Hypothyroidism in Polycystic Ovary Syndrome: Prevalence and Impact on Metabolic and Cardiovascular risk by Taieb Ach, Rim Dhaffar, Fatma Ben Abdessalem, Wiem Saafi, Imen Halloul, Hamza ElFekih, Ghada Saad, Yosra Hasni

    Published 2025-06-01
    “…Addressing thyroid dysfunction in PCOS patients may be beneficial for more effective management strategies, ultimately improving reproductive, metabolic, and cardiovascular outcomes for affected women.…”
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  3. 4743
  4. 4744

    Optimal Timing of Exercise for Enhanced Learning and Memory: Insights From CA1 and CA3 Regions in Traumatic Brain Injury Model in Male Rats by Forouzan Rafie, Sedigheh Amiresmaili, Mohammad Amin Rajizadeh, Mohammad Pourranjbar, Elham Jafari, Mohammad Khaksari, Sara Shirazpour, Omid Moradnejad, Amir Hossein Nekouei

    Published 2025-03-01
    “…The present study explores the effects of delayed and early exercise on brain damage, cognitive dysfunction, and anxiety behavior using an experimental TBI model. …”
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  5. 4745

    Kleinia (Asteraceae): comprehensive review of ethnomedicinal uses, phytochemical profiles, ethnopharmacological applications, and toxicological insights by Bantayehu Addis Tegegne, Tesfa Begashaw, Wubetu Yihunie Belay, Mengistie Kassahun Tariku, Tirsit Ketsela Zeleke, Mohammed Jemal, Mamaru Getinet, Agumas Alemu Alehegn, Abebe Dagne

    Published 2025-01-01
    “…Literature highlights numerous Kleinia taxa used in traditional medicine for conditions like intestinal parasites, measles, smallpox, diabetes, edema, nerve disorders, sexual dysfunction, gastrointestinal issues, cancer and more. …”
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  6. 4746

    The role of anticoagulants in the treatment of community-acquired pneumonia in patients combined with coronavirus infection by I. M. Fushtei, V. O. Mochonyi, O. V. Soloviov

    Published 2025-02-01
    “…Considerable research interest in determining the role of anticoagulants, especially heparin, in COVID-19 patients is related to their positive effect on the disease course. Apart from well-known anticoagulant effects of unfractionated and low-molecular-weight heparins, they possess excellent pleiotropic properties. …”
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  7. 4747

    Auditory sensory processing measures using EEG and MEG predict symptom recovery in first-episode psychosis with a single-tone paradigm by F. López-Caballero, B.A. Coffman, M. Curtis, A.L. Sklar, S. Yi, D.F. Salisbury

    Published 2025-01-01
    “…Longer DAP showed a similar predictive effect, but this relationship was accounted for by M100. …”
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  8. 4748

    Трансплантация суспензии эндотелиальных клеток в эксперименте ex vivo by B.E. Malyugin, S.A. Borzenok, O.P. Antonova, D.S. Ostrovskii, Z.R. Ebzeeva

    Published 2023-12-01
    “…Purpose. To evaluate effectiveness of corneal CECs suspension transplantation on cadaver eye in ex vivo experiment. …”
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  9. 4749

    New Possibilities for Hyposecretory Dry Eye Treatment by S. V. Yanchenko, A. V. Malyshev, G. R. Odilova, L. M. Petrosyan, M. Yu. Odilov

    Published 2023-10-01
    “…Purpose: to evaluate the effectiveness of a fixed combination of 0.24 % hyaluronic acid, carbomer, glycerol and a lipid component in the hyposecretory dry eye treatment. …”
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  10. 4750

    A Simple Nomogram for Predicting the Development of ARDS in Postoperative Patients with Gastrointestinal Perforation: A Single-Center Retrospective Study by Zhang Z, Zhao H, Zhang Z, Jia L, Long L, Fu Y, Du Q

    Published 2025-01-01
    “…This study aims to develop a predictive model for ARDS in postoperative patients with gastrointestinal perforation to facilitate early detection and effective prevention.Methods: In this single-center retrospective study, clinical data were collected from postoperative patients with gastrointestinal perforation admitted to the ICU in Hebei Provincial People’s Hospital from October 2017 to May 2024. …”
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  11. 4751

    Clinical evaluation of primary endoscopic frontal sinus surgery grade 6 (Draf III) in patients with moderate to severe eosinophilic chronic rhinosinusitis with polyps: a randomized... by Ibrahim Talal Elshamy, Mohammed Hamed Askar, Mohammed Adel Khalifa, Mohammed Osama Tomoum, Mohammed Hesham Ali Hamad

    Published 2024-12-01
    “…Abstract Background Endoscopic sinus surgery (ESS) is an effective treatment for chronic rhinosinusitis (CRS) that does not respond to proper conventional treatment. …”
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  12. 4752

    Small Molecules in Parkinson’s Disease Therapy: From Dopamine Pathways to New Emerging Targets by Hwayoung Lee, Ahmed Elkamhawy, Polina Rakhalskaya, Qili Lu, Hossam Nada, Guofeng Quan, Kyeong Lee

    Published 2024-12-01
    “…By examining both established and emerging targets, we aim to highlight effective strategies and potential directions for future drug development in Parkinson’s disease therapy.…”
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  13. 4753

    Electromyographic Characteristics of a Single Motion Shoulder Exercise: A Pilot Study Investigating a Novel Shoulder Exercise by Michael J Henehan, Tamar Brand-Perez, Jeffrey C Peng, Masaaki Tsuruike

    Published 2022-02-01
    “…A single motion shoulder exercise that effectively activates the rotator cuff and scapular stabilizing muscles, engages the scapulohumeral rhythm, and includes eccentric contractions may be more effective and easier for patients to consistently perform as compared to multiple standard shoulder exercises…”
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  14. 4754

    The Role of 5-Phosphodiesterase Inhibitors (PDE-5I) in Current Benign Prostatic Hyperplasia Treatment: A Narrative Review by Konstantinos Stamatiou, Gianpaolo Perletti, Vittorio Magri, Alberto Trinchieri

    Published 2024-10-01
    “…<i>Conclusions</i>: PDE-5I seems effective in relieving symptoms of some BPH patients when administered as complementary to agents currently used to treat BPH. …”
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  15. 4755

    A Microflow Chip Technique for Monitoring Platelets in Late Pregnancy: A Possible Risk Factor for Thrombosis by He C, Ma H, Zhang T, Liu Y, Zhang C, Deng S

    Published 2025-01-01
    “…However, microfluidic technology can simulate a more realistic in vivo shear rate environment, providing more effective clinical application data and a theoretical basis for the diagnosis and prevention of platelet dysfunction and thrombotic diseases during pregnancy.Keywords: microfluidic chip, late pregnancy, platelets, adhesion aggregation, thrombosis…”
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  16. 4756

    Cu-DHM nanozymes treat flap ischemia-reperfusion injury by amplifying immune modulation in a cascade manner and inhibiting cell apoptosis by Xinyu Zhao, Shuo Zhang, Min Wang, Qingrong Li, Xiaolong Wei, Xu-Lin Chen, Xianwen Wang

    Published 2025-09-01
    “…Flap ischemia-reperfusion (I/R) injury triggers intense inflammatory responses and oxidative stress following blood flow restoration, often resulting in tissue dysfunction. Currently, no effective and widely recognized treatment strategies are available in clinical practice. …”
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  17. 4757

    Intraductal chemotherapy for triple-negative breast cancer: a pathway to minimally invasive clinical treatment by Xinhong Wu, Feng Yuan, Liantao Guo, Dongcheng Gao, Weijie Zheng, Chuang Chen, Hongmei Zheng, Jianhua Liu

    Published 2025-02-01
    “…Echocardiographic analysis confirmed that intraductal administration of eribulin (ERI) or doxorubicin (DOX) did not cause cardiac dysfunction or apoptosis. Our results demonstrate that intraductal delivery of ERI and DOX significantly enhances anti-tumor and anti-metastatic effects. …”
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  18. 4758

    Multiple skip incision skin-sparing debridement for perianal necrotizing fasciitis: a retrospective study by Qing Long, Chaochi Yue, Bin He, Jun Li

    Published 2025-08-01
    “…Conclusion MSISSD appears to be a promising and effective method for skin protection debridement, which can effectively protect the skin while ensuring adequate drainage, and rarely causing severe anal dysfunction.…”
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  19. 4759

    Nutritional management of pediatric nephrotic syndrome regarding oxidative stress and antioxidant balance by Elena Jechel, Alin Horatiu Nedelcu, Felicia Dragan, Vasile Valeriu Lupu, Iuliana Magdalena Starcea, Adriana Mocanu, Solange Tamara Rosu, Violeta Streanga, Ruxandra Russu, Ginel Baciu, Ciprian Danielescu, Delia Lidia Salaru, Ionela Daniela Morariu, Olga Cirstea, Emil Anton, Ancuta Lupu

    Published 2025-05-01
    “…The translational perspectives of antioxidant therapy are also discussed, in the context of the urgent need for effective adjuvant strategies with a safety profile superior to conventional therapies. …”
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  20. 4760

    NFκB1: a common biomarker linking Alzheimer's and Parkinson's disease pathology by Adam Cunningham, Emma Barrett, Sebastian Risch, Peter H. U. Lee, Peter H. U. Lee, Chan Lee, Abhay Moghekar, Prabir Patra, Joon W. Shim

    Published 2025-05-01
    “…These findings highlight candidate biomarkers and suggest that therapeutic strategies targeting mitochondrial integrity and neuroinflammation may be effective in AD and PD.…”
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