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4701
The association between sleep and burnout in psychiatric nurses: a survey from China
Published 2025-06-01“…Implementing personalized strategies to improve sleep hygiene could serve as an effective means to mitigate burnout and support the mental health of psychiatric nurses. …”
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4702
Uricase-Expressing Engineered Macrophages Alleviate Murine Hyperuricemia
Published 2024-11-01“…In terms of safety, engineered macrophages did not cause liver or kidney dysfunction in mice, nor did they induce systemic immune response. …”
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4703
Independent and interactive roles of hirudin and HMGB1 interference in protecting renal function by regulating autophagy, apoptosis, and kidney injury in chronic kidney disease
Published 2025-04-01“…Hirudin, a potent thrombin inhibitor, has demonstrated antifibrotic and anti-inflammatory properties, but its effects on autophagy and apoptosis in CKD remain unclear. …”
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4704
Translational interdisciplinary research on human chorionic gonadotropin’s enhancement of neuroendocrine crosstalk: a novel medical hypothesis for systemic adjunctive treatment of...
Published 2025-04-01“…Continuous exploration of neuroendocrine dysfunctions in mental disorders using advanced tools from neuroscience, endocrinology, and psychiatry can provide new pathways for more effective and personalized treatments. …”
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4705
Comparison of the efficacy of ultrasound-guided dextrose 25% hypertonic prolotherapy and intra-articular normal saline injection on pain, functional limitation, and range of motion...
Published 2025-03-01“…Dextrose prolotherapy (DPTx) has been shown to have a beneficial effect on knee OA in the long-term. In this randomized controlled trial (RCT), we aimed to compare DPTx with intra-articular normal saline injection (IA-NS) to treat knee OA in terms of effectiveness and patient-reported outcomes. …”
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4706
The Prognostic Value of the EASIX Score in Patients with Metastatic Pancreatic Cancer
Published 2025-07-01“…The identification of accessible, cost-effective prognostic biomarkers is critical for optimizing treatment strategies. …”
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4707
Subchronic and Chronic Toxicity Assessment of Sublancin in Sprague–Dawley Rats
Published 2025-05-01“…The no-observed-effect level (NOEL) was determined to be 50,000 mg/kg for both study periods. …”
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4708
Etiological and immunopathogenetic aspects of multiorgan failure development in coronavirus disease (COVID-19)
Published 2024-07-01“…The use of modern knowledge about the immunopathogenesis of COVID-19 would help to estimate the risk for severe infection and the possible development of complications, allowing for the timely implementation of effective pathogenetic therapy.…”
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4709
The role of Adipocytokines, Vitamin D, and C in Colorectal Cancer
Published 2023-06-01“…The findings in the current study suggest an imperative biochemical role of Adipocytokines (Adiponectin and Leptin) and Adipose tissue dysfunction in the pathogenesis of CRC patients. Furthermore, decreased serum levels of Vitamin D and C reduce their effective anti-cancer effects, allowing Colorectal malignant neoplasms to survive and develop. …”
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4710
Molecular Mechanisms of Neonatal Brain Injury
Published 2012-01-01“…The concept that most of the injury develops with a delay after the insult makes it possible to provide effective neuroprotective treatment after the insult. …”
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4711
Pan-caspase inhibitor protects against noise-induced hearing loss in a rodent model
Published 2025-02-01“…BackgroundDespite the high prevalence of noise-induced hearing loss (NIHL), no effective treatments exist currently. Underlying mechanisms behind NIHL include elevated reactive oxygen species and inflammation, all which ultimately lead to cellular apoptosis. …”
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4712
Beta-Thalassemia and Male Infertility: Unraveling the Oxidative Stress Connection—An Up-to-Date Review
Published 2024-12-01“…While antioxidant therapies may offer a partial remedy, further research is necessary to understand OS’s mechanisms in TM and develop effective fertility treatments. This review highlights the need for personalized antioxidant approaches to improve reproductive outcomes in this population.…”
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4713
Enhanced neuroplasticity and gait recovery in stroke patients: a comparative analysis of active and passive robotic training modes
Published 2025-05-01“…Abstract Background Stroke is a leading cause of long-term disability, with lower limb dysfunction being a common sequela that significantly impacts patients' mobility and quality of life. …”
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4714
Deubiquitinase Ubiquitin‐Specific Protease 29 Ameliorates Pathological Cardiac Hypertrophy through Inhibiting Transforming Growth Factor β‐Activated Kinase 1
Published 2025-03-01“…Moreover, genetic knockout of USP29 in mice exacerbated transverse aortic constriction‐induced heart hypertrophy, dysfunction, and fibrosis, whereas overexpression of USP29 in cardiomyocytes using adeno‐associated virus 9 effectively attenuated the hypertrophic response. …”
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4715
Continuous Estimation of Swallowing Motion With EMG and MMG Signals
Published 2025-01-01“…Oropharyngeal dysphagia (OD) is a symptom of swallowing dysfunction that is associated with aspiration, severe respiratory complications, and even death. …”
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4716
Rapid, Precise, and Clinically Relevant Quantification of Urinary Albumin and Creatinine Using a NanoDrop UV/Vis Spectrophotometer
Published 2025-05-01“…Albuminuria is a sensitive biomarker of kidney dysfunction, and the albumin/creatinine ratio (ACR) is an essential measure for monitoring diabetic kidney disease (DKD). …”
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4717
Stent-assisted coiling of hepatic artery pseudoaneurysm in a liver transplant recipient
Published 2025-08-01“…Case presentation We report a case of a 45-year-old male with metabolic dysfunction-associated steatotic liver disease who underwent living donor liver transplantation using a right lobe graft. …”
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4718
Development of an immune-related gene signature applying Ridge method for improving immunotherapy responses and clinical outcomes in lung adenocarcinoma
Published 2025-05-01“…Considering the critical role of tumor infiltrating lymphocytes in effective immunotherapy, this study was designed to screen molecular markers related to tumor infiltrating cells in LUAD, aiming to improve immunotherapy response during LUAD therapy. …”
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4719
AI‐Based Platelet‐Independent Noninvasive Test for Liver Fibrosis in MASLD Patients
Published 2025-04-01“…Additionally, elastography, while effective, is costly and less accessible in routine practice. …”
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4720
Non-selective laryngeal reinnervation in thyroid surgery
Published 2020-10-01“…The method of non-selective laryngeal reinnervation by the anastomosis “ansa cervicalis – recurrent laryngeal nerve” is an effective method for correcting phonatory disorders in unilateral abduction paralysis of the larynx during primary and repeated thyroid surgery and can improve the voice function of the larynx to almost normal state without negative changes in the external respiration function.…”
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