Mesenchymal stem cell exosomes therapy for the treatment of traumatic brain injury: mechanism, progress, challenges and prospects by Ming-wei Liu, Hua Li, Gui-fei Xiong, Bin-ran Zhang, Qiu-juan Zhang, Shu-ji Gao, Yan-lin Zhu, Lin-ming Zhang

“…Under the influence of multiple mechanisms, TBI can cause synaptic dysfunction, protein aggregation, mitochondrial dysfunction, oxidative stress, and neuroinflammatory cascade reactions, resulting in a high disability and mortality rate for patients and a heavy burden on families and society. …”
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COVID-19 and Diabetes: Persistent Cardiovascular and Renal Risks in the Post-Pandemic Landscape by Tzu-Shan Huang, Jo-Yen Chao, Ho-Hsiang Chang, Wei-Ren Lin, Wei-Hung Lin

“…This increased risk is mediated through immune dysfunction, chronic inflammation, hyperglycemia, dysregulation of renin-angiotensin system dysregulation, endothelial dysfunction, and hypercoagulability. …”
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A Novel Approach to Repositioning Peritoneal Dialysis Catheters by Xiuling Chen, Nan Wang, Yurong Zou, Jin Chen, Hui Gao, Guisen Li, Junru Wang

“…Conclusion: This new method for resetting dysfunctional PD catheters demonstrates technical feasibility, simplicity, cost-effectiveness, and safety. …”
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Posttraumatic Period in Cardiac Contusion (Experimental Study) by O. V. Korpacheva, V. T. Dolgikh

“…Conclusion. The hemodynamic effects of hypoxen can substantially limit the possibility of using the agent to diminish the degree of posttraumatic cardiac dysfunction. …”
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Loss of Corneal Endothelial Cells during Glaucoma Surgery by I. V. Shaposhnikova, I. R. Gazizova, A. V. Kuroyedov, A. V. Seleznev, D. N. Lovpache

“…The cornea is a highly sensitive tunic of the eyeball, endothelium is one of the target organs in the formation of pathological changes in primary open-angle glaucoma, and endothelial dysfunction, according to many authors, plays a significant role in its pathogenesis. …”
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Spatial Cognition in Adult and Aged Mice Exposed to High-Fat Diet. by James P Kesby, Jane J Kim, Miriam Scadeng, Gina Woods, Deborah M Kado, Jerrold M Olefsky, Dilip V Jeste, Cristian L Achim, Svetlana Semenova

“…Environmental stressors, such as high-fat diet (HFD) exposure, that produce a diabetic phenotype and metabolic dysfunction may indirectly lead to exacerbated brain aging and promote the development of cognitive deficits. …”
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Ginsenoside Rg1 Alleviates Blood–Milk Barrier Disruption in Subclinical Bovine Mastitis by Regulating Oxidative Stress-Induced Excessive Autophagy by Shanshan Yang, Zihao Fang, Hongwei Duan, Weitao Dong, Longfei Xiao

“…As a critical disease usually infected by <i>Staphylococcus aureus</i>, with a worldwide effect on dairy animals, subclinical mastitis is characterized by persistence and treatment resistance. …”
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A novel evaluation approach for functional impairment in subacromial impingement syndrome: focus on Temporal Summation of Activity-related Pain (TSAP) by Katsuyoshi Tanaka, Shota Oda, Masashi Izumi

“…We analyzed the association between the parameters and the impact of movement-evoked pain on upper extremity dysfunction assessed using Quick Disabilities of the Arm, Shoulder, and Hand (QuickDASH). …”
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Hemostasis disorder as a reason of periodontitis in patients with diabetes mellitus by E. A. Shevchenko, T. E. Potemina, E. G. Ivanova

“…The aim of the study hemostasis indicators associated with endothelial dysfunction to study the etiology of periodontitis in patients with type II diabetes mellitus. …”
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Interaction of vitamin D, homocystein and dental diseases by O. V. Kuriata, M. M. Hrechanyk

“…The aim of the study was to estimate the effect of ursodeoxycholic acid (UDCA) on the lipid profile, endothelial dysfunction and insulin resistance in patients with coronary heart disease (CHD) in combination with non-alcoholic steatosis. …”
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Evaluation of blood parameters in the management of patients with thyroid disease by Abazar Yari, Morteza Ahmadi, Mahdieh Mehrpouri

“…Therefore, this study aimed to evaluate the effect of thyroid dysfunction on various blood parameters. …”
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Splenomegaly and thrombocytopenia in patients with liver cirrhosis by Đorđević Jelena, Svorcan Petar, Vrinić Dušica, Dapčević Branka

“…We did not find any significant correlation between hepatic dysfunction and spleen size (p = 0.9), and between hepatic dysfunction and thrombocytopenia (p = 0.17). …”
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Neurophysiologic features in glutaric aciduria type I by Dilek Yalnizoğlu, Neriman Sari, Güzide Turanli, Turgay Coşkun, Meral Topçu

“…We believe this finding was due to medication effect, and that what we observed was an exaggarated response to benzodiazepine. …”
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Melatonin as a Therapeutic Adjunct in Obstructive Sleep Apnea: A Review of Potential Benefits by Jose Javier Lasala, Don Eliseo III Lucero-Prisno

“…These neuroprotective effects may counteract the cognitive impairments frequently observed in OSA patients. …”
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Pharmacological Activation of Rev-erbα Attenuates Doxorubicin-Induced Cardiotoxicity by PGC-1α Signaling Pathway by Runmei Zou, Shuo Wang, Hong Cai, Yuwen Wang, Cheng Wang

“…SR9009 alleviated doxorubicin-induced cell apoptosis, morphological disorder, mitochondrial dysfunction, and oxidative stress in H9c2 cells and C57BL/6 mice. …”
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Cognitive impairment in Sjogren's syndrome: Interplay between BACE1 activity, inflammatory blood biomarkers and neurocognitive testing. by Alireza Kooshki, Mohammad Yousefi, Reyhane Farmani, Hamid Kabiri-Rad, Hossien Nezami, Amirhosein Zardast, Zeinab Saremi

“…<h4>Background</h4>Sjogren's syndrome (SS) is considered as a chronic, autoimmune disorder, that can present with various manifestations both intra and extra-glandular. Cognitive dysfunction is pivotal in recognizing neurological complications in SS.…”
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Mild hyperbaric hyperoxia improves aerobic capacity and suppresses cardiopulmonary stress during the maximal cycle-ergometer test. by Kazufumi Hisamoto, Naoki Okubo, Mako Fujita, Hideki Fukushima, Yoshinori Okizuka, Takashi Yamanaka, Tomoyuki Matsui, Toru Morihara, Tatsuya Hojo, Yoshiyuki Fukuoka, Kenji Takahashi

“…Although further clinical research targeting other populations is needed to apply mild hyperbaric hyperoxia in clinical practice, due to its positive effects on WVT and cardiopulmonary stress, the HYPER oxygen condition may potentially be used to enhance aerobic capacity and make individuals with cardiopulmonary dysfunction exercise safely.…”
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An efficient enhanced stacked auto encoder assisted optimized deep neural network for forecasting Dry Eye Disease by Steffi Rajan, Suresh Ponnan

“…Abstract Meibomian Gland Dysfunction (MGD) and Dry Eye Disease (DED) comprise two of the most significant eye diseases, impacting millions of sufferers worldwide. …”
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The ETS-Domain Transcription Factor Elk-1 Regulates COX-2 Gene Expression and Inhibits Glucose-Stimulated Insulin Secretion in the Pancreatic β-Cell Line INS-1 by Xiong-Fei Zhang, Yi Zhu, Wen-Biao Liang, Jing-Jing Zhang

“…We first investigated the effects of Elk-1 on COX-2 transcriptional regulation and expression in INS-1 cells. …”
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The Importance of Selecting Permanent Pacemaker, Evaluating the Heart and Assessing Quality of Life in Cardiac Patient by Ika Prasetya Wijaya

“…Pacing burden >40% causes subclinical left ventricular systolic dysfunction after a month of PPM implantation with decreased GLS in apical RV pacing. …”
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