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Suggested Topics within your search.
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4621
Pathological anatomy of the new coronavirus infection COVID-19 according to autopsy materials 2020
Published 2022-04-01“…These factors in total result in organ dysfunction.Methods and materials. We examined 96 pathological studies’ protocols of patients who died from the PCR-confirmed new coronavirus infection. …”
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4622
Targeting Platelet Activating Factor Signaling for Therapeutic Benefits in Neurodegenerative Disorders
Published 2025-04-01“…It explores the potential of these inhibitors to offer significant preventative and therapeutic benefits against NDs, likely through anti-inflammatory anti-aging effects and by slowing down the disease progression and preserving cognitive and motor dysfunction. …”
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4623
Hippocampal Neurogenesis, Cognitive Deficits and Affective Disorder in Huntington's Disease
Published 2012-01-01“…There are a range of different brain regions, including the cerebral cortex and striatum, known to be affected in HD, with evidence for hippocampal dysfunction accumulating in recent years. In this review we will focus on hippocampal abnormalities, in particular, deficits of adult neurogenesis. …”
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4624
Depression and TMD among elderly: A pilot study
Published 2012-11-01“… Objectives: Temporomandibular dysfunction (TMD) is a painful syndrome that affects orofacial region, with deleterious effects in patients’ quality of life. …”
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4625
In Silico Investigation of the RBC Velocity Fluctuations in Ex Vivo Capillaries
Published 2025-07-01“…This velocity fluctuation is aggravated by high hematocrit conditions, without any further effect on RDW. These results can provide a better understanding of the underlying mechanisms of pathologically high capillary transit time heterogeneity that results in microcirculatory dysfunction.…”
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4626
Hypothyroidism and Leptin in Iraqi Patients with Chronic Kidney Disease
Published 2021-06-01“…The present study aims at assessing the effects of chronic kidney disease (CKD) on thyroid hormone and leptin by evaluating the level of: leptin hormone along with thyroid hormone in CKD patients. …”
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4627
Pathogenesis of obstetric and perinatal complications in metabolic syndrome
Published 2025-06-01“…Failure to adequately adapt to increased nutritional load results in adipose tissue dysfunction which triggers a cascade of lipotoxic effects on other organs, leading to insulin resistance, diabetes mellitus, and related metabolic complications. …”
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4628
Cancer, deuterium, and gut microbes: A novel perspective
Published 2025-03-01“…This gas is recycled into organic matter that supplies deupleted nutrients to the host, such as acetate, butyrate, and choline. Mitochondrial dysfunction is associated with many chronic diseases, most notably, cancer. …”
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4629
Repetitive transcranial magnetic stimulation for motor function in stroke: a systematic review and meta-analysis of randomized controlled studies
Published 2025-02-01“…Abstract Objective This study aimed to systematically evaluate the safety and effectiveness of repetitive transcranial magnetic stimulation (rTMS) in treating motor dysfunction in stroke patients. …”
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4630
Mitophagy Protects Against Cisplatin-Induced Injury in Granulosa Cells
Published 2025-04-01“…Mitophagy, a key cellular self-protection mechanism that selectively removes damaged mitochondria, was activated following cisplatin treatment, mitigating its detrimental effects on KGN cells. Activation of mitophagy with urolithin A (UA) ameliorated cisplatin-induced mitochondrial dysfunction and apoptosis, whereas inhibition of mitophagy with cyclosporine A (CsA) exacerbated these effects. …”
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4631
Central hemodynamics in elderly patients with arterial hypertension treated with perindopril A/indapamide (Noliprel A/forte) and lowintensity laser therapy
Published 1970-01-01“…The combination of Noliprel A/forte and LILT had additive beneficial effects on morphological and functional components of intracardiac hemodynamics, with LV and RF systolic function improvement and even more pronounced regression of LV and RF diastolic dysfunction. …”
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4632
RECENT ASPECTS OF CARDIAC REMODELING IN PATIENTS WITH CHRONIC OBSTRUCTIVE PULMONARY DISEASE
Published 2018-07-01“…Sarcopenia related to the inflammatory-catabolic state in COPD and hypoxia could play an important role regarding LV systolic dysfunction. Recent data reported the effects of long-acting bronchodilators on reducing lung hyperinflation (inducing lung deflation). …”
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4633
Targeting mitochondrial biogenesis: Chandraprabha Vati in the management of metabolic syndrome
Published 2025-08-01“…Conclusion: CPV could effectively combat mitochondrial dysfunction and chronic low-grade inflammation associated with MetS in rats.…”
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4634
Selenium Supplementation in Pregnancy-Maternal and Newborn Outcomes
Published 2022-01-01“…Maternal studies reported the effects of selenium supplementation in the prevention of thyroid dysfunction, gestational diabetes, pregnancy-induced hypertension/preeclampsia, oxidative stress, postpartum depression, premature rupture of membranes, intrauterine growth retardation, breastmilk composition, and HIV-positive women. …”
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4636
Left ventricular global longitudinal strain in patients treated with immune checkpoint inhibitors
Published 2024-12-01“…BackgroundImmune checkpoint inhibitors (ICI) are generally associated with rare cardiac side effects, yet instances like myocarditis can be fatal. …”
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4637
Association between oxidative balance score and lung function and FeNO and mortality in the US population
Published 2025-04-01“…Conversely, the relationship between OBS and FVC levels was influenced by gender and BMI. The effects of the overall OBS, lifestyle OBS, and dietary OBS on lung function parameters were independent of whether participants had restrictive ventilatory dysfunction or obstructive ventilatory dysfunction.In addition, both the overall OBS and dietary OBS demonstrated significant inverse associations with all-cause mortality, whereas no statistically significant relationships were observed between these scores and respiratory-related mortality. …”
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4638
IL-35 Ameliorates Myocardial Strain in Mice with T2DM-Induced Cardiac Injury: Assessment by Layer-Specific Strain
Published 2025-05-01“…Interleukin-35 (IL-35) can suppress inflammatory processes and ameliorate endothelial dysfunction. This study aimed to evaluate the effect of IL-35 treatment on diabetic mice with diabetes-induced cardiac injury using layer-specific strain analysis.Patients and Methods: Twenty-six mice were allocated into three groups: the control group (CON, n=10), the diabetic group (DM, n=10), and the diabetic group treated with IL-35 (DMIL, n=6). …”
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4639
Evaluating the diagnostic performance of adult sepsis event criteria in the emergency department: impact of including isolated serum lactate elevations
Published 2025-08-01“…Moreover, the impact of including isolated serum lactate elevation as a marker of organ dysfunction in eSOFA has not been systematically evaluated. …”
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4640
Clinical Value of Continuous Fascia Iliaca Compartment Block in Perioperative Management of Elderly Patients with Intertrochanteric Fracture: A Propensity Score-Matched Retrospecti...
Published 2025-05-01“…Complication rates were comparable between groups (22.5% vs 17.5%, P = 0.576).Conclusion: CFICB effectively improves postoperative pain management, reduces cognitive dysfunction incidence, and enhances early functional recovery in elderly patients with intertrochanteric fractures, while maintaining a favorable safety profile.Keywords: continuous fascia iliaca compartment block, intertrochanteric fracture, cognitive function, postoperative pain, hip joint function, elderly patients, regional anesthesia…”
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