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4581
The role of neuroimaging in Alzheimer’s disease: implications for the diagnosis, monitoring disease progression, and treatment
Published 2025-02-01“…It presents a significant challenge in terms of accurate diagnosis, disease progression monitoring, and the development of effective treatments. This article addresses the role of neuroimaging as an advancing tool for diagnosis, monitoring progression, and treatment of AD. …”
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4582
Analysis of clinical and microbiological characteristics of invasive Klebsiella pneumoniae liver abscess syndrome
Published 2025-04-01“…Patients with IKPLAS had a higher risk of developing multiple organ dysfunction (MODS), and a PCT ≥ 10 ng/mL was identified as an independent risk factor for MODS (p = 0.01). …”
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4583
The double life of glucose metabolism: brain health, glycemic homeostasis, and your patients with type 2 diabetes
Published 2024-12-01“…Moreover, these studies demonstrated that glucose-lowering agents are not equally effective at preventing cognitive dysfunction. Glucagon-like peptide-1 (GLP-1) receptor analogs and sodium glucose cotransporter 2 inhibitors (SGLT2is) appear to afford the greatest protection; metformin and dipeptidyl peptidase 4 inhibitors (DPP-4is) also significantly improved cognitive outcomes. …”
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4584
Transcatheter Aortic Valve Durability: Focus on Structural Valve Deterioration
Published 2025-07-01“…Multiple mechanisms may lead to bioprosthetic valve dysfunction, including structural valve deterioration, thrombosis, endocarditis, and nonstructural valve deterioration. …”
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4585
Radiographic evaluation of temporomandibular joint in patients with posterior direct restorations
Published 2020-03-01“…The process of tooth wear and direct restorations can progress and cause dysfunction of the temporomandibular joint (TMJ), the assessment of which is quite effective using cone beam computed tomography (CBCT).The aim is to study of the morphological parameters of the condyles and their relationship with the articular fossa of the TMJ using CBCT in patients with direct restorations in the masticatory region of the upper and lower jaws.Materials and methods. …”
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4586
Intracardiac abscess in the clinical course of infective endocarditis complicated by acute heart failure
Published 2024-12-01“…Increased blood lactate levels suggest tissue hypoxia and organ dysfunction. Acute heart failure was characterized by elevated levels of NT-proBNP, troponin, and creatine phosphokinase-MB. …”
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4587
Lipid droplet accumulation impairs osseointegration by disturbing the osteogenesis-osteoclasis balance on titanium implant surface in hyperlipidemia
Published 2025-05-01“…Abstract Background Effective osseointegration is a crucial factor for the success of implant restoration, and hyperlipidemia significantly impairs osseointegration. …”
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4588
Artificial intelligence empowered voice generation for amyotrophic lateral sclerosis patients
Published 2025-01-01“…Abstract Amyotrophic Lateral Sclerosis (ALS) is a neurodegenerative disease that can result in a progressive loss of speech due to bulbar dysfunction, which can have significant negative impact on the patient’s mental well-being. …”
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4589
Late non-infectious lung damage in children after allogeneic hematopoietic stem cells transplantation
Published 2015-06-01“…HSCT complications include the possibility of prolonged immunodeficiency, alloand autoimmune reactions and various organs dysfunction. These conditions require careful monitoring by specialists, early diagnosis and appropriate treatment. …”
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4590
Strength training improves heart function, collagen and strength in rats with heart failure
Published 2024-02-01“…Although physical exercise is a well-recognized effective non-pharmacological therapy for cardiovascular diseases, the effects of strength training (ST) on the structural and functional aspects of cardiac remodeling need to be further documented. …”
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4591
Early identification of macrophage activation syndrome in adult-onset Still’s disease: a case report and literature review
Published 2025-01-01“…The application of diagnostic scoring systems like the HScore and MS score is essential for prompt diagnosis and effective treatment, ultimately improving patient survival rates.…”
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4592
Psychometric Properties of the Persian Version of the Frontal Assessment Battery in Patients With Traumatic Brain Injury
Published 2025-03-01“…Conclusion: The P-FAB is a valid, reliable, and effective tool for assessing executive dysfunction in PwTBI.…”
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4593
Preclinical Parkinson’s Disease Models for Non-Motor Symptoms: Research Recommendations from a Systematic Review
Published 2025-06-01“…However, PD is increasingly recognized as a multisystem disorder, where non-motor symptoms such as cognitive impairment, mood disturbances, sleep disorders, and autonomic dysfunction significantly impact patients’ quality of life. …”
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4594
Radiation-induced premature ovarian failure: focus on the role of ovarian inflammatory signaling pathways
Published 2023-12-01“…Radiation therapy, an effective treatment modality for many types of cancer, often carries a heavy cost for young women. …”
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4595
Atrial Fibrillation in Diabetes: Pathogenesis and Targeted Rhythm Control Strategies
Published 2025-07-01“…Conventional rhythm control strategies remain less effective in diabetic individuals, underscoring the need for innovative, substrate-targeted interventions. …”
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4596
Impaired LTB4-induced neutrophil chemotactic directionality in myelodysplastic neoplasms patients
Published 2025-12-01“…These insights hold significant clinical implications for managing infections in MDS patients, underscoring the importance of targeting specific neutrophil defects for more effective therapeutic strategies.…”
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4597
The Hidden Burden: Gastrointestinal Involvement in Lysosomal Storage Disorders
Published 2025-05-01“…Results: The pathogenesis of GI involvement in LSDs varies and encompasses substrate accumulation in enterocytes, mesenteric lymphadenopathy, mass effects, smooth muscle dysfunction, vasculopathy, neuropathy, inflammation and alterations to the microbiota. …”
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4598
Surface area outcomes in EUS-guided liver biopsy: a comparative study of Franseen and Fork-tip needles
Published 2025-05-01“…Abstract Background The practice of endoscopic ultrasound-guided liver biopsy (EUS-LB) is becoming more common due to its proven safety and effectiveness. For accurate diagnosis, it is vital to secure ample tissue specimens. …”
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4599
Does the hepatologist still need to rely on aminotransferases in clinical practice? A reappraisal of the role of a classic biomarker in the diagnosis and clinical management of chr...
Published 2025-01-01“…ALT, a sensitive and cost-effective marker of liver injury, remains pivotal in predicting clinical outcomes and guiding interventions in several chronic liver diseases including metabolic dysfunction-associated steatotic liver disease, and chronic viral hepatitis. …”
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4600
Home nasogastric tube program for NICU infants: a seven year retrospective outcome analysis
Published 2025-04-01“…There were no emergency department visits related to feeding tube dysfunction or nasogastric (NG) tube equipment malfunctions. …”
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