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  1. 4581

    The role of neuroimaging in Alzheimer’s disease: implications for the diagnosis, monitoring disease progression, and treatment by Julius Mulumba, Rui Duan, Bo Luo, Jiang Wu, Muhammad Sulaiman, Feng Wang, Yong Yang

    Published 2025-02-01
    “…It presents a significant challenge in terms of accurate diagnosis, disease progression monitoring, and the development of effective treatments. This article addresses the role of neuroimaging as an advancing tool for diagnosis, monitoring progression, and treatment of AD. …”
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    Article
  2. 4582

    Analysis of clinical and microbiological characteristics of invasive Klebsiella pneumoniae liver abscess syndrome by Li Gu, Yue Wang, Han Wang, Dong Xu

    Published 2025-04-01
    “…Patients with IKPLAS had a higher risk of developing multiple organ dysfunction (MODS), and a PCT ≥ 10 ng/mL was identified as an independent risk factor for MODS (p = 0.01). …”
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  3. 4583

    The double life of glucose metabolism: brain health, glycemic homeostasis, and your patients with type 2 diabetes by Stanley S. Schwartz, Mary E. Herman, May Thet Hmu Tun, Eugenio Barone, D. Allan Butterfield

    Published 2024-12-01
    “…Moreover, these studies demonstrated that glucose-lowering agents are not equally effective at preventing cognitive dysfunction. Glucagon-like peptide-1 (GLP-1) receptor analogs and sodium glucose cotransporter 2 inhibitors (SGLT2is) appear to afford the greatest protection; metformin and dipeptidyl peptidase 4 inhibitors (DPP-4is) also significantly improved cognitive outcomes. …”
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  4. 4584

    Transcatheter Aortic Valve Durability: Focus on Structural Valve Deterioration by Antonin Trimaille, Adrien Carmona, Sandy Hmadeh, Dinh Phi Truong, Benjamin Marchandot, Shinnosuke Kikuchi, Kensuke Matsushita, Patrick Ohlmann, Valérie Schini‐Kerth, Josep Rodés‐Cabau, Philippe Pibarot, Olivier Morel

    Published 2025-07-01
    “…Multiple mechanisms may lead to bioprosthetic valve dysfunction, including structural valve deterioration, thrombosis, endocarditis, and nonstructural valve deterioration. …”
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    Article
  5. 4585

    Radiographic evaluation of temporomandibular joint in patients with posterior direct restorations by I. N. Bagdasarova, A. A. Gevorkyan, O. V. Pilshchikova, N. N. Fedotova, A. S. Karnaeva, L. A. Kozhevnikova, V. M. Slonova

    Published 2020-03-01
    “…The process of tooth wear and direct restorations can progress and cause dysfunction of the temporomandibular joint (TMJ), the assessment of which is quite effective using cone beam computed tomography (CBCT).The aim is to study of the morphological parameters of the condyles and their relationship with the articular fossa of the TMJ using CBCT in patients with direct restorations in the masticatory region of the upper and lower jaws.Materials and methods. …”
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  6. 4586

    Intracardiac abscess in the clinical course of infective endocarditis complicated by acute heart failure by Собіров Барно Бобір огли

    Published 2024-12-01
    “…Increased blood lactate levels suggest tissue hypoxia and organ dysfunction. Acute heart failure was characterized by elevated levels of NT-proBNP, troponin, and creatine phosphokinase-MB. …”
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  7. 4587

    Lipid droplet accumulation impairs osseointegration by disturbing the osteogenesis-osteoclasis balance on titanium implant surface in hyperlipidemia by Ya-nan Wang, Shiyue Liu

    Published 2025-05-01
    “…Abstract Background Effective osseointegration is a crucial factor for the success of implant restoration, and hyperlipidemia significantly impairs osseointegration. …”
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    Article
  8. 4588

    Artificial intelligence empowered voice generation for amyotrophic lateral sclerosis patients by Stefano Regondi, Giordana Donvito, Emanuele Frontoni, Milutin Kostovic, Fabio Minazzi, Sébastien Bratières, Massimiliano Filosto, Raffaele Pugliese

    Published 2025-01-01
    “…Abstract Amyotrophic Lateral Sclerosis (ALS) is a neurodegenerative disease that can result in a progressive loss of speech due to bulbar dysfunction, which can have significant negative impact on the patient’s mental well-being. …”
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    Article
  9. 4589

    Late non-infectious lung damage in children after allogeneic hematopoietic stem cells transplantation by Yu. V. Skvortsova, A. E. Rudneva, V. M. Delyagin, Yu. A. Lerkhendorf, G. V. Tereshchenko, D. N. Balashov, M. A. Maschan, A. A. Maschan

    Published 2015-06-01
    “…HSCT complications include the possibility of prolonged immunodeficiency, alloand autoimmune reactions and various organs dysfunction. These conditions require careful monitoring by specialists, early diagnosis and appropriate treatment. …”
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    Article
  10. 4590

    Strength training improves heart function, collagen and strength in rats with heart failure by Leisiane G. Dias, Carlos H. O. Reis, Leonardo dos Santos, Walter Krause Neto, Ana Paula Lima-Leopoldo, Julien S. Baker, André S. Leopoldo, Danilo S. Bocalini

    Published 2024-02-01
    “…Although physical exercise is a well-recognized effective non-pharmacological therapy for cardiovascular diseases, the effects of strength training (ST) on the structural and functional aspects of cardiac remodeling need to be further documented. …”
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    Article
  11. 4591

    Early identification of macrophage activation syndrome in adult-onset Still’s disease: a case report and literature review by Ting Long, Jing Xu, Bo-Zhi Lin, Sheng-Guang Li

    Published 2025-01-01
    “…The application of diagnostic scoring systems like the HScore and MS score is essential for prompt diagnosis and effective treatment, ultimately improving patient survival rates.…”
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    Article
  12. 4592

    Psychometric Properties of the Persian Version of the Frontal Assessment Battery in Patients With Traumatic Brain Injury by Ramin Banimahdi, Seyed Majid Akhavan Hejazi, Seyed Ali Hosseini, Nazila Akbarfahimi, Mohsen Vahedi

    Published 2025-03-01
    “…Conclusion: The P-FAB is a valid, reliable, and effective tool for assessing executive dysfunction in PwTBI.…”
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  13. 4593

    Preclinical Parkinson’s Disease Models for Non-Motor Symptoms: Research Recommendations from a Systematic Review by Mariana Lara Zambetta, Elayne Borges Fernandes, Allison Kim, Thiago Luiz Russo, Anna Carolyna Gianlorenço

    Published 2025-06-01
    “…However, PD is increasingly recognized as a multisystem disorder, where non-motor symptoms such as cognitive impairment, mood disturbances, sleep disorders, and autonomic dysfunction significantly impact patients’ quality of life. …”
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    Article
  14. 4594

    Radiation-induced premature ovarian failure: focus on the role of ovarian inflammatory signaling pathways by Doaa H. Mohamed, Eman M. Mantawy, Riham S. Said, Dina H. Kassem, Amany M. Gad, Ebtehal El-Demerdash

    Published 2023-12-01
    “…Radiation therapy, an effective treatment modality for many types of cancer, often carries a heavy cost for young women. …”
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    Article
  15. 4595

    Atrial Fibrillation in Diabetes: Pathogenesis and Targeted Rhythm Control Strategies by Konstantinos Grigoriou, Paschalis Karakasis, Konstantinos Pamporis, Panagiotis Theofilis, Dimitrios Patoulias, Efstratios Karagiannidis, Barbara Fyntanidou, Antonios P. Antoniadis, Nikolaos Fragakis

    Published 2025-07-01
    “…Conventional rhythm control strategies remain less effective in diabetic individuals, underscoring the need for innovative, substrate-targeted interventions. …”
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    Article
  16. 4596

    Impaired LTB4-induced neutrophil chemotactic directionality in myelodysplastic neoplasms patients by Xinyan Xie, Yumei Liu, Liyan Yang, Zhe Zhang, Hongzhao Li, Wei Zhang, Hong Liu, Huaquan Wang, Zonghong Shao

    Published 2025-12-01
    “…These insights hold significant clinical implications for managing infections in MDS patients, underscoring the importance of targeting specific neutrophil defects for more effective therapeutic strategies.…”
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    Article
  17. 4597

    The Hidden Burden: Gastrointestinal Involvement in Lysosomal Storage Disorders by Vincenza Gragnaniello, Chiara Cazzorla, Daniela Gueraldi, Andrea Puma, Christian Loro, Alberto B. Burlina

    Published 2025-05-01
    “…Results: The pathogenesis of GI involvement in LSDs varies and encompasses substrate accumulation in enterocytes, mesenteric lymphadenopathy, mass effects, smooth muscle dysfunction, vasculopathy, neuropathy, inflammation and alterations to the microbiota. …”
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    Article
  18. 4598

    Surface area outcomes in EUS-guided liver biopsy: a comparative study of Franseen and Fork-tip needles by Kotaro Matsumoto, Shinpei Doi, Takako Adachi, Ayako Watanabe, Nobuhiro Katsukura, Takayuki Tsujikawa, Tatsuya Aso, Mikiko Takahashi, Kentaro Kikuchi

    Published 2025-05-01
    “…Abstract Background The practice of endoscopic ultrasound-guided liver biopsy (EUS-LB) is becoming more common due to its proven safety and effectiveness. For accurate diagnosis, it is vital to secure ample tissue specimens. …”
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    Article
  19. 4599

    Does the hepatologist still need to rely on aminotransferases in clinical practice? A reappraisal of the role of a classic biomarker in the diagnosis and clinical management of chr... by Patrizia Burra, Calogero Cammà, Pietro Invernizzi, Fabio Marra, Maurizio Pompili

    Published 2025-01-01
    “…ALT, a sensitive and cost-effective marker of liver injury, remains pivotal in predicting clinical outcomes and guiding interventions in several chronic liver diseases including metabolic dysfunction-associated steatotic liver disease, and chronic viral hepatitis. …”
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    Article
  20. 4600

    Home nasogastric tube program for NICU infants: a seven year retrospective outcome analysis by Alexa Weninger, Mikayla Sabella, Abe E. Sahmoun, Mohamed W. Mohamed, Mohamed W. Mohamed, Brennan Forward, Brennan Forward, Carrie M. Brower-Breitwieser, Carrie M. Brower-Breitwieser

    Published 2025-04-01
    “…There were no emergency department visits related to feeding tube dysfunction or nasogastric (NG) tube equipment malfunctions. …”
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    Article