Preoperative inflammatory pain exacerbates postoperative pain and neurocognitive impairment by Hui Yuan, Daofan Sun, Bo Lu, Bo Meng, Rongjun Liu, Ruichun Wang, Xiuzhong Xing, Yiqin Ji, Qianyu Ming, Qiusheng Wang, Junping Chen

“…In this study we aimed to clarify the effect of preoperative inflammatory pain on postoperative pain and cognitive function. …”
Get full text

Investigation of the improvement of swallowing function with low-frequency pulse waves or interference waves delivered via cervical electrical stimulation in patients with Parkinso... by Masahiro Nakamori, Ryotaro Matsuyama, Megumi Toko, Hidetada Yamada, Yuki Hayashi, Kohei Yoshikawa, Mineka Yoshikawa, Toshikazu Nagasaki, Yoshitaka Shimizu, Hirofumi Maruyama

“…This randomized controlled trial aims to investigate the effects of cervical electrical stimulation interventions (interferential current or low-frequency pulse wave stimulation) on swallowing dysfunction in patients with PD. …”
Get full text

Depression аnd Cardiovascular Diseases: Cause, Consequence оr Comorbidity by Katerenchuk O.

“…Also the myocardial dysfunction in the form of heart failure is the final link in the chain of cardiovascular continuum. …”
Get full text

Comparative analysis of the efficiency of the use of various types of conduits during coronary artery bypass grafting by L. D. Shengelia, M. O. Konshina, B. Sh. Berdibekov, Z. F. Fatulaev, M. K. Sanakoev, S. A. Donakanyan, K. V. Petrosyan, M. M. Alshibaya, I. Yu. Sigaev, V. Yu. Merzlyakov

“…For example, the incidence of dysfunction of the left internal thoracic artery in the anterior artery basin was 8.2%; the incidence of dysfunction of radial artery in the right artery basin was 12.5 %, and in the obtuse marginal branch basin – 11.5 %; while the incidence of venous conduits’ dysfunction varied, reaching its maximum of 42.8 %.CONCLUSIONS. …”
Get full text

Novel insights into beta cell ER stress CHOP and its role in HFpEF development by Balaji Srinivas, Paula Fortuno, Hongmei Peng, Jiang Xu, Hamid Suhail, Hani N. Sabbah, Nour-Eddine Rhaleb, Khalid Matrougui

“…Abstract Introduction Heart failure with preserved ejection fraction (HFpEF) is a multifactorial cardiovascular disorder characterized by diastolic dysfunction and often associated with hypertension and metabolic disturbances. …”
Get full text

Practical application of the International classification of functioning during medical and social expertise of a child with cerebral palsy by O. V. Nazar, O. V. Hdyria, R. O. Moiseienko, V. Yu. Martyniuk, O. A. Vladymyrov

“…During a comprehensive examination of the child with cerebral palsy, a multidisciplinary team of specialists determined the degree of body dysfunction and limitation in daily life activities as well as environmental effect influence on the level of functioning and social adjustment. …”
Get full text

Neurovascular Restoration by Treadmill Exercise Attenuates Age-Related Cognitive Decline in Mice by Jae Min Lee, Da-Eun Sung, You Jung Choi, Seung Geun Yeo, Youn-Jung Kim

“…Although exercise has demonstrated beneficial effects on aging, its specific impact on age-related microvascular dysfunction and blood-brain barrier (BBB) disruption requires further investigation. …”
Get full text

Comparative ocular outcomes of tirzepatide versus other anti-obesity medications in people with obesity by Yu-Nan Huang, Jo-Ching Chen, Pin-Hung Li, Min-Yen Hsu, Chun-Wen Cheng, Gideon Meyerowitz-Katz, Pen-Hua Su

“…Abstract Background Obesity affects over one billion people worldwide and is associated with ocular complications, yet comparative effects of newer anti-obesity medications on eye health remain poorly understood. …”
Get full text

Clinical Observation of Different Acupuncture Measures on Restoration of Ischemic Stroke Patients'Hand Function by Zheng JIANG, Liping ZHUO, Shaoqin LIAO, Sai'e HUANG

“…After the treatment, the functional connectivity of left M1 with the left precentral gyrus, left postcentral gyrus, the right cerebellum, and right supplementary motor area in TS group were increased; the functional connectivity of left M1 with the left postcentral gyrus, middle frontal gyrus, inferior parietal lobule and supplementary motor area in EA group were increased after treatment;the functional connectivity of left M1 with the left precentral gyrus and postcentral gyrus in MA group were increased, with the left cerebellum was decreased;the functional connectivity of left M1 with the left postcentral gyrus in SA group were increased, but the connection strength was smallest within four groups, and with the left middle frontal gyrus and precentral gyrus was decreased.Conclusion:TS, EA and MA at Quchi and Waiguan can improve upper limb function of IS patients with upper limb dysfunction.rsfMRI study reveals the effect may related to the increase of functional connectivity of left M1 with the precentral gyrus, postcentral gyrus, middle frontal gyrus and supplementary motor area.…”
Get full text

Association between atherosclerosis and the development of multi-organ pathologies by Siarhei A Dabravolski, Alexey V Churov, Natalia V Elizova, Alessio L Ravani, Amina E Karimova, Vasily N Sukhorukov, Alexander N Orekhov

“…As atherosclerosis impacts blood vessels, its adverse effects may manifest across various tissues and organs. …”
Get full text

Endothelial soluble epoxide hydrolase links polyunsaturated fatty acid metabolism to oxidative stress and atherosclerosis progression by Minghua Cao, Mengqing Li, Xixuan Li, Yuanyuan Li, Yunyun Chen, Maria-Kyriaki Drekolia, Xiang Cheng, Fredy Delgado Lagos, Sofia-Iris Bibli, Jiong Hu

Get full text

Fosinopril – a drug of choice in chronic heart failure prevention and treatment by N. Yu. Khosyainova, V. M. Tsareva, O. V. Sukharukova, I. V. Milyagina

“…To study fosinopril effects on clinical status, central hemodynamics, remodeling, LV and RV diastolic filling in patients with chronic heart failure (CHF) and LV systolic dysfunction (LVSD). …”
Get full text

Targeted discovery of gut microbiome-remodeling compounds for the treatment of systemic inflammatory response syndrome by Luyao Liu, Lin Ma, Huan Liu, Fan Zhao, Pu Li, Junhua Zhang, Xin Lü, Xin Zhao, Yanglei Yi

“…The results showed that XFBD administration effectively reduced mortality rates and inflammation in SIRS mice. …”
Get full text

L-Arginine supplementation as mitochondrial therapy in diabetic cardiomyopathy by Antonella Fiordelisi, Federica Andrea Cerasuolo, Roberta Avvisato, Antonietta Buonaiuto, Marianna Maisto, Antonio Bianco, Valeria D’Argenio, Pasquale Mone, Cinzia Perrino, Stefania D’Apice, Roberta Paolillo, Antonio Pezone, Fahimeh Varzideh, Gaetano Santulli, Daniela Sorriento, Guido Iaccarino, Jessica Gambardella

“…Left ventricular hypertrophy, diastolic dysfunction, and exercise intolerance are the first signs of DC. …”
Get full text

Functional Monitoring of Patients With Knee Osteoarthritis Based on Multidimensional Wearable Plantar Pressure Features: Cross-Sectional Study by Junan Xie, Shilin Li, Zhen Song, Lin Shu, Qing Zeng, Guozhi Huang, Yihuan Lin

“… BackgroundPatients with knee osteoarthritis (KOA) often present lower extremity motor dysfunction. However, traditional radiography is a static assessment and cannot achieve long-term dynamic functional monitoring. …”
Get full text

Transanal Irrigation in Patients with Low Anterior Resection Syndrome After Rectal-Sphincter-Preserving Surgery for Oncological and Non-Oncological Disease: A Systematic Review by Andrea Morini, Massimiliano Fabozzi, Magda Zanelli, Francesca Sanguedolce, Andrea Palicelli, Alfredo Annicchiarico, Candida Bonelli, Maurizio Zizzo

“…Background/Objectives: Transanal irrigation (TAI) has been recognized as a safe and effective treatment for neurological bowel dysfunction, chronic constipation or fecal incontinence and has also been proposed for patients with low anterior resection syndrome (LARS). …”
Get full text

RAPTOR: Randomised Controlled Trial of PENTOCLO (pentoxifylline-tocopherol-clodronate) in Mandibular Osteoradionecrosis—study protocol for an open-label phase II randomised control... by Richard Shaw, Ruth Knight, Ayten Basoglu, Mandeep Bajwa, Julie Perry, Anastasios Kanatas, Stefano Fedele, Vincent Killen, Rebecca Tangney, Chris Butterworth, James McCaul, Jagtar Dhanda, Vinod Patel, Mererid Evans, Richard Jackson

“…ORN can cause permanent disfigurement, dysfunction, pain and infection. There remains little robust evidence supporting the efficacy of medical or surgical management currently offered in clinical practice. …”
Get full text

Associations of one-carbon metabolism, related B-vitamins and ApoE genotype with cognitive function in older adults: identification of a novel gene-nutrient interaction by Shane Gordon, Leane Hoey, Helene McNulty, Jordan Keenan, Faith Pangilinan, Lawrence C. Brody, Mary Ward, J. J. Strain, Liadhan McAnena, Adrian McCann, Anne M. Molloy, Conal Cunningham, Kevin McCarroll, Catherine F. Hughes

“…Conclusions Low status of vitamin B12, B6, riboflavin, and/or elevated homocysteine were each associated with a greater risk of cognitive dysfunction. A novel interaction between ApoE ε4 and low B12 or higher homocysteine was associated with an increased risk of cognitive dysfunction. …”
Get full text

Toxic Myocardial Injury in a Patient With Coronary Atherosclerosis, Caused by Acute Poisoning With Gaseous Chlorine by K. G. Alidzhanova, A. Yu. Moiseyeva, A. M. Pashayeva, M. M. Potskhveriya, G. A. Gazaryan, S. Yu. Kambarov

“…Acute chlorine gas poisoning leads to activation of the sympathetic nervous system and, as a consequence, dysfunction of the cardiovascular system (CVS). We report a clinical case of toxic myocardial injury with gaseous  chlorine. …”
Get full text

β-cryptoxanthin suppresses oxidative stress via activation of the Nrf2/HO-1 signaling pathway in diabetic kidney disease by Jingjing Ke, Hualong Zang, Hualong Zang, Yang Liu, Yang Liu, Qiuping Teng, Qiuping Teng, Jiao Hua, Jiao Hua, Dan Peng, Ping Wang, Ping Wang

“…Similarly, in vitro study showed that BCX effectively alleviated the oxidative stress, mitochondrial dysfunction, and senescence induced by HG in podocytes. …”
Get full text