Primary Sjögren’s Syndrome Accompanied by Clinical Features of TAFRO Syndrome by Eiji Suzuki, Takuya Ichimura, Satoru Kimura, Takashi Kanno, Kiyoshi Migita

“…She was diagnosed with SS based on dysfunction of salivary secretion and positivity for anti-Ro/SS-A and La/SS-B antibodies, accompanied by clinical features of TAFRO syndrome based on the presence of anasarca and thrombocytopenia. …”
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Formononetin Exerts Neuroprotection in Parkinson’s Disease via the Activation of the Nrf2 Signaling Pathway by Xiaotong Wang, Nianxin Kang, Ying Liu, Guojie Xu

“…The MPP(+)-induced SH-SY5Y cell PD model was utilized to evaluate the effects of FMN on cell viability, ROS accumulation, and mitochondrial dysfunction. …”
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The role of the neutrophil-to-platelet lymphocyte ratio and the platelet-to-lymphocyte ratio in assessing hypothyroidism Hashimoto’s thyroiditis by Ruqeya Murad, Ayman H. Alfeel, Zulekha Shemote, Praveen Kumar, Asaad Babker, Ahmed Luay Osman, Abdelgdair A. Altoum

“… Hashimoto’s thyroiditis (HT) is the most prevalent autoimmune thyroid disorder, influenced by genetic predispositions, environmental factors, and immune dysfunction. High iodine intake has been identified as a potential trigger in susceptible individuals. …”
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Remote ischaemic preconditioning in cemented hip arthroplasty (the PRINCIPAL study)—randomised controlled trial: study protocol by Jaak Kals, Aare Martson, Kaarel Ernits, Aili Tagoma, Katre Maasalu, Anneli Aus, Kristi Vent, Kaspar Tootsi

“…Introduction Total hip arthroplasty (THA) is an effective treatment for severe osteoarthritis. However, THA has a high surgical risk for patients with concomitant diseases and is associated with several serious complications, such as myocardial infarction, acute kidney injury and cognitive dysfunction. …”
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Clinical efficacy and safety of nerve-sparing radical hysterectomy for cervical cancer: a systematic review and meta-analysis. by Ying Long, De-Sheng Yao, Xin-Wei Pan, Ting-Yu Ou

“…NSRH was also associated with lower bladder dysfunction morbidity and fewer postoperative complications. …”
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Whispers of the polycystic ovary syndrome theater: Directing role of long noncoding RNAs by Xiuying Lin, Xinyu Nie, Ping Deng, Luyao Wang, Cong Hu, Ningyi Jin

“…Polycystic Ovary Syndrome (PCOS) is a multifaceted endocrine disorder that implicates a spectrum of clinical manifestations, including hormonal imbalance, metabolic dysfunction, and even compromised ovarian granulosa cell (GC) activity. …”
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Role of immature granulocytes in monitoring sepsis treatment by Mustafa Deniz, Zahide Sahin Yildirim, Zuleyha Erdin, Murat Alisik, Ridvan Erdin, Mustafa Yildirim

“…Abstract Background Sepsis is an organ dysfunction that impairs response to infection. Inflammatory biomarkers have been used to diagnose and monitor sepsis. …”
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CAMEL MILK; AN ADJUNCTIVE SUPERFOOD FOR DIABETES CASES Tahereh Mohammadabadi by Tahereh Mohammadabadi

“…Camel milk has immune-modulatory effects on the pancreas β-cells. Camel milkinfluences insulin secretion via the proper activity of the pancreatic cells and insulin receptors.Also this special milk improves diabetes complications such as dysfunction in the kidney andliver function and diabetic wounds. …”
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BFGF mitigates CTX-induced ovarian cytotoxicity via SERPINE1/HIF-1 and Nrf-2/HO-1 signaling pathways by Yao Li, Lin Zhang, Hongqing Lv, Chenxuan Mei, Min Hu

“…Additionally, BFGF activated the Nrf-2/HO-1 pathway, boosting cellular defenses against oxidative stress and mitigating mitochondrial dysfunction. Functional studies confirmed that the inhibition of SERPINE1 or BFGF abrogated these protective effects, underscoring the critical roles of these pathways. …”
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Retrospective clinical analysis of adverse drug reactions associated with antiretroviral therapy in Tlokwe district, South Africa by Rentia Van Graan, Michelle Viljoen, Malie Rheeders, Fadeela Motara

“…Various obstacles were identified that influence effective reporting of adverse drug reactions (ADRs) in resource-limited countries. …”
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The dual role of PGAM5 in inflammation by Yuxin Qi, Bhavana Rajbanshi, Ruihan Hao, Yifan Dang, Churong Xu, Wei Lu, Liming Dai, Bingjun Zhang, Xiaoling Zhang

“…Inflammation is strongly correlated with mitochondrial dysfunction. Phosphoglycerate mutase family member 5 (PGAM5) is a novel modulator of mitochondrial homeostasis in response to mechanical stimulation. …”
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Mapping the oxidative landscape in cystic fibrosis: methodological frontiers and application by Michela Rubin, Ilaria Artusi, Ilaria Artusi, Giorgio Cozza, Giorgio Cozza

“…The intricate relationship between CFTR dysfunction, oxidative stress, and inflammation underscores the need to accurately characterize oxidative stress markers to identify therapeutic targets. …”
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Investigating metabolic dysregulation in serum of triple transgenic Alzheimer’s disease male mice: implications for pathogenesis and potential biomarkers by Hongbin Zhuang, Xueshan Cao, Xiaoxiao Tang, Yongdong Zou, Hongbo Yang, Zhiyuan Liang, Xi Yan, Xiaolu Chen, Xingui Feng, Liming Shen

“…Abstract Alzheimer’s disease (AD) is a multifactorial neurodegenerative disease that lacks convenient and accessible peripheral blood diagnostic markers and effective drugs. Metabolic dysfunction is one of AD risk factors, which leaded to alterations of various metabolites in the body. …”
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Mitigating atherosclerosis: Integrating vaccines with gene targets by Alireza Haraj, Masoomeh Bakhshandeh, Nafiseh Shokri, Prand Shariat Rad, Ali Alyan, Zahra Chegini, Mohammad Ali Nazari, Seyed Parsa Seyedi Taji, Mohammad Najafi

“…The formation and progression of atherosclerotic plaques occur through cellular dysfunction and remodeling of the extracellular matrix in the sub-endothelial space of vessels. …”
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Transitional bedside continuous renal replacement therapy for uremic patients after coronary artery bypass grafting by JIANG Xue-yan, HE Yi, YANG Qi, TANG Min, MEI Ju

“…Objective To observe the therapeutic effects of bedside continuous renal replacement therapy(CRRT) after coronary artery bypass grafting(CABG) in uremic patients with coronary heart disease. …”
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Advanced Trans-EEGNet Deep Learning Model for Hypoxic-Ischemic Encephalopathy Severity Grading by Dong-Her Shih, Feng-I Chung, Ting-Wei Wu, Shuo-Yu Huang, Ming-Hung Shih

“…Its clinical manifestations include respiratory distress, cardiac dysfunction, hypotension, muscle weakness, seizures, and coma. …”
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Mesenchymal Stem Cell Therapy for Huntington Disease: A Meta-Analysis by Xue-Song Liang, Zheng-Wu Sun, Aline M. Thomas, Shen Li

“…MSCs transplanted before the occurrence of motor dysfunction rescued the motor incoordination of HD. …”
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MPACT OF PERI-OPERATIVE NORMOVOLEMIC HEMODILUTION ON HEMOSTASIS, BLOOD LOSS AND INDICATIONS TO TRANSFUSION OF DONOR ERYTHROCYTES DURING CARDIAC SURGERY WITH CARDIOPULMONARY BYPASS by N. A. Trekova, D. A. Guskov, B. A. Akselrod, O. V. Dymova, A. V. Gubko, V. G. Gladysheva

“…The analysis of coagulation parameters in the post-perfusion period after modified acute normovolemic hemodilution proved the reduction of hemostasis dysfunction mostly due to the platelet factor.Conclusion. …”
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Dry-printed carbon nanotube film based electrochemical immunosensor for total testosterone detection by Narender Kumar Joon, Jane Besong-Ndika, Elisa Mikkonen, Ville Rajala, Samuel Dulay, Ilkka Varjos

“…Testosterone (TST), a critical hormone for male health, requires precise monitoring due to the significant adverse effects of both deficiency and excess, including reproductive dysfunction, mood alterations, and metabolic imbalances. …”
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Clinical observation of transurethral reconstruction of urethral meatus and navicularis fossa short strictures with annular inlay oral mucosa graft urethroplasty by Zhenyu Li, Zhiguang Zhao, Geng Zhang, He Wang, Bo Zhang, Wei Zhang

“…All patients would recommend urethroplasty to others.ConclusionTransurethral annular inlay oral mucosa urethroplasty for urethral meatus and navicular fossa stricture reconstruction is a safe, feasible, and effective surgical method, cosmetic effect on the penile head. …”
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