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  1. 4261

    Posttranscriptional Regulation of Intestinal Mucosal Growth and Adaptation by Noncoding RNAs in Critical Surgical Disorders by Cassandra A. Cairns, Lan Xiao, Jian-Ying Wang

    Published 2024-01-01
    “…Nonetheless, acute injury and inhibited regeneration of the intestinal epithelium occur commonly in critically ill surgical patients, leading to the translocation of luminal toxic substances and bacteria to the bloodstream. Effective therapies for the preservation of intestinal epithelial integrity and for the prevention of mucosal hemorrhage and gut barrier dysfunction are limited, primarily because of a poor understanding of the mechanisms underlying mucosal disruption. …”
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  2. 4262

    Two strategies for arterial hypertension treatment in patients with secondary chronic pyelonephritis by M. E. Statsenko, M. V. Derevyanchenko

    Published 2011-08-01
    “…In both groups, there was a decrease in the number of patients with circadian BP rhythm disturbances, adverse left ventricular remodelling types, or diastolic dysfunction. The combination of enalapril and indapamide was significantly more effective in terms of restoring renal concentrating function, compared to the combination “enalapril + nifedipine SR”. …”
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  3. 4263

    Melatonin protects rats from radiotherapy-induced small intestine toxicity. by Beatriz Fernández-Gil, Ahmed E Abdel Moneim, Francisco Ortiz, Ying-Qiang Shen, Viviana Soto-Mercado, Miguel Mendivil-Perez, Ana Guerra-Librero, Darío Acuña-Castroviejo, María M Molina-Navarro, José M García-Verdugo, Ramy K A Sayed, Javier Florido, Juan D Luna, Luis Carlos López, Germaine Escames

    Published 2017-01-01
    “…However, despite the prevalence and burden of this pathology, there are currently no effective treatments for radiotherapy-induced gut toxicity, and this pathology remains unclear. …”
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  4. 4264
  5. 4265

    Global inhibition of reactive oxygen species (ROS) inhibits paclitaxel-induced painful peripheral neuropathy. by Mehmet Fidanboylu, Lisa A Griffiths, Sarah J L Flatters

    Published 2011-01-01
    “…Paclitaxel (Taxol®) is a widely used chemotherapeutic agent that has a major dose limiting side-effect of painful peripheral neuropathy. Currently there is no effective therapy for the prevention or treatment of chemotherapy-induced painful peripheral neuropathies. …”
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  6. 4266

    The impact of long COVID on quality of life and work performance among healthcare workers in Portugal by Filipe Prazeres, Ana Paula Romualdo, Inês Campos Pinto, Joana Silva, Andreia M. Oliveira

    Published 2025-03-01
    “…A subgroup of patients experienced long-term effects from the infection, now referred to as long COVID. …”
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  7. 4267

    Dendrobium catenatum Lindl. Water Extracts Attenuate Atherosclerosis by Jichun Han, Jing Dong, Rui Zhang, Xiaofeng Zhang, Minghan Chen, Xiangcheng Fan, Maoru Li, Jiajing Li, Junyi Zhu, Jing Shang, Yunyun Yue

    Published 2021-01-01
    “…Rumor has it that DH has a protective effect against cardiovascular disease. However, it is not clear how DH can prevent cardiovascular disease, such as atherosclerosis (AS). …”
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  8. 4268

    Cholangiographic Features in Opium-Addicted Patients at a Tertiary Hospital in Iran by Amir Houshang Mohammad Alizadeh, Esmaeal Shams Afzali, Azar Sanati, Anahita Shahnazi, Dariush Mirsattari, Mohammad Reza Zali

    Published 2012-01-01
    “…Destructive and metabolic changes in hepatobiliary system have been demonstrated following opium use; however, cholangiographic features of bile ducts in opium-addicted patients with sphincter of Oddi dysfunction are not clearly determined. We described these differences and assessed the effects of opium use on postendoscopic retrograde cholangiopancreatography complications. …”
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  9. 4269

    Early detection of cardiotoxicity in children receiving adriamycin: A comparison of tissue Doppler and standard echocardiography with Troponin I as an early marker. by Mina Farshidgohar, Majid Vafaie, Sonia Oveisi, Maryam Bakhshi

    Published 2025-01-01
    “…However, its most significant adverse effect is cardiac toxicity. Early detection of Adriamycin-induced cardiac dysfunction is crucial in preventing heart failure through interventions such as angiotensin-converting enzyme inhibitors and beta-blockers. …”
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  10. 4270

    Research status of subclinical hypothyroidism promoting the development and progression of cardiovascular diseases by Peijie Wang, Weiming Zhang, Haiyan Liu, Haiyan Liu

    Published 2025-04-01
    “…This review examines the associations between SCH and dyslipidemia, carotid intima-media thickness (C-IMT), cardiac dysfunction, and cardiovascular event risk. Evidence suggests SCH may exacerbate atherosclerosis and cardiac dysfunction through mechanisms such as increased LDL synthesis, oxidative stress, and impaired vascular endothelial function. …”
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  11. 4271

    The relationship between glutathione levels in leukocytes and ocular clinical parameters in glaucoma. by Takeshi Yabana, Kota Sato, Yukihiro Shiga, Noriko Himori, Kazuko Omodaka, Toru Nakazawa

    Published 2019-01-01
    “…<h4>Purpose</h4>To investigate the effect of mitochondrial dysfunction on the autoregulation of blood flow, by measuring levels of glutathione, an indicator of mitochondrial dysfunction, in glaucoma patients.…”
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  12. 4272

    Integration of mitochondrial gene expression and immune landscape in acute kidney injury prediction by Xiaoping Xia, Renyang Liu, Xiaohui Jiang

    Published 2025-12-01
    “…Our findings underscore the critical role of mitochondrial dysfunction and immune modulation in AKI, offering potential avenues for targeted therapeutic strategies.…”
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  13. 4273

    Akt3 links mitochondrial function to the regulation of Aurora B and mitotic fidelity. by Zachary J Hough, Fatemeh Nasehi, Daniel G Corum, Russell A Norris, Ann C Foley, Robin C Muise-Helmericks

    Published 2025-01-01
    “…We used the model oxidant paraquat to induce mitochondrial dysfunction to test whether the Akt3-dependent effect on mitochondrial homeostasis is linked to mitotic function. …”
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  14. 4274

    Ethiopian women’s sexual experiences and coping strategies for sexual problems after gynaecological cancer treatment: a qualitative study by Endalew G Sendo, Gashaw Yada Hundie, Teshome Habte

    Published 2022-03-01
    “…For data analysis, thematic analysis was used, which comprises three stages: data reduction, data display and data conclusion.Results Four themes resulted from the analysis of individual interview data, including treatment side effects, sexual issues following radiation therapy, lack of awareness regarding cancer treatment and sexual dysfunction, and coping strategies for sexual dysfunction following gynaecological cancer treatment. …”
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  15. 4275

    The Impact of Methylphenidate on Sexual Functions: A Systematic Review of Benefits and Risks by Rafał Bieś, Zuzanna Szewczyk, Anna Warchala, Ewa Martyniak, Marek Krzystanek

    Published 2025-05-01
    “…Studies indicate that sexual dysfunction is prevalent among psychiatric patients. …”
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  16. 4276

    Heart rate variability analysis in comorbid insomnia and sleep apnea (COMISA) by Adrián Martín-Montero, Fernando Vaquerizo-Villar, Clara García-Vicente, Gonzalo C. Gutiérrez-Tobal, Thomas Penzel, Roberto Hornero

    Published 2025-05-01
    “…In conclusion, the combined effects of OSA and insomnia induce specific ANS dysfunction at night, highlighting the need for further HRV studies to better understand the impact of COMISA on ANS and its cardiovascular implications. …”
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  17. 4277

    Red yeast rice-induced severe rhabdomyolysis complicated by acute kidney injury and respiratory failure: a case report by Pengmin Zhou, Yucai Hong, Huabo Cai, Xiaoyu Zhou, Shunpeng He, Haotian Zhou, Jie Yang, Pengpeng Chen, Boming Xia, Xiong Lei, Suibi Yang, Zhongheng Zhang

    Published 2025-08-01
    “…Red yeast rice (RYR), a commonly used supplement with statin-like properties, is generally considered safe but may cause severe adverse effects such as rhabdomyolysis. We report a rare case of severe RYR-induced rhabdomyolysis complicated by acute kidney injury (AKI) and respiratory failure, with diaphragmatic dysfunction as a key contributing factor. …”
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  18. 4278

    The association between primary frozen shoulder and serum lipids may be overestimated: evidence based on retrospective observational studies and Mendelian randomization by Yongchao Zhang, Wenhao Fan, Yichang Wang, Tengjing Dong, Deding Liu, Yiming Shao

    Published 2025-01-01
    “…Genetic variants for the serum lipids and frozen shoulder were then extracted from large-scale genome-wide association studies. Causal effects were assessed using Inverse variance weighting (IVW), Weighted median, MR-Egger, simple and weighted models in MR analysis.ResultsThe analysis showed that after excluding patients with diabetes and thyroid dysfunction, the serum lipids (TC, TG, HDL, and LDL) in the primary frozen shoulder group were no different from those of normal individuals. …”
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  19. 4279

    Clinical Research Progress of the Post-Stroke Upper Limb Motor Function Improvement via Transcutaneous Auricular Vagus Nerve Stimulation by Xiaolong Shi, Jingjun Zhao, Shutian Xu, Meng Ren, Yuwei Wu, Xixi Chen, Zhiqing Zhou, Songmei Chen, Yu Huang, Yuanli Li, Chunlei Shan

    Published 2023-01-01
    “…Transcutaneous auricular vagus nerve stimulation (taVNS) is a type of non-invasive stimulation, which can effectively improve post-stroke motor dysfunction. This review discusses stimulation parameters, intervention timing, and the development of innovative devices for taVNS. …”
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  20. 4280

    Role of hypoxia inducible factor pathway in cardiorenal syndrome and application prospect of HIF stabilizer by A Rou-na, He Fang-fang, Sun Xin, Luo Chang-qing

    Published 2022-02-01
    “…It refers to acute or chronic cardiac or renal dysfunction. Its pathophysiology involves immune inflammation,oxidative damage,anemia,iron metabolism disorders,dyslipidemia,hemodynamic disorders,endothelial dysfunction and neurohormonal mechanisms. …”
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