Internet Addiction and Sleep Disorders among Medical Students by Seyyed Mansour Kashfi, Hamed Karami, Fatemeh Jafari, Masumeh Daliri, Maryam Yazdankhah, Amirhossein Kamyab, Ali Khani Jeihooni

“…In addition, there was a significant correlation between Internet addiction and subjective sleep quality (r = 0.191, p = 0.05), sleep latency (r = 0.129, p = 0.01), sleep duration (r = 0.119, p = 0.01), habitual sleep efficiency (r = 0.186, p = 0.05), sleep disturbances (r = 0.169, p = 0.01), use of sleeping medication (r = 0.203, p = 0.05), and daytime dysfunction (r = 0.188, p = 0.05). Conclusion. These findings help national health officials and planners in Iran to design appropriate and effective interventions to improve students’ health and prevent Internet addiction.…”
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Mitochondrial metabolism and cancer therapeutic innovation by Hongxiang Du, Tianhan Xu, Sihui Yu, Sufang Wu, Jiawen Zhang

“…Finally, we discuss the translational challenges in developing effective mitochondria-based cancer interventions.…”
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Pathology and Treatments of Alzheimer’s Disease Based on Considering Changes in Brain Energy Metabolism Due to Type 2 Diabetes by Hidekatsu Yanai, Hiroki Adachi, Mariko Hakoshima, Hisayuki Katsuyama

“…Alzheimer’s disease (AD) is a progressive neurodegenerative disorder with cognitive dysfunction, memory decline, and behavioral disturbance, and it is pathologically characterized by the accumulation of amyloid plaques and neurofibrillary tangles in the brain. …”
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Botulinum toxin treatment of refractory vaginismus: a prospective study by Sejal Ajmera Desai, MD, Bela Shah, MD, George Kroumpouzos, MD, PhD

“…Vaginismus is a common sexual dysfunction. A few studies have indicated that botulinum neurotoxin type A (BoNTA) can help treat refractory vaginismus by alleviating muscle tension. …”
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Advancing Therapeutic Strategies in Atopic Dermatitis: Emerging Targets and Personalized Approaches by Yang Lo, Ting-Ting Cheng, Chi-Jung Huang, Yu-Che Cheng, I-Tsu Chyuan

“…Atopic dermatitis (AD) is a chronic inflammatory skin disorder marked by intricate interplay among skin barrier dysfunction, immune dysregulation, and microbial dysbiosis. …”
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Age-related changes in the immune system and challenges for the development of age-specific vaccines by T. Mark Doherty, Birgit Weinberger, Arnaud Didierlaurent, Paul-Henri Lambert

“…Adjuvants offer a well-established approach to boosting vaccine responses by enhancing innate immunity.Conclusions Of various strategies used to improve immunogenicity of vaccines for older adults, adjuvants have been the most consistently effective and practical. More recently, mRNA vaccines have also shown great promise.…”
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Vaginal Vault Prolapse by Azubuike Uzoma, K. A. Farag

“…Other less commonly performed procedures include uterosacral ligament suspension and illiococcygeal fixation, both of which are equally effective, with the former having a high risk of ureteric injury. …”
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Immune Microenvironment on the Molecular Mechanisms and Therapeutic Targets of MAFLD by Jiang Z, Qian B, Xu T, Bai J, Fu W

“…Despite its widespread impact, treatment options remain limited, and effective therapies targeting the underlying disease mechanisms are lacking. …”
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Immediate and long-term results of microsurgical resection of tentorial meningiomas by R. A. Sultanov, R. S. Dzhindzhikhadze, A. V. Polyakov, V. S. Gadzhiagaev, A. D. Zaitsev, E. I. Salyamova

“…This makes it possible to achieve safe and effective treatment with favorable functional outcomes.…”
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Primary Lymphedema: Anatomically Isolated or a Pervasive Systemic Disorder? by Wei F. Chen, MD, FACS, Christopher Jou, MD, Sonia K. Pandey, MD, Shih-Lun Lo, MD

“…This underscores the importance of comprehensive assessments, even with limited symptoms, to facilitate earlier diagnosis and more effective treatment approaches.…”
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Treatment Challenges in a Tourette Syndrome Patient with Self-Injurious Behaviour: Case Report and Literature Review by G. Asadauskaitė, G. Jasionytė, M. Karnickas

“…The pathogenesis of Tourette syndrome emphasizes the dysfunction of neuronal networks in the basal ganglia. …”
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Recent Advances and Perspectives on the Use of Mineralocorticoid Receptor Antagonists for the Treatment of Hypertension and Chronic Kidney Disease: A Review by Kisho Miyasako, Yujiro Maeoka, Takao Masaki

“…MR antagonists (MRAs) have substantial beneficial effects in patients with cardiac and renal conditions; however, their use has been constrained because of adverse effects, such as hyperkalemia and kidney dysfunction. …”
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Extracorporeal multi-organ support: ECMO, CRRT, and hemoperfusion for acute alcohol intoxication with renal and respiratory failure by Xiting Dang, Shuzhi Lv, Miao Huang, Huini Fu

“…The patient successfully underwent surgical repair for esophageal perforation and showed full recovery at two-year follow-up.Conclusion Integrating CRRT and HP into ECMO circuits offers a novel and effective approach for managing renal dysfunction in acute alcohol intoxication. …”
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Radiological characteristics of shoulder diseases in older adults, including adhesive capsulitis, rotator cuff tear, and osteoarthritis of the glenohumeral joint: a narrative revie... by Myung-Seo Kim, Tae-Hoon Jung

“…This review aims to examine the radiologic findings associated with these shoulder conditions in older patients, providing insights for accurate diagnosis and effective treatment. Adhesive capsulitis, commonly known as frozen shoulder, leads to pain and restricted movement, thereby causing shoulder dysfunction. …”
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Photodynamic therapy for the precise treatment of localized prostate cancer by Youcheng Xu, Qinyuan Tan, Chong Sun, Yuefeng Jia, Shengxian Li, Xuecheng Yang

“…Although PDT is in the early stages of clinical development, it holds promise for the effective treatment of localized prostate cancer. Herein, we reviewed studies on the mechanisms of PDT and photosensitizers for prostate cancer. …”
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Single-Cell Transcriptomic Dataset of RPGR-associated Retinitis Pigmentosa Patient-Derived Retinal Organoids by Ting Li, Yuting Ma, Yun Cheng, Yingke Zhao, Zhixu Qiu, Hongli Liu, Daowei Zhang, Jiawen Wu, Junfeng Li, Shenghai Zhang, Jihong Wu

“…Abstract X-linked retinitis pigmentosa (XLRP) is a severe hereditary retinal disorder marked by progressive vision loss due to photoreceptor dysfunction. The retinitis pigmentosa GTPase regulator (RPGR) gene, responsible for most XLRP cases, encodes a protein crucial for the transport of visual signal proteins between the photoreceptor inner and outer segments. …”
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Postoperative Cognitive Disorder- what do we know about risk factors and prevention? A Systematic Review by Antonina Drzewiecka, Artur Drzewiecki, Wiktor Korczak, Maria Madejska, Aleksandra Rudzka, Monika Gaszyńska, Wojciech Falkowski, Anna Krysińska, Weronika Woźniak, Jakub Magielski

“… Introduction Postoperative Cognitive Dysfunction (POCD) is a significant health complication that affects mental processes, particularly in elderly patients after surgery. …”
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Epigenetic drugs: a new frontier in the treatment of heart failure by K. A. Aitbaev, I. T. Murkamilov, Zh. A. Murkamilova, V. V. Fomin, I. O. Kudaibergenova, T. F. Yusupova, F. A. Yusupov

“…This is especially true in heart failure, where epigenetic mechanisms have been shown to underlie the development of several pathological processes such as left ventricular hypertrophy, fibrosis, cardiomyocyte apoptosis, and microvascular dysfunction. Targeting epigenetic signals may represent a promising approach, especially in patients with heart failure with preserved ejection fraction (HFpEF), where the prognosis remains poor and effective treatments are not yet available. …”
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Precision exosome engineering for enhanced wound healing and scar revision by Chuanqi Liu, Chen Cheng, Kun Cheng, Allen S. Gao, Qingfeng Li, Anthony Atala, Yuanyuan Zhang

“…Abstract The dysfunction of wound-healing processes can result in chronic non-healing wounds and pathological scar formation. …”
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Hearing the call of mitochondria: Insight into its role in sensorineural hearing loss by Haojia He, Zhuoxue Han, Shuai Cheng, You Zhou

“…By integrating current knowledge and identifying key research gaps, this review aims to provide a solid theoretical foundation and fresh perspectives for the development of effective therapeutic strategies for SNHL.…”
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