Transcriptional changes during hepatic ischemia-reperfusion in the rat. by Valerie Zabala, Joan M Boylan, Paul Thevenot, Anderson Frank, Dewahar Senthoor, Varun Iyengar, Hannah Kim, Ari Cohen, Philip A Gruppuso, Jennifer A Sanders

“…There are few effective targeted strategies to reduce hepatic ischemia-reperfusion (IR) injury, a contributor to poor outcomes in liver transplantation recipients. …”
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Antitumour Drug Induced Cardiovascular Toxicity and Current Tumour Treatment Methods by K. S. Gumerova, G. M. Sakhautdinova, I. M. Polyakova

“…While current tumour treatment methods involving drugs such as tyrosine kinase inhibitors, anthracycline chemotherapy and immunotherapy protocols are effective for the treatment of various forms of cancer, these drugs affect the DNA replication process thus resulting in endothelial dysfunction and nonspecific immune response. …”
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Static & dynamic pelvic floor assessment using MR defecography: a radiological prospective observational study with ideal reporting template by Sanket Vinubhai Davra, Anushka Jain, Anurag Kumar

“…Despite limitations like higher costs and the need for patient cooperation, MR defecography offers detailed, dynamic images of the pelvic floor, enhancing diagnostic accuracy and guiding effective treatment strategies. This technique significantly advances pelvic floor dysfunction management, contributing to improved patient outcomes.…”
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Partial Phallectomy and Penile Retroversion as a Surgical Approach for Severe Preputial Laceration in a Donkey (Equus asinus) by Letícia Paranhos Rios Andrade, Helena Tavares Dutra, Jéssyca Ataíde Ferreira, Jéssica Sola Quirino da Silva, Mariana Quinan Bittar, Paulo José Bastos Queiroz

“…Penile trauma in equines can cause injuries of varying severity, potentially leading to temporary or permanent dysfunction. In severe cases, various surgical techniques can be employed to restore the animal’s quality of life, such as partial phallectomy combined with penile retroversion. …”
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FUNCTIONAL STATE OF LEFT VENTRICULAR IN DIFFERENT METHODS OF RESTORATION OF CORONARY BLOOD FLOW IN PATIENTS WITH ACUTE MYOCARDIAL INFARCTION WITH COMPLICATED ACUTE INSUFFICIENCY WI... by A. K. Koyirov, S. R. Kenjaev, S. SH. Khaitov, U. SH. Ganiev, M. S. Mirmaksudov

“…Introduction (goals/objectives): The goal of the study is to compare the indices of contractility and diastolic myocardial dysfunction in patients with acute myocardial infarction complicated by acute cardiac failure after endovascular intervention and thrombolytic therapy.…”
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Dietary intervention with Polygonatum sibiricum polysaccharides mitigates cadmium liver toxicity: a gut-liver axis perspective by Qiannan Di, Huimin Zhou, Huifang Chen, Xiaowei Wang, Xiao Huang

“…PSP decreased Cd accumulation in both the liver and kidney, enhanced intestinal barrier function, promoted the growth of beneficial bacteria (Lactobacillus), and modulated the production of short-chain fatty acids (SCFAs). These effects contribute to the alleviation of Cd-induced hepatic dysfunction and metabolic disorders, including pathways such as riboflavin metabolism, steroid hormone biosynthesis, nucleotide metabolism, purine metabolism, and 2-oxocarboxylic acid metabolism. …”
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PECULIARITIES AND SURGICAL TREATMENT TACTICS OF POSTERO-BASAL LEFT VENTRICULAR ANEURYSMS by V. A. Chragyan, V. B. Arutyunyan, B. K. Kadyraliev, P. A. Mialiuk, A. S. Vronskiy, S. H. Lilothia

“…This applies both to the type of geometric reconstruction of the left ventricle, and the feasibility of mitral regurgitation correction, which due to dysfunction of the papillary muscles is observed in almost all patients with postero-basal aneurysms of the heart. …”
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Safety and Efficacy of NC120 for Improving Lipid Profile: A Double Blind Randomized Controlled Trial by Nafrialdi Nafrialdi, Johannes Hudyono, Frans D Suyatna, Arini Setiawati

“…Background: the use of statin to lower blood cholesterol is often associated with bothersome adverse effects such as myopathy and liver dysfunction. NC120 is herbal lipid lowering drug containing red yeast rice (RYR) extract, guggulipid, and chromium picolinate, and expected to have better safety profile. …”
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Telitacicept as double-targeted therapy for myasthenia gravis coexisting with connective tissue disease: three case reports by Yingying Yang, Yingying Yang, Yingying Yang, Ying Zhu, Ying Zhu, Ying Zhu, Ruixia Zhu, Ruixia Zhu, Ruixia Zhu

“…These findings present preliminary evidence supporting Telitacicept as an effective treatment and a double-target therapy for the management of MG-CTD.…”
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Current Opportunities and Future Prospects of Neuroprotective Therapy in Glaucoma. Literature Review. Part 1 by N. I. Kurysheva, A. V. Korneeva, S. I. Ponomareva, H. M. Plieva, V. E. Kim, I. D. Kim, M. V. Chebotareva

“…A wide range of approaches to neuroprotection demonstrates the great potential for effective treatment of neurodegeneration in order to preserve visual functions in patients with glaucoma.…”
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The role of doxorubicin in the formation of cardiotoxicity is a consensus statement. Part II. Cardiotoxicity of doxorubicin unrelated to myocytes and cardioprotection strategy (rev... by D. A. Andreev, E. I. Balakin, A. S. Samoilov, V. I. Pustovoit

“…The use of doxorubicin in clinical practice has shown cumulative and dose-dependent toxic effects on cardiomyocytes, leading to an increase of mortality risk among patients with cancer and as a resulting to restrictions in the indications for its use.Text. …”
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Lacticaseibacillus rhamnosus Glory LG12 preventives loperamide-induced constipation in mice by modulating intestinal flora and metabolic pathways by Weiwei Ma, Lian Lian, Lidong Guo, Yanan Wu, Lili Huang

“…Studies have shown that probiotics may be effective in relieving constipation by regulating intestinal flora. …”
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Carvedilol: New pharmacological approaches by Mohamed Alaa Hafez, Mona F. Mahmoud, Islam A. A.E.-H. Ibrahim

“…Carvedilol is a non-selective β-blocker with α1-blocking properties which is widely prescribed for treating hypertension, heart failure, and left ventricular dysfunction following myocardial infarction. It has a unique pharmacological profile and acts by several mechanisms of action, making it particularly effective in cardiovascular disorders therapy. …”
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Efficacy of Xuebijing injection on pulmonary ventilation improvement in acute pancreatitis: a systematic review and meta-analysis by Yuling Bin, Rumei Peng, Yaqian Lee, Zhijie Lee, Yang Liu

“…Acute pancreatitis (AP) is induced by localized inflammation, potentially resulting in multiple organ dysfunction syndromes, specifically including acute lung injury (ALI) and acute respiratory distress syndrome (ARDS). …”
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Kinematic analysis of gait in children with rigid flatfoot before and after surgical treatment by Iskandar Yu. Khodjanov, Xasanali I. Umarov, Sherali K. Khakimov, Anvar G. Mirzaev

“…Disease progression also exacerbated pathomorphological changes in the foot, driven by biomechanical dysfunction of the lower leg’s pronator and supinator muscles, alongside reduced gait energy efficiency. …”
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Association of platelet-to-lymphocyte ratio with 1-year all-cause mortality in ICU patients with heart failure by Xinyu Hu, Shijiao Cheng, Huaan Du, Yuehui Yin

“…Abstract The Platelet-to-Lymphocyte Ratio (PLR) has emerged as a cost-effective biomarker for systemic inflammation and adverse cardiovascular outcomes, yet its prognostic value in critically ill patients with heart failure (HF) remains unclear. …”
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Somatic and psychiatric symptoms of brain tumors - a review of the literature by Joanna Olszak, Karolina Zalewa, Dominika Orłowska, Lidia Bartoszek, Wojciech Kapłan, Karol Poleszczuk, Mikołaj Poleszczuk, Alicja Milewska, Anna Czuba

“…Its early detection is crucial as it improves the prognosis of patients, significantly improves their quality of life, and allows for the introduction of effective therapeutic interventions.  …”
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Aquatic therapy for spastic cerebral palsy: a scoping review by Aomeng Xiang, Yanxin Fu, Chengshuo Wang, Dan Huang, Jingman Qi, Ruoxuan Zhao, Liang Wu, Chunliang Fan, Qin Zhang

“…Abstract Background Cerebral palsy (CP) is a group of dysfunction syndrome. Spastic CP is the most common form of CP. …”
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Exploring the innovative application of cerium oxide nanoparticles for addressing oxidative stress in ovarian tissue regeneration by Maya Lakshmanan, Monika Saini, Manasa Nune

“…Abstract The female reproductive system dysfunction considerably affects the overall health of women and children on a global scale. …”
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Modeling of Charcot-Marie-Tooth disease in zebrafish by Małgorzata Korzeniowska née Wiweger, Katarzyna Chabros, Weronika Rzepnikowska, Andrzej Kochański, Dagmara Kabzińska

“…Zebrafish models have been employed to study hallmark features of CMT, including motor deficits, sensory dysfunction, skeletal abnormalities, and auditory neuropathy. …”
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