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  1. 4081

    Endothelial Progenitor Cells for Ischemic Stroke: Update on Basic Research and Application by Shaohua Liao, Chunxia Luo, Bingzhen Cao, Huaiqiang Hu, Suxia Wang, Huili Yue, Lin Chen, Zhenhua Zhou

    Published 2017-01-01
    “…So far, ultra-early thrombolytic therapy is the most effective treatment. However, most patients still live with varying degrees of neurological dysfunction due to its narrow therapeutic time window. …”
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    Article
  2. 4082

    Peculiarities of micronutrient metabolism in obese pregnant women (literature review) by I. A. Zhabchenko, O. R. Sudmak, I. S. Lishchenko, O. M. Bondarenko

    Published 2021-06-01
    “…It is important to consider a woman's body mass index to prescribe the minimum effective dose of the necessary drugs. Timely preventive personalized correction of the micronutrient state can reduce the risks of such major obstetric syndromes as preeclampsia, premature birth, fetal growth retardation, miscarriage, and placental dysfunction.…”
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  3. 4083

    Dimethyl malonate alleviates obstructive nephropathy by enhancing renal metabolism and inhibiting kidney oxidative stress and inflammation by Wei Zhang, Changde Fu, Jinjin Lai, Jun Xin, Wenbin Zhang

    Published 2025-06-01
    “…Succinate dehydrogenase (SDH) is central to mitochondrial metabolism and targeting SDH with dimethyl malonate (DMM) has been shown to be effective in treating renal ischemia-reperfusion (IR) injury in the murine model. …”
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    Article
  4. 4084

    “Super Responder” of Percutaneous Bicaval Valve Implantation for Severe Tricuspid Regurgitation: A Case Report by Ignatius Yansen, Bayushi Eka Putra, Muhammad Yamin, Simon Salim

    Published 2025-01-01
    “…This case underscores the potential utility of the TricValve system in providing an effective, lower-risk treatment option for patients not suited for traditional surgical intervention.…”
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  5. 4085

    Reactive oxygen species in polycystic ovary syndrome: Mechanistic insights into pathogenesis and therapeutic opportunities by Huanju Liu, Lihao Jin, Xiaoya Wang, Junling Shi, Yujie He, Ningxia Sun, Fu Yang

    Published 2025-09-01
    “…By consolidating recent research, this review highlights the profound significance of ROS in PCOS, aiming to inspire innovative pathogenesis research, improve clinical management, and establish a robust theoretical foundation for more effective PCOS treatment strategies.…”
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    Article
  6. 4086

    Comparative gastrointestinal organoid models across species: A Zoobiquity approach for precision medicine by Masaya Tsukamoto, Hidenori Akutsu

    Published 2025-03-01
    “…These models have revolutionized the study of autoimmune disorders, homeostatic dysfunction, and pathogen infections, such as norovirus and Salmonella, which affect millions of humans and animals globally. …”
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  7. 4087

    Nicotinamide Mononucleotide Alleviates Bile Acid Metabolism and Hormonal Dysregulation in Letrozole-Induced PCOS Mice by Caifang Ren, Shuang Zhang, Jianyu Ma, Junjie Huang, Pan Huang, Mingzi Qu, Haoyue Zhao, Zhengrong Zhou, Aihua Gong

    Published 2024-12-01
    “…This study explores the effects of nicotinamide mononucleotide (NMN) in a letrozole-induced PCOS mouse model, focusing on metabolic regulation. …”
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    Article
  8. 4088

    PO72 | Fondaparinux in patient with active tuberculosis

    Published 2025-08-01
    “…Conclusions: the anticoagulation with fondaparinux can be a valid alternative for the treatment of venous thromboembolism in patients on quadruple therapy (isoniazide, ethambutol, rifampin, pyrazinamide) for Mycobacterium tuberculosis infection proving to be safe and effective. …”
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  9. 4089

    Autoantibodies and the Immune Hypothesis in Psychotic Brain Diseases: Challenges and Perspectives by Karrnan Pathmanandavel, Jean Starling, Russell C. Dale, Fabienne Brilot

    Published 2013-01-01
    “…There is a growing body of evidence that points to dysfunction of the immune system in a subgroup of patients with psychosis. …”
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  10. 4090

    Rehabilitation patients of cerebral stroke by L. B. Novikova, K. M. Sharapova

    Published 2024-10-01
    “…Assessment of RP is necessary to develop an effective rehabilitation program and predict the degree of restoration of impaired functions.Objective. …”
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  11. 4091

    Transcranial Doppler Ultrasonography of the Basilar Artery in Cerebral Small Vessel Disease by M. Vikarenko

    Published 2025-04-01
    “…Although it cannot directly visualize small vessels due to limited spatial resolution, it can detect indirect indicators of microvascular dysfunction—most notably elevated pulsatility index (PI) and reduced end-diastolic velocity (EDV), both of which suggest increased distal resistance and impaired perfusion. …”
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  12. 4092

    Design and experimentation of the nested pneumatic soft actuator for hand exoskeleton by Yi Lv, Zaiming Geng, Hao Wu, Yigang He, Zhongming Lv

    Published 2025-08-01
    “…While rigid hand exoskeleton robots are effective, they are often heavy and may cause secondary injuries. …”
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    Article
  13. 4093

    Mitochondrial fusion protein: a new therapeutic target for lung injury diseases by Guiyang Jia, Erqin Song, Qianxia Huang, Miao Chen, Guoyue Liu

    Published 2025-03-01
    “…Regulating mitochondrial fusion, maintaining mitochondrial dynamics, and improving mitochondrial function are effective strategies for mitigating lung tissue and cellular damage. …”
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  14. 4094

    Probiotics Containing Collagen Peptides for Weight Loss and Improvement of Brain Disorders Caused by Obesity in a Mouse Model by Wei-Wen Sung, Tsung-Ming Yeh, Wen-Ling Shih

    Published 2025-01-01
    “…However, the effects of CPP and ORL in female mice were slightly different. …”
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    Article
  15. 4095

    Computer-aided discovery of dual-target compounds for Alzheimer's from ayurvedic medicinal plants. by Mohibullah Shah, Sadia Pervaiz, Iqra Ahmad, Shahid Habib Ansari, Valdir Ferreira De Paula Junior, Sibtain Ahmed, Muhammed Umer Khan, Khaled Fahmi Fawy, Umar Nishan, Hanna Dib, Mohamed A O Abdelfattah

    Published 2025-01-01
    “…Alzheimer's disease (AD) is a neurodegenerative disorder characterized by cognitive decline, driven by the accumulation of amyloid-beta plaques and neurofibrillary tangles. It involves the dysfunction of key enzymes such as Acetylcholinesterase (AChE) and β-secretase (BACE1), making them critical targets for therapeutic intervention. …”
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  16. 4096

    Probable Anti-Glutamate Decarboxylase 65 (Gad65) Antibody-Associated Cerebellar Ataxia. Clinical Case Report and Literature Review by J. Valinčiūtė, P. Petkevičiūtė, R. Balnytė, J. Čiauškaitė

    Published 2023-11-01
    “…As more information about cerebellar ataxia induced by anti- GAD65 antibodies is accumulated, cerebellar dysfunction is increasingly associated with autoimmune causes. …”
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    Article
  17. 4097

    Molecular mechanisms underlying hyperoxia-induced lung fibrosis by I-Ting Chen, Liang-Ti Huang, Chih-Cheng Chen, Chung-Ming Chen

    Published 2022-03-01
    “…Many infants with lung fibrosis develop significant respiratory morbidities including reactive airways dysfunction and obstructive lung disease during childhood. …”
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    Article
  18. 4098

    Genetics of familial amyotrophic lateral sclerosis by A. V. Savinova, N. A. Shnayder, R. F. Nasyrova

    Published 2021-10-01
    “…Information about the genes associated with ALS and understanding of particular pathogenetic mechanisms of the disease play a key role in the development of effective therapeutic strategies.…”
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  19. 4099

    Extracellular Vesicles with Possible Roles in Gut Intestinal Tract Homeostasis and IBD by Xin Chang, Shu-Ling Wang, Sheng-Bing Zhao, Yi-Hai Shi, Peng Pan, Lun Gu, Jun Yao, Zhao-Shen Li, Yu Bai

    Published 2020-01-01
    “…Various studies have found that the dysfunction of intestinal homeostasis contributes to the pathogenesis of inflammatory bowel disease (IBD). …”
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  20. 4100

    Unraveling Vitiligo: From Immune Mechanisms to Promising Therapeutic Strategies by Artur Kovenskiy, Nurlubek Katkenov, Zhussipbek Mukatayev, Almagul Kushugulova

    Published 2024-12-01
    “…Oxidative stress and mitochondrial dysfunction in melanocytes cause vitiligo, while immune privilege protects hair follicle melanocytes, allowing for possible repigmentation. …”
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    Article