Role of Precise Rehabilitation in Diagnosis and Treatment of Consciousness Disorder Caused by Severe Craniocerebral Injury by Yi WU

“…The establishment of precise diagnosis and accurate treatment for DOC patients is a major goal in the development of accurate rehabilitation and a prerequisite for clinical improvement for patients with dysfunction. As the clinical arousing strategy is not yet perfect, more effective evidences are needed, and the standardized treatment, sorting and chronic care for DOC patients have to be more effectively carried out. …”
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Regulation of Senescence in Cancer and Aging by Yahui Kong, Hang Cui, Charusheila Ramkumar, Hong Zhang

“…Senescence is regarded as a physiological response of cells to stress, including telomere dysfunction, aberrant oncogenic activation, DNA damage, and oxidative stress. …”
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Mini-review: Serum immunoglobulins and MASLD by Ke-qian Chen, Wen-jing Cao, Shu-zhi Wang, Wei Li

“…Finding a safe, effective, and economical diagnostic method is essential for the prevention of MASLD. …”
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Induced pluripotent stem cells and derivative photoreceptor precursors as therapeutic cells for retinal degenerations by Rupendra Shrestha, Yao-Tseng Wen, Rong-Kung Tsai

“…Thus, the burden and increased incidence of visual impairment emphasizes the need of novel therapy, where iPSC-derived photoreceptor and RPE cells proved to be promising for curing the retinal dysfunction and act as renovation in approach to improve visual function.…”
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Blonanserin treatment in patients with methamphetamine-induced psychosis comorbid with intellectual disabilities by Okazaki K, Makinodan M, Yamamuro K, Takata T, Kishimoto T

“…Despite the presence of ID in these patients, no significant adverse effects, such as sedation, were detected after treatment with blonanserin.Conclusion: Blonanserin may be an effective and well-tolerated pharmacotherapeutical treatment for patients with MAP comorbid with ID. …”
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PPARδ: A Potential Therapeutic Target for the Treatment of Metabolic Hypertension by Yanli Jiang, Qiang Li, Mengxiao Jia, Zhencheng Yan

“…Multiple metabolic risk factors can cause the vascular dysfunction and vascular lesion, and the hypertension due to metabolic disturbances was defined as metabolic hypertension. …”
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Reduced Glucose Sensation Can Increase the Fitness of Saccharomyces cerevisiae Lacking Mitochondrial DNA. by Emel Akdoğan, Mehmet Tardu, Görkem Garipler, Gülkız Baytek, İ Halil Kavakli, Cory D Dunn

“…Our results highlight the potential importance of nutrient detection and availability on the outcome of mitochondrial dysfunction.…”
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Evaluation of relationships between indicators of the oxidative-antioxidative system and force of respiratory muscles in the case of community-acquired pneumonia by E. P. Kalinina, B. I. Geltser, A. A. Dey, Yu. K. Denisenko, T. P. Novgorodtseva

“…In CAP patients, respiratory muscle dysfunction is associated with imbalanced OAS and the effect of these factors on respiratory muscle contractive activity.…”
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Fabrication of biosynthesized nickel ferrites nanoparticles and evaluation of their insecticidal efficacy on beetles (Blaps polychresta) testicular integrity by Esraa A. Arafat, Abdelazeem S. Eltaweil, Eman M. Abd El-Monaem, Hanan I. Elhenawy, Hussein K. Hussein, Lamia M. El-Samad, Mohamed A. Hassan

“…These results implied that NiFe NPs triggered oxidative injury in the testes, resulting in male reproductive system dysfunction. Altogether, our findings accentuate the potential application of NiFe NPs as nanopesticides, paving the way for the sustainable and cost-effective management of insect pests in agriculture.…”
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Pathogen Detection and Diagnostic Scenarios in Chronic Prostatitis by Vittorio Magri, Gianpaolo Perletti, Konstantinos Stamatiou

“…However, they were more effective in detecting significantly higher percentages of Enterococci. …”
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Cardiotoxicity of Chemotherapeutic Drugs (Literature Review and Clinical Case Description) by Avagimyan Ashot A., Mkrtchyan Lusine G.

“…However, the use of anticancer therapy is limited due to their side effects. In some cases, severe cardiotoxic effects and complications (coronary heart disease, microvascular angina, systolic or diastolic myocardial dysfunction/cardiomyopathy, chronic heart failure, arterial or pulmonary hypertension, strokes, pericarditis, arrhythmias, thromboembolism of the pulmonary artery, etc.), can extremely adversely affect the prognosis of these patients. …”
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Diabetes Mellitus, Cognitive Impairment, and Traditional Chinese Medicine by S. W. Seto, G. Y. Yang, H. Kiat, A. Bensoussan, Y. W. Kwan, D. Chang

“…Despite the therapeutic benefits of antidiabetic agents for the treatment of DM-mediated cognitive dysfunction, most of these pharmaceutical agents are associated with various undesirable side-effects and their long-term benefits are therefore in doubt. …”
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Heartbreak From Gilteritinib: Two Case Reports of Delayed Onset Cardiotoxicity by Kristi Dutta, Ethan D. Kotloff, Manu M. Mysore

“…These cases demonstrate a rare but serious adverse effect of gilteritinib, cardiotoxicity manifested as left ventricular systolic dysfunction, for which more studies are needed to elucidate the underlying pathophysiology.…”
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L-Carnitine: An Antioxidant Remedy for the Survival of Cardiomyocytes under Hyperglycemic Condition by Fernanda Vacante, Pamela Senesi, Anna Montesano, Alice Frigerio, Livio Luzi, Ileana Terruzzi

“…The protective effects of levocarnitine (LC) in patients with ischemic heart disease are related to the attenuation of oxidative stress, but LC mechanisms have yet to be fully understood. …”
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Artificial Intelligence in ECG interpretation - review article by Łukasz Fussek, Jagoda Niewiadomska, Borys Bondos, Aleksandra Stępień, Alicja Paluch, Jakub Skrzypek, Aleksandra Język Polski, Robert Kochan, Ewelina Wieczorek, Kacper Lee

“…This paper aims to show how the development of artificial intelligence can affect more effective interpretation of ECG, thus contributing to greater efficiency for clinicians, and to describe the limitations and potential for further development of artificial intelligence in ECG interpretation.   …”
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Efficacy and safety of voriconazole and caspofungin for the treatment of invasive pulmonary aspergillosis in critically ill patients in China by Zhuo Li, Yuan Zong, Dayu Chen, Juan Ma, Peng Zhang, Lu Cao

“…The two groups were also equally safe in terms of causing renal dysfunction, liver dysfunction, visual abnormalities, and hypokalemia. …”
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Comprehensive Multiomic Analysis Reveals Metabolic Reprogramming Underlying Human Fontan‐Associated Liver Disease by Rasheed Sule, Po Hu, Clarissa Shoffler, Christopher Petucci, Benjamin J. Wilkins, Jack Rychik, Liming Pei

“…Furthermore, comparison with metabolomics data of human metabolic dysfunction–associated fatty liver disease and metabolic dysfunction–associated steatohepatitis highlighted dysregulated amino acid metabolism as a common metabolic abnormality. …”
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Development and validation of a carnitine cycle and transport disorders (CCD) panel: an ONT-compatible multi-gene diagnostic kit for newborn and selective screening by Gökçe Akan, Mehmet Cihan Balcı, Gülten Tuncel, Meryem Karaca, Hasan Hüseyin Kazan, Ahmet Çağlar Özketen, Özge Özgen, Gülden Fatma Gökçay, Fatmahan Atalar

“…Clinically, CCD can manifest with a wide range of symptoms, including hypoketotic hypoglycemia, which may be accompanied by signs of liver dysfunction, hepatic steatosis, myopathy and cardiomyopathy. …”
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Peritoneal Dialysis -Associated Fibrosis: Emerging Mechanisms and Therapeutic Opportunities by Narayan Prasad, Saurabh Chaturvedi, Harshit Singh, Mary Priyanka Udumula, Atul Rawat, Meyyappan Jeyakumar, Akhilesh Jaiswal, Sachin Kumar, Vikas Agarwal

“…Recent approaches to reducing the etiologies of peritoneal membrane dysfunction, the impact of fibroblast switch, and peritoneal membrane events perturbing fibroblast function are explored and suggest using unique, effective therapeutic strategies to target peritoneal fibrosis and associated complications.…”
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Tubular MYDGF Slows Progression of Chronic Kidney Disease by Maintaining Mitochondrial Homeostasis by Xiaohan Liu, Yang Zhang, Youzhao Wang, Yujie Yang, Zhe Qiao, Ping Zhan, Huiying Jin, Qianqian Xu, Wei Tang, Yu Sun, Yan Zhang, Fan Yi, Min Liu

“…Abstract Mitochondrial dysfunction is a key event driving the maladaptive repair of tubular epithelial cells during the transition from acute kidney injury to chronic kidney disease (CKD). …”
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