SUCCESSFUL TREATMENT FOR ATYPICAL HEMOLYTIC UREMIC SYNDROME IN A PUERPERA by O. N. Ulitkina, Zh. S. Filippovskaya, E. I. Prokopenko, A. M. Ovezov, V. V. Likhvantsev

“…., USA) that is a glycosylated humanized monoclonal antibody to immunoglobulins (IgG2/4k) is shown to be effective in treating this disease.Conclusion. Atypical hemolytical-uremic syndrome in pregnancy is a disease, whose treatment difficulties are largely associated with the problem of differential diagnosis with thrombotic thrombocytopenic purpura and man-ifestations of multiple organ dysfunction. …”
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Targeting mitochondria with natural polyphenols for treating Neurodegenerative Diseases: a comprehensive scoping review from oxidative stress perspective by Yueyue Guan, Lei Li, Rui Yang, Yun Lu, Jun Tang

“…Abstract Neurodegenerative diseases are a class of conditions with widespread detrimental impacts, currently lacking effective therapeutic drugs. Recent studies have identified mitochondrial dysfunction and the resultant oxidative stress as crucial contributors to the pathogenesis of neurodegenerative diseases. …”
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Respiratory syncytial viral infection in children. Role in the structure of respiratory pathology and clinical and immunological features by V. V. Sokolovskaya, A. I. Grekova

“…This article is devoted to the analysis of the clinical course of RSV infection in children, the study of the features of the immune status against the background of this disease.It was found that in most cases of RSV infection in children was characterized by signs of bronchial obstruction syndrome and as a consequence in this group of children were found to have dysfunction of the immune system and reduction in the total number of T-lymphocytes, the hyperactivation In-cell component of adaptive immunity, manifested disimmunoglobulinemia (increase in the content of total IgE at lower IgA and IgG), that is, with the formation of immunodeficiency states from T- and B-cell links of adaptive immunity, with long-term recovery of impaired performance, even against the background of effective antiviral therapy.…”
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Peroxisome Proliferator Activated Receptor Ligands as Regulators of Airway Inflammation and Remodelling in Chronic Lung Disease by Jane Elizabeth Ward, Xiahui Tan

“…Anti-inflammatory treatment with corticosteroids is not effective in all patients. Thus, new therapeutic options are required to control diverse cellular functions that are currently not optimally targeted by these drugs in order to inhibit inflammation and its sequelae in lung disease. …”
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Should Albumin Be Used in All Patients with Spontaneous Bacterial Peritonitis? by Neeraj Narula, Keith Tsoi, John K Marshall

“…Patients with cirrhosis who develop spontaneous bacterial peritonitis (SBP) have been reported to experience a high incidence of renal impairment and mortality. Renal dysfunction is possibly related to altered systemic hemodynamics that leads to decreased effective arterial blood volume. …”
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Injection of carbon dioxide instead of iodinated contrast to display the common bile duct during endoscopic retrograde cholangiopancreatography by Cui Liu, Lingyun Tian, Xingyu Ze, Ting Yang, Luowei Wang, Zhaoshen Li

“…Thus, we have demonstrated in this case report that carbon dioxide can be used as a safe, economical, and effective alternative to iodinated contrast agent during ERCP.…”
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IL-13 inhibition in the treatment of atopic dermatitis – new and emerging biologic agents by Carlos Teixeira, Orhan Yilmaz, Diana Bernardo, Tiago Torres

“…This narrative review aims to outline the current state of knowledge regarding the effectiveness and safety of these four biologic agents targeting IL-13 signaling.…”
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Research progress on AMPK in the pathogenesis and treatment of MASLD by Jiang Feng, Li MengHuan, Yao TingTing, Yi XueJie, Gao HaiNing

“…A deeper understanding of AMPK regulatory mechanisms will contribute to the development of more effective therapeutic approaches for MASLD.…”
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A Review: Neurotoxicity of Doxorubicin by Hanan Saadon, Noor Abd Alkhudhur Salman

“…This neurotoxicity can lead to various neurological complications, including cognitive impairments, neuropathic pain, and motor dysfunction. The neurotoxic effects of Doxorubicin are attributed to several mechanisms, including oxidative stress, inflammation, neuroinflammation and apoptosis of neuronal cells. …”
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Unraveling the cardiorenal metabolic syndrome: A deep dive into the Indian population’s health crisis by Niladri Dingal

“…Cardiorenal metabolic syndrome (CRMS) is emerging as a health crisis in the Indian population, marked by the interplay of cardiovascular disease, renal dysfunction, and metabolic disorders. This study delves into the multifaceted nature of CRMS, highlighting its rising prevalence driven by lifestyle changes, urbanization, and dietary habits. …”
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Research progress in comorbidity between epilepsy and sleep disorders by Luyao HUANG, Jing DING, Xin WANG

“…Epilepsy, which leads to an enduring high tendency to generate epileptic seizures, is a neurological disorder characterized by recurrent episodes of paroxysmal brain dysfunction due to abnormal synchronous neuronal discharges. …”
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Inositol Treatment and ART Outcomes in Women with PCOS by Deepika Garg, Reshef Tal

“…It is the most common cause of infertility secondary to ovulatory dysfunction. The underlying etiology is still unknown but is believed to be multifactorial. …”
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Treatment of facial lipodystrophy induced by a biologic agent (IPD-1): a literature review by Henri Friedhofer, Cristina Pires Camargo, Leandro Hirokazu Oshiro, Daniel de Almeida Rocha Valente, Rolf Gemperli

“…We treated the facial lipodystrophy with autologous fat grafting, which proved to be effective for more than three years. This study showed the efficacy of IPD-1 lipodystrophy treatment with long-term follow-up.…”
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Pathways to Aging: The Mitochondrion at the Intersection of Biological and Psychosocial Sciences by Martin Picard

“…Both chronic exposure to psychosocial stress and genetic-based mitochondrial dysfunction have strikingly similar biological consequences; both predispose individuals to adverse age-related health disorders and early mortality. …”
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Quality of Life in Arthritis Patients Using Nonsteroidal Anti-Inflammatory Drugs by Ingela Wiklund

“…The degree of distress and dysfunction differed markedly from scores in an unselected population. …”
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The Role of MicroRNAs in the Pathogenesis of Diabetic Nephropathy by Jian Tang, Deyi Yao, Haiying Yan, Xing Chen, Linjia Wang, Huakui Zhan

“…Diabetic nephropathy (DN) is one of the most common microvascular complications in diabetic patients; it is also an important cause of renal dysfunction, renal fibrosis, and end-stage renal disease. …”
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EXPERIENCE WITH IN ON-X PROSTHESIS IN HEART VALVE REPLACEMENT by M. A. Sazonenkov, D. A. Basarab, S. S. Krivorot, M. N. Korneluk

“…The prosthesis ON-X carcas has advantages in implantation commodity and safety, effective orifice area. We pe- sent results of this prosthesis usage during perioud of 2006–2009 years. …”
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Occlusal indicators for irreversible occlusal therapy: A narrative review by Preeti Chawla Arora, Aman Arora, Raghunath Patil, Shilpi Gilra

“…Any dental procedure can alter occlusal proportions, and even minor discrepancies, such as high spots, may lead to dysfunction. Effective occlusal therapy aims to reduce stress on the masticatory system to prevent adverse effects. …”
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Naringenin impairs mitochondrial function via ROS to induce apoptosis in tamoxifen resistant MCF-7 breast cancer cells. by Lauren A Eanes, Mayar Eldeeb, Darrell Storholt, Yashomati M Patel

“…While tamoxifen, a commonly used drug therapy in breast cancer patients, is effective, many patients acquire tamoxifen resistance. …”
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Trichotillomania as a Manifestation of Dementia by Pongsatorn Paholpak, Mario F. Mendez

“…This patient and a review of the literature suggest that trichotillomania may be a compulsive-related symptom in dementias of different etiologies as they involve frontal areas and release primitive grooming behavior from frontostriatal dysfunction. Dopamine blockade, rather than SSRIs, may be effective in managing trichotillomania in dementia.…”
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