Suggested Topics within your search.
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3581
The use of antimuscarinics, phosphodiesterase type V inhibitors and phytotherapy for lower urinary tract symptoms in men
Published 2017-07-01“…Many patients with LUTS also have erectile dysfunction, and phosphodiesterase type V inhibitors are effective in relieving both LUTS as well as erectile dysfunction for such patients. …”
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3582
Probiotics in Depression Management: Efficacy, Mechanisms and Future Directions
Published 2025-01-01“…Furthermore, the long-term effects of probiotic use with antidepressants, their role in reducing antidepressant side effects, and combined effects with psychotherapy are largely understudied. …”
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3583
Statin Therapy and Cognitive Impairment: Benefit or Harm?
Published 2018-09-01“…Evaluation of cognitive dysfunction in patients before starting therapy with statins is not necessary. …”
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3584
The role of BRCA status on the prognosis of patients with epithelial ovarian cancer: a systematic review of the literature with a meta-analysis.
Published 2014-01-01“…<h4>Conclusions</h4>Patients with BRCA dysfunction status tend to have a better outcome, but further prospective clinical studies comparing the different BRCA statuses in EOC is urgently needed to specifically define the most effective treatment for the separate patient groups.…”
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3585
The Cellular and Molecular Biology of Aging
Published 2024-01-01“…This article provides insight into specific biological mechanisms associated with aging, such as genomic instability, telomere dysfunction, epigenetic modifications, and mitochondrial dysfunction. …”
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3586
Emerging Role of SH3BP2 as Regulator of Immune and Nonimmune Cells in Nephrotic Syndrome
Published 2024-11-01“…MCD and FSGS have distinct but also overlapping clinical, histological, metabolic, and molecular features. Effective use of immunosuppressive drugs, activated immune cells, altered cytokine profiles, and upregulated signaling pathways suggest a link between immune dysfunction and nephrotic syndrome, but the exact mechanism of immunopathogenesis is unclear. …”
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3587
Evaluation of the Relationship between Backpain, Headache, Obstructive Sleep Apnea, and their Referred Pain Pattern in Patients with TMJ Disorders - A Case-Control Study
Published 2025-04-01“…Background: Temporomandibular disorder (TMD) is a condition which includes pain and dysfunction in the masticatory muscles and temporomandibular joints (TMJ). …”
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3588
A New Clinical Entity Bridging the Cardiovascular System and the Kidney: The Chronic Cardiovascular-Kidney Disorder
Published 2025-01-01“…Key Messages: (i) The CCKD concept calls for simplification and conceptual clarity, arguing that understanding the bidirectional acceleration of disease progression between heart and kidney dysfunction can lead to more effective treatment strategies. …”
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3589
Lactate and pyruvate as inborn errors of metabolism screening markers and their analytical challenges—a review
Published 2025-06-01“…Inborn errors of metabolism (IEM) is a heterogeneous group of disorders resulting in metabolic dysfunction leading to the build-up of abnormal metabolite or energy deficiency. …”
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3590
Somato-Regulatory Imbalance as a Pathophysiological Basis of Civilization Diseases
Published 2025-08-01“…Understanding the complex pathophysiological mechanisms underlying these conditions is critical for developing effective prevention and treatment strategies. Aim This study aims to investigate the interconnected pathways linking metabolic dysfunction, endothelial dysfunction, and cardiovascular complications, with a particular emphasis on the role of advanced glycation end-products (AGEs), reactive oxygen species (ROS), and dysregulation of the autonomic nervous system (ANS). …”
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3591
Interstitial fluid transport in linea alba is involved in acupuncture-induced attenuation of ovarian hypofunction in aged rats
Published 2025-05-01“…Although acupuncture at conception vessel acupoints is an effective therapeutic approach for managing ovarian dysfunction, the biological underpinnings bridging peripheral stimulation to systemic endocrine regulation remain elusive. …”
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3592
Research progress on ocular rosacea
Published 2025-05-01“…Ocular rosacea shares a similar pathogenesis with cutaneous rosacea, involving immune responses, neurovascular dysfunction, and alterations in the ocular microbiome, which contribute to inflammation and meibomian gland dysfunction. …”
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3593
Pathophysiology, noninvasive diagnostics and emerging personalized treatments for metabolic associated liver diseases
Published 2025-08-01“…Abstract Metabolic Dysfunction-Associated Steatohepatitis (MASH), the advanced stage of Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD), is a leading cause of chronic liver disease, driving cirrhosis, liver cancer, and mortality. …”
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3594
Late Presentation of Cauda Equina Syndrome with Isolated Bladder Bowel Incontinence in Massive Lower Lumbar Disc Herniation: A Series of Three Cases
Published 2025-02-01“…Thus, surgical decompression of massive lumbar disc prolapse can be done in the initial stages of bladder-bowel dysfunction. Surgical decompression is effective in delayed presentation of CES with good long-term prognosis.…”
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3595
A mathematical model for active contraction in healthy and failing myocytes and left ventricles.
Published 2017-01-01“…Cardiovascular disease is one of the leading causes of death worldwide, in particular myocardial dysfunction, which may lead to heart failure eventually. …”
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3596
Clinical outcomes of the tunica albuginea plication for patients with Peyronie’s disease: a bicentric retrospective analysis
Published 2025-05-01“…Postoperative satisfaction was reported by 67% of patients. Erectile dysfunction developed in 16%, and 13% experienced complications. …”
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3597
Liver quad culture chip as a model for radiation injury research
Published 2025-04-01“…We observed metabolic dysfunction, inflammation, endothelial dysfunction, and HSCs activation. …”
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3598
Post-viral olfactory loss and parosmia
Published 2023-10-01“…The emergence of SARS-CoV-2 has brought olfactory dysfunction to the forefront of public awareness, because up to half of infected individuals could develop olfactory dysfunction. …”
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3599
Transvertebral magnetic neuromodulation for the treatment of overactive bladder: 6 months follow-up
Published 2020-12-01“…The most common type of lower urinary tract dysfunction is an overactive bladder (OAB). Today there is a need to search for new effective methods of treating this disease.Purpose of the study. …”
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3600
Obesity and Pulmonary Hypertension: A Review of Pathophysiologic Mechanisms
Published 2012-01-01“…Novel mechanisms of PH in the obese include endothelial dysfunction and hyperuricemia. A wide range of effective therapies exist to mitigate the disability of PH in the obese.…”
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