Effects of the different intensities of task-oriented training on the upper extremity motor function and self-care ability of stroke survivors: study protocol for a multiarm parall... by Kai Zhang, Chunxiang Li, Shengfeng Liu, Xuecha Li, Mengsi Peng

“…Therefore, this study aims to explore the effects of different intensities of TOT on motor function and self-care ability of stroke survivors.Methods and analysis This randomised controlled clinical trial will recruit 72 participants from a tertiary hospital, diagnosed with decreased self-care ability and upper limb motor dysfunction post-stroke. …”
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Effects of an extended therapeutic strategy versus standard-of-care therapy on persistent acute kidney injury in high-risk patients after major surgery: study protocol for the rand... by Joachim Gerss, Melanie Meersch, Carola Wempe, Alexander Zarbock, John Kellum, Christian Strauss, Thilo von Groote, Mahan Sadjadi, Hendrik Booke, Ludwig Maximilian Schöne, Leonie Sauermann

“…The key secondary endpoint is the composite of death, initiation of renal replacement therapy within 90 or persistent renal dysfunction at day 90.Ethics and dissemination The PrevProgAKI trial has been approved by the Ethics Committee of the Chamber of Physicians Westfalen-Lippe and the University of Muenster (no. 2021-569 f-S). …”
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[Comment] Effect of denonvilliers’fascia preservation versus resection dur ing laparoscopic total mesorectal excision on postoperative urogenital function of male rectal cancer pat... by Ye Xiaolong

“…[Background] The protective effect of DVF during L-TME on pelvic autonomic nerves and postoperative urogenital function remains controversial. …”
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The Effect of a Single Temporomandibular Joint Soft Tissue Therapy on Cervical Spine Mobility, Temporomandibular Joint Mobility, Foot Load Distribution, and Body Balance in Women w... by Iwona Sulowska-Daszyk, Paulina Handzlik-Waszkiewicz, Sara Gamrot

“…In contemporary times, a significant portion of the population experiences symptoms of temporomandibular joint (TMJ) dysfunction. The objective of this study was to evaluate the effects of a single-session TMJ soft tissue therapy on the TMJ and cervical spine mobility as well as on body balance and the foot load distribution. …”
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Impact of baseline left ventricular ejection fraction and body mass index on the effect of 24-week Ipragliflozin treatment on left ventricular diastolic function in patients with t... by Hiroki Teragawa, Atsushi Tanaka, Kanae Takahashi, Chikage Oshita, Yuko Uchimura, Nozomu Kamei, Hiroyuki Hirai, Michio Shimabukuro, Isao Taguchi, Yosuke Okada, Koichi Node

“…In this sub-analysis of the Program of Ipragliflozin for Endothelial Dysfunction in Chronic Kidney Disease and Type 2 Diabetes (PROCEED) trial—including patients with type 2 diabetes mellitus (T2DM) and chronic kidney disease (CKD)—we examined the effect of ipragliflozin compared with non-SGLT2 inhibitor standard therapy (control) on changes in the maximum early diastolic velocity to average early diastolic peak velocity (E/e’) ratio (an index of LV diastolic function) via echocardiography. …”
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Mesenchymal stem cells reduce the genotoxic effect of lead acetate in the testis of male rats and induce testicular cellular proliferation indicated by 16S rRNA sequence, increase... by Mohamed Allam, Yahia A. Amin, Samer S. Fouad, Rana A. Ali, Mariam A. Fawy, Maha Abd-El Baki Ahmed, Rana Toghan, Lobna A. Ali

“…Conclusions It can be concluded that the MSCs are a potential therapeutic for the treatment of testicular dysfunction induced by LA through the reduction of oxidative stress, genotoxic effect, and apoptosis marker caspase-3, and an increase in the proliferation marker Ki-67 in the testicular tissue associated with restoration of hormonal imbalance.…”
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Local cell therapy using CCL19-expressing allogeneic mesenchymal stem cells exerts robust antitumor effects by accumulating CD103+ IL-12-producing dendritic cells and priming CD8+... by Yuichi Iida, Mamoru Harada

“…This local cell therapy could be a promising approach to anticancer therapy, particularly for overcoming dysfunction in the cancer-immunity cycle.…”
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Possibilities of rehabilitation of the psychological state of children over 10 years old, suffering from acute respiratory diseases, in conditions of war in Ukraine by I.O. Mityuryayeva-Kornijko, Ie.A. Burlaka, T.D. Klets, O.A. Panchenko, A.V. Kabantseva, R.V. Terletskiy

“…Modern psychophysiological studies confirm that chronic stress leads to dysfunction of the autonomic nervous system, endocrine disorders and, as a result, somatic diseases. …”
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Therapy of chronic heart failure in patients with hypersensitivity pneumonitis and coronary heart disease by A. V. Medvedev, G. E. Alichubanova, N. G. Dem'yanenko, S. A. Kasimtseva, M. N. Kovalevskaya, R. V. Tarasov

“…Objective: to study the effect of enalapril and valsartan + sacubitril on the reduction of CHF symptoms, on the change in functional and radiological parameters in patients with hypersensitivity pneumonitis (HP) combined with coronary heart disease. …”
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Effect of auricular acupoint massage combined with auricular acupoint pressing in nursing of patients with insomnia of heart and spleen deficiency type (耳穴按摩操联合耳穴压丸缓解心脾两虚型失眠效果观察)... by LI Chunhong (李春红)

“…Objective To observe the effect of auricular acupoint massage combined with auricular acupoint pressing in nursing of patients with insomnia of heart and spleen deficiency type. …”
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Clinical and Laboratory Features, Treatment and Prognosis in Children with Guillian-Barre Syndrome by N. A. Suponeva, A. K. Shakaryan, A. V. Rakhteenko, M. A. Piradov, I. V. Mitrofanova, M. I. Prytkova, I. Ya. Leont’ieva, S. V. Shakhgildyan, N. S. Morozova

“…The treatment has shown to be effective for the majority of patients, but three children was resistant to the intravenous immunoglobulin. …”
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The content of some vasoactive humoral-metabolic factors in patients with cirrhosis and their participation in pathogenesis of comorbid syntropical damages of cardiovascular system by Abrahamovych M., Abrahamovych О., Farmaha M.

Subjects: “…the most probable pathogenetic chains are endothelial dysfunction…”
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Individual oral hygiene and microscopic assessment of the structure bristle toothbrushes in their daily use

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The impact of carnosine on myosin for a possible intervention or prevention of systolic heart failure by Kim, N.

“…Thus, it is paramount to develop a more effective therapeutic treatment by specifically targeting the carnosine protein. …”
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Expert perspectives on the use of safinamide for Parkinson’s disease in Portugal: insights from a Portuguese Delphi Consensus by Ana Margarida Rodrigues, Cristina Costa, Miguel Gago, Miguel Grunho, Leonor Correia Guedes, Ana Morgadinho, Maria Jose Rosas, Rita Simoes, Ana Graca Velon

“…Additionally, agreement was reached on its positive effects on nonmotor symptoms such as sleep, fatigue, mood, quality of life and pain management. …”

Subacute thyroiditis in pregnancy: a narrative review by Mahmoud Ali Kaykhaei, Zahra Heidari

“…In its painful form, subacute thyroiditis may lead to severe disability, with systemic glucocorticoids being the best effective treatment option. When painless, the condition often comes to medical attention due to thyroid dysfunction. …”
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MICROCIRCULATORY ISCHEMIA AND STATINS: LESSONS OF INTERVENTION CARDIOLOGY by An. A. Alexandrov, I. I. Tchukaeva

“…In coronary patients after transluminal angioplasty microcirculatory dysfunction is the reason of phenomenon of “non-reflow”. …”
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Innovative therapeutic strategies using ADHD medications tailored to the behavioral characteristics of patients with chronic pain by Satoshi Kasahara, Satoshi Kasahara, Miwako Takahashi, Takashi Suto, Taito Morita, Hideaki Obata, Shin-Ichi Niwa

“…Beyond typical ADHD medications like central stimulants, norepinephrine reuptake inhibitors, and alpha-2 receptor agonists, various antidepressants, mood stabilizers, antipsychotics, Parkinson’s disease medications, and antidementia medications have proven effective in alleviating ADHD symptoms. These medications, effective for ADHD, may offer innovative solutions for managing chronic pain by targeting both the cognitive/behavioral dysfunction and central sensitization observed in chronic pain comorbid with ADHD. …”
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Hepatocardiorenal Syndrome: Integrating Pathophysiology with Clinical Decision-Making via Point-Of-Care Ultrasound by Abhilash Koratala, Claudio Ronco, Amir Kazory

“…Recent understanding reveals how cardiac dysfunction plays a pivotal role in the development of renal dysfunction in this setting, suggesting that disturbances traditionally categorized under hepatorenal syndrome may actually represent a hepatic form of cardiorenal syndrome – hepatocardiorenal syndrome – where the liver affects the kidney through cardiorenal pathways. …”
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