PCSK9-antibodies fail to block PCSK9-induced inflammation in macrophages and cannot recapitulate protective effects of PCSK9-deficiency in experimental myocardial infarction by Simon Rauterberg, Simon Rauterberg, Carmen Härdtner, Jennifer Hein, Paola Schrepf, Remi Peyronnet, Christoph Koentges, Tamara A. Vico, Carolin Ehlert, Bianca Dufner, Diana Lindner, Constantin von zur Mühlen, Dennis Wolf, Dirk Westermann, Ingo Hilgendorf, Alexander von Ehr

“…Alirocumab treatment, while effective in lowering plasma cholesterol, did not replicate the survival benefits seen in PCSK9 KO mice and even worsened cardiac function post-MI. …”
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Effects of repetitive transcranial magnetic stimulation combined with repetitive peripheral magnetic stimulation on upper limb motor function after stroke: a systematic review and... by Shanshan Luo, Zhu Wen, Ying Liu, Tao Sun, Li Xu, Qian Yu

“…ObjectiveTo evaluate the effectiveness of repetitive transcranial magnetic stimulation (rTMS) combined with repetitive peripheral magnetic stimulation (rPMS) on upper limb motor dysfunction after stroke.MethodsWe systematically searched databases up to May 2024, including PubMed, Embase, Cochrane Library, Web of Science, CNKI, VIP, Wanfang, and CBM. …”
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Comparison of the effectiveness of mindfulness-based stress reduction versus cognitive-behavioral therapy on emotion regulation, mindfulness, and cognitive-executive functions in f... by Emad Alkasir, Abbas Masjedi-Arani, Fatemeh Jafarian Dehkordi, Amir Sam Kianimoghadam, Behrooz Afshari, Shafigheh Yousefi

“…BACKGROUND: Rheumatoid arthritis affects physical and mental health; it brings psychological consequences such as dysfunctions in emotion regulation and cognitive-executive functions. …”
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The adverse effect of metabolic syndrome on left ventricular global strains and myocardial energetic efficiency in non-ischemic dilated cardiomyopathy patients: a cardiac magnetic... by Meng-Ting Shen, Yuan Li, Ke Shi, Jin Wang, Li Jiang, Yu Jiang, Yue Gao, Shi-Qin Yu, Xue-Ming Li, Wei-Feng Yan, Zhi-Gang Yang

“…This study aimed to investigate the effect of MetS on LV dysfunction in NIDCM patients using cardiovascular magnetic resonance (CMR) imaging. …”
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Effect of experimental gestational diabetes and administration of glibenclamide on mRNA level of NLRP3-inflammasome and distribution of NLRP3+-cells in mesenteric lymph nodes in pr... by Т. М. Prozorova, V. A. Kamyshna, О. М. Kamyshnyi

“…A number of dysfunctions of congenital and adaptive components of the immune system are observed in progeny of rats with experimental gestational diabetes (EGD). …”
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Neuroprotective Effects of ZiBuPiYin Recipe on db/db Mice via PI3K-Akt Signaling Pathway by Activating Grb2 by Wei-ming Ren, Ze-bin Weng, Xin Li, Li-bin Zhan

“…Diabetes-associated cognitive decline (DACD) is one of the nervous system dysfunctions induced by diabetes mellitus with cognitive impairment as the major symptom. …”
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Comparative effects of xylitol and erythritol on modulating blood glucose; inducing insulin secretion; reducing dyslipidemia and redox imbalance in a type 2 diabetes rat model by Nontokozo Z. Msomi, Ochuko L. Erukainure, Veronica F. Salau, Kolawole A. Olofinsan, Md. Shahidul Islam

“…Xylitol and erythritol have been reported in numerous previous and recent studies as potential antidiabetic sweeteners, however, it is not certain which one is most effective in this regard. In the present study, the effects of xylitol and erythritol were comparatively investigated on blood glucose, insulin level, dyslipidemia, pancreatic islet morphology and β-cell function, and redox imbalance in a type 2 diabetes (T2D) model of rats. …”
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Ameliorative Effects of some Natural Antioxidants against Blood and Cardiovascular Toxicity of Oral Subchronic Exposure to Silicon Dioxide, Aluminum Oxide, or Zinc Oxide Nanopartic... by Riyadh Musaed Naji, Mohamed A. Bashandy, Abdallah H. Fathy

“…In conclusion, the administration of FOD provides considerable chemopreventive and ameliorative effects against NP toxicity.…”
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Effects of transcranial direct current stimulation combined with acupuncture therapy on brain network functional connectivity in patients with knee osteoarthritis: a single-center... by Qiu Nie, Fang He, Linghui Dong, Xikai Lin, Jingyi Lin, Yinxu Wang, Yulei Xie

“…Abstract Background In this study, we investigated the effects of transcranial direct current stimulation (tDCS) combined with acupuncture therapy on pain, dysfunction and functional connectivity in patients with knee osteoarthritis (KOA), and to evaluate its potential therapeutic value. …”
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Independent and combined relationships between light at night, air pollutants, PM2.5 components and risk of cardiovascular-kidney-metabolic syndrome: a cohort study by Ziyue Liang, Siyu Qing, Yifang Liang, Renfang Zhang, Mengyao Sun, Ziyu Ren, Chunejie Xu, Fei Lin, Yongbin Wang

“…Abstract Background Cardiovascular-kidney-metabolic (CKM) syndrome, characterized by interconnected cardiovascular, renal, and metabolic dysfunctions, poses a growing global health burden. While both light at night (LAN) and air pollutants have independently been linked to adverse health outcomes, their synergistic and joint effects on CKM syndrome risk remain poorly understood. …”
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SMOKING AS A RISK FACTOR OF CARDIOVASCULAR AND CEREBROVASCULAR DISEASES: PREVALENCE, IMPACT ON PROGNOSIS, POSSIBLE SMOKING CESSATION STRATEGIES AND THEIR EFFECTIVENESS. Part 1. Smo... by O. D. Ostroumova, A. A. Izvekov, N. Yu. Voevodina

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Effects of sub-lethal copper sulfate exposure on blood parameters and metabolic enzymes activity in Prussian carp, Carassius auratus from river of Shatt Al-Arab, Iraq by Aseel Al-Salman

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Effects of switching from stavudine to raltegravir on subcutaneous adipose tissue in HIV-infected patients with HIV/HAART-associated lipodystrophy syndrome (HALS). A clinical and m... by Pere Domingo, María del Mar Gutierrez, José Miguel Gallego-Escuredo, Ferran Torres, Gracia María Mateo, Joan Villarroya, Ignacio de los Santos, Joan Carles Domingo, Francesc Villarroya, Luis Del Rio, Vicente Estrada, Marta Giralt

“…HIV-1/HAART-associated lipodystrophy syndrome (HALS) has been associated with exposure to stavudine (d4T) through mitochondrial dysfunction. We performed a 48-week study to assess the effects of switching from d4T to raltegravir (RAL) on metabolic and fat molecular parameters of patients with HALS. …”
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The independent and interactive effects of heavy metal pollution and vitamin D deficiency on early kidney injury indicators: analysis of the National Health and Nutrition Examinati... by Shuhui Jing, Yuan Ge, Juan Pan, Pei Chang, Xi Qiao

“…Furthermore, we conducted an interaction analysis to assess the combined effects of heavy metal exposure and vitamin D deficiency on early kidney injury. …”
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Mediating effect of fasting blood glucose and peripheral arterial disease on the relationship between sexual functioning and health-related quality of life among Nigerians with typ... by Olufemi O. Oyewole, Ayotunde O. Ale, Ayanbola I. Adepoju, Grace M. Emmanuel, Michael O. Ogunlana, Olufunmilayo O. Oyewole, Olatunde Odusan

“…Abstract Background Poor glycemic control and sexual dysfunction have been shown to impair health-related quality of life (HRQoL) of individuals with diabetes. …”
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Shen-Qi-Jie-Yu-Fang exerts effects on a rat model of postpartum depression by regulating inflammatory cytokines and CD4+CD25+ regulatory T cells by Li J, Zhao R, Li X, Sun W, Qu M, Tang Q, Yang X, Zhang S

“…Aim: To further investigate the effect of SJF on the immune system, including the inflammatory response system and CD4+CD25+ regulatory T (Treg) cells. …”
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Causal effect of three autoimmune diseases on brain functional networks and cerebrospinal fluid metabolites to underlie the pathogenesis of autoimmune psychosis: a two-sample mende... by Weiman Shi, Min Chen, Rongai Wang, Chengping Wen, Lin Huang, Qiao Wang

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Effects of body weight-supported Tai Chi Yunshou training on upper limb motor function in stroke patients: A three-arm parallel randomized controlled trial. by Liying Zhang, Xiaoming Yu, Wangsheng Liao, Jiening Wang, Yan Lu, Naizhen Wang, Zhou Huanxia

“…<h4>Objectives</h4>To form a unique body weight support-Tai Chi Yunshou (BWS-TCY) training method, apply it to the treatment of upper limb dysfunction after stroke, and provide a new safe and effective treatment method for the clinic.…”
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Effects and mechanisms of acupuncture for PIGD-subtype Parkinson’s disease via integration of fMRI and gut microbiota-metabolomics analysis: protocol for a prospective randomized c... by Jili Sheng, Jili Sheng, Yingqi Xu, Tao Liu, Jianfang Zhu, Caiyun Mu, Lihao Zhai, Shanhu Xu, Hanyi Wang, Xiangzhi Liu, Tao Liu, Xiaoqing Jin

“…IntroductionParkinson’s disease (PD) can be categorized into various subtypes based on the primary symptoms associated with motor dysfunction. One subtype, known as postural instability and gait difficulty (PIGD), is characterized by severe clinical symptoms, an increased risk of walking difficulties and falls, and a poorer prognosis compared to other subtypes. …”
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Effectiveness and Safety of Hair Growth Formulation Containing L.f (Teak) Leaf Extract: A Randomized, Double-Blind, Placebo-Controlled Study on Males with Androgenic Alopecia by Nutchaninad Tanuphol B.ATM, Neti Waranuch PhD, Vanuchawan Wisuitiprot PhD, Wudtichai Wisuitiprot PhD, Kamonlak Insumrong PhD, Prapapan Temkitthawon PhD, Nungruthai Suphrom PhD, Katechan Jampachaisri PhD, Corine Girard PhD, Kornkanok Ingkaninan PhD

“…Furthermore, the HT-teak group reported the highest satisfaction scores, and there were no indications of skin irritation or systemic effects on sexual dysfunction and palpitation after 24 weeks of HT-teak application. …”
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