CENTRAL HEMODYNAMICS IN ELDERLY PATIENTS WITH CHRONIC HEART FAILURE: THE EFFECTS OF COMPLEX TREATMENT INCLUDING PERINDOPRIL/INDAPAMIDE AND LOW-INTENSITY LASER THERAPY by T. V. Filippova, Yu. A. Mel’nikova, G. G. Efremushkin

“…To assess and compare the effects of perindopril/indapamide (Noliprel) and low-intensity laser therapy (LILT) on central hemodynamic parameters in elderly patients with chronic heart failure (CHF). …”
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Effects of acute pro-inflammatory stimulation and 25-hydroxycholesterol on hippocampal plasticity and learning involve NLRP3 inflammasome and cellular stress responses by Yukitoshi Izumi, Kazuko A. O’Dell, Steven Mennerick, Charles F. Zorumski

“…Abstract Neuroinflammation is an increasingly important target for therapeutics in neuropsychiatry and contributes to cognitive dysfunction, disability and death across a range of illnesses. …”
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Comparative effects of renin-angiotensin-aldosterone system modulators on right heart function and prognosis in patients with severe systolic chronic heart failure by K. G. Adamyan, L. R. Tumasyan, A. L. Chilingaryan

“…Aim. To compare the effects of renin-angiotensin-aldosterone system (RAAS) modulators in patients with severe chronic heart failure (CHF). …”
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COMPARATIVE ANALYSIS OF THE EFFECT OF NATURAL SUGAR AND STEVIA ON THE BIOCHEMICAL PARAMETERS, BLOOD PROFILE, MDA, AND BODY WEIGHT OF RABBITS FROM NEW ZEALAND by I. D. Saleh, M. A. Shahooth, F. T. Al-Rawi

“…This study compared the metabolic effects of stevia versus natural sugar in New Zealand White rabbits (n=30) over 30 days. …”
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Effect of acute exposure of lead acetates on the morphology of liver and kidney of mice (Mus musculus) and the role of vitamin C as a repairing agent by Ishraq J. H, Wissam S.H. Al-Uboody, M.A. Al-Diwan

“…The objective of this study is to elicit the destructive effect of lead on the tissues of liver and kidney of mice and if vitamin C is capable of repairing the damage caused by lead. …”
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Effects of small sided football and date seed (Phoenix dactylifera) powder supplementation on liver enzymes in inactive college subjects: an interventional study by Mohammad Mehdi Khaleghi, Abdossaleh Zar, Hamid Reza Sadeghipour

“…Purpose In recent years, the rising prevalence of metabolic disorders and liver dysfunction due to sedentary lifestyles and poor nutrition has become a growing health concern. …”
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Long-term effectiveness and safety of risankizumab in patients with moderate-to-severe psoriasis with and without cardiometabolic comorbidities: a single-center retrospective study by Luciano Ibba, Sara Di Giulio, Luigi Gargiulo, Paola Facheris, Chiara Perugini, Antonio Costanzo, Alessandra Narcisi, Mario Valenti

“…Background: Psoriasis is a chronic skin disease driven by immune system dysfunction and associated with increased cardiovascular risk and metabolic disorders. …”
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NMR Metabolomic Profiling of Differentiated SH-SY5Y Neuronal Cells: Amyloid-β Toxicity and Protective Effects of Galantamine and Lycorine by Arian Kola, Filippo Costanti, Jordan Kahfi, Abdul-Hamid Emwas, Mariusz Jaremko, Daniela Valensin

“…Both GAL and LYC contributed to the restoration of glutamine and lysine homeostasis, but LYC had a more pronounced effect, better sustaining cellular energy balance and mitochondrial function. …”
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Effects of pioglitazone on mnemonic hippocampal function: A blood oxygen level–dependent functional magnetic resonance imaging study in elderly adults by Annchen R. Knodt, James R. Burke, Kathleen A. Welsh‐Bohmer, Brenda L. Plassman, Daniel K. Burns, Stephen K. Brannan, Michael Kukulka, Jingtao Wu, Ahmad R. Hariri

“…Abstract Introduction Mitochondrial dysfunction is implicated in the pathophysiology of Alzheimer's disease (AD). …”
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Identifying iNOS and glycogen as biomarkers for degenerated cerebellar purkinje cells in autism spectrum disorder: Protective effects of erythropoietin and zinc sulfate. by Abdulaziz M Al-Garni, Sara A Hosny, Faris Almasabi, Ayed A Shati, Norah M Alzamil, Asmaa M ShamsEldeen, Asmaa A El-Shafei, Fahaid Al-Hashem, Hind Zafrah, Amro Maarouf, Bahjat Al-Ani, Ismaeel Bin-Jaliah, Samaa S Kamar

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Effectiveness of deep electroacupuncture with strong deqi and shallow electroacupuncture with no deqi for lumbar disk herniation: study protocol for a randomised controlled trial by Ziling Huang, Jianxin Zhao, Xinghong Pei, Bobo Wang

“…Introduction Lumbar disk herniation (LDH) is a common cause of low back pain and dysfunction. Studies have shown that electroacupuncture (EA) can achieve pain relief in patients with LDH. …”
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Effectiveness of Ultrasonographic Unilateral Dual Transversus Abdominis Plane Block in Pain Control in Pediatric Renal Transplantation: A Randomized Controlled Trial by Sherif M. Soaida, Heba M. Nassar, Ahmed Hazem, Pierre Zarif Tawadros, Hany A. Morsi, Ahmed I. Shoukry, Ahmed M. Shouman, Fatina I. Fadel, Hafez M. Bazaraa, Doaa M. Salah, Mohamed A. Abdel Mawla, Dina A. Salah, Mohamed A. Selim

“…Background: Effective postoperative pain control in pediatric kidney transplant recipients is essential but poses challenges due to the limitations of systemic opioid use in patients with renal dysfunction. …”
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Vasoprotective Effects of Hyperoside against Cerebral Ischemia/Reperfusion Injury in Rats: Activation of Large-Conductance Ca2+-Activated K+ Channels by Wen-Ming Hong, Yue-Wu Xie, Meng-Yu Zhao, Tian-Hang Yu, Li-Na Wang, Wan-Yan Xu, Shen Gao, Hua-Bao Cai, Yan Guo, Fang Zhang

“…The results showed that Hyp significantly reduced infarct volume and ameliorated neurological dysfunction in I/R-injured rats. Besides, the effects of I/R-induced reduction of BK channels α- and β1-subunits expression were significantly reversed by Hyp in endothelial-denudated cerebral basilar arteries. …”
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Effect of Periodic Granulocyte Colony-Stimulating Factor Administration on Endothelial Progenitor Cells and Different Monocyte Subsets in Pediatric Patients with Muscular Dystrophi... by Andrzej Eljaszewicz, Dorota Sienkiewicz, Kamil Grubczak, Bożena Okurowska-Zawada, Grażyna Paszko-Patej, Paula Miklasz, Paulina Singh, Urszula Radzikowska, Wojciech Kulak, Marcin Moniuszko

“…Muscular dystrophies (MD) are heterogeneous group of diseases characterized by progressive muscle dysfunction. There is a large body of evidence indicating that angiogenesis is impaired in muscles of MD patients. …”
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Deciphering the Structural and Functional Effects of the R1150W Non-Synonymous Variant in SCN9A Linked to Altered Pain Perception by Faisal A. Al-Allaf, Zainularifeen Abduljaleel, Mohammad Athar

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Freeze-dried herbal Kaempferia galanga supplementation effectively modulates hyperglycemia-induced oxidative stress and apoptosis in diabetic BALB/c mice by Flavius Phrangsngi Nonglang, Revelbornstar Snaitang, Dhritiman Roy, Surya Bhan

“…Abstract Background A dysfunction in insulin secretion or action leads to hyperglycemia. …”
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Ameliorative Effect of <i>Artemisia absinthium</i> Ethanolic Extract Against Sodium Fluoride Toxicity in Rat Testes: Histological and Physiological Study by Sawsan A. Ali, Zainab A. H. AL-Mousawi, Ahlam A. AL-Rikaby, Sameh Mohamed Farouk, Shaaban S. Elnesr

“…This study aimed to investigate the effect of <i>Artemisia absinthium</i> extract on testicular dysfunction in rats and explain the involvement of the androgen receptor signaling pathway as a biomarker in maintaining fertility during sodium fluoride (NaF) treatment. …”
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A PI3K Inhibitor with Low Cardiotoxicity and Its Synergistic Inhibitory Effect with Gilteritinib in Acute Myelogenous Leukemia (AML) Cells by Tianze Wu, Yi Chen, Yimin Gong, Mingzhu Lu, Chengbin Yang, Yannan Yang, Yun Ling, Yaming Zhou

“…FD274 demonstrated lower adverse effects associated with cardiac dysfunction, oxidative stress, and myocardial injury in the C57BL/6 mouse model and in the H9C2 cell line as compared with FD268. …”
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Pathway of effects of adverse childhood experiences on psychological distress and substance use among emerging adults: A structural equation modeling approach by Ajith K. Remesan, Varalakshmi Chandra Sekaran, Satyanarayana Poojari, Teddy Andrews Jaihind Jothikaran, Vani Lakshmi R, Lena Ashok

“…Background: Adverse childhood experiences (ACEs) refer to various types of abuse, neglect, and household dysfunction that individuals may experience in childhood. …”
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The effect of pro-inflammatory cytokines on the development of atherosclerosis in systemic lupus erythematosus patients: ultrasonographic assessment of intimal medial thickness and... by Mohamed Nasser, Mary Wadie, Alyaa Farid, Azza El Amir

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