Potential Effect of Human Platelet Lysate on in vitro Expansion of Human Corneal Endothelial Cells Compared with Y-27632 ROCK Inhibitor by Mohammad Amir Mishan, Sahar Balagholi, Tahereh Chamani, Sepehr Feizi, Zahra-Soheila Soheili, Mozhgan Rezaei Kanavi

“…Abstract Purpose: Corneal endothelial cell (CEC) therapy can be used as a promising therapeutic option for patients with various corneal endothelial dysfunctions. In this study, we compared the proliferative effect of human platelet lysate (HPL), as a xeno-free medium supplement, with Y-27632 Rho/rho-associated protein kinase (ROCK) inhibitor, as a well-known proliferative and adhesive agent for CECs, and fetal bovine serum (FBS) as the control, in the culture medium of human corneal endothelial cells (HCECs). …”
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Aryl hydrocarbon receptor signaling in male fertility: Protective role of resveratrol and disruptive effects of CH223191 in adult male rats by Ghadeer Sabah Bustani, Hasan Falah Kashef Alghetaa

“…These findings suggest the therapeutic potential of AhR-targeting agents like RES in ameliorating male reproductive dysfunctions associated with oxidative stress and xenobiotic exposure.…”
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Salvia aristata Essential Oil: Chemical Composition, Cholinesterase Inhibition, and Neuroprotective Effects against Oxidative Stress in PC12 Cells by Farid Dabaghian, Shokoufeh Aalinezhad, Mohammad Reza Delnavazi, Mina Saeedi, Mahnaz Khanavi*

“…Background and objectives: The cholinergic system plays a crucial role in CNS modulation, where dysfunctions are linked to cognitive and motor impairments. …”
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Effect of glycemic status on myocardial deformation and microvascular function in uncomplicated pediatric type 1 diabetes mellitus: cardiac magnetic resonance imaging by Lu Zhang, Shan Huang, Xueming Li, Zhi Yang, Pengfei Ye, Ran Sun, Huayan Xu, Rong Xu, Meng Zhang, Ying Liu, Chuanjie Yuan, Jin Wu, Yingkun Guo

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Effects of lumbar joint mobilization on trunk control, balance, and gait in patients with stroke: study protocol for a randomized controlled trial by Can Chen, Bo Yan, Shan He, Ruidi Wu, XiaoHua Han, Yong Chen, Hong Chen, Lingfeng Xie

“…Abstract Background After stroke, most patients have impairments in trunk control, balance, and gait. These dysfunctions are closely related to the ability to perform activities of daily living. …”
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Effect of Renal and Left Ventricular Function on Serial Pulmonary Arterial Pressure Changes after Device Closure of Atrial Septal Defect by Chul Shin, Young Won Yoon, In-Soo Kim, Jong-Youn Kim, Pil-Ki Min, Byoung Kwon Lee, Bum-Kee Hong, Se-Joong Rim, Hyuck Moon Kwon, Eui-Young Choi

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Effects of an 8-Week Abdominal Hypopressive Technique Program on Pelvic Floor Muscle Contractility: An Assessor-Blinded Randomized Controlled Trial by Olga López-Torres, Miriam Álvarez-Sáez, Jorge Lorenzo Calvo, Loreto Carmona, Lidón Soriano

“…Background: Pelvic floor muscle (PFM) dysfunctions, such as urinary incontinence (UI), significantly impact women’s quality of life. …”
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Differential inflammation, oxidative stress and cardiovascular damage markers of nano- and micro-particle exposure in mice: Implications for human disease burden by Marin Kuntic, Ivana Kuntic, Dirk Cleppien, Andrea Pozzer, David Nußbaum, Matthias Oelze, Tristan Junglas, Lea Strohm, Henning Ubbens, Steffen Daub, Maria Teresa Bayo Jimenez, Sven Danckwardt, Thomas Berkemeier, Omar Hahad, Matthias Kohl, Sebastian Steven, Albrecht Stroh, Jos Lelieveld, Thomas Münzel, Andreas Daiber

“…We investigated the varying effects of particle size on specific organ systems using a custom mouse exposure system and synthetic PM (SPM). …”
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Restraint stress effects on glutamate signaling protein levels in the rats’ frontal cortex: Does β1 adrenoceptor activity matter? by Agnieszka Zelek-Molik, Anna Gądek-Michalska, Michał Wilczkowski, Adam Bielawski, Katarzyna Maziarz, Grzegorz Kreiner, Irena Nalepa

“…IntroductionStress-evoked dysfunctions of the frontal cortex (FC) are correlated with changes in the functioning of the glutamatergic system, and evidence demonstrates that noradrenergic transmission is an important regulator of this process. …”
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The effect of a complex of melatonin, aluminum oxide and polymethylsiloxane on the cellular composition of the mice spleen kept in round-the-clock lighting conditions by A. V. Shurlygina, S. V. Michurina, L. N. Rachkovskaya, A. E. Serykh, S. M. Miroshnichenko, E. E. Rachkovsky, M. A. Korolev, A. Yu. Letyagin

“…In this regard, it is relevant to search for opportunities to restore disturbed circadian rhythms and, especially, to correct immune dysfunctions that occur in these situations.The aim of this study was to examine the effect of a complex of melatonin, aluminum oxide and polymethylsiloxane on the lymphocytes of the spleen of mice kept under round-the-clock lighting.Materials and methods. …”
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Aerobic-Resistance Training with Royal Jelly Supplementation Has a Synergistic Effect on Paraoxonase 1 Changes and Liver Function in Women with MASLD by Roya Askari, Nazanin Rabani, Hamid Marefati, Marzie Sadat Azarnive, Matteo Pusceddu, Gian Mario Migliaccio

“…Therefore, the aim of this research is to investigate and compare the effects of aerobic-resistance training with royal jelly supplementation on changes in paraoxonase 1, oxidized LDL, liver function, and lipid profile in postmenopausal women with Dysfunction-Associated Steatotic Liver Disease. …”
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Hepatotoxic Effects of Gaseous Sulfur Dioxide (SO₂), Nitrogen Dioxide (NO₂), and Their Mixture on Sea Bass (Centropristis striata): Hematological, Biochemical and Genotoxic Studies... by N. Gandhi, Y. Rama Govinda Reddy and Ch. Vijaya

“…Significant declines in albumin levels, indicating potential liver dysfunction or inflammation due to SO2 and NO2 exposures, were observed at all experimental conditions, while decreased globulin levels suggest immunosuppressive effects from combined pollutants. …”
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Effect of dapagliflozin on serum N‐terminal fragment-proB‐type natriuretic peptide level in patient with acute decompensated heart failure by Hanna Jassim Dohei, Maitham Ali Al-Rikabi

“…It can arise from various conditions that impact ventricular filling (diastolic dysfunction) or myocardial contractility (systolic dysfunction). …”
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Effects of Esketamine Versus Remifentanil on Hemodynamics and Prognosis in Patients with Septic Shock Receiving Invasive Mechanical Ventilation: A Randomized Controlled Trial by Li Y, Li H, Zhang F, Chen Y, Zhang D

“…Secondary outcomes included mechanical ventilation time(hours), dosage of propofol (mg/kg), intestinal dysfunction rate, ICU length of stay(days), hospital length of stay(days), hospital mortality and 28-day survival rate. …”
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EFFECTIVENESS OF PHARMACOTHERAPY FOR NORMALIZATION OF THE BRAIN NATRIURETIC PEPTIDE, RENINE-ANGIOTENSINALDOSTERONE SYSTEM ACTIVATION AFTER SURGICAL REVASCULARIZATION OF MYOCARDIUM... by S. A. Kovalev, V. Е. Malikov, V. Yu. Merzlyakov, A. A. Bulynin, A. В. Bulynin, E. A. Krasyukova, E. V. Malyutin, М. А. Arzumanyan

“…In the controlled, randomized study of 103 CHD patients with severe systolic dysfunction of the LV, the effectiveness  of aortic  coronary  bypass  surgery  was  studied.  …”
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Curcumin Analog J7 Attenuates Liver Fibrosis and Metabolic Dysregulation in a Rat Model of Type 2 Diabetes via Modulation of TGF-β/Smad and NF-κB/BCL-2/BAX Pathways by Ma J, Chen W, Vaishnani DK, Wang C, Xue S, Yang Q, Tong Y, Lei N, Zhao Z, Ying F

“…This study highlights the potential of improving natural compounds like curcumin to make them more effective as medicines. Further research is needed to explore how J7 might help people with diabetes and liver issues.Keywords: insulin resistance, metabolic dysfunction-associated fatty liver disease, MAFLD, curcumin analog, liver fibrosis, TGF-β/Smad signaling pathway, NF-κB-BCL-2/BAX axis…”
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Effect of Yoga and Naturopathy Intervention on Neuropathic Pain in a Patient Suffering from Diabetic Peripheral Neuropathy: A Clinical Case Report by S Indiradevi, S Prashanth, G Sathiyavathi

“…The beneficial effects of yoga and naturopathy on diabetes are well established. …”
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CO40 | The co-inheritance of two ITGB3 variants exerting additive detrimental effects on platelets leads to variant Glanzmann thrombasthenia

“…Dominant gain-of-function (GOF) variants in ITGA2B or ITGB3 cause macrothrombocytopenia with platelet dysfunction. The co-inheritance of two heterozygous αIIbβ3 gene variants with different impact on integrin function is a rare event whose final effect on platelet function is hardly predictable. …”
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A prospective clinical study to evaluate the comparative effectiveness of dry needling and laser therapy in neck and upper back myofascial pain syndrome by Sevinç Külekçioğlu

“…Introduction: Myofascial pain syndrome (MPS) is a disorder of the musculoskeletal system that is distinguished by the presence of pain, tenderness, muscle spasms, restricted joint range of motion, fatigue, and, in rare cases, autonomic dysfunction. Aim: The purpose of this study was to compare the effectiveness of laser and dry needling (DN) treatments for enhancing cervical joint range of motion, neck pain, and quality of life in patients with active upper trapezius myofascial trigger points who experience persistent neck pain. …”
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Synergistic Effects of Low-Frequency Ultrasound and Therapeutic Agents on Endothelial and Renal Cells: Emphasis on Cell Functionality, Oxidative Stress, and Inflammatory Markers by Ieva Čiapienė, Joris Vėžys, Vaiva Lesauskaitė, Indrė Matulevičiūtė, Ugnė Meškauskaitė, Vilius Skipskis, Arvydas Strazdauskas, Sonata Trumbeckaitė, Algimantas Bubulis, Vytautas Jūrėnas, Vytautas Ostaševičius, Vytenis Tamakauskas, Vacis Tatarūnas

“…Endothelial dysfunction contributes to CMD, impairing vascular tone and increasing inflammation. …”
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