Immediate Effects of Uphill Treadmill Walking Exercise on Ankle Dorsiflexion Range of Motion and Torque in Patients With Limited Ankle Dorsiflexion by Sejong Park, Yixin Wang, Beom-Seop Kim, Hye-Seon Jeon

“…Objects: This study aimed to examine the immediate effects of a 15° UTWE on DF ROM and torque generation in patients with limited DF. …”

A Comparative Analysis of Effects of Rehabilitation Services on Symptomatology of Parkinson’s Disease-An Umbrella Review of Systematic Reviews and Meta-Analyses by Zobia Farooq, Rayan Aboakel, Rabeaa Sahar, Zareen Akhtar, Tahira Irshad, Jennifer Geller

“…Non-motor symptoms are effectively treated with cognitive therapies and pharmacological treatments such as SSRIs, benzodiazepines, and antidepressants. …”
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Evaluation of the Cognitive-Behavioral, Anti-Inflammatory, Antioxidant, and Neuroprotective Effects of Hydroxytyrosol on the Hippocampus in a PTZ-Induced Kindling Model by Milad Ansari, Fatemeh Gholami, Kimia Foroutan Jahromi, Alireza Dolatizadeh, Mohammad Amin Edalatmanesh*

“…Background and objectives: Cognitive-behavioral impairments and neurological dysfunctions are commonly investigated in animal models of epilepsy. …”
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Polyphenols, Alkaloids, and Terpenoids Against Neurodegeneration: Evaluating the Neuroprotective Effects of Phytocompounds Through a Comprehensive Review of the Current Evidence by Enzo Pereira de Lima, Lucas Fornari Laurindo, Vitor Cavallari Strozze Catharin, Rosa Direito, Masaru Tanaka, Iris Jasmin Santos German, Caroline Barbalho Lamas, Elen Landgraf Guiguer, Adriano Cressoni Araújo, Adriana Maria Ragassi Fiorini, Sandra Maria Barbalho

“…Conventional treatments for neurodegenerative conditions incur high costs and are related to the development of several adverse effects. In addition, many patients are irresponsive to them. …”
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Adverse effects of remdesivir, hydroxychloroquine and lopinavir/ritonavir when used for COVID-19: systematic review and meta-analysis of randomised trials by Long Ge, Bram Rochwerg, Dena Zeraatkar, Anila Qasim, Thomas Agoritsas, Ariel Izcovich, Reem A Mustafa, Assem M Khamis, Derek K Chu, Romina Brignardello-Petersen, Elena Kum, Shelley L McLeod, Reed Alexander Siemieniuk, Per Vandvik, Jessica Julia Bartoszko

“…Remdesivir may have no important effect on risk of acute kidney injury or cognitive dysfunction/delirium. …”
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Effects of pyruvate administration on mRNA expression of inflammatory cytokines in adipose tissue and whole‐body glucose metabolism in male mice by Taichi Ando, Reo Takeda, Ryotaro Kano, Tatsuya Kusano, Yudai Nonaka, Yutaka Kano, Daisuke Hoshino

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Comparison of Anticancer Effects of Histone Deacetylase Inhibitors CG-745 and Suberoylanilide Hydroxamic Acid in Non-small Cell Lung Cancer by Hyo Jin Kim, Ui Ri An, Han Jee Yoon, Hyun Lim, Ki Eun Hwang, Young Suk Kim, Hak Ryul Kim

“…Consequently, we demonstrated the therapeutic efficacy of the novel HDAC inhibitor, CG-745, in comparison with existing inhibitors such as suberoylanilide hydroxamic acid (SAHA) in non-small cell lung cancer (NSCLC) cells. Methods CG-745's effect on apoptosis and reactive oxygen species (ROS)-dependent mitochondrial dysfunction was investigated using annexin V assay, MitoSoX, and Western blot in human A549 and H460 cells. …”
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Effect of isavuconazole on the concentration of tacrolimus in a patient with genotype CYP3A5*1/*3: a case report by Hayato Yokota, Yumiko Akamine, Harumi Hatakeyama, Hideaki Kagaya, Sho Sakamoto, Mitsuru Saito, Masahide Takeda, Kazuhiro Sato, Katsutoshi Nakayama, Masafumi Kikuchi

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Effects of propofol on the cognition and hippocampal N-methyl-D-aspartate subunits expression in an MPTP-induced Parkinson’s disease rat model by Ping Zhu, Yongyan Zhang, Hua Xu, Yu Ren

“…The imbalance of hippocampal N-methyl-D-aspartate (NMDA) receptors NR2A/NR2B subunit ratio is reported to be associated with memory dysfunction in PD rats. The current study investigated the effects of propofol on the cognitive function and hippocampal NR2A/NR2B ratio in a 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced PD rat model.MethodsMPTP was stereotaxically injected into the substantia nigra pars compacta of male Wistar rats. …”
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The effectiveness of dual-task exercises in individuals with chronic obstructive pulmonary disease: a study protocol for a randomized controlled trial by Begüm Ünlü, Aysel Yıldız Özer, İpek Özmen, Mine Gülden Polat

“…Studies examining the effect of cognitive dysfunction evaluated dual-task performance in COPD and compared it with healthy controls. …”
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Clinical effect analysis of posterior longitudinal ligament resection during anterior cervical discectomy and fusion in the treatment of cervical spondylotic myelopathy by NIU Hai‐ying, MENG Xiang‐yu, ZUO Shan‐shan, SUN Xiao‐li, LI Yan, LIU Hong‐lei

“…Objective To investigate the effect and safety of microscopic posterior longitudinal ligament resection during anterior cervical discectomy and fusion (ACDF) in the treatment of cervical spondylotic myelopathy (CSM). …”
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Effect of Cananga odorata modulates cholinergic, purinergic enzymes, and elevates antioxidant markers in diabetes-induced cognitive disorder rat brain by Jamiyu A. Saliu, Olajide R. Ojo, Idowu S. Oyeleye, Ganiyu Oboh

“…The typical anti-diabetic medication used as a comparator, ACA, likewise showed efficacy but fell short of the effects of a higher dosage of COLE. Conclusion: In DM-induced cognitive dysfunction, COLE, especially at a dosage of 4 mg, dramatically reduces hyperglycemia, modifies neurotransmitter enzyme activity, and strengthens antioxidant defenses. …”
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Effect of Forbrain Cognitive Training Intervention Prescriptions Based on Risk Factors on Patients with Cognitive Impairment After Traumatic Brain Injury by ZHANG Xueru, WANG Hongbin, CUI Huiying, HAO Xijun, CHEN Changxiang

“…The control group received neurosurgical routine nursing care; the observation group 1 received Forbrain cognitive training (reading training was encouraged) in addition to the routine care; the observation group 2 received the Forbrain cognitive training intervention prescriptions based on the risk factors of cognitive dysfunction (insomnia, headache, depression, low social support and upper limb motor dysfunction) in addition to the routine care. …”
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The Ambivalence of Post COVID-19 Vaccination Responses in Humans by Radha Gopalaswamy, Vivekanandhan Aravindhan, Selvakumar Subbian

“…In this review, we describe different types of COVID-19 vaccines and summarize various adverse effects due to autoimmune and inflammatory response(s) manifesting predominantly as cardiac, hematological, neurological, and psychological dysfunctions. …”
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Utility and cost-effectiveness of LiverMultiScan for MASLD diagnosis: a real-world multi-national randomised clinical trial by Elizabeth Shumbayawonda, Marika French, Jane Elizabeth Carolan, Cayden Beyer, Paula Lorgelly, Dimitar Tonev, Rajarshi Banerjee, Michael H. Miller, Christopher D. Byrne, Janisha Patel, Saima Ajaz, Kosh Agarwal, Johanna Backhus, Minneke J. Coenraad, Jelte J. Schaapman, Andrew Fraser, Miguel Castelo Branco, Stephen Barclay, Matthias M. Dollinger, Daniel J. Cuthbertson, Daniel Forton, Hildo J. Lamb

“…Abstract Background: Increasing prevalence of metabolic dysfunction–associated liver disease (MASLD) and metabolic dysfunction–associated steatohepatitis (MASH) poses a growing healthcare burden. …”
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COMPARATIVE EFFECTS OF MONOTHERAPY WITH MAGNESIUM AND COMBINED THERAPY WITH MAGNESIUM AND Β-BLOCKER ON PRIMARY MITRAL VALVE PROLAPSE WITH HEART RHYTHM DISORDERS by E. G. Nurtdinova, A. N. Zakirova, T. B. Khairetdinova

“…In 12 weeks of treatment groups I and II showed positive dynamics in the MVP manifestations, including significant reduction in severity of the autonomic dysfunction syndrome, ECG positive dynamics, antiarrhythmic effect, decrease in the degree of prolapse, diminution of mitral regurgitation and left auricle volumes. …”
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Effect of traditional Chinese exercise on abnormal lipid metabolism in patients with atherosclerosis: a protocol for meta-analysis of randomised controlled trials by Chen Wang, Peizhen Zhang, Yuting Yang

“…Similarly, performing Baduanjin exercise, Liuzijue Qigong, Wuqinxi exercise and Yijinjing exercise has been found to have a positive effect on lipid metabolism in patients with AS. However, these studies focused only on middle-aged and older populations over 50 years of age and had short intervention periods, poor quality control and patient compliance, and no stratification by age and gender to observe the effects of traditional Chinese exercise (TCE) on patients with AS. …”
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Comparison of Consecutive Therapeutic Effects of Nanoemulsion and Emulsion Cyclosporin in Dry Eye Patients after Short-Term Treatment with Topical Fluorometholone by Yeon Sun Choi, Hae Jung Paik, Dong Hyun Kim

“…To compare the consecutive therapeutic effects of 0.05% emulsion and nanoemulsion cyclosporine (CsA) in dry eye patients after short-term treatment with unpreserved 0.1% fluorometholone (FML). …”
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Effects of deletion of mutant huntingtin in steroidogenic factor 1 neurons on the psychiatric and metabolic phenotype in the BACHD mouse model of Huntington disease. by Barbara Baldo, Rachel Y Cheong, Åsa Petersén

“…Although the mechanisms leading to these aspects are unknown, dysfunction in the hypothalamus, a brain region controlling emotion and metabolism, has been suggested. …”
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Virological and Biochemical Effects of Tenofovir Alafenamide in Different Patient Groups With Chronic Hepatitis B Virus Infection in Real-World Cohort by Erdem Bektas, Aysenur Yilmaz, Cevat Ilteris Kikili, Kanan Nuriyev, Zulal Istemihan, Ibrahim Volkan Senkal, Ziya Imanov, Bilger Cavus, Asli Cifcibasi Ormeci, Filiz Akyuz, Kadir Demir, Selman Fatih Besisik, Sabahattin Kaymakoglu

“…Our findings support that TAF treatment is well-tolerated and effective in patients with chronic HBV infection.…”
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