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3241
Protective effects of curcumin on epileptic rodent models by alleviating oxidative stress and inflammation: a meta-analysis and mechanism exploration
Published 2025-07-01“…Sensitivity analysis and funnel plots suggest robust results, but some publication bias exists.ConclusionCurcumin can effectively improve epileptic seizures and cognitive dysfunction in epileptic rodents through the dual mechanisms of antioxidative stress (inhibiting lipid peroxidation and enhancing antioxidant enzyme activity) and anti-inflammatory (reducing the release of pro-inflammatory factors and inhibiting glial cell activation). …”
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3242
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3243
Cardioprotective effects of L-arginine in a mesatone-induced rat model of chronic heart failure: biochemical and electrocardiographic insights
Published 2025-04-01“…L-arginine exhibits cardioprotective effects. CHF was induced in experimental groups by intramuscular administration of 0.1 mL of a 1 % mesatone solution, followed by daily free swimming until profound fatigue for 21 days. …”
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3244
Effect of DAPAgliflozin on Myocardial Fibrosis and Ventricular Function in Patients with ST-Segment Elevation Myocardial Infarction—DAPA-STEMI Trial
Published 2025-06-01“…<b>Background:</b> Myocardial fibrosis leads to ventricular dysfunction and worsened prognosis, especially after ST-segment elevation myocardial infarction (STEMI). …”
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3245
Effects of dietary curcumin supplementation on the liver health of juvenile channel catfish (Ictalurus punctatus) fed high-starch diet
Published 2025-03-01“…The results showed that HSC0.02 % or HSC0.04 % treatments had no effect on growth performance and HSC0.02 % treatment showed the best hypoglycemic and hypolipidemic effects compared to the HSD group. …”
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3246
Effects of acute cadmium exposure on biochemistry, liver oxidative stress and transcriptomics in Songpu mirror carp (Cyprinus carpio Songpu)
Published 2025-07-01“…Overall, chronic exposure to Cd negatively affects serum parameters, reduces hepatic antioxidant capacity, and leads to lipid metabolism disorders and oxidative stress, resulting in immune dysfunction. The present study effectively broadens our understanding of the mechanisms by which Cd exposure damages fish health and provides a theoretical basis for fish liver immune regulation and aquaculture techniques.…”
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3247
Acute Motor Conduction Block Neuropathy After Initiation of Omalizumab: Case Report and Literature Review for Possible Causality
Published 2024-09-01“…Conflicting evidence exists regarding omalizumab's neurological effects, with proposed mechanisms including autoimmune reactions and mast cell dysfunction. …”
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3248
Complex oteneurological evaluation of vestibular disoders in mild blast traumatic brain injury
Published 2019-05-01“…Due to the non-specific character of the symptoms complex and certain difficulties in clinical evaluation, it is important to develop diagnostic criteria for the vestibular symptoms in patients with blast traumatic brain injury due to the explosive effect for maintaining high quality of life and full social adaptation. …”
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3249
Beta-hydroxybutyrate counteracts the deleterious effects of a saturated high-fat diet on synaptic AMPAR receptors and cognitive performance
Published 2025-09-01“…Here, we investigated whether BHB supplementation could mitigate AMPA receptor trafficking impairments, synaptic dysfunction, and cognitive decline induced by metabolic challenges such as a saturated fat-rich diet. …”
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3250
A network meta-analysis of mind–body exercise interventions for internet addiction symptoms in young adults
Published 2025-06-01“…It severely impacts both physical and mental health, leading to physiological symptoms such as neurological dysfunction and immunosuppression. This condition significantly affects adolescent development and has become a global public health concern. …”
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3251
A novel founder variant in BEST1 gene causing autosomal recessive bestrophinopathy
Published 2025-05-01“…This work aims at documenting the founder effect of a novel variant in the BEST1 gene causing autosomal recessive bestrophinopathy and determining its variable clinical features. …”
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3252
Acupuncture for chronic nonspecific low back pain in middle-aged and older patients: A randomized controlled trial
Published 2024-10-01“…Objective: To observe the specific effects of acupuncture in middle-aged and older patients with chronic nonspecific low back pain (CNSLBP). …”
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3253
Economic evaluations of pharmacological and non-pharmacological interventions for delirium: A systematic review and meta-analysis
Published 2025-06-01“…Background: Delirium, a prevalent cognitive dysfunction in older adults, particularly in hospital and surgical settings, significantly increases patient morbidity, mortality, and healthcare costs. …”
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3254
Berberine Intervention Mitigates Myocardial Ischemia-Reperfusion Injury in a Rat Model: Mechanistic Insights via miR-184 Signaling
Published 2025-02-01“…The miR-184 inhibitor also demonstrated protective effects by modulating key signaling pathways involved in myocardial injury. …”
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3255
Effects of pharmacological and non-pharmacological interventions for the management of sleep problems in people with fibromyalgia: a multi-methods evidence synthesis
Published 2025-05-01“…Participants described how the effectiveness of interventions lessened over time and some felt that medication caused unpleasant side effects. …”
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3256
Effect of continuous Ia fibre activity suppression on hyperreflexia-related spasticity and maladaptive synaptic connections in the spinal cord after injury
Published 2025-07-01“…Current treatments that block spastic muscle contractions do not promote recovery from motor dysfunction. We aimed to confirm that Ia fibre activity suppression, comprising the stretch reflex, reduces spasticity-related hyperreflexia and improves pathological neuronal plastic changes and motor dysfunction. …”
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3257
The chain mediation effect of rumination and worry between the intentionality and content dimensions of mind wandering and internalizing symptoms of depression and anxiety
Published 2025-07-01“…This study aimed to identify dysfunctional types of MW associated with internalizing symptoms of depression and anxiety by distinguishing between the intentionality and content of MW. …”
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3258
Effects of atmospherically relevant PM2.5 on skeletal muscle mitochondria: a review of damage mechanisms and potential of exercise interventions
Published 2025-06-01“…The review underscores the systemic effects on skeletal muscle following mitochondrial dysfunction after PM2.5 exposure and the preventive and treatment potential of exercise.…”
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3259
The Effect of Levocarnitine on Dynamics of the Brain Bioelectrical Activity Formation in Term Infants Delivered by Cesarean Section: Open Randomized Study Results
Published 2017-06-01“…The brain activity of a newborn affects postnatal adaptation, the disorder of which can cause dysfunction of organs and systems of the immature organism and the development of diseases in more distant periods of maturation.Objective: Our aim was to study the effect of levocarnitine on dynamics of the brain bioelectrical activity formation in term infants delivered by cesarean section.Methods. …”
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3260
Comparative effects of different loads of aerobic exercise on lipid metabolism in MASLD rats: a perspective from the gut-liver axis
Published 2025-07-01“…ObjectiveExercise training has been shown to be effective in ameliorating obesity-related diseases, but the therapeutic effects of different loads of exercise on metabolic dysfunction-associated steatotic liver disease (MASLD) as well as the underlying mechanisms by which exercise is based on the enterohepatic axis and thus alleviates MASLD are still unclear. …”
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