Effects of dual-task exercises on cognitive status, disease activity and quality of life in childhood-onset systemic lupus erythematosus by Ozgur Kasapcopur, Sezgin Sahin, Ela Tarakci, Eylul Pinar Kisa, Gokce Leblebici, İrem Yagmur Tonyali, Gulcin Balci, Şehri Dilek, Esma Aslan

“…Objective Many patients with childhood-onset systemic lupus erythematosus (cSLE) suffer from cognitive dysfunction that seriously affects their quality of life, attention, visual and speech memory, motor function, reaction speed and motor perception and physical activity. …”
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Comparative Effectiveness of Myofascial Release and Instrument Assisted Soft-tissue Mobilisation in Improving Flexibility of the Hamstring Muscle: An Experimental Study by Haritima Wadhwa, Megha Nijhawan

“…Aim: To compare the effectiveness of MFR and IASTM on the flexibility of the hamstring muscles. …”
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Mediating Effect of Illness Perception on the Relationship Between Perceived Family Function and Sleep Quality Among Patients With Atrial Fibrillation by Xiaoqing Lu, Zifen An, Yuying Xu, Xi Zhang, Pei Fang, Yaping Lu, Zhongxiang Cai, Liping Yu

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A novel strategy for the protective effect of ginsenoside Rg1 against ovarian reserve decline by the PINK1 pathway by Pengdi Yang, Meiling Fan, Ying Chen, Dan Yang, Lu Zhai, Baoyu Fu, Lili Zhang, Yanping Wang, Rui Ma, Liwei Sun

“…Context The decline in ovarian reserve is a major concern in female reproductive health, often associated with oxidative stress and mitochondrial dysfunction. Although ginsenoside Rg1 is known to modulate mitophagy, its effectiveness in mitigating ovarian reserve decline remains unclear.Objective To investigate the role of ginsenoside Rg1 in promoting mitophagy to preserve ovarian reserve.Materials and methods Ovarian reserve function, reproductive capacity, oxidative stress levels, and mitochondrial function were compared between ginsenoside Rg1-treated and untreated naturally aged female Drosophila using behavioral, histological, and molecular biological techniques. …”
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Effect of preoperative rapamycin supplementation on perioperative clinical frailty and cognitive performance in a murine model undergoing anesthesia and surgery by Ming Ann Sim, Jorming Goh, Jasinda Lee, Jian Hua Tay, Francis Chee Kuan Tan, Chunmei Li, Esther S. P. Wong, Will N. H. Loh, Sophia T. H. Chew, Andrea B. Maier, Brian K. Kennedy, Lian Kah Ti

“…Abstract The geroprotective effects of rapamycin in mitigating frailty and cognitive complications in the perioperative period remains unknown. …”
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Evaluating the Effectiveness of Pegbelfermin in MASH‐Associated Hepatic Fibrosis A Meta‐Analysis and Systematic Review of Randomized Controlled Trials by Muhammad Shahzil, Fariha Hasan, Syeda Kanza Kazmi, Manesh Kumar Gangwani, UmmeSalma Shabbar, Ammad Javaid Chaudhary, Muhammad Ali Khaqan, Muhammad Saad Faisal, Kathy N. Williams, Babu P. Mohan, Christina Tofani

“…Meta‐analyses were performed with RevMan 5.4 using a random‐effects model. Results Data from 452 participants across three RCTs were analyzed. …”
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Case Report: Therapeutic effect of efgartigimod in refractory anti-GQ1b antibody syndrome coexisting with myasthenia gravis by Keiko Watanabe, Seiya Takahashi, Akane Kanda, Takuya Watanabe, Yuki Kakinuma, Satoshi Yano, Ryuta Kinno, Ryuta Kinno

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LONG-TERM EFFECT OF CONTINUOUS POSITIVE AIRWAY PRESSURE THERAPY (CPAP) IN HYPERTENSIVE PATIENTS WITH SLEEP APNEA AND METABOLIC IMPAIRMENT by M. V. Gorbunova, S. L. Babak, A. G. Maliavin

“…Objective: Obstructive sleep apnea (OSA) is associated with the high prevalence of cardiovascular diseases, and such disease manifestations as obesity, arterial hypertension (AH), violation of carbohydrate metabolism, dyslipidemia and endothelial dysfunction. However, the effects of Continuous Positive Airway Pressure therapy (Continuous Positive Airway Pressure — CPAP therapy) on the normalization of blood pressure in patients with OAS+AH are poorly understood and poorly studied. …”
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Toxicological and histopathological effects of sodium benzoate used in commercially available fruit juice on liver and kidney tissue in mice model by Dina Akter, Md Meskatul Islam, Md Imam Hossain, Md Esrafil, Bishnu Pada Dey, Luthfunnesa Bari, Md Abu Zubair

“…Summary: Aim: This study was designed to explore the toxic effects of SB overuse on blood biochemical and histopathological changes in mice. …”
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Metabolic Effects of Testosterone Replacement Therapy in Patients with Type 2 Diabetes Mellitus or Metabolic Syndrome: A Meta-Analysis by Shu-ying Li, Ya-ling Zhao, Yu-fan Yang, Xi Wang, Min Nie, Xue-yan Wu, Jiang-feng Mao

“…Recent compiling evidence shows that TRT has beneficial metabolic effects on these patients. Objective. A meta-analysis has been conducted to evaluate the effects of TRT on cardiovascular metabolic factors. …”
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Effect of Robot-Assisted Therapy on Participation of People with Limited Upper Limb Functioning: A Systematic Review with GRADE Recommendations by Fernanda M. R. M. Ferreira, Maria Emília A. Chaves, Vinícius C. Oliveira, Jordana S. R. Martins, Claysson B. S. Vimieiro, Adriana M. V. N. Van Petten

“…Previous studies have suggested that robot-assisted therapy (RT) is effective in treating impairment and that it may also improve individuals’ participation. …”
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The Effects of Glucagon‐Like Peptide‐1 Receptor Agonists on Mitochondrial Function Within Skeletal Muscle: A Systematic Review by Victoria J. Old, Melanie J. Davies, Dimitris Papamargaritis, Pratik Choudhary, Emma L. Watson

“…However, up to 40% of the weight lost with GLP‐1 RAs comes from lean body mass, raising concerns about potential adverse effects on skeletal muscle function. Mitochondrial dysfunction, characterized by reduced mitochondrial size and activity, is prevalent in individuals with obesity and T2DM and is a known contributor to muscle wasting in ageing and some chronic diseases. …”
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Development of a Competitive Nutrient-Based T-Cell Immunotherapy Designed to Block the Adaptive Warburg Effect in Acute Myeloid Leukemia by Huynh Cao, Jeffrey Xiao, David J. Baylink, Vinh Nguyen, Nathan Shim, Jae Lee, Dave J. R. Mallari, Samiksha Wasnik, Saied Mirshahidi, Chien-Shing Chen, Hisham Abdel-Azim, Mark E. Reeves, Yi Xu

“…Leukemia blasts possess enhanced glycolysis (Warburg effect), exploiting their microenvironment to deprive nutrients (e.g., glucose) from T cells, leading to T-cell dysfunction and leukemia progression. …”
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Contemporary approaches to correction of cognitive impairment in endogenous depression by I. V. Oleichik, T. I. Shishkovskaia, P. A. Baranov

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The Effect of Potentially Hepatotoxic Medicinal Products on Alanine Transaminase Levels in COVID-19 Patients: A Case–Control Study by V. I. Petrov, A. Yu. Ryazanova, N. S. Tokareva

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The effect of therapy on subclinical atherosclerosis of the carotid arteries in patients with calcium pyrophosphate crystal deposition disease and osteoarthritis (pilot study) by M. S. Eliseev, O. V. Zhelyabina, M. N. Chikina, E. I. Markelova, I. G. Kirillova, Yu. O. Korsakova, A. A. Kobriseva

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Therapeutic effects of curcumin and piperine combination in critically ill patients with sepsis: a randomized double-blind controlled trial by Babak Alikiaii, Narges Khatib, Mohaddeseh Badpeyma, Esmat Hasanzadeh, Saeed Abbasi, Sepide Amini, Zahra Kiani, Shirin Hassanizadeh, Zahra Iraj, Amirhossein Sahebkar, Anju Majeed, Mohammad Bagherniya

“…Abstract Background Sepsis, an organ dysfunction caused by deregulated host response to infection, is a major health problem worldwide. …”
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Cardioprotective Effect of Growth Differentiation Factor 15 Against Isoproterenol-Induced Cardiomyocyte Apoptosis via Regulation of the Mitochondrial Fusion by Yan Zhang, Zhu Mei, Xiaodong Jia, Haixu Song, Jing Liu, Xiaoxiang Tian, Tianyu Xu, Xiaoxia Fu

“…Growth differentiation factor 15 (GDF15) dramatically increases during cardiac hypertrophy and dysfunction, but its functions and mechanisms are barely known. …”
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Rehabilitation effect on psycho-emotional well-being in women with surgically treated vulvar cancer: a randomised controlled trial by Blinov V. Dmitry, Antonina G. Solopova, Elena V. Gameeva, Nazim G. Badalov, Vsevolod N. Galkin, Mikhail A. Eremushkin, Alexandra M. Stepanova, Alexander E. Ivanov, Olga S. Gridasova

“…Surgical treatment of vulvar cancer (VC) entails mental and somatic disturbances due to pain, body image changes, and sexual dysfunction, which are closely associated with impaired social functioning and reduced overall quality of life. …”
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Iron-catalyzed oxidative stress compromises cancer promotional effect of BRCA2 haploinsufficiency through mitochondria-targeted ferroptosis by Yuki Maeda, Yashiro Motooka, Shinya Akatsuka, Hideaki Tanaka, Tomoji Mashimo, Shinya Toyokuni

“…Mechanistically, mitochondrial dysfunction with excess iron, promoted by insufficient BRCA2 presumably for maintaining DNA integrity, eventually initiated ferroptotic process. …”
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