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Synergistic Neuroprotective and Immunomodulatory Effects of Cocoa Seed Husk and Guarana Extract: A Nutraceutical Approach for Parkinson’s Disease Management
Published 2025-03-01“…Background: Parkinson’s disease (PD) is a progressive neurodegenerative disorder linked to oxidative stress, mitochondrial dysfunction, and neuroinflammation. This study evaluates the neurofunctional and immunomodulatory effects of an aqueous extract combining cocoa seed husk and guarana powder (GuaCa). …”
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Toxic Effects of 3,3′-Iminodipropionitrile on Vestibular System in Adult C57BL/6J Mice In Vivo
Published 2020-01-01“…This work focused on the epithelial cell loss, vestibular dysfunction, and spontaneous cell regeneration after IDPN administration. …”
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Pomiferin Exerts Antineuroinflammatory Effects through Activating Akt/Nrf2 Pathway and Inhibiting NF-κB Pathway
Published 2022-01-01“…Neurodegenerative diseases, including Alzheimer’s disease, Parkinson’s disease, and Huntington’s disease, are mainly characterized by progressive motor, sensory, or cognitive dysfunction in patients. Such diseases mostly occur in middle-aged and elderly people, and there is no effective cure. …”
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Analysis of clinical and epidemiological interactions of phenol and phthalate levels in blood and urine with anamnestic and biochemical health measures during the formation of mult...
Published 2023-09-01“…Phenol and its derivatives (eg. parabens), phthalates and a number of other aromatic compounds exhibit various toxic effects when entering the human body due to unfavorable ecology, smoking, intake with food and medications. …”
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Effect of Every-other-day Fasting on Level of Serum TNF-α in Rats after Acute Spinal Cord Injury
Published 2015-12-01“…Objective:To observe the effect of every-other-day fasting (EODF) on serum tumor necrosis factor-α (TNF-α) level in rats after acute spinal cord injury.Methods:A total of 48 female adult Wistar rats were randomly divided into EODF group (group A), normal diet control group (group B) and sham-operated group (group C). …”
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COMPARISON OF FOSINOPRIL AND ATENOLOL EFFECT ON HEART 0.1 HZ-RHYTHMS SYNCHRONIZATION AND BLOOD MICROCIRCULATION IN PATIENTS WITH ARTERIAL HYPERTENSION
Published 2016-01-01“…Fosinopril and atenolol showed comparable effect on blood pressure (BP) reduction. Atenolol decreased in heart rate significantly. …”
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THE EFFECT OF AN ANTI-TUMOR NECROSIS FACTOR-? AGENT ON DISEASE ACTIVITY,BLOOD RHEOLOGICAL PROPERTIES, AND THE ARTERIAL WALL IN PSORIATIC ARTHRITIS
Published 2010-06-01“…Treatment with anti-TNF- agents is effective in inhibiting inflammation in PsA; however, their effect on the wall of large arteries has not been studied. …”
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Effectiveness of Petai (Parkia speciosa) Ethanol Extract in Controlling Foam Cell Numbers in Atherosclerosis-Induced Male Wistar Rats
Published 2024-12-01“…Atherosclerosis has a complex pathophysiology, such as endothelial dysfunction, thickening of the tunica intima, and the formation of atheromatous plaques. …”
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Effects of intermittent theta burst stimulation on upper limb motor recovery in early stroke patients: an fNIRS study
Published 2025-02-01“…This study provides evidence that iTBS is an effective rehabilitation strategy poststroke.Clinical trial registrationhttps://www.chictr.org.cn/showproj.html?…”
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Effect of alprostadil combined with beraprost sodium tablet sequential therapy in early mutation and long term survival of arteriovenous fistula
Published 2015-01-01“…Objective To observe the effect of alprostadil combined with beraprost sodium tablet sequential therapy in early mutation and long term survival of arteriovenous fistula(AVF).Methods Weretrospectively analyzed 312 uraemia patients who received AVF operation first time between January 2013 and March 2014.All patients were given radialartery-cephalic vein standard fistulation.Forty-six patients were administered alprostadil(20 μg i.v.drip for 3 days in hospital) combined with beraprost sodium tablet(20 μg P.O.for 3 months for outpatient) sequential therapy as study group.Forty-six patients without treatment of alprostadil or beraprost sodium were included into control group.These two groups had the same clinical materials,such as age,the diameter of artery and vein before operation,primary disease constitution rate.The fistula dysfunctional rate in 1 year,fistula mutation time,average fistula flow volume and arterial end diastolic velocity 1 year postoperation were assessed.Results In study and control groups,the fistula dysfunctional rate was 10.9%and28.2%respectively(P=0.035 5),the mean maturation time was(42.1±6.5)and(55.5±5.8) days respectively(P<0.001),the mean blood flow was(789 ± 101) and(556 ± 132) mL/min respectively(P<0.001),and the arterial end diastolic velocity was(151.5 ± 14.5) and(113 ± 20.1) cm/s respectively(P<0.001).Conclusions Our data indicated that the sequential therapy of alprostadil combined with beraprost sodium tablet is effective and safe for the prevention of primary AVF failure in hemodialysis patients and early fistula dysfunction.…”
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Effect of composite collagen containing hydrogel on the functional activity of fibroblasts after acid-induced <i>in vitro</i> injury
Published 2024-06-01“…To evaluate the effect of a composite hydrogel containing dermal components on the functional activity of intact fibroblasts and fibroblasts with acid-induced dysfunction.Materials and methods. …”
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Protective effects of gallic acid against nickel-induced kidney injury: impact of antioxidants and transcription factor on the incidence of nephrotoxicity
Published 2024-12-01“…Gallic acid has a protective role against kidney dysfunction and renal damage in Ni-nanoparticle toxicity.…”
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Investigation of the Effectiveness of Transcutaneous Auricular Vagus Nerve Stimulation (taVNS) and Vestibular Rehabilitation in Patients with Unilateral Vestibular Hypofunction
Published 2025-05-01“…While the mechanism of improvement in diseases such as epilepsy, dementia, and depression is being studied, its potential effect on vestibular dysfunction is also being investigated. …”
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The Effect of Spirulina Algae (Arthrospira platensis) Extract on the Differentiation of Bone Marrow Derived Mesenchymal Stem Cells to Neuron Cells
Published 2025-07-01“…Background: Neurodegenerative diseases cause dysfunction of the nervous system and the loss of neurons. …”
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Real-world Effectiveness and Safety of Janus Kinase Inhibitors in Alopecia Areata: A Retrospective Cohort Study of 72 Patients
Published 2025-04-01“…Two serious adverse events occurred (sickle cell crisis and renal failure with pre-existing dysfunction). The findings indicate that JAKi are effective and safe for AA treatment in real-world settings. …”
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Protective Effect of <i>Dictyophora rubrovolvata</i> Extract on Intestinal and Liver Tissue Toxicity Induced by Metformin Disinfection Byproducts
Published 2025-04-01“…Metformin disinfection byproducts Y and C have emerged as pollutants of concern in drinking water systems and are suspected to possess significant toxicity to mammals. However, effective strategies to mitigate the effects of Y and C exposure in mammals have not been thoroughly formulated. …”
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