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  1. 3081

    Modulatory effects of perindopril on cisplatin-induced nephrotoxicity in mice: Implication of inflammatory cytokines and caspase-3 mediated apoptosis by Aljuhani Naif, Ismail Raed S., El-Awady Mohammed S., Hassan Memy H.

    Published 2020-12-01
    “…Cisplatin-induced nephrotoxicity limits its anticancer effectiveness, thus this study’s aim was to assess the potential modulatory effect of perindopril on cisplatin-induced nephrotoxicity and to elucidate the possible underlying mechanisms. …”
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    Article
  2. 3082

    Effects of six Chinese mind-body exercise therapies on glycolipid metabolism and vascular endothelial function in hypertensive patients by Haojie Li, Xinyu Lin, Xinglu Li, Nan Chen, Xie Wu

    Published 2025-06-01
    “…These evidence-based results support incorporating traditional exercises into hypertension management protocols to address both metabolic and vascular dysfunction.…”
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    Article
  3. 3083

    The Protective Effect of Radix Polygoni Multiflori on Diabetic Encephalopathy via Regulating Myosin Light Chain Kinase Expression by Yu He, Feng Wang, Shiqiang Chen, Mi Liu, Wei Pan, Xing Li

    Published 2015-01-01
    “…In this study we tried to explore the effect of Radix Polygoni Multiflori on cognitive function among diabetic rats with demonstrated cognitive impairment. …”
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    Article
  4. 3084

    Therapeutic Effects of GLP-1 Receptor Agonists and DPP-4 Inhibitors in Neuropathic Pain: Mechanisms and Clinical Implications by Yaswanth Kuthati, Venkata Naga Goutham Davuluri, Chih-Shung Wong

    Published 2025-04-01
    “…These effects imply a therapeutic perspective for GLP-1RA and DPP-4i therapies in neuropathic pain treatment. …”
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    Article
  5. 3085

    Immunomodulatory Effects of Vitamin D3 on the Expression of IL-6, IFN-ã and T-BET in Inflammatory Bowel Diseases by 1,2 1 Alhassan H.M. * and Yaraghi A.S.

    Published 2024-03-01
    “…Inflammatory bowel diseases (IBD) is an immune mediated dysfunction in a genetically susceptible host. Crohn's diseases (CD) and ulcerative colitis (UC) are serotypes of IBD. …”
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    Article
  6. 3086

    Survivorship Considerations and Management in the Adolescent and Young Adult Sarcoma Population: A Review by Allison Gunderson, Miriam Yun, Babe Westlake, Madeline Hardacre, Nicholas Manguso, Alicia A. Gingrich

    Published 2025-04-01
    “…This article discusses the survivorship considerations in this young population of cancer patients who complete therapy. The lasting side effects include surgical and radiation-related morbidity, chemotherapy toxicity, early and late secondary effects on other organ systems, such as cardiac and endocrine dysfunction, and the development of secondary cancers. …”
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    Article
  7. 3087
  8. 3088
  9. 3089

    Heat Shock Protein 70 Mediates the Protective Effect of Naringenin on High-Glucose-Induced Alterations of Endothelial Function by Zhihan Zhang, Hui Liu, Xiang Hu, Yikang He, Lu Li, Xinyu Yang, Changhua Wang, Mingbai Hu, Shengxiang Tao

    Published 2022-01-01
    “…Endothelial dysfunction plays a pivotal role in the development and progression of diabetic vascular complications. …”
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    Article
  10. 3090

    Effects of pharmacological inhibition of fatty acid amide hydrolase on corticosterone release: a systematic review of preclinical studies by Christina F. Pereira, Isabelle Boileau, Stefan Kloiber

    Published 2025-04-01
    “…Abstract Psychiatric conditions are often linked to dysfunction of the Hypothalamic–Pituitary–Adrenal (HPA) axis. …”
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    Article
  11. 3091

    Effect of Al2O3NPs on gene expression in Daphnia magna: Implications for environmental risk assessment by Nina Doskocz, Katarzyna Affek, Magdalena Matczuk, Monika Załęska-Radziwiłł

    Published 2025-01-01
    “…Results from qRT-PCR after 48 h and 21 days of exposure revealed increased expression of oxidative stress-related genes (cat, gst) and mitochondrial dysfunction-related genes (nadh). These findings highlight the persistent bioactivity and potential toxicity of NPs even post-treatment, emphasizing the need for effective monitoring and regulation. …”
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    Article
  12. 3092

    Systemic semaglutide provides a mild vasoprotective and antineuroinflammatory effect in a rat model of ocular hypertensive glaucoma by Zaynab A. Mouhammad, Anne Rombaut, Mariana Yolotzin García Bermúdez, Rupali Vohra, James R. Tribble, Pete A. Williams, Miriam Kolko

    Published 2025-07-01
    “…In conclusion, our findings suggest that GLP-1RAs may exert neuroprotective effects by delaying IOP elevation and preventing OHT-induced reactive astrocyte and vascular remodeling. …”
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    Article
  13. 3093

    The Effect of Audible Joint Manipulation Sounds in the Upper Cervical Spine on Brain Wave and Autonomic Nervous System Activity by Dalton Whitman, Rob Sillevis, Matthew Frommelt

    Published 2025-01-01
    “…Background: High-velocity, low-amplitude (HVLA) manipulation is a common manual therapy technique used for treating pain and musculoskeletal dysfunction. An audible manipulation sound is commonly experienced by patients who undergo HVLA manipulation; however, there is little known about the effects and clinical relevance of the audible manipulation sound on cortical output and the autonomic nervous system. …”
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  14. 3094

    The Effect of Specific Immunotherapy on Natural Killer T cells in Peripheral Blood of House Dust Mite-Sensitized Children with Asthma by Lu Yan-ming, Cao Lan-fang, Li Chen, Li Ya-qin, Chen Wei, Zhang Wen-ming

    Published 2012-01-01
    “…These results suggest that the pathogenesis of asthma may be related to the ratio and dysfunction of NKT and CD4+NKT cells.…”
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  15. 3095

    Protective Effect of Nano-Vitamin C on Infertility due to Oxidative Stress Induced by Lead and Arsenic in Male Rats by Mahdieh Raeeszadeh, Behzad Karimfar, Ali Akbar Amiri, Abolfazl Akbari

    Published 2021-01-01
    “…However, there is a new view that shows that the nano form of vitamins such as vitamin C, which have antioxidant activity, can be effective in improving this disorder. Therefore, this study aimed to evaluate the effect of NVC (NVC) on reproductive toxicity caused by the combination of Pb and As on testicular histology, sperm morphology, oxidative stress parameters, and hormonal changes in male rats. …”
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    Article
  16. 3096

    The effect of four weeks dynamic warm-up on static and dynamic balance and proprioceptive receptors in skilled female Gymnast by فرشته احمد آبادی, سید محسن آوندی

    Published 2016-05-01
    “…Purpose: The aim of this study was to investigate the effect of four weeks dynamic warm-up on static and dynamicbalance and proprioceptive receptors in skilled female Gymnast Methodology: For this purpose, 16 skilled femalegymnasts (mean age 9.62±1.45 years, height 130 ±15.62 cm, weight 28.24 ±8.52 kg and BMI 16.27±1.46kg/m2) wereselected and divide into two groups [general warm-up (control), and dynamic stretching] randomly. …”
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  17. 3097

    Effects of hyperuricemia on renal function of renal transplant recipients: a systematic review and meta-analysis of cohort studies. by Yan Huang, Yu-Lin Li, He Huang, Ling Wang, Wen-Ming Yuan, Jing Li

    Published 2012-01-01
    “…<h4>Conclusions</h4>Current evidence suggests that hyperuricemia may be an independent risk factor of allograft dysfunction. Hyperuricemia may modestly increase the risk of poor outcomes of RTRs. …”
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    Article
  18. 3098

    Naringin mitigated doxorubicin-induced kidney injury by the reduction of oxidative stress and inflammation with a synergistic anticancer effect by Nahla S. Gad, Sameh M. Shabana, Maggie E. Amer, Azza I. Othman, Mohamed A. El-Missiry

    Published 2025-06-01
    “…The nephroprotective effect of NG on DOX-induced kidney toxicity was investigated to increase its utility in clinical settings. …”
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  19. 3099
  20. 3100

    Investigating the Effect and Mechanism of 3-Methyladenine Against Diabetic Encephalopathy by Network Pharmacology, Molecular Docking, and Experimental Validation by Jiaxin Chu, Jianqiang Song, Zhuolin Fan, Ruijun Zhang, Qiwei Wang, Kexin Yi, Quan Gong, Benju Liu

    Published 2025-04-01
    “…However, the pharmacological mechanisms underlying 3-MA’s therapeutic effects on diabetic microvascular complications remain incompletely understood, owing to the intricate and multifactorial pathogenesis of DE. …”
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    Article