Suggested Topics within your search.
Suggested Topics within your search.
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3081
Modulatory effects of perindopril on cisplatin-induced nephrotoxicity in mice: Implication of inflammatory cytokines and caspase-3 mediated apoptosis
Published 2020-12-01“…Cisplatin-induced nephrotoxicity limits its anticancer effectiveness, thus this study’s aim was to assess the potential modulatory effect of perindopril on cisplatin-induced nephrotoxicity and to elucidate the possible underlying mechanisms. …”
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3082
Effects of six Chinese mind-body exercise therapies on glycolipid metabolism and vascular endothelial function in hypertensive patients
Published 2025-06-01“…These evidence-based results support incorporating traditional exercises into hypertension management protocols to address both metabolic and vascular dysfunction.…”
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3083
The Protective Effect of Radix Polygoni Multiflori on Diabetic Encephalopathy via Regulating Myosin Light Chain Kinase Expression
Published 2015-01-01“…In this study we tried to explore the effect of Radix Polygoni Multiflori on cognitive function among diabetic rats with demonstrated cognitive impairment. …”
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3084
Therapeutic Effects of GLP-1 Receptor Agonists and DPP-4 Inhibitors in Neuropathic Pain: Mechanisms and Clinical Implications
Published 2025-04-01“…These effects imply a therapeutic perspective for GLP-1RA and DPP-4i therapies in neuropathic pain treatment. …”
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3085
Immunomodulatory Effects of Vitamin D3 on the Expression of IL-6, IFN-ã and T-BET in Inflammatory Bowel Diseases
Published 2024-03-01“…Inflammatory bowel diseases (IBD) is an immune mediated dysfunction in a genetically susceptible host. Crohn's diseases (CD) and ulcerative colitis (UC) are serotypes of IBD. …”
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3086
Survivorship Considerations and Management in the Adolescent and Young Adult Sarcoma Population: A Review
Published 2025-04-01“…This article discusses the survivorship considerations in this young population of cancer patients who complete therapy. The lasting side effects include surgical and radiation-related morbidity, chemotherapy toxicity, early and late secondary effects on other organ systems, such as cardiac and endocrine dysfunction, and the development of secondary cancers. …”
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3087
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3089
Heat Shock Protein 70 Mediates the Protective Effect of Naringenin on High-Glucose-Induced Alterations of Endothelial Function
Published 2022-01-01“…Endothelial dysfunction plays a pivotal role in the development and progression of diabetic vascular complications. …”
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3090
Effects of pharmacological inhibition of fatty acid amide hydrolase on corticosterone release: a systematic review of preclinical studies
Published 2025-04-01“…Abstract Psychiatric conditions are often linked to dysfunction of the Hypothalamic–Pituitary–Adrenal (HPA) axis. …”
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3091
Effect of Al2O3NPs on gene expression in Daphnia magna: Implications for environmental risk assessment
Published 2025-01-01“…Results from qRT-PCR after 48 h and 21 days of exposure revealed increased expression of oxidative stress-related genes (cat, gst) and mitochondrial dysfunction-related genes (nadh). These findings highlight the persistent bioactivity and potential toxicity of NPs even post-treatment, emphasizing the need for effective monitoring and regulation. …”
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3092
Systemic semaglutide provides a mild vasoprotective and antineuroinflammatory effect in a rat model of ocular hypertensive glaucoma
Published 2025-07-01“…In conclusion, our findings suggest that GLP-1RAs may exert neuroprotective effects by delaying IOP elevation and preventing OHT-induced reactive astrocyte and vascular remodeling. …”
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3093
The Effect of Audible Joint Manipulation Sounds in the Upper Cervical Spine on Brain Wave and Autonomic Nervous System Activity
Published 2025-01-01“…Background: High-velocity, low-amplitude (HVLA) manipulation is a common manual therapy technique used for treating pain and musculoskeletal dysfunction. An audible manipulation sound is commonly experienced by patients who undergo HVLA manipulation; however, there is little known about the effects and clinical relevance of the audible manipulation sound on cortical output and the autonomic nervous system. …”
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3094
The Effect of Specific Immunotherapy on Natural Killer T cells in Peripheral Blood of House Dust Mite-Sensitized Children with Asthma
Published 2012-01-01“…These results suggest that the pathogenesis of asthma may be related to the ratio and dysfunction of NKT and CD4+NKT cells.…”
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3095
Protective Effect of Nano-Vitamin C on Infertility due to Oxidative Stress Induced by Lead and Arsenic in Male Rats
Published 2021-01-01“…However, there is a new view that shows that the nano form of vitamins such as vitamin C, which have antioxidant activity, can be effective in improving this disorder. Therefore, this study aimed to evaluate the effect of NVC (NVC) on reproductive toxicity caused by the combination of Pb and As on testicular histology, sperm morphology, oxidative stress parameters, and hormonal changes in male rats. …”
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3096
The effect of four weeks dynamic warm-up on static and dynamic balance and proprioceptive receptors in skilled female Gymnast
Published 2016-05-01“…Purpose: The aim of this study was to investigate the effect of four weeks dynamic warm-up on static and dynamicbalance and proprioceptive receptors in skilled female Gymnast Methodology: For this purpose, 16 skilled femalegymnasts (mean age 9.62±1.45 years, height 130 ±15.62 cm, weight 28.24 ±8.52 kg and BMI 16.27±1.46kg/m2) wereselected and divide into two groups [general warm-up (control), and dynamic stretching] randomly. …”
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3097
Effects of hyperuricemia on renal function of renal transplant recipients: a systematic review and meta-analysis of cohort studies.
Published 2012-01-01“…<h4>Conclusions</h4>Current evidence suggests that hyperuricemia may be an independent risk factor of allograft dysfunction. Hyperuricemia may modestly increase the risk of poor outcomes of RTRs. …”
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Naringin mitigated doxorubicin-induced kidney injury by the reduction of oxidative stress and inflammation with a synergistic anticancer effect
Published 2025-06-01“…The nephroprotective effect of NG on DOX-induced kidney toxicity was investigated to increase its utility in clinical settings. …”
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Investigating the Effect and Mechanism of 3-Methyladenine Against Diabetic Encephalopathy by Network Pharmacology, Molecular Docking, and Experimental Validation
Published 2025-04-01“…However, the pharmacological mechanisms underlying 3-MA’s therapeutic effects on diabetic microvascular complications remain incompletely understood, owing to the intricate and multifactorial pathogenesis of DE. …”
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