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Suggested Topics within your search.
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Differential Effects of Methyl-4-Phenylpyridinium Ion, Rotenone, and Paraquat on Differentiated SH-SY5Y Cells
Published 2013-01-01“…We compared the toxicity of these three neurotoxicants using differentiated dopaminergic SH-SY5Y human cells, aiming to elucidate their differential effects. PQ-induced neurotoxicity was shown to be concentration and time dependent, being mitochondrial dysfunction followed by neuronal death. …”
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Ruxolitinib Has a Protective Effect on Ovarian and Endometrial Tissues in Diabetic Rats via STAT3 Pathway
Published 2024-09-01“…We aimed to examine the potential protective effect of ruxolitinib, on ovarian dysfunction by comparing biochemical, pro-inflammatory, and histological abnormalities in a diabetic rat model. …”
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Drug-Induced Liver Injury: Mechanisms, Diagnosis, and Management: A Review
Published 2025-05-01“…The liver functions as the main detoxifying organ of the body therefore, it becomes easily susceptible to destructive effects from the medicine components as well as other substances such as herbal supplements. …”
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Population-Based Propensity Score-Matched Analysis of Paxlovid and Molnupiravir Effectiveness in High-Risk COVID-19 Patients
Published 2025-03-01“…Additionally, Molnupiravir was effective in patients with severe hepatic or renal dysfunction (aOR = 0.44, 95% CI: 0.35-0.54), who are not eligible for Paxlovid. …”
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Interaction between the non-alcoholic fatty liver disease fibrosis score and vitamin D deficiency on left ventricular hypertrophy and impaired diastolic function in patients with t...
Published 2025-08-01“…Abstract Aims The present study aimed to evaluate the effect of Non-Alcoholic Fatty Liver Disease Fibrosis Score (NFS), vitamin D deficiency, and their interaction on the Left Ventricle (LV) structure and diastolic function in type 2 diabetes mellitus (T2DM) patients. …”
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3066
Fecal microbiota transplantation improves hepatic steatosis induced by HFD in a mouse model associated with liver ILC1 regulation and indole-3-carbinol level
Published 2025-02-01“…BackgroundThe prevalence of metabolic dysfunction-associated steatotic liver disease (MASLD) has increased worldwide. …”
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3067
Mapping the Olfactory Brain: A Systematic Review of Structural and Functional Magnetic Resonance Imaging Changes Following COVID-19 Smell Loss
Published 2025-06-01“…Background: Olfactory dysfunction (OD)—including anosmia and hyposmia—is a common and often persistent outcome of viral infections. …”
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Effects of Conservative Oxygen Therapy versus Conventional Oxygen Therapy on the Mortality in ICU Patients: A Meta-Analysis
Published 2023-01-01“…Objective. To compare the effects of conservative oxygen therapy and conventional oxygen therapy on the mortality of critically ill patients in ICU. …”
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Effect of Mirror Image Therapy Combined with Whole Body Vibration Training on Unilateral Spatial Neglect after Stroke
Published 2022-02-01“…After 8 weeks of treatment, the CBS scores of the three groups were significantly lower than those before treatment, however MMSE, FMA and BI scores were significantly higher than those before the treatment, but the combined group was better than the mirror image group and the whole body vibration training group, and the difference was statistically significant respectively (<italic>P</italic><0.05).ConclusionMirror image therapy combined with whole body vibration training can effectively improve the degree of spatial neglect and cognitive dysfunction in patients with unilateral spatial neglect after stroke, and enhance upper limb motor function and self-care ability.…”
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Effects of Graphene Quantum Dots on Renal Fibrosis Through Alleviating Oxidative Stress and Restoring Mitochondrial Membrane Potential
Published 2025-03-01“…In animal models of Adriamycin‐induced nephropathy and 5/6 subtotal nephrectomy, GQDs treatment exhibits anti‐inflammatory, anti‐fibrotic, and anti‐apoptotic effects by restoring podocyte actin structure. These therapeutic benefits are associated with the downregulation of transient receptor potential channel 5 (TRPC5) activity, which is related to kidney fibrosis and mitochondrial dysfunction. …”
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A comprehensive mechanism of biological and health effects of anthropogenic extremely low frequency and wireless communication electromagnetic fields
Published 2025-06-01“…The IFO-VGIC mechanism and the consequent OS constitute a comprehensive mechanism that explains all known adverse biological and health effects reported to be induced by anthropogenic EMFs.…”
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ACE INHIBITORS IN PATIENTS WITH ISCHEMIC HEART DISEASE WITHOUT HEART FAILURE: CLASS EFFECTS AND EFFICACY OF ITS REPRESENTATIVES
Published 2015-12-01“…Favorable therapeutic effects of inhibiting RAS activity in patients without left ventricle dysfunction are demonstrated in studies EUROPA with perindopril 8 mg, and HOPE with ramipril 10 mg. …”
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Unveiling the dynamic effects of major depressive disorder and its rTMS interventions through energy landscape analysis
Published 2025-03-01“…Notably, rTMS intervention partially reverses the identified dynamical alterations.DiscussionOur results shed light on the intrinsic dysfunction mechanisms of MDD from a dynamic standpoint and highlight the effects of rTMS intervention. …”
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The effect of ginseng on sexual function in postmenopausal women with major depression: a triple-blind randomized controlled trial
Published 2025-06-01“…Anxiety, fear, and depression in postmenopausal women may further deteriorate sexual dysfunction. Utilizing modern and effective methods to enhance sexual desire in these women is a priority in midwifery care. …”
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Effects of Cerebellar Transcranial Magnetic Stimulation on the Motor Function of Patients With Stroke: A Systematic Review and Meta‐Analysis
Published 2025-04-01“…In recent years, there has been an increase in the number of studies on the application of cerebellar transcranial magnetic stimulation (cTMS) to motor dysfunction in patients with stroke. This review aims to analyze cTMS efficacy for stroke patients and further explore the specific effects of different stages of the disease, stimulation modes, stimulation intensity, and treatment duration. …”
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Correlation between fear of cancer recurrence and levels of mindfulness in patients with gastric cancer: mediating effects of couple support
Published 2024-12-01“…The Bootstrap method was used to verify the mediating effect of marital support on the FCR and mindfulness level in gastric cancer patients.Results A total of 120 patients were included. …”
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