Unleashing the Power of Cold Atmospheric Plasma: Inducing Mitochondria Damage‐Mediated Mitotic Catastrophe by Shengjie Peng, Yue Feng, K.N. Yu, Lijun Wu, Guodong Chen, Miaomiao Yang, Lele Zhao, Wei Cao, Qianwen Cui, Lianjun Chen, Quan Li, Yifan Huang, Cheng Cheng, Fengqin Zhu, Wei Han

“…Significantly, it is showed that different from high‐dose treatments, CAP decreased the doses to the low‐dose range but still exhibited anti‐tumor effects via mitotic catastrophe. Unlike radiotherapy or chemotherapy, low‐dose CAP treatment induces mitochondrial structural damage and dysfunction, disrupts energy metabolism and redox balance, and results in mitotic catastrophe. …”
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Glyceraldehyde derivatives inspired by empagliflozin as potential anti-heart failure agents independent of glucose-lowering effects by Xiao Li, Yue Yao, Luoyifan Zhou, Jin Yang, Xin Chen, Chao Zhang, Manjiong Wang, Jian Li, Baoli Li, Yixiang Xu

“…In vivo efficacy results demonstrated that compound 12 at 10 mg/kg significantly ameliorated cardiac dysfunction, myocardial fibrosis, and exercise tolerance in isoproterenol-induced heart failure mice without a glucose-lowering effect. …”
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Intensity Sensitive Modulation Effect of Theta Burst Form of Median Nerve Stimulation on the Monosynaptic Spinal Reflex by Kuei-Lin Yeh, Po-Yu Fong, Ying-Zu Huang

“…The effects of electrical stimulation of median nerve with a continuous theta burst pattern (EcTBS) on the spinal H-reflex were studied. …”
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Effect of yoga and counselling on mental health issues among adolescents in an urban slum of Mumbai: An Interventional Study by Kinjal Chauhan, ,Sanjay Panchal, ,Vinay Kumar, ,Vandana Kashyap

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Mindful Eating: A Deep Insight Into Fructose Metabolism and Its Effects on Appetite Regulation and Brain Function by Gabriela Vanessa Flores Monar, Camila Sanchez Cruz, Ernesto Calderon Martinez

“…Fructose, a common sweetener in modern diets, has profound effects on both metabolism and brain function, primarily due to its distinct metabolic pathways. …”
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EFFECTS OF ENDOVASCULAR INTERVENTION VS. THROMBOLYSIS ON INTRACARDIAC HEMODYNAMICS AND LEFT VENTRICULAR REMODELLING IN ACUTE MYOCARDIAL INFARCTION by M. Kh. Makoeva, S. P. Semitko, A. G. Avtandilov

“…By Day 7, Group III demonstrated a restrictive type of LV diastolic dysfunction, persistent reduction of ejection fraction, and more pronounced disturbances of local LV contractility, compared to Groups I and II. …”
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The effect of correction of serum level of vitamin D on hyperandrogenism in women with polycystic ovary syndrome and hypovitaminosis D by A. M. Maysara, A. T. Nassar, H. K. Jubran

“…Conclusion: Despite the fact that correction of vitamin D deficiency is important for general health, however it is of limited beneficial effect on the biochemical and clinical parameters of hyperandrogenism in women with PCOS.…”
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Enhancing diabetic rat peripheral nerve conduction velocity parameters through the potent effects of MitoTEMPO by Murat Cenk Celen, Seckin Tuncer, Ahmet Akkoca, Nizamettin Dalkilic

“…Key indicators such as maximum depolarization (MD), CAP area, and conduction velocity distribution (CVD) were measured to gauge MitoTEMPO's neuroprotective effects, alongside physical parameters like weight and blood glucose levels. …”
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The Effect of Overweight/Obesity on Cutaneous Microvascular Reactivity as Measured by Laser-Doppler Fluxmetry: A Systematic Review by Ally McIllhatton, Sean Lanting, Vivienne Chuter

“…Introduction: We sought to determine by systematic review the independent effect of overweight/obesity on cutaneous microvascular reactivity in adults as measured by laser-Doppler fluxmetry. …”
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Cognitive impairment in patients with type 2 diabetes mellitus: prevalence, pathogenetic mechanisms, the effect of antidiabetic drugs by Olga D. Ostroumova, Elena V. Surkova, Evgenia V. Chikh, Ekaterina V. Rebrova, Miron S. Borisov

“…The data demonstrating a multidirectional effect on the cognitive functions of various antidiabetic drugs is presented, the possible influence on the rate of progression of cognitive impairment and the risk of dementia of intensive control of plasma glucose level in comparison with the standard decrease in patients with type 2 diabetes is analyzed.…”
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Effect of Soy Isoflavone on Prostate Cancer Cell Apoptosis Through Inhibition of STAT3, ERK, and AKT by Yoon-Jin Lee, Changyeol Lee, Dongsic Choi, Yeji Lee, Sang-Han Lee

“…Increased reactive oxygen species increased mitochondrial depolarization indicating mitochondrial dysfunction and inhibition of ATP formation were also observed in genistein-treated DU145 cells. …”
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Gardenia-derived extracellular vesicles exert therapeutic effects on dopaminergic neuron apoptosis-mediated Parkinson’s disease by Wen Chen, Haobo Wang, Xiang Ye, Xingkai Hao, Fujie Yan, Jian Wu, Danyang Li, Yan Wang, Lizhou Xu

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Clinical effectiveness of exogenous L-arginine in patients with coronary heart disease after community-acquired pneumonia by T. O. Kulynych

“…The optimization of treatment of comorbid pathology by medicines which modify endothelium functional state is important. Aim: to study effect of exogenous L-arginine on clinical course of disease, markers of systemic inflammation and endothelial dysfunction in patients with coronary heart disease (CHD) and community-acquired pneumonia (CAP). …”
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A pilot study on the effect of severe sleep fragmentation on aorta remodelling, neuroinflammation in a rat model by Perek Nathalie, Guillot Pauline, Mounichetty Chloe, Dumas Virginie, Maia Sylvain, Forest Fabien, Roche Frederic

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Effects of a Total Motion Release (TMR®) Protocol for the Single Leg Squat on Asymmetrical Movement Patterns by Nickolai JP Martonick, Craig P McGowan, Russell T Baker, Lindsay W Larkins, Jeff G Seegmiller, Joshua P Bailey

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Effects of Nigella sativa on VCAM-1 and ICAM-1: A systematic review of preclinical and clinical studies by Zeinab Faghfoori, Zeinab Javadivala, Aida Malek Mahdavi

“…N. sativa seems beneficial in attenuating VCAM-1 and ICAM-1 levels under different situations; however, additional long-term controlled clinical trials are needed for making concise conclusions about the effect of N. sativa on endothelial dysfunction related biomarkers.…”
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Cost-effectiveness of advanced hepatic fibrosis screening in individuals with suspected MASLD identified by serologic noninvasive tests by Huiyul Park, Eileen L. Yoon, Mimi Kim, Ji-hyeon Park, Ramsey Cheung, Jeong-Yeon Cho, Hye-Lin Kim, Dae Won Jun

“…Abstract Our study assessed the cost-effectiveness of screening for hepatic fibrosis in cases suspected of metabolic dysfunction-associated steatotic liver disease (MASLD) using serological noninvasive tests like the fatty liver index (FLI) and hepatic steatosis index (HSI). …”
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Selected traditional Chinese herbal medicines for the treatment of atopic dermatitis - research progress on the effect and mechanism of actions by Lingjie Zhang, Hangjuan Lin, Ninggang Chen, Suyan Zhu, Suyan Zhu, Ying Hu, Ying Hu

“…Due to the complex pathogenesis of AD, its mechanism is primarily associated with genetic, skin barrier dysfunction, environmental, and immune factors. AD has been routinely treated with glucocorticoids, antihistamines, local immunomodulators, biological agents, and small molecules; however, the side effects are significant, and the treatment efficacy is limited. …”
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EFFECT OF SODIUM FLUORIDE ON SOME PHYSIOLOGICAL PARAMETERS AND HISTOPATHOLOGY IN ADRENAL AND THYROID GLANDS IN ADULT MALE RATS by Marwa Adel Hameed, Bader Khatlaan Hameed, Khalid Ahmed Hadi

“…The results of this study confirmed theharmful effect of sodium fluoride(NaF) on thyroid and adrenal functions in addition to its effect onsome biochemical parameters that are indicative of the occurrence of harmful effects of somechemical compounds…”
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Immunomodulatory effects of ulinastatin combined with continuous blood purification in sepsis: a systematic review and meta-analysis by Hui Gao, Zhiqiang Tang, Shucheng Zhao, Yuanjun Zhang

“…BackgroundSepsis involves a dysregulated immune response to infection, causing inflammation and organ dysfunction. This systematic review and meta-analysis evaluated the immunomodulatory effects of ulinastatin combined with continuous blood purification (CBP) in sepsis.MethodsThis study involved a literature search, data extraction, quality assessment, and meta-analysis to evaluate the effects of ulinastatin combined with CBP. …”
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