Pharmacokinetic Properties and Therapeutic Effectiveness of Remimazolam in ICU Patients With Mechanical Ventilation: A Preliminary Study by Jing Hu, Yuhan Zhao, Litao Shao, Wenhui Zhang, Han Wang, Yun Liu, Mengxiang Su, Xiangrong Zuo

“…The pharmacokinetic study indicates that remimazolam is effective and safe for ICU patients on mechanical ventilation, with a 24‐h infusion demonstrating rapid clarence and a clear dose‐effect relationship. …”
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Single cell RNA sequencing reveals the reshaping effect of perfluorooctanoic acid on the intestinal microenvironment of mice by Ya Gao, Jiayun Guan, Rui Zhou, Zewei Li, Tianyang Chen, Kaican Yang, Rong Huang, Yue Huang, Siting Zheng, Zhenhua Huang, Xiaoxiang Rong

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Effectiveness of biofeedback therapy on low anterior resection syndrome: a systemic review with meta-analysis by Jing Zhang, Qin-Bing Zhu, Yu-Sha Zeng, Ya-Hong Xue

“…BackgroundAs a series of bothersome bowel dysfunction symptoms, low anterior resection syndrome (LARS) has a high incidence after rectal cancer surgery, which grievously impairs health-related quality of life. …”
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Protective Effect of Aerobic Training and Royal Jelly on Cellular senescence Markers of Cardiomyocytes in Obese Rats by Iraj Hoseinzade, Ahmad Abdi, Asieh Abbassi Daloii

“…Further investigation is needed for the interactive effect of the AT and RJ.…”
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Neuroprotective, and memory enhancement effects of Salvia aristata and its phenolic constituents: an in vitro, and in vivo study by Farid Dabaghian, Mohammad-Reza Delnavazi, Roshanak Hariri, Tahmineh Akbarzadeh, Zahra Tayarani-Najaran, Mohammad Reza Shams Ardekani, Mohammad Sharifzadeh, Mahnaz Khanavi

“…Abstract Background Alzheimer’s disease (AD) is a progressive neurodegenerative disorder characterized by cholinergic dysfunction, neuroinflammation, oxidative stress, and memory impairment. …”
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Therapeutic Effect of Core Stability Training Combined with Extracorporeal Shock Wave on Lumbar Disc Herniation by Shuo LI, Lishuang LIU, Jinna ZHOU, Qiaoyun XIANG, Tingting LUAN, Wenwen WANG

“…The effective rate was calculated at 3 months of the treatment. …”
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Sex-Dependent Effects of Body Fat on Cardiac Function and Outcomes in Community-Dwelling Older Adults by Haowen Jiang, MBBS, Jie Jun Wong, MBBS, Glades H.M. Tan, BEng, Louis L.Y. Teo, MBBS, See Hooi Ewe, MBBS, PhD, Ru-San Tan, MBBS, Fei Gao, PhD, Angela S. Koh, MBBS, MPH, PhD

“…Background: Among older adults, sex hormones may exert differential effects on body fat and cardiac health. Objectives: The authors aimed to study the effects of sex on body fat composition and aging-related diastolic function, as well as their longitudinal changes. …”
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Effects of external diaphragmatic pacing with neurally adjusted ventilatory assist on diaphragm function in AECOPD patients by Yuliang Sheng, Ting Wang, Xiaohan Zhang, Wei Shao, Yuhao Wang, Xiuwen Kang, Caihong Gu, Yong Li, Zhifang Mu, Chenying Zhang, Rong Hu

“…Abstract Diaphragm dysfunction, a prevalent complication in mechanically ventilated patients, is strongly associated with prolonged weaning periods and increased mortality rates. …”
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Striking Cardioprotective Effects of an Adiponectin Receptor Agonist in an Aged Mouse Model of Duchenne Muscular Dystrophy by Michel Abou-Samra, Nicolas Dubuisson, Alice Marino, Camille M. Selvais, Versele Romain, Maria A. Davis-López de Carrizosa, Laurence Noel, Christophe Beauloye, Sonia M. Brichard, Sandrine Horman

“…Adiponectin (ApN) is a hormone with potent effects on various tissues. We previously demonstrated its ability to counteract Duchenne muscular dystrophy (DMD), a severe muscle disorder. …”
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Stimulant medications effects in heat-related illness in ADHD patients: a large database study by Samrawit Zinabu, Huda Gasmelseed, Noah Wheaton, Fikirte Girma, Christian Wong, Sair Ahmad Tabraiz, Ayesha Mubasher, Aaron Mack, Patrice Lexima, Ozair Qazi, Ahmad Mohammed, Aseem Sood, Miriam Michael, Miriam Michael

“…These medications, while effective, have been associated with thermoregulatory dysfunction and an increased risk of heat-related adverse events. …”
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Effects of PGK1 on immunoinfiltration by integrated single-cell and bulk RNA-sequencing analysis in sepsis by Yu Liu, Weijie Li, Lei Lei, Yaoliang Zhou, Mingcheng Huang, Yide Li, Xiaoying Zhang, Yingyu Jiang, Haiqi Wu, Zhihua Zheng, Kongyang Ma, Chun Tang

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Radiosensitization effect of iridium (III) complex on lung cancer cells via mitochondria apoptosis pathway by Yuru Pang, Qiqi Meng, Yangchen Cui, Shiyi Liu, Huihui Jiang, Chenlan Xu, Yan An, Yang Jiao, Yang Jiao, Qi Zhang, Jihua Nie, Jihua Nie

“…Importantly, these cytotoxic effects were selective, with minimal impact on normal cells. …”
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Mediating Effects of Systemic Inflammation on the Association Between Body Roundness Index and Periodontitis in US Adults by Hui Zhang, Zhengyun Ren, Xi Peng, Tailin Guo

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Neuroprotective Effects of Inhaled Xenon for Sedation Compared With Propofol Intravenous Sedation in Severe Ischemic Stroke by O. A. Grebenchikov, A. K. Evseev, V. V. Kulabuchov, A. N. Kuzovlev, S. S. Petrikov, G. R. Ramazanov, Sh. Gh. Khusainov, R. A. Cherpakov, A. K. Shabanov, A. I. Spichko

“…The paper presents the effect of inhaled xenon for sedation in patients with severe ischemic stroke on the level of consciousness and severity of neurological disorders, and also shows its effect on S100B protein, a marker for blood brain barrier damage.AIM OF STUDY To evaluate the effect of inhaled xenon for sedation in comparison with propofol intravenous sedation on the dynamics of the level of consciousness, the severity of neurological dysfunction and changes in the concentration of astroglial-derived S100B protein in severe ischemic stroke.MATERIAL AND METHODS The research was conducted on two groups of patients comparable in age, gender, comorbid background, as well as the severity of the underlying disease. …”
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Application of acupoint massage combined with Chinese herbal medicine hot compress in nursing of a patient with gastrointestinal dysfunction during mechanical ventilation in ICU (穴... by CHANG Xiaojuan (常晓娟), ZHOU Tingting (周亭亭), WANG Leiyan (王雷彦), WANG Congling (王聪玲), WANG Yilun (王谊伦), WANG Lichan (王立婵), CAO Ebin (曹阿彬)

“…This paper summarized the nursing practice of a patient with gastrointestinal dysfunction during mechanical ventilation in ICU, and investigated the effect of acupoint massage combined with Chinese herbal medicine hot compress in treatment of dysfunction during mechanical ventilation. …”
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Haemodynamic effects of intra‐aortic balloon pumps stratified by baseline pulmonary artery pulsatility index by George Kalapurakal, Vinh Q. Chau, Teruhiko Imamura, Sanika Tolia, Chris Sciamanna, Gregory P. Macaluso, Anjali Joshi, Jessica Pillarella, Sunil Pauwaa, Muhyaldeen Dia, Tarek Kabbany, James Monaco, Mark Dela Cruz, William G. Cotts, Patroklos Pappas, Antone J. Tatooles, Nikhil Narang

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The effect of Zexie decoction on vestibular and auditory function in DDAVP-induced endolymphatic hydrops of Guinea pigs by Renlong Ji, Renlong Ji, Renlong Ji, Yanchang Xu, Yanchang Xu, Yanchang Xu, Kang Li, Kang Li, Kang Li, Wen Jiang, Wen Jiang, Wen Jiang, Yuan Li, Jianwei Zeng, Wei Li, Wei Li, Wei Li, Caiji Wang, Caiji Wang, Caiji Wang, Zeqi Zhao, Zeqi Zhao, Zeqi Zhao, Yalan Li, Naveena Konduru, Naveena Konduru, Naveena Konduru, Wen Liu, Wen Liu, Wen Liu, Wen Liu, Yuehua Qiao, Yuehua Qiao, Yuehua Qiao, Xuanyi Li, Xuanyi Li, Xuanyi Li

“…ObjectiveTo investigate the effects of Zexie decoction on vestibular and auditory function in guinea pigs with endolymphatic hydrolysis induced by desmopressin. …”
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The effect of a water-soluble β-glucan on intestinal immunity and microbiota in LPS-challenged piglets by Yuliang Wu, Yuliang Wu, Yuxin Li, Yuxin Li, Mengli Chen, Mengli Chen, Juan Zhao, Xia Xiong, Xia Xiong, Xia Xiong, Chen Guang Olnood, Yundi Gao, Fei Wang, Can Peng, Can Peng, Miao Liu, Miao Liu, Chunxia Huang, Jianzhong Li, Liuqin He, Huansheng Yang, Yulong Yin, Yulong Yin, Yulong Yin

“…A water-soluble β-glucan produced by Agrobacterium ZX09 has been shown to have a beneficial effect on gastrointestinal health. The main objective of this study was to investigate whether pre-feeding β-glucan has a protective effect on LPS-induced immune stress in piglets. …”
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EVALUATION OF THE EFFECTIVENESS OF TREATMENT OF CHRONIC CATARRHAL GINGIVITIS IN CHILDREN WITH DIABETES MELLITUS IN LONG-TERM OBSERVATIONS by L.F. Kaskova, V.A. Honcharenko

“…The aim of the study. To evaluate the effectiveness of the proposed treatment method for children with chronical catarrhal gingivitis and diabetes mellitus. …”
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Ejercicio Físico es efectivo para la rehabilitación de la presión y rigidez arterial en adultos con hipertensión (Exercise training is effective for arterial stiffness and blood pr... by Cristian Alvarez, Luis Peñailillo, Paulina Ibacahe, Marcelo Tuesta, Daniel Jerez-Mayorga, Jaroslaw Domaradski, David C. Andrade, Omar Andrade-Mayorga, Johnattan Cano-Montoya, Pedro Delgado-Floody

“…Keywords: Arterial hypertension; Endothelial dysfunction; Pulse wave velocity; Augmentation index; Ankle brachial index.   …”
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