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Renoprotective Effects of the Dipeptidyl Peptidase-4 Inhibitor Sitagliptin: A Review in Type 2 Diabetes
Published 2017-01-01Get full text
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2863
Interventions targeting the gut microbiota and their possible effect on gastrointestinal and neurobehavioral symptoms in autism spectrum disorder
Published 2025-12-01“…The modulation of the gut microbiota using MTT in ASD has shown beneficial and long-term effects on GI symptoms and core symptoms of autism. …”
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Activation of Nrf2 pathway by 4-Octyl itaconate enhances donor lung function in cold preservation settings
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Current therapy of the right ventricle myocardial infarction
Published 2002-01-01Get full text
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BAM8-22 targets spinal MrgC receptors to modulate UPRmt activity in the mechanism of bone cancer pain
Published 2025-03-01“…Cellular energy metabolism homeostasis is critically dependent on mitochondrial integrity, and emerging evidence suggests that mitochondrial dysfunction in chronic BCP exacerbates pain progression by disrupting nociceptive signaling pathways. …”
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Approaches to early diagnosis and prevention of cardiovascular toxicity induced by targeted drugs and immune checkpoint inhibitors in oncohematology: a literature review
Published 2023-02-01“…The spectrum of cardiovascular adverse effects associated with targeted and ICI therapy in oncohematological practice is quite wide — coronary artery disease, peripheral arterial disease, myocarditis, heart failure, arrhythmias, hypertension. …”
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Caffeine ameliorates metabolic-associated steatohepatitis by rescuing hepatic Dusp9
Published 2025-03-01“…However, the therapeutic effects of CAFF on metabolic-associated steatohepatitis (MASH) and the underlying mechanisms remain unclear. …”
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Focused radiofrequency treatment of postpartum vaginal relaxation syndrome
Published 2020-10-01“…The data obtained by us demonstrate positive effects after using monopolar radiofrequency therapy on the tissues in the vulva, vagina and perineum of patients in the postpartum period. …”
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Hydroxysteroid 17β‐dehydrogenase 13 (Hsd17b13) knockdown attenuates liver steatosis in high‐fat diet obese mice
Published 2025-08-01“…Abstract Hydroxysteroid 17β‐dehydrogenase 13 (HSD17B13) loss‐of‐function gene variants are associated with a decreased risk of metabolic dysfunction‐associated steatotic liver disease (MASLD). …”
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Antidiabetic and TNF-α Lowering Effect of Tagetes erecta Extract in Alloxan-Induced Diabetic Rats
Published 2025-05-01“…Furthermore, the highest dose of T. erecta extract (75 mg/kg BW) effectively attenuated elevated TNF-α levels, demonstrating a significant anti-inflammatory effect. …”
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Effects of Pelvic Floor Muscle Exercises on Sexual Function in Postmenopausal Women - a Systematic Review
Published 2025-02-01“…Background: Hormonal changes associated with menopause, often lead to the development of sexual dysfunctions in women. These include lowering of the reproductive organs, urinary incontinence, recurrent infections and hormonal changes. …”
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Effects of Human Umbilical Cord Mesenchymal Stem Cells on Human Trophoblast Cell Functions In Vitro
Published 2016-01-01“…Trophoblast cell dysfunction is involved in many disorders during pregnancy such as preeclampsia and intrauterine growth restriction. …”
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Additive effect of diabetes mellitus on the prevalence and prognosis of sarcopenic obesity: Implications for all-cause mortality.
Published 2025-01-01“…Sarcopenic obesity, characterized by reduced muscle mass and increased adiposity, contributes to physical frailty and metabolic dysfunction. This study investigated the effect of DM on mortality rates and causes of death among individuals with high adiposity and low muscle mass (HA-LM) by using data from the National Health and Nutrition Examination Survey (NHANES) linked to mortality records from 2011 to 2018. …”
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Research progress on the effect of muscle satellite cells on anal sphincter repair in neurogenic fecal incontinence
Published 2024-08-01“…Neurogenic fecal incontinence refers to the dysfunction of anal sphincter contraction caused by degenerative atrophy of the anal sphincter secondary to pudendal nerve injury, manifested as involuntary leakage of feces from the anus. …”
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Effect and Mechanism of TFAM on Chemotherapy Resistance in Ovarian Cancer Cells Through Metabolic Reprogramming Regulation
Published 2025-05-01“…A TFAM-overexpressing cell model was established to assess its effects on platinum sensitivity, mitochondrial function, and aerobic glycolysis; and glycolytic enzyme and drug-resistant protein expression were analyzed. …”
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Effects of SLC6A8 mutation-induced creatine deficiency on cellular function in fibroblasts
Published 2025-07-01Get full text
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Effect of Subtalar Joint Mobilization and Myofascial Trigger Point Release on Pain and Disability in Plantar Fasciitis
Published 2025-01-01“…Risk factors include limited dorsiflexion excessive plantar flexion foot pronation prolonged weight-bearing high body mass index subcalcaneal spurs and subtalar joint dysfunction. The fascias role in stabilizing body structures is vital for addressing this condition. …”
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Research Progress on the Protective Effects of Active Components of Huangqi (Astragali Radix) on Pancreatic β-Cells
Published 2025-06-01“…The potential application of Huangqi (Astragali Radix) in the treatment of diabetes mellitus (DM) has garnered increasing attention. β-cell dysfunction is one of the core mechanisms in the pathogenesis of DM and effectively protecting and restoring pancreatic β-cell function remains a key challenge in DM prevention and treatment. …”
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