Estrogen administration enhances the adverse effects of cigarette smoking on the heart in cycling female mice by Emna Abidi, Reine Diab, Rana Zahreddine, Ghadir Amin, Abdullah Kaplan, George W. Booz, Fouad A. Zouein

“…CS induces oxidative stress and endothelial dysfunction, which has a profound impact on cardiac structure and function. …”
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Gastrin exerts a protective effect against myocardial infarction via promoting angiogenesis by Jinjuan Fu, Yuanjuan Tang, Zhen Zhang, Lin Tong, Rongchuan Yue, Lin Cai

“…Results We found that gastrin administration significantly ameliorated MI-induced cardiac dysfunction and reduced fibrosis at 28 days in post-MI hearts. …”
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Nrf2-dependent effects of CDDO-Me on bactericidal activity in macrophage infection models by Therese B. Deramaudt, Ahmad Chehaitly, Marcel Bonay, Marcel Bonay

“…Dysregulated macrophage activity and excessive oxidative stress exacerbate immune dysfunction and inflammation in these conditions. Nrf2 (nuclear factor erythroid 2–related factor 2) is a key regulator of antioxidant defenses and macrophage function. …”
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EVALUATING THE EFFECTIVENESS OF TRANSPLANTATION CARE TO THE PATIENTS WITH END-STAGE HEART FAILURE IN SVERDLOVSK REGION by N.F. Klimusheva, E.M. Idov, A.I. Iofin, A.L. Levit, I.Y. Serebryakov, Y.A. Zavershinsky, A.N. Bykov, A.A. Piontek

“…Heart transplantation is an effective treatment for end-stage heart failure.…”
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In-vivo antioxidant and therapeutic effects of ellagic acid on ischemia-reperfusion injury in skeletal muscle by Huseyin Demirtas, Abdullah Ozer, Dilara Yigit, Ali Dogan Dursun, Zeynep Yigman, Cagla Kosa, Aysegul Kucuk, Elif Simsek, Mustafa Arslan

“…Aim: Skeletal muscle ischemia-reperfusion (IR) injury is a critical clinical issue characterized by oxidative stress, inflammation, and tissue damage, potentially leading to systemic organ dysfunction. Ellagic acid (EA), a naturally occurring polyphenolic compound, is widely recognized for its strong antioxidative, anti-inflammatory, and antiapoptotic effects demonstrated in various preclinical studies. …”
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The Effects of Botulinum Toxin A Injections on Patients with Radiogenic Lower Urinary Tract Symptoms by Anke K. Jaekel, Ann-Christin Brüggemann, John Bitter, Franziska Knappe, Ruth Kirschner-Hermanns, Stephanie C. Knüpfer

“…Botulinum toxin A (BTX-A) injection into the detrusor vesicae is an established therapy for neurogenic lower urinary tract dysfunction as well as idiopathic overactive bladder. …”
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Dose-dependent renoprotective effects of sacubitril/valsartan in heart failure: a retrospective study by Takahiro Kato, Yusuke Nakano, Noriko Yasukawa, Masafumi Oonishi, Yukihiro Hamada

“…SV exhibits dose-dependent renoprotective effects in heart failure patients. Optimizing SV dosage may be beneficial for heart failure patients with concurrent kidney dysfunction, especially those with proteinuria.…”
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Clinical effectiveness of eprosartan and hydroxyzine in patients with mild to moderate arterial hypertension and coexisting anxiety by G. V. Pogosova, E. E. Koltunov, E. Yu. Spivak, Yu. S. Belova, A. V. Karpova

“…То evaluate clinical effectiveness of eprosartan and hydroxyzine in patients with mild to moderate arterial hypertension (AH) and coexisting anxiety.Material and methods. …”
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Radiosensitizing effects of pyrogallol-loaded mesoporous or-ganosilica nanoparticles on gastric cancer by amplified ferroptosis by Hongwei Wang, Hongwei Wang, Hongyan Niu, Xi Luo, Nan Zhu, Jingfeng Xiang, Yan He, Zhian Chen, Guoxin Li, Yanfeng Hu

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Effect of Donor Sperm on Quality of Life in Patients with Severe Oligoasthenosperm After ICSI Failure by Wang K, Xu Y, Qin N, Guo Y, Bai J, Li Z

“…The total score of FertiQoL and PSQI in the observation group were higher than those in the control group, and the incidence of erectile dysfunction was higher than that in the control group, with statistical significance (P< 0.05).Conclusion: The use of donor sperm for pregnancy after ICSI failure in patients with severe oligoasthenospermia has a great impact on their reproductive life, sleep quality and erectile function. …”
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Effect of preoperative alpha‐blockers on ureteroscopy outcomes: A meta‐analysis of randomised trials by Naeem Bhojani, Ben H. Chew, Samir Bhattacharyya, Amy E. Krambeck, Khurshid R. Ghani, Larry E. Miller

“…Alpha‐blockers increased ejaculatory dysfunction risk and were less effective for renal/proximal ureter stones. …”
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Acute Kidney Injury in Patients After Cardiac Arrest: Effects of Targeted Temperature Management by Silvia De Rosa, Sergio Lassola, Federico Visconti, Massimo De Cal, Lucia Cattin, Veronica Rizzello, Antonella Lampariello, Marina Zannato, Vinicio Danzi, Stefano Marcante

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Effects of Moringa oleifera leaves on CRP, MDA, and alevels in a mouse model of preeclampsia by Nutria Widya Purna Anggraini, Sri Sulistyowati, Soetrisno Soetrisno, Bambang Purwanto, Paramasari Dirgahayu

“…Background: Preeclampsia is a serious pregnancy complication characterized by high blood pressure and organ dysfunction, primarily affecting the placenta and kidneys. …”
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The Protective Effect of Mangiferin on Formaldehyde-Induced HT22 Cell Damage and Cognitive Impairment by Fan Chen, Na Wang, Xinyan Tian, Juan Su, Yan Qin, Rongqiao He, Xiaping He

“…The present study was designed to characterize the effects and mechanisms by which MGF protects against FA-induced neurotoxicity. …”
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Effects of cannabidiol (CBD) treatment on age-related cognitive decline in C57 mice by Behroo Mirza Agha, Merrin Monteith, Jarem Earl, Keona Ganske, Tina Kaloa, Kelan J. McDonald, Abigail G. Nixon, Maleeha Panjwani, Danika Robinson, Valeria Rusnak, Majid H. Mohajerani, Igor Kovalchuk, Robert J. Sutherland, Nancy S. Hong, Robert J. McDonald

“…This study investigates the effects of cannabidiol (CBD) on memory impairment and brain inflammation in aging mice. …”
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Effects of noradrenaline and phenylephrine on cerebral oxygen saturation during cardiopulmonary bypass in cardiac surgery by Edouard Marques, Etienne J. Couture, Jean S. Bussières, Stephan Langevin, Paul Poirier, Pierre Voisine, Manon Caouette, Patrice Brassard

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SIRT1-dependent mechanisms and effects of resveratrol for amelioration of muscle wasting in NASH mice by Chang-Youh Tsai, Tzu-Hao Li, Ying-Ying Yang, Chia-Chang Huang, Chih-Wei Liu, Ming-Wei Lin, Ming-Chih Hou, Yi-Hsiang Huang, Chien-Fu Hsu, Yu-Lien Tsai, Hung-Cheng Tsai, Shiang-Fen Huang, Yun-Cheng Hsieh, Tzung-Yan Lee, Han-Chieh Lin

“…In vitro, resveratrol alleviated palmitate acid-induced oxidative stress, lipid deposition, autophagy dysfunction, apoptotic signals, and subsequently reduced fusion index and myotube formation of C2C12 cells. …”
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Therapeutic effects of PDGF-AB/BB against cellular senescence in human intervertebral disc by Changli Zhang, Martha Elena Diaz-Hernandez, Takanori Fukunaga, Sreekala Shenoy, Sangwook Tim Yoon, Lisbet Haglund, Hicham Drissi

“…While previous studies have highlighted that platelet-derived growth factor (PDGF) mitigated IVD degeneration through anti-apoptotic and pro-anabolic effects, its impact on IVD cell senescence remains elusive. …”
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Effects of Age and Sex on Systemic Inflammation and Cardiometabolic Function in Individuals With Type 2 Diabetes by Jody Dushay, Eva S. Rickers, Enya Wang, Jessica Gilman, Ying Zhang, Ron Blankstein, Ernest V. Gervino, Michael Jerosch‐Herold, Aristidis Veves

“…Background Systemic inflammation, aging, and type 2 diabetes (T2D) lead to varying degrees of cardiovascular dysfunction and impaired aerobic exercise capacity. …”
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Discontinuation rates, clinical effects and provocation factors of SGLT-2 inhibitor in the real world by Minjung Bak, Sang Ah Chi, Kina Jeon, David Hong, Heayoung Shin, Darae Kim, Jin-Oh Choi

“…Despite the recognized effectiveness of SGLT-2 inhibitors, there remains a paucity of research on the discontinuation of these medications. …”
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