The effect of physical exercise on cardiopulmonary fitness in burn patients: A meta-analysis. by Da Huang, XiaoXiang Wan, Juan Xu

“…<h4>Objective</h4>Cardiopulmonary dysfunction in burn patients is typically caused by both the burn injury and smoke inhalation. …”
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Molecular insight into reproductive toxicity and transgenerational effects of Cadmium exposure on Drosophila melanogaster by Yi Pan, Ke Fan, Linhao Zong, Yantao Luo, Xin Ni, Dong Chen, Jinjun Qian, Fei Ma, Jie Cheng, Miao Guan

“…Secondly, sustained detrimental effects were observed for at least two to three generations after Cd removal. …”
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Multidirectional therapeutic effects of synthesized HMGB1 peptide on liver cirrhosis in mice by Masaki Mito, Atsunori Tsuchiya, Soichi Ishii, Takafumi Tonouchi, Kaito Furuyama, Ryo Jinbo, Nobutaka Takeda, Hiroyuki Abe, Katsuto Tamai, Shuji Terai

“…Aim: Liver cirrhosis is a serious disease characterized by liver dysfunction and severe fibrosis; however, no breakthrough drugs have effectively improved fibrosis, making it an unmet medical need. …”
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Effect of continuous quality improvement on protein energy wasting in maintenance dialysis patients by Chai Lu, Zhang Ying-zi, Liu Jin-hong, Hu Hong

“…Objective To explore the effect of continuous quality improvement（CQI）on protein energy wasting（PEW）in maintenance hemodialysis patients.Methods From July 2016 to June 2017,85 PEW patients undergoing routine hemodialysis at blood purification center were selected.Through the establishment of CQI team and the application of CQI program, the management objects included patients, their families and implementing "PDCA"（plan, do, check & act）during treatment.The observation period lasted 12 months.Serum albumin（Alb）,serum prealbumin（PA）,transferrin（TF）and serum cholesterol（serum）before and after CQI were compared cholesterol Tch, hemoglobin（Hb）,serum creatinine（Scr）,urea nitrogen（BUN）,serum hypersensitive C-reactive protein（hs CRP）,body mass index（BMI）,normalized protein catabolic rate（nPCR）,mid arm circumference（MAC）and mid arm circumference（MAMC）were measured.Serum calcium, phosphorus, parathyroid hormone（iPTH）and modified quantitative and global assessment（MQSGA）were recorded.And the impact of CQI on these indicators was observed.Results After CQI,the average levels of Alb（g/L）,PA（mg/L）,TF（mg/L）,Tch（mmol/L）,Hb（g/L）and BMI（kg/m²）were markedly higher than before（34.34±3.97 vs 37.26±3.33,252.9±41.7 vs 295.1±39.0,1.52±0.24 vs 1.99±0.25,2.93±0.84 vs 4.23±0.97,83.88±16.75 vs 94.12±13.46,27.58±6.84 vs 28.16±5.78,P<0.05）.The average level of hs CRP decreased from（20.85±2.09）to（13.15±1.74）mg/L（t=5.02,P<0.01）,MAC increased from（22.02±1.63）to（24.81±1.26）mm（t=5.02,P<0.01）and MAMC rose from（20.68±1.47）to（22.74±1.40）mm（t=2.603,P=0.017）,nPCR increased from（0.85±0.92）g·kg^-1·d^-1 to（1.21±0.21）g·kg^-1·d^-1（t=1.154,P=0.022）,mild proportion increased from 77.65% to 88.23%（χ²=4.61,P=0.002）,moderate proportion declined from 18.82% to 10.59%（χ²=3.69,P=0.017）and severe proportion dropped from 3.5% to 1.33%（χ²=5.05,P<0.001）.The average level of serum calcium showed little change（t=0.629,P=0.537）,proportion of attaining the standard spiked from 52% to 66.7%（χ²=2.36,P<0.05）;average level of blood phosphorus decreased from（2.11±0.24）to（1.80±0.23）mmol/L（t=-0.459,P<0.05）,average level of iPTH declined from（40.79±18.67）to（24.41±9.82）pmol/L（t=-5.566,P<0.001）and proportion of reaching the standard jumped from 47.62% to 71.43%（χ²=4.69,P<0.001）.Conclusion CQI can significantly improve the comprehensive nutritional status of patients and the proportion of patients with blood calcium, blood phosphorus and iPTH compliance has significantly improved.There is no occurrence of calcium and phosphorus metabolism disorder or secondary parathyroid dysfunction.…”
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Transcriptomic analysis of the toxic effects and potential mechanisms of fenvalerate on the liver of Odontobutis potamophila by Guoxing Liu, Tian Zhu, Zihan Zhou, You Zheng, Yanhua Zhao, Chen Hao, Shuyan Ding, Xiuhui Tan, Qichen Jiang

“…In summary, this study revealed that the toxic effects of FEN on the liver of O. potamophila manifested as causing oxidative stress, resulting in tissue damage and mitochondrial dysfunction, and its key pathway of action is retrograde endocannabinoid signaling pathway. …”
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The decline of male sexual activity and function after surgical treatment for rectal cancer by Anne Thyø, Peter Christensen, Ismail Gögenur, Marianne Krogsgaard, Michael B. Lauritzen, Birgitte S. Laursen, Anette H. Mikkelsen, Asbjørn M. Drewes, Therese Juul

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Research progress on the regulation of signal pathways related to lung injury in sepsis by the active components of traditional Chinese medicine by RONG Jilintai*，SU He，ZHANG Ruifen，ZHANG Hairong，JIA Tingting，GUO Sihan，ZHAO Jian，LI Xiao，ZHONG Xin

“…Sepsis is a systemic inflammatory response syndrome caused by infection，with resulting organ dysfunction being the key factor in mortality. The lung is one of the organs most frequently affected by sepsis. …”
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Adherence to a “MediterrAsian” diet is associated with weight loss-independent improvements in liver fat and lipid profile, but not glucoregulation or inflammation: secondary analy... by Yu Chung Chooi, Faidon Magkos, Jadegoud Yaligar, Navin Michael, Suresh Anand Sadananthan, Yeshe Manuel Kway, Yeshe Manuel Kway, S. Sendhil Velan, Kevin Junliang Lim, Xianning Lai, Long Hui Wong, Yap Seng Chong, Yap Seng Chong, Evelyn Xiu Ling Loo, Evelyn Xiu Ling Loo, Johan G. Eriksson, Johan G. Eriksson, Johan G. Eriksson, Johan G. Eriksson

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The association of chronic pain, painkiller use, and potential mediators with liver fat content by Yu Cheng, Rong Yang, Yu Jia, Yiheng Zhou, Yi Yao, Can Shen, Dongze Li, Rui Zeng, Zhi Wan, Qian Zhao, Lihua Jiang, Xiaoyang Liao

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USP29 alleviates the progression of MASLD by stabilizing ACSL5 through K48 deubiquitination by Sha Hu, Zhouxiang Wang, Kun Zhu, Hongjie Shi, Fang Qin, Tuo Zhang, Song tian, Yanxiao Ji, Jianqing Zhang, Juanjuan Qin, Zhigang She, Xiaojing Zhang, Peng Zhang, Hongliang Li

“…Background/Aims Metabolic dysfunction–associated steatotic liver disease (MASLD) is a chronic liver disease characterized by hepatic steatosis. …”
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Global research trends in Chinese medicine for the treatment of non-alcoholic fatty liver disease (NAFLD): A bibliometric study by Kangjie li, Jie Wang, Ming Dang, Runxin Ren, Maomao Fu, Jing Wang, Qiao Zhang, Chongbo Zhao

“…The anti-inflammatory effects primarily result from the inhibition of inflammatory signaling pathways. …”
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Cellular and Molecular Mechanisms Explaining the Link Between Inflammatory Bowel Disease and Heart Failure by Arveen Shokravi, Yuchen Luo, Simon W. Rabkin

“…Additional contributing factors include endothelial and microvascular dysfunction, autonomic dysregulation, nutritional deficiencies, shared genetic susceptibility, and adverse pharmacologic effects. …”
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Enhancing Hand Sensorimotor Function in Individuals with Cervical Spinal Cord Injury: A Novel Tactile Discrimination Feedback Approach Using a Multiple-Baseline Design by Ken Kitai, Kaichi Nishigaya, Yasuhisa Mizomoto, Hiroki Ito, Ryosuke Yamauchi, Osamu Katayama, Kiichiro Morita, Shin Murata, Takayuki Kodama

“…<b>Background/Objectives</b>: This study evaluated the effects of a tactile-discrimination compensatory real-time feedback device on hand sensorimotor function in cervical spinal cord injury patients. …”
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THERAPEUTIC EYELIDS HYGIENE IN THE ALGORITHMS OF PREVENTION AND TREATMENT OF OCULAR SURFACE DISEASES. PART II by V. N. Trubilin, E. G. Poluninа, E. Y. Markova, V. V. Kurenkov, S, G. Kapkova

“…Objective evidence of relevance and effectiveness of therapeutic care age, in our opinion, is the rapid development of the pharmaceutical market in this area. …”
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Adherence to the Mediterranean diet to prevent or delay hepatic steatosis: a longitudinal analysis within the PREDIMED study by Raquel Cueto-Galán, Raquel Cueto-Galán, Andres Fontalba-Navas, Andres Fontalba-Navas, Andres Fontalba-Navas, Mario Gutiérrez-Bedmar, Mario Gutiérrez-Bedmar, Mario Gutiérrez-Bedmar, Miguel Ruiz-Canela, Miguel Ruiz-Canela, Miguel A. Martínez-González, Miguel A. Martínez-González, Miguel A. Martínez-González, Lilian Alves, Nancy Babio, Nancy Babio, Nancy Babio, Montserrat Fitó, Montserrat Fitó, Emilio Ros, Emilio Ros, Miquel Fiol, Miquel Fiol, Ramón Estruch, Ramón Estruch, Fernando Arós, Fernando Arós, Luis Serra-Majem, Luis Serra-Majem, Xavier Pintó, Xavier Pintó, Carlos Muñoz-Bravo, Carlos Muñoz-Bravo, Antonio García-Rodríguez, Antonio García-Rodríguez, Enrique Gómez-Gracia, Enrique Gómez-Gracia

“…BackgroundLittle is known about the potential preventive effect of adherence to the Mediterranean diet (MedDiet) on the development of metabolic dysfunction-associated steatotic liver disease (MASLD).AimThis study aims to determine the impact of adherence to the MedDiet on the progression of MASLD, measured using the hepatic steatosis index (HSI) at baseline and annually over a 5-year follow-up period within the framework of the PREvención con DIeta MEDiterránea (PREDIMED) study.MethodParticipants from the PREDIMED trial with sufficient available data (n = 3,145) were examined annually over 5 years. …”
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Association between Helicobacter pylori seropositivity and the hemoglobin A1c/high-density lipoprotein cholesterol ratio in U.S. adults: evidence from NHANES by Cheng Xu, Cheng Xu, Xin-yi Jiang, Xin-yi Jiang, Jia-ming Liao, Jia-ming Liao, Yi-fan Zhao, Yi-fan Zhao, Jing-yi Hu, Chong-Chao Li, Hong Shen

“…Generalized additive models with smoothing splines and threshold effect analysis was conducted to identify potential nonlinear relationships.ResultsThe cross-sectional analysis comprised 2,909 participants, including 1,254 with H. pylori seropositivity. …”
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Integrated Multiomics Analyses of the Molecular Landscape of Sarcopenia in Alcohol‐Related Liver Disease by Nicole Welch, Pugazhendhi Kannan, Saurabh Mishra, Annette Bellar, Vandana Agrawal, Grahame Kidd, Emily Benson, Ryan Musich, Raya Tabbalat, Ling Li, J. Mark Brown, Belinda Willard, Karyn A. Esser, Laura E. Nagy, Srinivasan Dasarathy

“…These findings show the complex molecular interactions leading to mitochondrial dysfunction and progressive sarcopenia in ALD.…”
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Efficacy of brief cognitive behavior therapy in improving symptoms, functioning, and adherence to treatment in patients with bipolar disorder in remission: A randomized control stu... by Seema Nambiar, Manjula Munivenkatappa, Shyam Sundar Arumugham

“…Larger within group effect sizes for anxiety, dysfunctional attitudes and emotion regulation, medium effect sizes for depression, and quality of life and small effect sizes for manic symptoms and medication adherence were found in the intervention group. …”
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Effective management of pediatric septic shock: a case study utilizing continuous renal replacement therapy with cytosorb and citrate in a leukemic patient with hyper-interleukin (... by Amir Saeed, Hadis Jafarian, Ali Amanati

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Dry Eye After Clear Cornea Phacoemulsification by Peter Mark G. Chao, MD, Ruben Lim Bon Siong, MD

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