Exploring the Causal Effect of Mitochondrial DNA Copy Number on Obstructive Sleep Apnea by Ping Ji, Yujiang Fan, Junling Li, Zhaoan Deng, Guofu Zhang, Jianbin Du

“…Improving mitochondrial dysfunction may help prevent or treat OSA.…”
Get full text

Deferential nephrotoxicity effect of lanthanum oxide nanoparticle responses to concentration and time in vivo by Nouf M. Alyami, Ghufran A. Almuhaini, Hussah Alobaid, Saleh Maodaa, Noura M. Alshiban, Zainab Ali Alnakhli, Faten Jamal Alashkar, Khalid Elfaki Ibrahim, Saeed Alqahtani, Rafa Almeer, Hanadi M. Alyami, Saud Alarifi

“…A strong positive relationship was found between the inflammatory marker NOS2 transcription and NP dose, confirming pro-inflammatory effects based on concentration. Significant elevations, particularly at lower NP doses, were observed with KIM-1, uric acid, urea, ALP, ALT, and AST, indicating kidney and liver dysfunction. …”
Get full text

CARDIOPRODUCTIVE EFFECTS OF EXXENATE AMID AND VILDAGLIPTIN INCRETIN MIMETICS IN DOXYRUBRICINE CARDIOMYOPATHY MODELING by A. P. TARASOVА, A. V. KHAVANSKY, A. S. TIMOKHINA, A. P. DOVGAN, D. A. KOSTINA, L. N. SERNOV

“…The results show that the exenatide (10 μg/kg/day) and vildagliptin (0.2 mg/kg/day) incretin mimetics show a cardioprotective effect on the doxyrubicin pathology model, which is expressed in a decrease in the coefficient of diastolic dysfunction (StTTI), respectively, to 5.3±0.1 cu and 6.5±0.2 cu compared with the control group 8.3±0.1 cu.Conclusion. …”
Get full text

Case Report: Effect of testicular adenomatoid tumors on testicular endocrine function in children by Yan Li, Junfeng Zhao, Yi Chen, Jing Zhang, Hehe Chen

Get full text

Acute Effect of a Single Functional Neurology Intervention on Muscular Trigger Point by Jorge Rey-Mota, Guillermo Escribano-Colmena, Athanasios A. Dalamitros, Rodrigo Yáñez-Sepúlveda, David Martín-Caro Álvarez, Eduardo Navarro Jimenez, Vicente Javier Clemente-Suárez

“…Background: Myofascial trigger points (MTrPs) are hyperirritable spots in skeletal muscle associated with pain and dysfunction, often impacting individuals’ quality of life. …”
Get full text

Cardioprotective effects of CoQ10 in pediatric patients with lysosomal storage disorders by Yasmine Abuzaid, Ghada Abdul Moemn Suliman, Osama Abd Rab El Rasool Toulba, Ahmed Abd El Basset Abo Elezz, Alshimaa Badraldeen, Heba Dawoud

“…The aim of this study: was to study the possible effects of Coenzyme Q10 as a cardioprotective and an antioxidant drug in patients with LSDs. …”
Get full text

Hydrogen-Rich Water to Enhance Exercise Performance: A Review of Effects and Mechanisms by Qiaorui Zhou, Huixin Li, Ye Zhang, Yirui Zhao, Can Wang, Chang Liu

“…<b>Results</b>: It highlights HRW’s effects on various aspects of athletic performance, including endurance, strength, sprint times, lunge movements, countermovement jump height, and time to exhaustion. …”
Get full text

The Effect of Sex Differences on Endothelial Function and Circulating Endothelial Progenitor Cells in Hypertriglyceridemia by Zi Ren, Jiayi Guo, Xingxing Xiao, Jiana Huang, Manchao Li, Ruibin Cai, Haitao Zeng

Get full text

Postprandial Composite Biomarkers of Low-Grade Inflammation to Evaluate Nutritional Intervention Effects by Suzan Wopereis, Willem J. van den Brink, Tim J. van den Broek, Wilrike J. Pasman, Femke P. M. Hoevenaars

“…Background and objectives: Low-grade inflammation, a hallmark of metabolic disorders, originates in tissues as a consequence of metabolic dysfunction before it progresses to systemic manifestation. …”
Get full text

Protective Effects of HBSP on Ischemia Reperfusion and Cyclosporine A Induced Renal Injury by Yuanyuan Wu, Junlin Zhang, Feng Liu, Cheng Yang, Yufang Zhang, Aifen Liu, Lan Shi, Yajun Wu, Tongyu Zhu, Michael L. Nicholson, Yaping Fan, Bin Yang

“…Ischemia reperfusion (IR) and cyclosporine A (CsA) injuries are unavoidable in kidney transplantation and are associated with allograft dysfunction. Herein, the effect and mechanism of a novel tissue protective peptide, helix B surface peptide (HBSP) derived from erythropoietin, were investigated in a rat model. …”
Get full text

Effect of tocilizumab on pulmonary gas exchange function in patients with severe COVID-19 by D. A. Lebedev, Yu. Kh. Dolya, G. E. Savkov, M. A. Godkov, E. V. Klychnikova, А. P. Shakotko, D. A. Kosolapov, S. N. Kuznetsov, A. M. Kvasnikov, Yu. N. Vrabiy, K. V. Kiselev, V. B. Poluektova, S. S. Petrikov, K. A. Popugaev

“…COVID-19 causes cytokine storm and acute respiratory distress syndrome, which can lead to severe lung damage and multiple organ dysfunction. Early use of monoclonal antibodies has shown promising results in cytokine storm therapy, but the effects on lung gas exchange function have not yet been studied.Aim. …”
Get full text

Effect of Propolis on PPP2R1A and Apoptosis in Cancer Cells by Burak Durmaz, Latife Merve Oktay Çelebi, Ayşe Çekin, Ayshan Ahadova, Nur Selvi Günel, Hatice Kalkan Yıldırım, Ali Mert Özgönül, Eser Yıldırım Sözmen

“…Although many research studies observed antitumor effect of propolis extracts in various types of cancer, the mechanism of effect are still obscure. …”
Get full text

Effects of coenzyme q10 supplementation on metabolic and reproductive outcomes in obese rats by Gisela Belén Sarrible, María Victoria Bazzano, Caterina Koutsovitis, María Guillermina Bilbao, Rodrigo Hernán Da Cuña, Melanie Neira, Julián Alberto Bartolomé, Evelin Mariel Elia

“…CoQ10 administration showed beneficial effects on all ovarian disruptions but had no effect on the metabolic alterations induced by obesity. …”
Get full text

CLINICAL EVALUATION OF THE EFFECTIVENESS OF MEDICATIONS NEUROTRANSMITTER ACTIONS IN THE TREATMENT OF PATIENTS WITH PRIMARY GLAUCOMA by I. A. Zakharova, R. V. Avdeev, V. A. Pristavka, S. N. Surnin, V. Y. Mahmutov, I. I. Savrasova

“…Aim was to study the effectiveness of neuromedin in the treatment of patients with primary glaucoma with compensated intraocular pressure (IOP). patients and methods. …”
Get full text

The effects of coconut oil intake on metabolic disorders and fatty liver disease in mice by Madoka Sumi, Yuka Hasegawa, Tomoyuki Matsuyama, Tomoki Miyoshi, Hanako Nakajima, Takuro Okamura, Naoko Nakanishi, Ryoichi Sasano, Masahide Hamaguchi, Michiaki Fukui

“…This study aimed to evaluate the effects of medium-chain fatty acids derived from coconut oil on metabolic disorders, particularly fatty liver, using a mouse model established by a high-fat diet. …”
Get full text

Cardioprotective effects of the estrogen receptors modulators in the conditions of experimental acute myocardial infarction by K. V. Levchenko, S. V. Gorbachova

“…Interaction of these effects of tamoxifen citrate in conditions of acute myocardial infarction modelling resulted in a marked cardioprotective effect, increasing the percentage of animals which survived to an average of 75 %. …”
Get full text

Effect of the Nrf2/HO-1 pathway on aluminum-induced liver injury by Xi Wei, Yueling Luo, Dongjie Yuan, Dong Li, Yixi Nong, Biaoliang Wu, Xiaojie Qin

“…The results showed that Al accumulation in liver tissue led to rat histopathological changes and liver dysfunction, promoting oxidative stress and hepatocyte apoptosis, while also enhancing Nrf2/HO-1-associated protein levels. …”
Get full text

The Hidden Impact of Gestational Diabetes: Unveiling Offspring Complications and Long-Term Effects by Elsa Al Bekai, Carla El Beaini, Karim Kalout, Ouhaila Safieddine, Sandra Semaan, François Sahyoun, Hilda E. Ghadieh, Sami Azar, Amjad Kanaan, Frederic Harb

“…Practical Implications: Understanding the intergenerational effects of GDM has important clinical implications for prenatal and postnatal care. …”
Get full text

Effects of a 24-week yoga intervention on choriocapillaris density in Parkinson’s disease by Lei Wan, Andrew Hoover, Giovana Rosa Gameiro, Amanda Virgets, Kylie J. Martinez, Joseph Signorile, Hong Jiang, Jianhua Wang

Get full text

Effects of Alzheimer’s disease plasma marker levels on multilayer centrality in healthy individuals by Alejandra García-Colomo, David López-Sanz, Ignacio Taguas, Martín Carrasco-Gómez, Carlos Spuch, María Comis-Tuche, Fernando Maestú

Get full text