Treatment effects of Xuebijing injection in patients with sepsis by clinical phenotype: a post hoc analysis of the EXIT-SEP trialResearch in context by Xiran Lou, Hui Chen, Nan Shi, Ruixuan Yu, Songli Li, Yi Yang, Songqiao Liu, Jianfeng Xie, Haibo Qiu

“…Phenotype β was associated with older age, chronic illness, and renal dysfunction. Phenotype γ was characterized by respiratory dysfunction. …”
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Alcohol consumption and cognitive aging: can it be beneficial? by Margarita Velikova, Bistra Galunska, Raya Dimitrova, Zlatislav Stoyanov

“…We present a literature review which summarizes the data supporting one of the alternative perspectives on the effect of alcohol consumption on cognitive aging – the possible positive effect of low to moderate drinking. …”
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Auditory agnosia for environmental sounds in Alzheimer’s disease: Effects on daily life by J.A. Coebergh, S. McDowell, T.C.A.M. van Woerkom, J.P. Koopman, J.L. Mulder, F.R.E. Smink, J.D. Blom, S.F.T.M. de Bruijn

“…The effects of this type of agnosia on daily life in Alzheimer’s disease are unknown. …”
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The effect of propofol on the grading of diastolic function: a prospective observational study by Shalin Desai, Zachary Hamilton, Lynh McCloskey, Orode Badakhsh, David Li, Neal W. Fleming

“…Abstract Background Left ventricular diastolic dysfunction accounts for approximately half the cases of heart failure in the community. …”
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Cancer pain – all change please? by Olav Erich Yri, Barry J A Laird

“…Long-term opioid use is also associated with risks including cognitive impairment, opioid-induced hyperalgesia and endocrine dysfunction. This review examines the ongoing relevance and limitations of the WHO ladder, highlights the challenges of opioid toxicity, and advocates for a personalised, multidisciplinary strategy to deliver safe, effective and compassionate cancer pain relief.…”
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Effect of NT-proBNP on Serum Calcium: A Longitudinal Analysis by Maria Rita Stancanelli, Giuseppe Restivo, Thea Corriere, Carmela Cannarozzo, Maria Gabriella Ferrara, Rosario Salemi, Maria Eva Sberna, Angelo Iraci, Ada Restivo, Valeria Furia, Elisa Longhitano, Domenico Santoro, Vincenzo Calabrese

“…This study’s findings indicate that NT-proBNP may influence calcium excretion, possibly through mechanisms involving the sodium–calcium exchanger (NCX) in renal tubules, similar to its effects on sodium homeostasis. <i>Conclusions</i>: This is the first study to evaluate the longitudinal impact of NT-proBNP on serum calcium, highlighting a potential clinical relevance in patients with cardiac dysfunction. …”
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Assessing radonotherapy effectiveness and modulated steroidogenesis in experimental chronic endometritis model by A. E. Chernova, O. V. Remneva, I. P. Bobrov, A. V. Lepilov, O. N. Mazko, O. G. Makarova, N. M. Semenikhina, O. V. Rozhkova, I. V. Grebtsov, D. A. Baranov, S. A. Antonova, V. V. Baranova

“…Radon therapy combined with peloid therapy has a potentiated effect. The use of radon balneotherapy is accompanied by significantly increased progesterone and decreased estradiol level suggesting to conduct clinical trials for confirming its effectiveness in patients with reproductive dysfunction including diseases accompanied by hyperestrogenism.…”
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ASSESSMENT OF DIASTOLIC FUNCTION OF THE LEFT VENTRICLE, INTIMA-MEDIA THICKNESS AND EXERCISE TOLERANCE IN CHD PATIENTS TAKING BISOPROLOL AND IVABRADINE by G. I. Khairutdinova, G. V. Babushkina

“…In the group of patients who received ivabradine, there was improvement of the values of diastolic function of the left ventricle that helped to increase effective duration of diastolic filling of the left ventricle.…”
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Cannabinol (CBN) alleviates age-related cognitive decline by improving synaptic and mitochondrial health by Nawab John Dar, Antonio Currais, Taketo Taguchi, Nick Andrews, Pamela Maher

“…To address this gap, this study investigated the effects of CBN on age-associated cognitive decline and metabolic dysfunction using the SAMP8 mouse model of accelerated aging. …”
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ECT-induced primary open-angle glaucoma in a patient with unstable thyroid function: a case report by Cuiyuan Fu, Cuiyuan Fu, Xiuzhen Yang, Kun Li, Kun Li

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Analysis of the neuronal damage severity and cognitive status in patients after operations on the aortic arch by B. N. Kozlov, D. S. Panfilov, M. O. Berezovskaya, I. V. Ponomarenko, N. I. Afanasyeva, A. I. Maksimov, Yu. K. Podoksenov, M. L. Dyakova, A. M. Gusakova, V. M. Shipulin

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Adverse Ocular Impact and Emerging Therapeutic Potential of Cannabis and Cannabinoids: A Narrative Review by Bondok M, Nguyen AXL, Lando L, Wu AY

“…The current literature reports several adverse ocular effects of cannabis and cannabinoids, including eyelid tremor, ptosis, reduced corneal endothelial cell density, dry eyes, red eyes, and neuro-retinal dysfunction. …”
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OPTIMISATION OF ARTERIAL HYPERTENSION PHARMACOTHERAPY IN PATIENTS WITH METABOLIC SYNDROME: POTENTIAL OF ZOFENOPRIL by T. E. Morozova, T. B. Andrushchishina, S. D. Oshorova

“…This open study of pleiotropic and antihypertensive effects of zofenopril included 32 patients with Stage I-II AH and MS (18 men, 14 women; mean age 54 years (from 48 to 60,5 years)). …”
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Clinical Effectiveness, Clinical Stability, and Effects on Serum Galectin-7 Levels of Dupilumab and JAK Inhibitors in Moderate-to-Severe Atopic Dermatitis: A Real-World, Single-Cen... by Akihiro Horie, Tomomitsu Miyagaki, Chikako Hiranuma, Mami Iijima, Yoshiaki Hara, Shinya Oba, Mina Hashimoto, Reina Omori, Tatsuro Okano, Takafumi Kadono

“…<i>Conclusions:</i> Both dupilumab and JAK inhibitors showed high effectiveness on skin inflammation and decreased a marker of skin barrier dysfunction within 16 weeks. …”
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The Relationship Between Oxidative Stress and Infertility Due to Antihypertensive Drugs in Rattus Norvegicus by Berna Asir, Yakup Kumtepe

“…This study aimed to investigate the effect of antihypertensive drugs on reproductive function in Rattus norvegicus and demonstrate the potential role of oxidative stress in reproductive dysfunction. …”
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Algorithms for the treatment of patients with chronic cerebral ischemia of stages I and II with use of Picamilon: results of an open clinical comparative study by Andrei B. Danilov, Natalia N. Shindryaeva, Irina V. Borodulina, Timothy D. Lunegov

“…Picamilon reduces concentrations of markers of endothelial dysfunction – initially elevated levels of ADMA in both groups and SDMA in group 2. …”
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Ultrasound criteria for assessing the correction of metabolic-associated fatty liver disease and liver blood flow disorders using arginine in patients with coronary artery disease... by S.Ye. Mostovyi, M.M. Zhaivoronok, O.M. Safonova

“…It is known that with COVID-19, the endothelium, the hemostasis system, and the liver are affected with the occurrence of such a complication as metabolic dysfunction-associated steatotic liver disease (MASLD). …”
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Physical, Cognitive, Social, and Functional Health Correlates of Major Depressive Disorder Subtypes: A Systematic Review by Jen E. McKeough, Christopher F. Sharpley, Kirstan A. Vessey, Vicki Bitsika, Rebecca J. Williams, G. Lorenzo Odierna, Ian D. Evans

“…While it has broad health effects, relatively little is known about how these vary across MDD ‘subtypes’, which reflect distinct symptom profiles. …”
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Differentiated disorders of the immune system in acute hematogenic and acute posttraumatic osteomyelitis in children by G. A. Chudilova, V. A. Tarakanov, E. A. Chicherev, Yu. V. Teterin, N. K. Barova, M. N. Mitropanova

“…The condition for spreading of the infectious process into bone is the effect of S. aureus and its impaired elimination due to immune system (IS) dysfunction. …”
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Cirrhotic cardiomyopathy by S. N. Mammayev, A. M. Karimova, T. E. Il’yasova, A. Sh. Khasayev

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