Osteoarthritis-like changes in rat temporomandibular joint induced by unilateral anterior large overjet treatment by Xinru Xie, Rui Chao, Yi Mao, Tianhao Wan, Yexin Wang, Yan Zhu, Weifeng Xu, Xuzhuo Chen, Yong Wang, Zhigui Ma, Shanyong Zhang

“…Disruption of antioxidant systems and mitochondrial dysfunction are involved in cartilage degeneration. …”
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Inhibition of Drp1/Fis1 interaction slows progression of amyotrophic lateral sclerosis by Amit U Joshi, Nay L Saw, Hannes Vogel, Anna D Cunnigham, Mehrdad Shamloo, Daria Mochly‐Rosen

“…Abstract Bioenergetic failure and oxidative stress are common pathological hallmarks of amyotrophic lateral sclerosis (ALS), but whether these could be targeted effectively for novel therapeutic intervention needs to be determined. …”
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Evolution of characteristics of MASLD with and without diabetes: a meta-analysis of placebo arms by Han Ah Lee, Hye Ah Lee, Hwi Young Kim

“…Conclusion Placebo treatment had a greater effect in improving liver steatosis in patients with diabetes compared to those without. …”
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Case report:Acute hepatic and renal failure caused by alcohol and acetaminophen poisoning by Liu Yiyang, He Xinhua

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Preliminary of Cognitive and Systemic Disorders in Rats Due to Chronic Exposure to Aluminum Chloride by Haniyeh Amini, Manizheh Karami

“…Conclusion: Aluminum damages the brain and causes liver dysfunction due to its chronic consumption.…”
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Ten years of Descemet membrane endothelial keratoplasty: Identifying risk factors and early failure signs by Nicole Mechleb, Maria Rizk, Guillaume Debellemanière, Damien Gatinel, Alain Saad

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IGF-1 as a Biomarker for Symptom Severity in Adult Traumatic Brain Injury: Evidence from an Observational Study by Justin Weppner, Kimberly Rosenthal, Jennifer Bath, Tonja Locklear, Melissa Martinez

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Prognostic Scores for Acute Kidney Injury in Critically Ill Patients by Wisble Pereira Sousa, Marcia Cristina da Silva Magro, Alberto Augusto Martins Paiva, Ruth Silva Rodrigues Vasconcelos, Abraão Alves dos Reis, Wellington Luiz de Lima, Tayse Tâmara da Paixão Duarte

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Long COVID in pediatric age: an observational, prospective, longitudinal, multicenter study in Italy by Susanna Esposito, Matteo Puntoni, Michela Deolmi, Greta Ramundo, Giuseppe Maglietta, Marco Poeta, Stefania Zampogna, Claudia Colomba, Agnese Suppiej, Fabio Cardinale, Samantha Bosis, Elio Castagnola, Fabio Midulla, Carlo Giaquinto, Paola Giordano, Giacomo Biasucci, Valentina Fainardi, Francesco Nunziata, Roberto Grandinetti, Anna Condemi, Giuseppe Raiola, Alfredo Guarino, Caterina Caminiti, Long-Covid-Ped Italian Study Group

“…The most frequent symptoms included respiratory issues (43.4%), neurological and cognitive dysfunction (27.7%), gastrointestinal symptoms (22.1%), fatigue (21.6%), and sleep disturbances (18.8%). …”
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High-intensity interval training reduces Tau and beta-amyloid accumulation by improving lactate-dependent mitophagy in rats with type 2 diabetes by Pouria Khosravi, Fereshte Shahidi, Arezoo Eskandari, Kayvan Khoramipour

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Lower Urinary Tract Symptoms in Uterine Myoma: A Systematic Review and Meta-Analysis by Lek-Hong Tan, Li-Hsien Tsai

“…The pooled prevalence for urinary frequency, urgency, nocturia, voiding dysfunction, and overall UI, SUI, UUI, and MUI ranged from 15% to 54%. …”
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BMDM-derived ORP8 suppresses lipotoxicity and inflammation by relieving endoplasmic reticulum stress in mice with MASH by Yi Chen, Kangjie Xie, Caiyang Chen, Xihui Wang, Chenchen Ma, Zhangxiang Huang, Yingfu Jiao, Weifeng Yu

“…Abstract Background and aims Metabolic dysfunction-associated steatohepatitis (MASH) is one of the most common chronic liver diseases worldwide, and specific treatment modalities are lacking. …”
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The association between resting heart rate and HbA1c-assessed glycemic control in patients with type 2 diabetes in Eastern China by Xiangyu Chen, Feng Lu, Jie Zhang, Xiaofu Du, Chunxiao Xu, Mingbin Liang, Lijin Chen, Jieming Zhong

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Validation of Senescence of the Role of ATM/P53 Pathway in Myocardial Senescence in Mice with Sepsis by Yan Z, Shi X, Ding R, Xia F, Du Y, Wang X, Peng Q

“…Targeting DDR pathways, as demonstrated by KU60019 treatment, provides novel insights into the role of cellular senescence in severe sepsis and its potential therapeutic implications for improving cardiovascular prognosis in septic patients.Keywords: sepsis-induced myocardial dysfunction, cell senescence, transcriptome, key genes, database, ATM/P53 pathway…”
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Inhospital changes of left ventricular diastolic function in patients undergoing coronary bypass surgery by A. R. Mingalimova, O. M. Drapkina, N. M. Bikbova, M. A. Sagirov, M. Kh. Mazanov, A. V. Timerbaev, I. A. Argir

“…According to echocardiography, type 1 diastolic dysfunction prevailed in both groups; types 2 and 3 LV diastolic dysfunction were not identified. …”
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Multi-center randomized superiority clinical trial in the early phase of mechanically ventilated patients to preserve diaphragm thickness using non-invasive magnetic phrenic nerve... by Annia F. Schreiber, Carles Subirà, Michael Sklar, Marlene Santos, Matthew Ko, Alessandro Panelli, Stefan J. Schaller, Danny Theodore, Daniel D. Rowley, David Watson, Pramod Bonde, Elias N. Baedorf Kassis, Daniel S. Talmor, Marco Ranieri, Ewan C. Goligher, Arthur Slutsky, Laurent J. Brochard

“…Abstract Background Ventilator-induced diaphragmatic dysfunction (VIDD) occurs in up to 60% of mechanically ventilated patients and prolongs ventilatory dependance. …”
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Altered brain regional homogeneity, depressive symptoms, and cognitive impairments in medication-free female patients with current depressive episodes in bipolar disorder and major... by Sulin Ni, Ting Peng, Shuzhan Gao, Chenxi Ling, Fan Wu, Jing Jiang, Jing Sun, Chaoyong Xiao, Xijia Xu

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Perfluorohexyloctane ophthalmic solution for dry eye disease: pooled analysis of two phase 3 clinical trials by Ahmad M. Fahmy, Jennifer S. Harthan, David G. Evans, Jack V. Greiner, Joseph Tauber, John D. Sheppard, Sonja Krösser, Jason L. Vittitow

“…BackgroundDry eye disease (DED) is commonly caused by excessive tear film evaporation due to Meibomian gland dysfunction (MGD). There is a need for DED treatment options that address tear evaporation and benefit patients across a broad range of demographic and disease characteristics. …”
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Dietary oxidized lipids in redox biology: Oxidized olive oil disrupts lipid metabolism and induces intestinal and hepatic inflammation in C57BL/6J mice by Yifan Bao, Magdalena Osowiecka, Christiane Ott, Vasiliki Tziraki, Lukas Meusburger, Claudia Blaßnig, Daniela Krivda, Petra Pjevac, Joana Séneca, Matthias Strauss, Christina Steffen, Verena Heck, Soner Aygün, Kalina Duszka, Kevin Doppelmayer, Tilman Grune, Marc Pignitter

“…However, the redox biological implications and health effects of oxidized olive oil (ox-OO) remain underexplored. …”
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Identification of a 2-phenoxychromone derivative as a novel inhibitor of lipid droplet formation in hepatocytes and adipocytes by Yu-Tsen Hsieh, Tung-Hsuan Kang, Hsin-Yi Hung, Yi-Han Chang, Kuan-Chen Cheng, Chia-Yih Wang, Wen-Tai Chiu, Pai-Sheng Chen, Shih-Chieh Lin, I-Chen Peng

“…Dysregulated lipid droplet (LD) accumulation in hepatocytes increases the risk of metabolic dysfunction-associated steatotic liver disease (MASLD), formerly known as non-alcoholic fatty liver disease (NAFLD), the most common chronic liver disease worldwide. …”
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