C-C chemokine ligand 5 from women subcutaneous adipose tissue has a central role in vascular aging by Laura Le Pelletier, Kenza Ngono Ayissi, Jennifer Gorwood, Emilie Capel, Romain Morichon, Matthieu Mantecon, Martine Auclair, Rohia Alili, Christine Katlama, Lise Cuzin, Michael Atlan, Carine Beaupère, Christine Poitou, Franck Boccara, Bruno Fève, Jacqueline Capeau, Claire Lagathu, Véronique Béréziat

“…Thus, CCL5/RANTES secreted from SCAT during aging could contribute to endothelial dysfunction by exerting both local and systemic effects. …”
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IMPACT OF INTRA-OPERATIVE SEDATION WITH SPINAL ANESTHESIA DURING UTERUS AMPUTATION ON COGNITIVE FUNCTIONS IN THE POST-OPERATIVE PERIOD by T. I. Akimenko, V. M. Zhenilo, E. A. Lebedeva, S. V. Zdiruk, Yu. S. Aleksandrovich

“…The post-operative cognitive dysfunction is an adverse disorder of higher functions of the nervous system, which develops in the post-operative period and it is associated with surgery and anesthesia. …”
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The impact of Parkinson’s Disease on interlimb coordination: a scoping review of gait adaptability by Morteza Farivar, Boglarka S. Huddleston, Adam C. King, Adam C. King

“…The findings emphasize the variability in PD’s motor effects and highlight the need for individualized assessments and targeted strategies to address gait dysfunction and coordination impairments.DiscussionThis review highlights the critical impact of PD on gait dynamics and interlimb coordination, reinforcing the need for personalized interventions aimed at improving coordination, enhancing mobility, reducing fall risk, and improving quality of life.…”
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The influence of obesity on IOS parameters in asthma, COPD, and other lung diseases: analyzed by random forest by Thomas Ringbaek, Lars Froelund, Jann Mortensen, Henrik H. El Ali

“…With rising obesity rates, understanding its effects on respiratory health is increasingly essential. …”
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Perioperative fluid therapy impairs lymphatic pump function in male rats by Rebecca C. Harlow‐Adamek, Reetu Singh, Randolph H. Stewart, Cristine L. Heaps, Glen A. Laine, Charles S. Cox Jr., Ranjeet M. Dongaonkar

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A systematic review of Alzheimer's disease: exploring genetic and environmental risk factors, biomarkers, and future pharmacotherapy for cognitive decline and neurodegeneration by Debraj Dey, Deepannita Roy Mukherjee, Abu Shoeb, Pinki Biswas, Saikat Santra

“…Aging is the primary risk factor, but metabolic, genetic, and environmental influences, including inflammation and vascular dysfunction, significantly contribute to disease onset and progression. …”
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Delivery Mode and the Pelvic Floor Function of Primiparous Women at Early Postpartum: An Observational Retrospective Cohort Study by Xiaolei Chi, Lin Wen, Lan Chen, Hongxia Zhu

“…Background: Different modes of delivery are strongly associated with postpartum pelvic floor muscle (PFM) injury and postpartum pelvic floor dysfunction. This study used Glazer PFM surface electromyography (sEMG) to objectively assess postpartum PFM function to determine the effects of different modes of delivery on pelvic floor function in the early postpartum period in primiparous women. …”
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Comparison Between End-to-end Anastomosis and Buccal Mucosa Graft in Short Segment Bulbar Urethral Stricture: a Meta-analysis Study by Prahara Yuri, Irfan Wahyudi, Arry Rodjani

“…Results:We analyze 10 studies in this meta-analysis. Sexual dysfunction following EE and BMG were found in 24.6% (45/183) patients and 9.1% (11/122) patients, respectively (overall RR 2.54; 95% CI: 1,44-4,47; p=0.001). …”
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A machine learning prediction model for Cardiac Amyloidosis using routine blood tests in patients with left ventricular hypertrophy by Yuling Pan, Qingkun Fan, Yu Liang, Yunfan Liu, Haihang You, Chunzi Liang

“…Furthermore, XGBoost identified unique biomarker signatures indicative of multisystem dysfunction in CA patients, with significant changes in eGFR, FT3, cTnI, ANC, and NT-proBNP. …”
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Sex differences in inflammation and markers of gut integrity in long COVID by Jared C. Durieux, Ziad Koberssy, Joviane Daher, Jhony Baissary, Marc Abboud, Ornina Atieh, Christopher Woolverton, Grace A. McComsey

“…Abstract Endothelial damage represents an essential pathogenic mechanism of respiratory and multiorgan dysfunction as seen in the post-acute phase of COVID-19. …”
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Calorie and time-restricted feeding improves liver and kidney histopathology in streptozotocin-induced type 1 diabetic rats by Indra Putra Taufani, Sri Rahmatul Laila, Sri Tasminatun, Sailent Rizki Sari Simaremare, Meity Mardiana, Jiro Hasegawa Situmorang

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Comparison Between End-to-end Anastomosis and Buccal Mucosa Graft in Short Segment Bulbar Urethral Stricture: a Meta-analysis Study by Prahara Yuri, Irfan Wahyudi, Arry Rodjani

“…Results:We analyze 10 studies in this meta-analysis. Sexual dysfunction following EE and BMG were found in 24.6% (45/183) patients and 9.1% (11/122) patients, respectively (overall RR 2.54; 95% CI: 1,44-4,47; p=0.001). …”
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Ketogenic therapy for schizophrenia: evidence, mechanisms, and clinical perspectives by Cristiano Chaves, Cristiano Chaves, Jennifer Fabe, Fabiano A. Gomes, Heather McNeely, Massimo Tusconi, Mauro Giovanni Carta, Serdar M. Dursun, Serdar M. Dursun, Jaime E. C. Hallak, Jaime E. C. Hallak, Jaime E. C. Hallak, Elisa Brietzke

“…Mechanistically, ketone bodies enhance mitochondrial function, modulate neurotransmitter systems (GABA, glutamate, dopamine), and reduce inflammation and oxidative stress. These effects may address core dysfunctions in schizophrenia that are unresponsive to dopamine-targeting pharmacotherapies.DiscussionKetogenic therapy holds potential for addressing unmet clinical needs in schizophrenia, including negative and cognitive symptoms, treatment-resistant cases, and antipsychotic-induced metabolic syndrome. …”
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Prediction of preterm birth in women with fetal growth restriction – Is the weekly change in sFlt‐1/PlGF ratio or PlGF levels useful? by Jesrine Hong, Kylie Crawford, Erika Cavanagh, Vicki Clifton, Sailesh Kumar

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Sonographic diaphragmatic parameters as a predictor of weaning failure in critically ill patients in need of invasive mechanical ventilation: a prospective observational cohort stu... by Prathmesh G. Kumbhar, Manvinder Tejpal, Sunaina T. Karna, Pooja Singh, Saurabh Saigal, Vaishali Waindeskar

“…In conclusion, pre-intubation sonographic DE of less than 10.5 mm can effectively predict complicated weaning and may be an adjunct in prognostication. …”
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Asymmetric Dimethylarginine as a Potential Mediator in the Association between Periodontitis and Cardiovascular Disease: A Systematic Review of Current Evidence by Biagio Rapone, Francesco Inchingolo, Giulia Margherita Tartaglia, Maurizio De Francesco, Elisabetta Ferrara

“…Asymmetric dimethylarginine (ADMA), an endogenous inhibitor of nitric oxide synthase, has emerged as a potential biomarker linking periodontitis, endothelial dysfunction, and CVD. This systematic review aimed to synthesize the existing evidence on the relationship between ADMA, periodontitis, and CVD, and to evaluate ADMA’s potential as a biomarker for periodontal disease progression and its correlation with endothelial dysfunction. …”
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Cardiac Transplantation Does Not Improve Exercise Tolerance, Muscle Mass, or Substrate Metabolism in Barth Syndrome by W. Todd Cade, Kathryn L. Bohnert, Linda R. Peterson, Lisa de las Fuentes, Emily Poehlein, Cynthia L. Green, Christina A. Pacak, Barry J. Byrne, Dominic N. Reeds, Adil Bashir, Brian Feingold, Carolyn Taylor

“…While cardiac transplantation can improve heart function in BTHS patients, the metabolic effects of this procedure remain poorly understood. …”
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HDAC9-Mediated Pyroptosis Promotes Orthodontically Induced Inflammatory Root Resorption by Lin Chen, Limin Liu, Tianwei Lin, Zhihui Mai, Hongfei Lu, Bingxue Hu, Junhao Huang, Hong Ai

“…HDAC9 overexpression in hPDLFs induced pyroptosis and promoted osteoclast differentiation. These effects were reversed by pyroptosis inhibitor. CUT&Tag analysis showed that HDAC9 overexpression resulted in an enrichment of deacetylated genes on mitochondrial dysfunction-associated pathways. …”
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miR-155 induces sepsis-associated damage to the intestinal mucosal barrier via sirtuin 1/nuclear factor-κB-mediated intestinal pyroptosis by Li Zhihua, Wang Yi, Huang Weiwei, Shi Xingyu, Ma Tao, Yu Xiangyou

“…Several studies have confirmed the role of miR-155 in sepsis and other diseases. However, the effect of miR-155 on intestinal pyroptosis in the context of intestinal mucosal barrier dysfunction during sepsis remains unclear. …”
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Saccharomyces boulardii (CNCM I-745) improves intestinal damage in sepsis by remodeling intestinal flora structure by Hui-Ying Liu, Yao Li, Yi-Lu Lin, Yu-Jia Tang, Jin-Da Zhao, Jia Xu, Kuo Wang, Ying-Fei Zhi, Yan Zhang, Jia-Le Deng, Kai Kang, Ying Chen, Yang Gao

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