Role of lipopolysaccharide in genesis of microvascular complications in type 1 diabetes mellitus by V. A. Beloglazov, I. A. Yatskov, D. I. Ulyanova

“…Chronic excessive intake of LPS into the systemic bloodstream can lead to the development of persistent low-grade inflammation accompanied by changes in architectonics of extracellular matrix, potentiate the development of endothelial dysfunction and vascular inflammation. The studies of LPS effects upon clinical course of DM1 are promising and require further in-depth research.…”
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Studying the possibilities of pharmacological correction of hypoxia-induced pulmonary hypertension using a phenolic compound with a laboratory cypher KUD975 by L. V. Korokina

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Social jetlag elicits fatty liver via perturbed circulating prolactin rhythm-mediated circadian remodeling of hepatic lipid metabolism by Peng-Zi Zhang, Ying-Huan Shi, Yu-Xin Guo, Ya-Yuan Li, Hong-Li Yin, Tian-Yu Wu, Ye Zhu, Jia-Xuan Jiang, Yan Bi

“…Restoration of PRL rhythm could effectively alleviate SJL-induced fatty liver, providing new insight into treating MASLD.…”
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Association of Tricuspid Regurgitation With Mortality in Heart Failure With Left-Sided Heart Disease by Mitsunobu Kitamura, MD, Kazuaki Amami, MD, Tomoyuki Yaguchi, MD, Kouya Okabe, MD, Yasuyuki Shiraishi, MD, Ryo Nakamaru, MD, Yuji Nagatomo, MD, Ayumi Goda, MD, Michiru Nomoto, MD, Atsushi Mizuno, MD, Munehisa Sakamoto, MD, Yumiko K. Ichihara, MD, Takashi Kohno, MD, Shun Kohsaka, MD, Tsutomu Yoshikawa, MD

“…Using a multivariable Cox hazard model, the survival effect of TR on mortality in patients with LVD was examined. …”
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Association between the triglyceride-glucose index and liver fibrosis in adults with metabolism-related fatty liver disease in the United States: a cross-sectional study of NHANES... by Yuou Ying, Yuan Ji, Ruyi Ju, Jinhan Chen, Mingxian Chen

“…A restricted cubic spline (RCS) model was used to explore nonlinear effects, and receiver operating characteristic (ROC) curves were applied to evaluate the effectiveness in predicting. …”
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Visceral adipose tissue mediates the relationship between left ventricular global longitudinal strain and insulin resistance among adults living with type 2 diabetes by Pavel Martinez-Dominguez, Paola Gomez-Aviles, Kenya Bautista-García, Neftali Eduardo Antonio-Villa, Enrique C. Guerra, Paloma Almeda-Valdes, Alexandro J. Martagón, Alejandro Campos Munoz, Maria Jose Santa-Ana-Bayona, Erick Alexanderson, Carlos A. Aguilar Salinas, Nilda Espinola-Zavaleta

“…However, the relationship between VAT, cardiac dysfunction and the meditation capacity of VAT related to IR has not been fully characterized. …”
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Impact of maintenance hemodialysis on cognitive function of patients by LIN Yan, HE Hua

“…Objective To investigate the impact of maintenance hemodialysis(MHD) on cognitive function of patients with chronic renal failure(CRF).Methods Sixty-five cases of CRF undergoing MHD were recruited between January 2014 to August 2015 from Department of Nephrology,the People’s Hospital of Boertala Zhou.The effect of MDH on cognitive function in patients with CRF was observed.The cognitive function was assessed by the Montreal Cognitive Scale(MoCA) before and after treatment Sixty-five patients were divided into normal cognition(NC) group(n = 22),and cognitive impairment(CD group(n = 43) according to the MoCA scores.Results The average scores of MoCA in MHD patients were(21.8 ± 4.4),which were significantly lower than those in the control group.After MHD,the MoCA scores in NC group(23.2 ± 1.7) and CI group(18.7 ± 3.6) were significantly lower than those before MHD[(26.5 ± 1.2) and(21.3 ± 2.9) respectively].There was significant difference between the two groups(P<0.05).The multivariate analysis revealed that low education level,older age,low hemoglobin levels and a long duration of dialysis were factors influencing cognitive dysfunction of MHD patients with the differences being statistically significant(P<0.05).Conclusions MHD can influence cognitive function in patients with CRF,and education level,age,hemoglobin levels and duration of dialysis may be the risk factors.…”
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Acute long-acting anticoagulant rodenticide poisoning in pregnancy: a case report by Yanxi Jia, Yanxi Jia, Yongchi Zhan, Yongchi Zhan, Guiqiong Huang, Guiqiong Huang, Chunyan Deng, Chunyan Deng, Haiyan Yu, Haiyan Yu

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Compliance and Adherence to Pelvic Floor Exercise Therapy in People with Pelvic Floor Disorders: A Systematic Review and Meta-Analysis by Inmaculada Villa-Del-Pino, José-Jesús Jiménez-Rejano, Manuel Rebollo-Salas, Álvaro-José Rodríguez-Domínguez, Carmen-María Suárez-Serrano

“…Background: The impact of muscle-training treatment on quality of life and functional outcomes in people with pelvic floor dysfunction may be related to adherence rates. Methods: Nine electronic databases were searched for studies published up to 15 October 2024. …”
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Advances and Challenges in Pediatric Sepsis Diagnosis: Integrating Early Warning Scores and Biomarkers for Improved Prognosis by Susanna Esposito, Benedetta Mucci, Eleonora Alfieri, Angela Tinella, Nicola Principi

“…Although various early warning scores exist, their effectiveness is limited, particularly in prehospital settings where accurate, rapid assessment is crucial. …”
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Physiotherapy management of Parkinson’s disease in a tertiary hospital in Nigeria: a case report by Moses Ayomide Olayemi, Rukayat Ajoke Bello, Olawale Isreal Oshomoji, John Oluwadunsin Adeolu

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Dysregulated lipid metabolism in kidney stone pathogenesis: a literature review of mechanistic insights and therapeutic implications by Quan Wen, Qiuyu Li, Haoji Zhou, Boyan Su, Yalin Ren, Qiqi He

“…Additionally, small-molecule modulators targeting the PPAR/FABP pathway and novel delivery systems, such as mitochondrion-targeted liposomes, have demonstrated the potential to intervene in the lipid metabolism/organelle damage axis, although clinical translation faces challenges such as species differences (The paradoxical effects of PPARα agonists in rodents versus humans) and safety concerns. …”
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Adenosine stress myocardial perfusion imaging and myocardial work in evaluating INOCA by Xuemei Zhang, Shuixiu Dou, Feifei Zhang, Ping Lou, Jing Jin, Ying Zhao, Xin Zhao, Fengsheng Li, Yuhan Li

“…Under both resting and stress conditions, the β values of patients in the INOCA group were significantly different from those in the control group, and the CFR in the INOCA group was significantly different from that in the control group (P < 0.05, Table 2). AS-MCE effectively identifies microcirculatory dysfunction in INOCA, demonstrating superior diagnostic utility over MW for non-obstructive ischemia.…”
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Cross‐Sectional Association Between Left Ventricular Geometric Patterns, Cortical Cerebral Microinfarcts, and Cognition by Jiannan Huang, Caroline Robert, Lieng‐Hsi Ling, Christopher Chen, Saima Hilal

“…As a novel magnetic resonance imaging marker of cerebral small vessel disease and a risk factor for cognitive dysfunction, cortical cerebral microinfarcts (CMIs) have been associated with heart disease through mechanisms including cardioembolism and cerebral hypoperfusion. …”
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Association Between Oral Microbiota Dysbiosis and the Risk of Dementia: A Systematic Review by Alain Manuel Chaple-Gil, Meylin Santiesteban-Velázquez, Joaquín Juan Urbizo Vélez

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‘Feeling Hot’: Exploring the feasibility of nocturnal erection detection through penile temperature measurements by Hille J. Torenvlied, Evelien Trip, Wouter Olthuis, Loes I. Segerink, Rob C. M. Pelger, Jack J. H. Beck

“…Challenges arose in accurately determining erection duration and subsequent erection onsets due to the persistence of elevated temperatures following initial erections, termed the ‘Staying Hot effect’. Reference thigh temperature measurements aided in addressing this challenge. …”
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Latest trends on interplay of autophagy, adipose tissue, and gut microbiota in obesity-related metabolic disorders by Claudette Butoyi, Muhammad Asad Iqbal, Isaac Duah Boateng

“…Purpose of review: This review aims to synthesize current research on the intricate relationships among visceral obesity (VO), autophagy (Atg), gut microbiota, and adipose tissue dysfunction, all of which contribute significantly to insulin resistance (IR) and associated metabolic disorders. …”
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Ocular Manifestations in Children with Vernal Keratoconjunctivitis by Matteo Capobianco, Marco Zeppieri, Giuseppe Gagliano, Federico Visalli, Fabiana D’Esposito, Roberta Foti, Ludovica Cannizzaro, Daniele Tognetto, Caterina Gagliano

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Evaluation of left ventricular functions with two-dimensional speckle-tracking echocardiography (2D-STE) and N-terminal ProBNP in diabetic children by Ayşe Şimşek, Özlem Turan, Murat Çiftel, Fırat Kardelen, Erdem Durmaz, Sebahat Özdem, Gayaz Akçurin, Halil Ertuğ

“… The purpose of this study was to examine the existence of subclinical left ventricular dysfunction by using 2D-STE and NT-ProBNP levels in children and adolescent patients with type 1 diabetes mellitus. …”
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Erectile function rehabilitation with phosphodiesterase type 5 inhibitors in patients following nerve-sparing radical prostatectomy: a comparative efficacy analysis of different co... by E. V. Pomeshkin, M. V. Shamin, B. A. Nejmark

“…Despite the selective patient screening and improvements in surgical techniques for radical prostatectomy (RP), the incidence of erectile dysfunction (ED) remains relatively high. The efficacy of phosphodiesterase type 5 inhibitors (PDE5i) in patients undergoing nerve-sparing RP can vary from 35% to 75%. …”
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