Tau oligomers impair memory and synaptic plasticity through the cellular prion protein by Claudia Balducci, Franca Orsini, Milica Cerovic, Marten Beeg, Beatrice Rocutto, Letizia Dacomo, Antonio Masone, Eleonora Busani, Ilaria Raimondi, Giada Lavigna, Po-Tao Chen, Susanna Leva, Laura Colombo, Chiara Zucchelli, Giovanna Musco, Nicholas M. Kanaan, Marco Gobbi, Roberto Chiesa, Luana Fioriti, Gianluigi Forloni

“…Abstract Deposition of abnormally phosphorylated tau aggregates is a central event leading to neuronal dysfunction and death in Alzheimer’s disease (AD) and other tauopathies. …”
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Changes in local mineral homeostasis facilitate the formation of benign and malignant testicular microcalcifications by Ida Marie Boisen, Nadia Krarup Knudsen, John E Nielsen, Ireen Kooij, Mathilde Louise Bagger, Jovanna Kaludjerovic, Peter O'Shaughnessy, Peter W Andrews, Noriko Ide, Birgitte G Toft, Anders Juul, Arnela Mehmedbasic, Anne Jørgensen, Lee B Smith, Richard Norman, Ewa Rajpert-De Meyts, Beate Lanske, Martin Blomberg Jensen

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Structural and functional changes of the heart and electrical disorders in patients with coronary artery disease with concomitant anemia by M. O. Konovalova, N. S. Mikhailovskaya

“…The aim of the study: to investigate the effect of concomitant anemia on the features of cardiac remodeling and electrical disorders in patients with coronary artery disease (CAD). …”
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Expert Consensus on Clinical Application of Lower Limb Rehabilitation Robots by ZHANG Lixin, BAI Dingqun, BAI Yulong, CHEN Wenhua, CHEN Yan, DU Qing, FAN Maohua, HE Hongchen, HUANG Liping, JIA Jie, LI Jianhua, LI Lei, PAN Yu, SU Min, WANG Hongtu, YIN Yong, ZHANG Bi

“…However, determining whether its training effect is superior to conventional rehabilitation therapy requires further clinical study (high-level evidence). …”
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CPT1A mediated preservation of mitochondrial inhibits pyroptosis in pancreatic acinar cells by Yijiang Liu, Yangbo Liu, Xiuxian Yu, Simin Tian, Xiaojuan Li, Yu Gao, Xin Bao, Xiaoyi Wu, Boli Zhang, Wen Huang

“…IntroductionCarnitine palmitoyltransferase 1A (CPT1A) is crucial for mitochondrial function, and its dysfunction has been linked to the development of several diseases. …”
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Impact of spinal cord anomalies on defecation and quality of life in children with anorectal malformations by FAN Linxiao, FENG Wei, XIANG Chenzhu

“…Multiple linear regression analysis indicated that both SCA and sacral bone anomalies exerted notably negative impacts on the Rintala score and PedsQL 4.0 score (P≤0.001), with SCA having the most pronounced effect. Conclusion‍　‍SCA is closely associated with postoperative defecation dysfunction and diminished quality of life in ARM children. …”
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Dry eye treatment optimization in patients prior to refractive surgery by S. N. Sakhnov, S. V. Yanchenko, A. V. Malyshev, Z. M. Blyagoz, G. A. Klimenova

“…Purpose. To evaluate the effectiveness of dry eye syndrome (DES) treatment in patients with meibomian gland dysfunction (MGD) before refractive surgery.Materials and methods. …”
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Shenfu injection promotes self-renewal of intestinal stem cells in sepsis-induced intestinal injury via inducing ATF4 expression by Yunxin Deng, Lingyun Lu, Jinrong Li, Liya Gao, Yihui Wang, Nataša Petrović, Fengyong Yang, You Li, Mei Meng

“…IntroductionShenfu injection (SFI) is widely used in clinical severe conditions including sepsis due to its pharmacological effects of invigorating Qi and reviving Yang for resuscitation. …”
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Naphthenic Acid Fraction Components-Induced Metabolic and Mitochondrial Alterations in Rat Hepatoma Cells: Monitoring Metabolic Reprogramming with Tryptophan–Kynurenine Ratio by Laiba Jamshed, Amica Marie-Lucas, Genevieve A. Perono, Gregg T. Tomy, Jim J. Petrik, Richard A. Frank, L. Mark Hewitt, Philippe J. Thomas, Alison C. Holloway

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Outcomes of lung transplantation for end stage lung disease with connective tissue disease: a systematic review and meta-analysis by Jihong Liu, Rui Zhou, Zhan Li, Yabin Li, Huizhen Li, Miao Liu, Fei Xie

“…A randomized or fixed-effect model was applied according to the heterogeneity test. …”
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The impact of disease activity and interferon-α on the nervous system in systemic lupus erythematosus by Kristoffer A. Zervides, Elsa Grenmyr, Shorena Janelidze, Petrus Linge, Jessika Nystedt, Petra C. Nilsson, Pia C. Sundgren, Oskar Hansson, Anders A. Bengtsson, Andreas Jönsen

“…Multivariate linear mixed-effect, linear regression, and logistic regression models were used for the statistical analyses. …”
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The role of mitochondria in the ischemic-reperfusion damage of the brain in operations on aortal arch in conditions of experiment by S. M. Gramatiuk, Yu. V. Ivanova, V. I. Kravchenko, O. O. Lohvinenko

“…Due to simultaneous action of these processes the mitochondrial functioning fails so significantly, that becomes one of the key moments in cerebral cellular dysfunction and death. Statistically meaningful difference, taking into account the results, between two groups of investigated animals was not revealed. …”
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Lycium ruthenicum Murr. treatment attenuates APPswE/PS1ΔE9 mouse model-like mitochondrial dysfunction in Slc25a46 knockout mouse model by Min Wang, Tianxiong Xu, Li Gao, Chujun Huang, Piao Xu, Congcong Gong, William Kwame Amakye, Linfeng Liao, Maojin Yao, Jiaoyan Ren

“…Mitochondrial dysfunction is proposed to be substantially associated with ageing and ageing-related diseases like Alzheimer’s disease (AD). …”
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A comparative genomic study across 396 liver biopsies provides deep insight into FGF21 mode of action as a therapeutic agent in metabolic dysfunction‐associated steatotic liver dis... by Shifang Tang, Jürgen Borlak

“…Eventually, we explored 188 validated FGF21 targets, and for ≥10 patients showing the same changes, we constructed MASLD‐associated networks to determine the effects of FGF21 in reverting metabolic dysfunction. …”
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Jiedutongluotiaogan Formula Improves Pancreatic Dysfunction in db/db Mice through Modulating the Gut Microbiota-Short Chain Fatty Acids-NLR Family, Pyrin Domain–Containing Protein... by Jin-Li Luo, Wen-Qi Jin, Li Wang, Qi Zhang, Yu Wang, Cui Wu, Yue Qu, Yu-Ting Peng, Li-Wei Sun, Chun-Li Piao

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Mono-(2-ethylhexyl) phthalate induces trophoblast hypoxia and mitochondrial dysfunction through HIF-1α-miR-210-3p axis in HTR-8/SVneo cell line by Sunitha Meruvu, Zehuan Ding, Mahua Choudhury

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Human Placental Mesenchymal Stem Cells-Exosomes Alleviate Endothelial Barrier Dysfunction via Cytoskeletal Remodeling through hsa-miR-148a-3p/ROCK1 Pathway by Yuzhen Lv, Wenqin Yu, Ruiui Xuan, Yulu Yang, Xiaolan Xue, Xiaowei Ma

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Association of serum uric acid-to-high-density lipoprotein cholesterol ratio with cardiovascular disease risk in patients with metabolic dysfunction-associated fatty liver disease:... by Xianyao Wang, Yuchen Shi, Ying Zi, Jun Long, Rongjie Shi

“…ObjectiveThe relationship between the serum uric acid-to-high-density lipoprotein cholesterol ratio (UHR) and cardiovascular disease (CVD) risk in patients with metabolic dysfunction-associated fatty liver disease (MAFLD) is unknown. …”
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Meta-analysis of motor imagery therapy on swallowing dysfunction in stroke patients (运动想象疗法对脑卒中后患者吞咽功能障碍影响的Meta分析) by GUO Jiaxin (郭嘉欣), GU Yufang (谷雨芳), LIU Kaiyue (刘凯月), MENG Xuefeng (孟雪峰), SUN Yingtong (孙颖童), WEI Jinrong (魏金荣)

“…Objective To systematically evaluate the effect of motor imagery therapy (MI) on swallowing dysfunction in post-stroke patients. …”
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Comparative evaluation of the impact of candesartan and ramipril therapy on the levels of GDF 15 and NTproBNP, structural and functional performance of the heart in patients with c... by V. D. Syvolap, Ya. V. Zemlyaniy

“…Aims. Diastolic dysfunction of the left ventricle in patients with coronary artery disease affects the prognosis and is associated with the frequency of hospitalization for fi rst arisen heart failure. …”
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