Separation of 1,3-Dimethylamylamine (1,3-DMAA) Stereoisomers, a Stimulant Drug, by Liquid Chromatography by Maria de Almeida Mexia de Almeida, Virgínia M. Gonçalves, Alexandra S. Maia, Diana Dias da Silva, Ricardo Jorge Dinis-Oliveira, Cláudia Ribeiro

“…Objective: To develop a semipreparative liquid chromatography with diode array detection (LC-DAD) method for separating the stereoisomers of 1,3-DMAA. …”
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Research and application of micro-scale fracture prediction technology for deep coalbed methane based on five-dimensional seismic data by Lei ZHANG, Fengyin XU, Jiangnan TONG, Feng ZHANG, Feng WANG, Wei HOU, Yihang CHANG, Songyi HOU, Xiangbing PEI, Zhenyi CAO, Tong CHEN, Xuefeng LI, Ke ZHOU, Yongzhou LI, Huaibin ZHEN, Wenting ZENG

“…By integrating regional tectonic stress fields from different periods, field outcrops, imaging logging, and array sonic logging data, we verified the reliability of our research findings on the degree and direction of fracture development. …”
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JAG1 MUTATION SPECTRUM IN CASES WITH ALAGILLE SYNDROME FROM TURKIYE by Ayça Dilruba Aslanger, Behiye Tuğçe Yıldırım, Tuğba Kalaycı, Leyli Şentürk, Şahin Avcı, Umut Altunoğlu, Çağrı Güleç, Volkan Karaman, Güzide Doğan, Zerrin Önal, Özlem Durmaz, Birsen Karaman, Zehra Oya Uyguner

“…Karyotype, fluorescence in situ hybridization (FISH), array comparative genomic hybridization (aCGH), and JAG1 gene sequencing utilizing next-generation and Sanger sequencing methodologies were conducted.Result: The presence of both large deletion and small variants associated with Alagille syndrome was detected in all cases. …”
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Troxerutin suppresses the stemness of osteosarcoma via the CD155/SRC/β-catenin signaling axis by Junkai Chen, Hongbo Li, Qinglin Jin, Xiaoguang Li, Yiwen Zhang, Jingnan Shen, Gang Huang, Junqiang Yin, Changye Zou, Xinyu Li, Xin He, Xianbiao Xie, Tiao Lin

“…Utilizing a comprehensive array of experimental methods, including CCK-8 assay, colony formation assay, Transwell assay, and in vivo animal models, we unequivocally demonstrate that CD155 significantly potentiates the malignancy of osteosarcoma both in vitro and in vivo. …”
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Curvas de desempenho de válvulas reguladoras de pressão novas e com diferentes tempos de utilização Performance curves of new and used pressure regulating valves by Sílvio C. R. V. Lima, José A. Frizzone, Raimundo N. T. Costa, Francisco de Souza, Anderson S. Pereira, Carmelo C. Machado, Manoel Valnir Júnior

“…Pressure regulators of a given model were collected from several central pivot systems and from different spans in the system, such that an array of pressure regulators with 2000, 2500, 6000, 8500, 9000 and 10000 h of operation at several water qualities were obtained. …”
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Synergy of exercise and hypoxia for brain health and aging – A narrative review by Johannes Burtscher, Martin Kopp

“…The precise mechanisms how direct exercise effects are transmitted to the brain remain incompletely understood. …”
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Structural characterization, derivatization, and bioactivities of secondary metabolites produced by termite-associated Streptomyces lannensis BYF-106 by Jun Wu, Miao Zhang, Jian Tao, MengRu Liu, JianHao Xiong, TaoShan Jiang, YaXuan Wang, XiaoHong Li, YueYue Li, CaiPing Yin, ShuXiang Zhang, XinHua Liu, YingLao Zhang

“…By contrast, insect-associated Streptomyces have been shown to produce a more diverse array of unique bioactive secondary metabolites compared to soil Streptomyces. …”
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Advancing Heart Valve Replacement: Risk Mitigation of Decellularized Pulmonary Valve Preparation for Its Implementation in Public Tissue Banks by Rodríguez Martínez JI, Castells-Sala C, Piteira AR, Montagner G, Trojan D, Martinez-Legazpi P, Acosta Ocampo A, Fernández-Santos ME, Bermejo J, Jashari R, Pérez ML, Agustí E, Tabera J, Vilarrodona A

“…However, additional in vivo studies and tissue stability tests are still necessary to address the remaining risks associated with reagents’ effect on extracellular matrix and storage conditions, which could influence implant failure, before the clinical evaluation procedures can be implemented to determine the efficacy and safety of the new decellularized heart valves. …”
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Endogenous HLA-DQ8αβ programs superantigens (SEG/SEI) to silence toxicity and unleash a tumoricidal network with long-term melanoma survival by David Bradley, Peter Knopick, David Terman, Nathan Riha, Travis Alvine, Riley Larson, Cedric Badiou, Gerard Lina, John Ballantyne

“…Such toxicity has narrowed their therapeutic index while neutralizing antibodies have nullified their therapeutic effects.Methods Female HLA-DQ8 (DQA*0301/DQB*0302) tg mice expressing the human major histocompatibility complex II (MHCII) HLA-DQ8 allele on a high proportion of PBL, spleen and lymph node cells were used. …”
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GPD2 inhibition impairs coagulation function via ROS/NF-κB/P2Y12 pathway by Jiajie Chen, Guifeng Xu, Zhipeng Xie, Shaoxia Xie, Wenwei Luo, Shilong Zhong, Weihua Lai

“…Methods We utilized the 850k methylation array to measure DNA methylation levels in blood samples from 47 healthy controls and 93 patients with CHD. …”
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A Novel Algorithm for the Decomposition of Non-Stationary Multidimensional and Multivariate Signals by Roberto Cavassi, Antonio Cicone, Enza Pellegrino, Haomin Zhou

“…Traditional methods, such as Fourier analysis and wavelet transforms, which are effective in handling mono-dimensional stationary signals, struggle with non-stationary datasets and they require the selection of predefined basis functions. …”
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Broadband Silver Ribbon-Embedded Graphene and h-BN Optical Modulator With High Modulation Depth and Extinction Ratio and Low Switching Voltage by Hossein Karimkhani, Hamid Vahed

“…The effect of the gap between the silver nanoribbons is analyzed for the effective refractive index, modulation depth (MD), Extinction Ratio (ER), Figure of Merit (FoM), and loss. …”
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Fermionic quantum simulation on Andreev bound state superlattices by Peter D. Johannsen, Constantin Schrade

“…These Josephson junction arrays implement an effective superlattice of Andreev bound state atoms that can trap individual fermionic quasiparticles and, due to their wave-function overlap, mediate quasiparticles hoppings. …”
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Performance Characteristics of the Magnetic Constrained Layer Damping by A. Baz, S. Poh

“…A new class of surface damping treatment is proposed to provide effective means for attenuating undesirable structural vibrations. …”
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Multi-pathway blood biomarkers to target and monitor multidimensional prevention of cognitive and functional decline (nested in the IN-TeMPO study framed within the world-wide FING... by Gessica Sala, Gessica Sala, Luca Cuffaro, Luca Cuffaro, Luca Cuffaro, Federico Emanuele Pozzi, Federico Emanuele Pozzi, Federico Emanuele Pozzi, Simona Andreoni, Simona Andreoni, Chiara Bazzini, Chiara Bazzini, Elisa Conti, Elisa Conti, Chiara Paola Zoia, Chiara Paola Zoia, Simone Beretta, Simone Beretta, Simone Beretta, Lucio Tremolizzo, Lucio Tremolizzo, Lucio Tremolizzo, Giuseppe Bellelli, Giuseppe Bellelli, Chukwuma Okoye, Chukwuma Okoye, Maria Cristina Ferrara, Annamaria De Luca, Roberta Lenti, Paola Mantuano, Paola Pontrelli, Alessandra Stasi, Giovanni Defazio, Vincenzo Solfrizzi, Lucilla Crudele, Cristina Airoldi, Cristina Airoldi, Ferdinando Chiaradonna, Maria Pia Longhese, Giovanni Messina, Antonino Natalello, Ivan Orlandi, Alessandra Aloisi, Simonetta Capone, Assunta Ingannato, Assunta Ingannato, Benedetta Nacmias, Benedetta Nacmias, Daniela Capello, Francesca Mangialasche, Francesca Mangialasche, Francesca Mangialasche, Carlo Ferrarese, Carlo Ferrarese, Carlo Ferrarese

“…Within this study, we will explore a comprehensive array of established and exploratory blood biomarkers of several pathologic age-related processes, including Alzheimer’s disease (AD), neurodegeneration, inflammation, senescence and sarcopenia, to stratify subject risk and assess the effect of multidomain interventions on biomarkers.Design and participantsApoE4 status and plasma p-tau217 (AD), NfL (neurodegeneration), GFAP and IL-6 (inflammation), GDF-15 (senescence/sarcopenia) will be evaluated in all subjects (n = 1,662) both at the baseline and at the end of the study (12 months). …”
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Linear Simultaneous Equations’ Neural Solution and Its Application to Convex Quadratic Programming with Equality-Constraint by Yuhuan Chen, Chenfu Yi, Jian Zhong

“…According to the electronic architecture of such a GNN, it is known that the performance of the presented GNN could be enhanced by adopting different activation function arrays and/or design parameters. Computer simulation results substantiate that such a GNN could obtain the accurate solution of the QP problem with an effective manner.…”
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Unraveling Cathepsin S regulation in interleukin-7-mediated anti-tumor immunity reveals its targeting potential against oral cancer by Yung-Chieh Chang, Szu-Jung Chen, Shang-Hung Chen, Sheng-Yen Hsiao, Li-Hsien Chen, Chung-Hsing Chen, Chan-Chuan Liu, Ya-Wen Chen, Ko-Jiunn Liu, Shang-Yin Wu, Jui-Mei Chu, Li-Ying Qiu, Wei-Fan Chiang, Hsing-Pang Hsieh, Wen-Yun Hsueh, Jenn-Ren Hsiao, Meng-Ru Shen, Jang-Yang Chang, Kwang-Yu Chang

“…Methods OC patients’ samples were used to disclose the correlation among CTSS and CD8+ T cell infiltration levels. The cytokine array was used to investigate the effect of CTSS on the secretion of cytokine/chemokines. …”
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INJECTING FASTENING LOESS SOILS GROZNY FINE PARTICULATE MATTER SUCH AS «MIKRODUR» by S-A. Y. Murtazaev, M. R. Nahaev, I. J. Kharchenko

“…The paper is devoted to the actual problem of development and implementation of effective ways to increase the bearing capacity of foundations of buildings and structures by impregnating the soil very finely dispersed binders such as "Mikrodur", turning it into a constructive element of the structure.The article shows that the use of a fine binder improves impervious properties strengthened by arrays, resistance to aggressive influences, hardening in a negative temperature, the strength development, etc.…”
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Three-dimensional Orbit and Dynamical Masses of GJ 105 AC by Cayla M. Dedrick, Jason T. Wright, Jason D. Eastman, Cullen H. Blake, Samson A. Johnson, Peter Plavchan, John Asher Johnson, David H. Sliski, Maurice L. Wilson, Robert A. Wittenmyer, Thomas Barclay, Jonathan Horner, Stephen R. Kane, Sharon X. Wang

“…We jointly analyze radial velocity (RV) and relative astrometry data, including new RVs from the Miniature Exoplanet Radial Velocity Array that capture the full periapsis passage and the RV minimum of the 76.0 ± 1.3 yr orbit for the first time. …”
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MIR-4421 AS A POSSIBLE MODULATOR OF MAPK/AKT PATHWAY THROUGH ERP29 IN PHARYNGEAL CANCER by Juliana Carron, Carmen Silvia Passos Lima, Gustavo Jacob Lourenço

“…We identified and validated genes modulated by ERP29 in FaDu and FaDu-R cells by TaqMan plate array and quantitative PCR (qPCR), respectively. …”
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