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3241
Blood exosome connexins and small RNAs related to demyelinating disease activity
Published 2025-03-01“…Control mice showed increased Ex‐GJA1‐43k and ‐29k during EAE; this effect was markedly reduced in Cx43‐icKO mice with attenuated EAE. …”
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3242
The Onset of Feedback in A1885: Evidence for Large-scale Quenching Despite a Young Central Active Galactic Nucleus
Published 2025-01-01“…Including radio data from LOFAR, the Giant Metrewave Radio Telescope, ASKAP, and the Very Large Array, spanning 44 MHz–150 GHz, and optical integral field unit data from the Sloan Digital Sky Survey's MaNGA, we probe the details of cooling, feeding, and feedback in this system. …”
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3243
Unveiling Wolbachia transcriptomic signature in the arboviral vector Aedes aegypti
Published 2025-04-01“…Six datasets were retrieved from Gene Expression Omnibus, Sequence Read Archive and ArrayExpress (last searched in July 2024, considering lack of replication as the exclusion criteria). …”
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3244
MCAM interacts with integrin β1 to promote EGFR-TKI resistance in lung adenocarcinoma through the JAK3 signalling pathway
Published 2025-07-01“…Furthermore, receptor tyrosine kinase (RTK) phosphorylation antibody array, co-immunoprecipitation, immunofluorescence, and dual-luciferase assay were employed to elucidate its molecular mechanism. …”
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3245
Common and rare variant analyses implicate late-infancy cerebellar development and immune genes in ADHD
Published 2025-06-01“…In low-frequency / rare variant analyses, we discovered the correlations between ADHD and collapsing effects of rare damaging variants in TEP1, MTMR10, DBH, TBCC, and ANO1. …”
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3246
An Efficient Design Approach for a Broadband E-Plane Five-Way Power Divider/Combiner in Rectangular Waveguide
Published 2025-01-01“…This design serves as an effective solution for odd-number power dividers, achieving performance metrics that are rarely seen in the literature. …”
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3247
Ferroptosis-related genes participate in the microglia-induced neuroinflammation of spinal cord injury via NF-κB signaling: evidence from integrated single-cell and spatial transcr...
Published 2025-01-01“…Reduced inflammatory responses and microglial ferroptosis were potential effects of NT3-chitosan or LDH-NT3 on neuronal regeneration. …”
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3248
Isolation and Identification of Aglicones of Flavonoids of Some Species of the Genus <i>Astragalus</i> L. of the Volga Region Flora
Published 2023-02-01“…Expansion of the nomenclature of medicinal plant materials and the study of BAS groups that determine the main pharmacological effects are topical studies in pharmacognosy. From this point of view, little-studied species of Astragalus (Astragalus henningii (Stev.) …”
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3249
Downregulation of exosomal miR-let-7e-5p induces macrophage M2 polarization by targeting Rictor/AKT1 signal pathway in brucellosis patients
Published 2025-07-01“…Macrophage polarization was confirmed using flow cytometry and cytometric bead array (CBA). The expression levels of miR-let-7e-5p and Rictor were quantified using quantitative reverse transcription polymerase chain reaction (qRT-PCR). …”
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3250
Tomografía geoeléctrica: dos ejemplos en la Sabana de Bogotá
Published 2000-08-01“…The reached depths of investigation were 30% for the first example and 40%, for the second, situating the electrodes with Wenner amd Wenner-Sciumberguer arrays. Using the results of these two examples, clearly we can see that the depth of investigation depends on the media, the geometric array and the lenght of the section. …”
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3251
Maternal dysglycaemia, changes in the infant's epigenome modified with a diet and physical activity intervention in pregnancy: Secondary analysis of a randomised control trial.
Published 2020-11-01“…Cord blood DNA samples from the infants were interrogated for genome-wide DNA methylation levels using the Infinium Human MethylationEPIC BeadChip array. Robust regression was carried out, adjusting for maternal age, smoking, parity, ethnicity, neonate sex, and predicted cell-type composition. …”
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3252
Interleukin-30 feeds breast cancer stem cells via CXCL10 and IL23 autocrine loops and shapes immune contexture and host outcome
Published 2021-10-01“…Their autocrine loops mediate much of the CSC growth factor activity of IL30, while their paracrine effect contributes to IL30 shaping of immune contexture. …”
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3253
COPB2 as a key regulator of cell growth in human osteosarcoma cells: Potential therapeutic target and prognostic indicator
Published 2025-08-01“…Furthermore, the regulation mechanism of COPB2 on osteosarcoma cells was investigated using the Human Phospho-Kinase Array Kit. Results: Patients with high COPB2 expression exhibited shorter overall survival and disease-free survival compared to those with low COPB2 expression. …”
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3254
Keratinocyte-derived VEGF-A is an essential pro-migratory autocrine mediator, acting through the KDR/GEF-H1/RhoA pathway
Published 2025-07-01“…Key proteins were visualized using immunohistochemistry in an MC903-induced mouse model of atopic dermatitis.ResultsWe showed that keratinocytes secreted an array of soluble factors, including VEGF-165. Secretion of VEGF-165 was augmented by TNFα through SP1, HIF1α and NFκB. …”
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3255
Technology-Based HIV Prevention Interventions for Men Who Have Sex With Men: Systematic Review and Meta-Analysis
Published 2025-04-01“…ConclusionsTechnology-based HIV prevention interventions are promising strategies to improve HIV testing uptake and consistent condom use among men who have sex with men in China, with significant effects found across a broad array of studies and study designs. …”
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3256
Seismic Mitigation Performance and Damage of Prefabricated Base Isolation Structure Based on the Shaking Table Test
Published 2025-01-01“…At present, strengthening the design of beam-column assembly joints and adopting seismic isolation techniques are two different ways to achieve this goal. As an effective means to prevent earthquakes, the seismic isolation technology can effectively reduce the seismic action of the prefabricated reinforced concrete frame structure system. …”
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3257
Modeling Factors Influencing Project Financing Risk
Published 2024-03-01“…Diving deeper into the realm of project financing, one finds a diverse array of financing mechanisms, each characterized by its unique set of risks and complex capital structures. …”
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3258
MMAgentRec, a personalized multi-modal recommendation agent with large language model
Published 2025-04-01“…This integration enables systems to support a broader array of inputs, facilitating seamless dialogues and coherent responses. …”
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3259
Analysis of molecular mechanisms of the development of experimental diabetes in Wistar rats under conditions of intermittent hypoxia
Published 2023-11-01“…This approach holds promise for effectively managing and enhancing diabetes outcomes, as it has the potential to influence metabolism and physiological processes within the body significantly. …”
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3260
The role of apology beliefs for apology tendencies across cultures with varying honor norms
Published 2025-01-01“…Complementary analyses comparing regional categorizations (Anglo-West, East Asia, and MENA) further supported a picture of relative cultural similarities but also highlighted a wider array of relevant apology beliefs in the MENA region as well as a greater focus on personal morality beliefs in Anglo Western societies and personal effectiveness beliefs in East Asian societies. …”
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