Phytochemical Analysis and Biological Activities of Flavonoids and Anthraquinones from <i>Cassia alata</i> (Linnaeus) Roxburgh and Their Implications for Atopic Dermatitis Manageme... by Sue-Kei Lee, Jing-Wen Keng, Jessica-Ai-Lyn Yon, Chun-Wai Mai, Heng-Chee Lim, Sek-Chuen Chow, Gabriel Akyirem Akowuah, Kai Bin Liew, Siew-Keah Lee, Philip J. Marriott, Yik-Ling Chew

“…To study <i>Cassia alata</i> (CA) (Linnaeus) Roxburgh’s effectiveness towards atopic dermatitis (AD), CA leaf extracts were prepared using three methanol-based extraction solvent systems. …”
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First demonstration of a TES based cryogenic Li $$_2$$ 2 MoO $$_4$$ 4 detector for neutrinoless double beta decay search by G. Bratrud, C. L. Chang, R. Chen, E. Cudmore, E. Figueroa-Feliciano, Z. Hong, K. T. Kennard, S. Lewis, M. Lisovenko, L. O. Mateo, V. Novati, V. Novosad, E. Oliveri, R. Ren, J. A. Scarpaci, B. Schmidt, G. Wang, L. Winslow, V. G. Yefremenko, J. Zhang, D. Baxter, M. Hollister, C. James, P. Lukens, D. J. Temples

“…The largest planned detector array, CUPID, is comprised of about 1500 individual Li $$_{2}$$ 2 $$^{100}$$ 100 MoO $$_4$$ 4 detector modules with a further scale up envisioned for a follow up experiment (CUPID-1T). …”
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Sol-gel synthesized CoFe2-xGdxO4:SiO2 nanocomposites for structural, thermal and magnetic investigation by Meenakshi Bansal, Dharamvir Singh Ahlawat, Amrik Singh, Shish Pal Rathee, Vijay Kumar, Anjali Maan, Mahipal Singh

“…Appearance of bands in FTIR spectra at 860.09 cm−1, 586.57 cm−1 and an array of 559–580 cm−1 are contributed by Si–O–Fe vibrations and absorption bands of Gd3+ respectively. …”
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Knockdown of the long noncoding RNA VSIG2-1:1 promotes the angiogenic ability of human pulmonary microvascular endothelial cells by activating the VEGF/PI3K/AKT pathway by Xiaoya Hu, Yihui Zheng, Mingchu Fang, Zhongjie Liang, Chao Wen, Jing Lin, Zhenlang Lin, Shangqin Chen

“…Although numerous factors have been suggested to control the development of pulmonary blood vessels, the mechanisms underlying the role of long noncoding RNAs (lncRNAs) in this process remain unclear. Methods A lncRNA array was used to measure the differential expression of lncRNAs in premature infants with and without BPD. …”
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Ecological impacts of single-axis photovoltaic solar energy with periodic mowing on microclimate and vegetation by Yudi Li, Yudi Li, Alona Armstrong, Alona Armstrong, Christopher Simmons, Noah Z. Krasner, Noah Z. Krasner, Rebecca R. Hernandez, Rebecca R. Hernandez, Rebecca R. Hernandez, Rebecca R. Hernandez

“…Compared to open spaces, vegetation near and within the PV array footprint displayed greater species richness (+8.4%), taller maximum height (+21%), reduced coverage of sun-loving plants (−71%), and less dead biomass accumulation (−26%), from shade-driven effects. …”
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Replication of European hypertension associations in a case-control study of 9,534 African Americans. by Harpreet Kaur, Dana C Crawford, Jingjing Liang, Penelope Benchek, COGENT BP Consortium, Xiaofeng Zhu, Asha R Kallianpur, William S Bush

“…In this study, we examined a large AA cohort for the generalizability of 14 Metabochip array SNPs with previously reported European hypertension associations.…”
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Bordetella adenylate cyclase toxin elicits chromatin remodeling and transcriptional reprogramming that blocks differentiation of monocytes into macrophages by Jawid Nazir Ahmad, Martin Modrak, Marketa Fajfrova, Blanca Martin-Borja Sotoca, Oldrich Benada, Peter Sebo

“…ABSTRACT Bordetella pertussis infects human upper airways and deploys an array of immunosuppressive virulence factors, among which the adenylate cyclase toxin (CyaA) plays a prominent role in disarming host phagocytes. …”
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DNA methylation biomarker panels for differentiating various liver adenocarcinomas, including hepatocellular carcinoma, cholangiocarcinoma, colorectal liver metastases and pancreat... by Tina Draškovič, Branislava Ranković, Nina Zidar, Nina Hauptman

“…Reevaluation of the same bioinformatic data with new additional CRLM projects demonstrated that the lower dPCR methylation threshold still effectively differentiates between the included cancer types. …”
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Comparative Evaluation of Efficacy and Complications Between Biportal Endoscopic Lumbar Interbody Fusion and Minimally Invasive Transforaminal Lumbar Interbody Fusion for Lumbar De... by Hu Q, Xiao K, Nan JN, Jhang SW, Chen CM, Lin GX

“…The evaluative framework encompassed a diverse array of parameters, including but not limited to operation time, hospitalization, quantification of estimated blood loss, the assessment of outcomes via the application of the Visual Analog Scale (VAS) to gauge pain intensity, and the utilization of the Oswestry Disability Index (ODI) to measure functional impairment.Results: The current meta-analysis included ten studies with a total of 736 participants. …”
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Changes in DNA methylation are associated with systemic lupus erythematosus flare remission and clinical subtypes by Mary K. Horton, Joanne Nititham, Kimberly E. Taylor, Patricia Katz, Chun Jimmie Ye, Jinoos Yazdany, Maria Dall’Era, Charlotte Hurabielle, Lisa F. Barcellos, Lindsey A. Criswell, Cristina M. Lanata

“…Methylation was measured using the Illumina EPIC array. We identified sites where methylation change between visits was associated with remission at the follow-up visit using limma package and a time x remission interaction term. …”
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Isolation of Individual Compounds from the Terrestrial Parts of Ononis Arvensis L. and Solidago Canadensis L. by V. G. Luzhanin, A. K. Whaley, A. O. Ponkratova, E. A. Grishukova, I. S. Suloev, S. N. Smirnov, E. B. Serebryakov

“…At the same time, synthetic diuretics which are widely used, cause large amounts of side effects, such as violation of electrolyte, acid-base and water balances, carbohydrate and lipid metabolism. …”
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Analysis of Milling Performance of High-Entropy Alloys with Different Elemental Ratios Subject to the Assistance of Various Ultrasonic Systems by Shen-Yung Lin, Bo-Chun Chen

“…Based on the results of the first phase, the better ultrasonic-assisted milling technique is selected and an L₉ Taguchi orthogonal array is then employed for process parameter planning, by varying spindle speed, feed rate, and radial cutting depth to investigate the effects of different process parameter combinations on machining performance of HEAs with different elemental ratios. …”
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Process parameter optimization for minimizing overcut in abrasive waterjet deep hole drilling of SS 316L by J. Bharani Chandar, N. Lenin, Alagar Karthick, Pradeep Kumar Singh, M. Siva Kumar, Md Irfanul Haque Siddiqui, Intesaaf Ashraf, Saurav Dixit, Nikolai Ivanovich Vatin, Choon Kit Chan

“…The deep hole drilling experiments have been conducted utilizing Taguchi’s (L16) orthogonal array by adjusting the drilling settings. The statistical significance of specific drilling parameters and second-order quadratic models for the responses have been established by analysis of variance. …”
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A bovine model of rhizomelic chondrodysplasia punctata caused by a deep intronic splicing variant in the GNPAT gene by Arnaud Boulling, Julien Corbeau, Cécile Grohs, Anne Barbat, Jérémy Mortier, Sébastien Taussat, Vincent Plassard, Hélène Leclerc, Sébastien Fritz, Cyril Leymarie, Lorraine Bourgeois-Brunel, Alain Ducos, Raphaël Guatteo, Didier Boichard, Mekki Boussaha, Aurélien Capitan

“…For verification, we performed large-scale genotyping of this variant using a custom SNP array and found a perfect genotype–phenotype correlation in 21 cases and 26 of their parents, and a complete absence of homozygotes in 1195 unaffected Aubrac controls. …”
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VF arrest secondary to immune checkpoint inhibitor (ICI)-associated myocarditis; improving patient outcomes by maintaining a high clinical suspicion for ICI toxicity by Victoria Floyd-Ellis

“…Introduction: Use of immune checkpoint inhibitor (ICI) medications has revolutionised clinical outcomes and remains an exciting prospect in oncology as further indications are revealed.1 However, adverse effects, or toxicities, secondary to their non-targeted immunological activation create an array of complications that require prompt recognition and management not only by oncologists, but also all clinicians.2This case highlights the often subtle, non-specific presentation of ICI toxicities that reveal significant pathological processes and consequences for patients. …”
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Longitudinal insights into maternal body composition across trimesters of pregnancy by Mugdha Deshpande, Neha Kajale, Nikhil Shah, Ketan Gondhalekar, Vivek Patwardhan, Anagha Pai Raiturker, Sanjay Gupte, Leena Patankar, Anuradha Khadilkar

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CNDP1, NOS3, and MnSOD Polymorphisms as Risk Factors for Diabetic Nephropathy among Type 2 Diabetic Patients in Malaysia by Mohd Jokha Yahya, Patimah Binti Ismail, Norshariza Binti Nordin, Abdah Binti Md Akim, Wan Shaariah Binti Md Yusuf, Noor Lita Binti Adam, Nurul Fasihah Zulkifli

“…DNA sequencing was performed for the D18S880 of CNDP1, while the rest were tested using DNA Sequenom MassARRAY to identify the polymorphisms. DNA was extracted from the secondary blood samples taken from the T2DM patients. …”
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Experimental Investigation on Thermal Performance Optimization of Na₂HPO₄·12H₂O-Based Gel Phase Change Materials for Solar Greenhouse by Wenhe Liu, Gui Liu, Wenlu Shi, Xinyang Tang, Xuhui Wu, Jiayang Wu, Zhanyang Xu, Feng Zhang, Mengmeng Yang

“…Using the Taguchi method with an L₂₇(3¹³) orthogonal array, multi-step melt–blending experiments were conducted to prepare a novel multi-component phase change material. …”
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Eco-friendly QbD-optimized chromatographic method for simultaneous analysis of metronidazole and nicotinamide with applications in permeation, stability, and sustainability evaluat... by Kanaka Parvathi Kannaiah, Mohamed A. M. Ali, Hemanth Kumar Chanduluru, Anis Ahmad Chaudhary, Mahmoud El-Maghrabey, Reem H. Obaydo, Galal Magdy, Mohamed A. El Hamd

“…Chromatographic separations were conducted with an RP-HPLC-photodiode array (PDA) system equipped with an ODS column using gradient elution of ethanol and phosphate buffer (10 mM, pH 3.5) at a flow rate of 1.0 mL/min. pre-optimized conditions were determined using a two-level full factorial design (23 FFD). …”
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2-Amino-3-Chlorobenzoic Acid from <i>Streptomyces coelicolor</i>: A Cancer Antagonist Targeting PI3K/AKT Markers via miRNA Modulation by Ashraf Khalifa, Joseph D. Balthazar, Pandurangan Subash-Babu, Mohamed Y. Zaky, Zeinab A. El-Moaty, Hairul Islam M. Ibrahim

“…<b>Background/Objectives:</b> Actinomycetes, particularly species within the <i>Streptomyces</i> genus, are renowned for their ability to produce a wide array of bioactive molecules with therapeutic potential. …”
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