Using the Taguchi method and grey relational analysis to optimize the parameter design of flat-plate collectors with nanofluids, and phase change materials in an integrated solar w... by Guan-Rong Chen, Ting-Wei Liao, Chien-Chun Hsieh, Jagadish Barman, Chao-Yang Huang, Chung-Feng Jeffrey Kuo

“…A total of 36 experiments were designed using the Taguchi orthogonal array and simulated through TRNSYS software. Data from these experiments were analyzed using Signal-to-Noise (S/N) ratios, main effects analysis, and analysis of variance to identify optimal parameter combinations. …”
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Changes of cytokine profile measures during the treatment of rheumatoid arthritis with rituximab biosimilar (Acellbia, BIOCAD) and the original drug (MabThera, F. Hoffmann-La Roche... by A. S. Avdeeva, A. S. Artyukhov, E. B. Dashinimaeva, M. V. Cherkasova, E. L. Nasonov

“…The concentration of 27 cytokines in blood serum was determined by multiplex xMAP technology on the analyzer Bio-Plex Array System (BIO-RAD, USA). Results and discussion. …”
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Caregiver-child interaction and early childhood development among preschool children in rural China: the possible role of blood epigenome-wide DNA methylation by Mengna Wei, Rui Chang, Chunan Li, Yanfen Jiang, Jianduan Zhang

“…Of the 171 children aged 3–6 years who participated in ECD assessment and blood samples collection, a total of 64 were selected for epigenome-wide association study with Illumina Infinium MethylationEPIC v1.0 BeadChip array (850 K). The linear regression model in the R package “CpGassoc”was applied to identify CpG sites associated with global NDS and caregiver-child interaction. …”
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Salt Stress Leads to Morphological and Transcriptional Changes in Roots of Pumpkins (<i>Cucurbita</i> spp.) by Hongjiu Liu, Ding Ding, Yeshuo Sun, Ruiping Ma, Xiaoqing Yang, Jie Liu, Guoxin Zhang

“…To deal with salt stress, plants exhibit an array of responses such as changes in their root system architecture. …”
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Alum-anchored IL-12 combined with cytotoxic chemotherapy and immune checkpoint blockade enhanced antitumor immune responses in head and neck cancer models by James W Hodge, Howard Kaufman, Michelle R Padget, Kellsye P Fabian, Sailaja Battula, Wiem Lassoued, Ginette Santiago-Sanchez, Clint Tanner Allen

“…For MOC1, flow cytometry and cytokine array were performed to assess the immune effector functions associated with the combinational treatment. …”
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Transcutaneous auricular vagus nerve stimulation alleviates inflammation-induced depression by modulating peripheral-central inflammatory cytokines and the NF-κB pathway in rats by Xingke Song, Haohan Zhu, Zijie Chen, Yifei Wang, Jinling Zhang, Yu Wang, Peijing Rong, Junying Wang

“…ObjectivesThis study aims to investigate the mechanisms of transcutaneous auricular vagus nerve stimulation (taVNS) in a lipopolysaccharide (LPS)-induced acute inflammatory depression model in rats, focusing on the regulation of peripheral pro- and anti-inflammatory cytokines and the effects on the NF-κB signaling pathway in the prefrontal cortex.MethodsA depressive-like behavior model was established via intraperitoneal injection of LPS, and rats were randomly assigned to a normal group, a model group, and a taVNS intervention group. …”
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DFT analysis of the [3 + 2] heterocyclization reaction of ((1,2,4-triazole(1,3,4-oxadiazole)-3(2)-yl)methyl)thiopyrimidines by Yu. V. Karpenko

“…Particular attention was given to the influence of electronic and steric effects on the stability of the resulting heterocycles. …”
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How can Blood Flow Restriction Exercise be Utilised for the Management of Persistent Pain Following Complex Injuries in Military Personnel? A Narrative Review by Luke Gray, Peter Ladlow, Russell J Coppack, Robyn P Cassidy, Lynn Kelly, Sarah Lewis, Nick Caplan, Robert Barker-Davies, Alexander N Bennett, Luke Hughes

“…Abstract Background Persistent pain is a complicated phenomenon associated with a wide array of complex pathologies and conditions (e.g., complex regional pain syndrome, non-freezing cold injury), leading to extensive disability and reduced physical function. …”
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BRD4 short isoform interacts with RRP1B, SIPA1 and components of the LINC complex at the inner face of the nuclear membrane. by Jude Alsarraj, Farhoud Faraji, Thomas R Geiger, Katherine R Mattaini, Mia Williams, Josephine Wu, Ngoc-Han Ha, Tyler Merlino, Renard C Walker, Allen D Bosley, Zhen Xiao, Thorkell Andresson, Dominic Esposito, Nicholas Smithers, Dave Lugo, Rab Prinjha, Anup Day, Nigel P S Crawford, Keiko Ozato, Kevin Gardner, Kent W Hunter

“…Recent studies suggest that BET inhibitors are effective anti-cancer therapeutics. Here we show that BET inhibitors are effective against murine primary mammary tumors, but not pulmonary metastases. …”
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The interplay of cancer-associated fibroblasts and apoptotic cancer cells suppresses lung cancer cell growth through WISP-1-integrin ανβ3-STAT1 signaling pathway by Shinyoung Kim, Kyungwon Yang, Kiyoon Kim, Hee Ja Kim, Da Young Kim, Jeesoo Chae, Young-Ho Ahn, Jihee Lee Kang

“…Methods Experimental methods including CCK assay, colony formation assay, immunoblotting, co-immunoprecipitation, qRT-PCR analysis, qRT-PCR array, apoptosis assay, ELISA, and immunofluorescent staining were used in this study. …”
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Polymorphism in Genes Encoding HSP40 Family Proteins is Associated with Ischemic Stroke Risk and Brain Infarct Size: A Pilot Study by Ksenia A. Kobzeva, Denis E. Gurtovoy, Alexey V. Polonikov, Vladimir M. Pokrovsky, Evgeny A. Patrakhanov, Olga Y. Bushueva

“…In interactions with the studied SNPs, smoking was found to have multidirectional effects (synergism, antagonism or additive effect) and the strongest mono-effect (3.47% of IS entropy), exceeding the mono-effects of rs6500605 DNAJA3, rs10448231 DNAJA1, rs2034598 DNAJA2, rs7189628 DNAJA2 and rs4926222 DNAJB1, involved in the best G×E models and determining 0.03%–0.73% of IS entropy. …”
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Text Messaging to Extend School-Based Suicide Prevention: Pilot Randomized Controlled Trial by Anthony R Pisani, Peter A Wyman, Ian Cero, Caroline Kelberman, Kunali Gurditta, Emily Judd, Karen Schmeelk-Cone, David Mohr, David Goldston, Ashkan Ertefaie

“…A key challenge within schoolwide programs is reaching a large and diverse array of students, especially those less engaged with their peers. …”
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Exploring the Mechanism of 2&amp;#x02B9;-Hydroxychalcone Improving Copper Sulfate-Induced Inflammation in Zebrafish Through Network Pharmacology by Shen Y, Yao YD, Li H, Zhang Q, Wang CL, Hu L, Hu YC, Chen MH

“…Its effect on zebrafish behavior ability and the change trend of oxidative stress index were explored by changing the functional state of the target, such as changing the functional activity of the target by micro-injection technology. …”
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Inhibition Kinetics of LMWF on α-Amylase and α-Glucosidase and Its Application in Low-GI Milk Powders by Yao LI, Yitian JIA, Jinyue WANG, Yunhai HE, Dandan REN, Shu LIU

“…Results demonstrated that UF (Fucoidan from Undaria pinnatifida Suringar) and EUF obtained by enzymatic degradation of UF (Enzymatic degradation of UF, EUF) exerted significant inhibitory effects on both α-amylase and α-glucosidase, and the effects of EUF were observed to be stronger than that of UF, which indicated that the activity of fucoidan was enhanced after degradation. …”
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Ectomycorrhizal fungal community succession and fragmentation across forest edges nearly three decades postharvest by Olivia M. Rianhard, J. Marty Kranabetter, Latina V. Penkova, Daniel M. Durall, Melanie D. Jones

“…Overall, the potential benefits of small openings were apparently constrained by environmental factors that delay the re‐establishment of late‐seral EMF species under open canopies. The negative effect of edges on EMF reproduction and some taxa abundance in the forest adjacent to openings is relevant when designing green‐tree retention forestry systems, suggesting medium to large patches of trees may reduce fragmentation stress and better sustain an array of late‐seral fungi.…”
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Nitric oxide modulates contrast suppression in a subset of mouse retinal ganglion cells by Dominic Gonschorek, Matías A Goldin, Jonathan Oesterle, Tom Schwerd-Kleine, Ryan Arlinghaus, Zhijian Zhao, Timm Schubert, Olivier Marre, Thomas Euler

“…In this study, we used two-photon Ca2+ imaging and multi-electrode array (MEA) recordings to measure light-evoked activity of RGCs in the ganglion cell layer in the ex vivo mouse retina. …”
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Let-7a-5p derived from parathyroid hormone (1–34)-preconditioned BMSCs exosomes delays the progression of osteoarthritis by promoting chondrocyte proliferation and migration by Litao Shao, Lu Ding, Weizhao Li, Chi Zhang, Yu Xia, Miaoyu Zeng, Zhizhong Ye, David Y. B. Deng

“…By performing a miRNA array, RNA-seq, in addition to bioinformatic analysis, the miRNA and the potential regulatory mechanism were detected. …”
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Downregulation of EB1 impedes Cx43 localization and cardiac conduction after hypothermic ischemia-reperfusion in rats by Chunlei Wen, Rongfeng Yang, Jing Yi, Ying Cao, Yuting Song, Li An, Zijun Wang, Hong Gao

“…After 4 weeks, untreated rat hearts underwent continuous isolated heart perfusion for 5 min, while the treatment groups were subjected to Langendorff isolated heart ischemia-reperfusion. The multi-electrode array (MEA) technique was used to measure the conduction heterogeneity of rat heart, evaluating the protective effects of EB1 overexpression against reperfusion arrhythmias. …”
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Proteostasis Decline and Redox Imbalance in Age-Related Diseases: The Therapeutic Potential of NRF2 by Brigitta Buttari, Antonella Tramutola, Ana I. Rojo, Niki Chondrogianni, Sarmistha Saha, Alessandra Berry, Letizia Giona, Joana P. Miranda, Elisabetta Profumo, Sergio Davinelli, Andreas Daiber, Antonio Cuadrado, Fabio Di Domenico

“…Nuclear factor erythroid 2-related factor 2 (NRF2) is a master regulator of cellular homeostasis, overseeing the expression of a wide array of genes involved in cytoprotective processes such as antioxidant and proteostasis control, mitochondrial function, inflammation, and the metabolism of lipids and glucose. …”
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Trade-off analysis of machinability of steel alloy AISI 304L using Taguchi-grey integrated approach by Faisal Abbas, Muhammad Ali Khan, Muhammad Iftikhar Faraz, Syed Husain Imran Jaffery, Sohail Akram, Jana Petru, Refka Ghodhbani, Walid M. Shewakh

“…Efficient Taguchi design of experimentation was employed for formulation of L16 orthogonal array. Effect of each cutting parameter on the response variables was investigated using main effects plot and analysis of variance was done to ascertain influence of each input through its contribution ratio. …”
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