Inhibition of colorectal carcinogenesis by sunitinib malate: disruption of the IL-6/STAT3/c-MYC/TWIST/MMP2 autocrine signaling axis by Ling Qian, Yi Yang, Bin Zhao, Pan Xu, Ziyan Hu, Liangwang Zhong, Qi Dai, Youbao Zhong, Chao Yang, Qinglong Shu, Ray P. S. Han, Yang Guan, Zhiming Li, Lai Chen

“…We employed a comprehensive array of experimental techniques, including CCK-8/MTT assays for cell viability, Transwell and/or wound healing assays for migration, and Western blot and immunohistochemistry for protein expression analysis. …”
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Genetic polymorphisms in MIR1208 and MIR5708 are associated with susceptibility to COPD in the Chinese population by Y. Zhou, F. Bai, X. Li, G. Zhou, X. Tian, G. Li, Y. Zhang, X. Zhou, D. Xu, Y. Ding

“…The purpose of this study was to investigate the effects of gene polymorphisms in MIR5708 and MIR1208 on COPD risk.Methods Four single nucleotide polymorphisms (SNPs) in MIR5708 (rs6473227 and rs16907751) and MIR1208 (rs2608029 and rs13280095) were selected and genotyped among 315 COPD patients and 314 healthy controls using the Agena MassARRAY platform. …”
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A Multifrequency Census of 100 Pulsars below 100 MHz with LWA: A Systematic Study of Flux Density, Spectra, Timing, Dispersion, Polarization, and Its Variation from a Decade of Obs... by P. Kumar, G. B. Taylor, K. Stovall, J. Dowell, S. M. White

“…We present a census of 100 pulsars, the largest below 100 MHz, including 94 normal pulsars and six millisecond pulsars, with the Long Wavelength Array (LWA). Pulse profiles are detected across a range of frequencies from 26–88 MHz, including new narrowband profiles facilitating profile evolution studies, and breaks in pulsar spectra at low frequencies. …”
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T‐cell differentiation stage block bias confers hypermethylation and mediastinal preference in T‐cell lymphoblastic lymphoma by Jiali Wang, Bo Qian, Xiaowen Yu, Yidan Zhang, Chunlei Zhou, Tingting Yang, Le Xia, Gang Zhang, Yi‐Xuan Zhang, Yaping Wang, Yongjun Fang

“…Combining the single‐cell RNA sequencing data of T‐ALL, expression array data, flow cytometry data, we discovered that malignant T cells in T‐LBL are predominantly in the DN‐ and DP‐stage blocking modes (DP cells dominate). …”
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Inflammatory response to chronic nicotine-containing electronic cigarette exposure in a rat model of myocardial infarction by Jianru Shi, Wangde Dai, Juan Carreno, Jaspreet Sachdeva, Jesus Chavez, Michael T. Kleinman, David A. Herman, Rebecca J. Arechavala, Irene Hasen, Amanda Ting, Robert A. Kloner

“…Introduction The long-term effects of chronic electronic cigarette (e-cigarette) exposure on lung and heart inflammation during the healing phase of myocardial infarction (MI) remain unexplored. …”
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Optimizing Bitumen Performance in Warm Mix Asphalt Using Cecabase RT BIO10: A Taguchi-Based Experimental Approach by Mustafa Çakı, Fatih İrfan Baş

“…The experimental design employed a Taguchi L16 orthogonal array to systematically evaluate the effects of various factors on modified bitumen performance. …”
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Bioactive constituents from the edible seaweed Halymenia hawaiiana (Rhodophyta) by Achara Raksat, Md Samiul Huq Atanu, Karla J. McDermid, Marisa M. Wall, Boon Loong Chang, Supakit Wongwiwatthananukit, Leng Chee Chang

“…These compounds also effectively inhibited the generation of reactive oxygen species (ROS)/reactive nitrogen species (RNS) in RAW 264.7 mouse macrophage cells with IC50 values of 55–73.7 µM without inducing cytotoxicity. …”
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Amygdala aromatase controls food intake, reward, and thermoregulation by Ivana Maric, Jennifer E. Richard, Lilly Taing, Suyeun Byun, Lorena Lopez-Ferreras, Yifan Qiu, Karolina P. Skibicka

“…This was driven by opposing effects on food preference for a high-fat diet. Amygdala aromatase knockdown was sufficient to increase feeding and body weight in lean and obese females, with increased visceral adiposity; effects not observed in males. …”
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Systemic stem cell treatment rescues injured motoneurons by reducing L-selectin expression on leukocytes by Tamás Bellák, Zoltán Fekécs, Dénes Török, Rebeka Kristóf, Omoikhoje Esezoobo, Annamária Marton, Csaba Vizler, Antal Nógrádi, Krisztián Pajer

“…The molecular changes within the treated cord were followed by the ELISA Proteome Profiler rat cytokine array and qPCR analysis. To mimic the effect of stem cells fucoidan treatment (a specific selectin inhibitor, 50 and 100 mg/kg bw) was applied for two weeks intraperitoneally. …”
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Thermoresistant flagellin-adjuvanted cancer vaccine combined with photothermal therapy synergizes with anti-PD-1 treatment by Jayalakshmi Thiruppathi, Veena Vijayan, Yong Jun Bang, Hye Suk Hwang, Shee Eun Lee, Joon Haeng Rhee, Vandara Loeurng, Seol Hee Hong, Aravindkumar Sundaram, In-Kyu Park

“…Immune checkpoint inhibitors (ICIs) are used in a wide array of cancers, but only a limited fraction of patients are responding. …”
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Xenobiotic-induced liver injury: Molecular mechanisms and disease progression by Lu Wang, Zigong Shao, Xiaobei Wang, Wenqiu Lu, Hong Sun

“…Environmental xenobiotics comprising a wide array of natural and synthetic chemicals are an escalating global health concern due to their persistent presence in ecosystems and their profound impact on human liver health. …”
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Sleep disturbances, shift work, and epigenetic ageing in working-age adults: findings from the Young Finns study by Ida Autio, Aino Saarinen, Saara Marttila, Emma Raitoharju, Pashupati P. Mishra, Nina Mononen, Mika Kähönen, Liisa Keltikangas-Järvinen, Olli Raitakari, Terho Lehtimäki

“…Abstract Background Sleep disturbances are known to have adverse effects on health, but knowledge on the effect of sleep disturbances on epigenetic ageing is limited. …”
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Genome‐wide association studies on resistance to powdery mildew in cultivated emmer wheat by Dhondup Lhamo, Genqiao Li, George Song, Xuehui Li, Taner Z. Sen, Yong‐Qiang Gu, Xiangyang Xu, Steven S. Xu

“…Most novel loci exhibited minor effects, whereas three novel loci on chromosome arms 2AS, 3BS, and 5AL had major effect on the phenotypic variance. …”
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A Performance Study of Dielectric Metalens with Process-Induced Defects by Yanyan Zhou, Ting Hu, Yu Li, Nanxi Li, Yuan Dong, Dongdong Li, Yuan Hsing Fu, Qize Zhong, Zhengji Xu, Shiyang Zhu, Qunying Lin, Navab Singh

“…Potential solutions to mitigate the effect of the process-induced defects are also investigated. …”
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Dolomedes fishing spider biology: gaps and opportunities for future research by Kuang-Ping Yu, Kuang-Ping Yu, Zita Roithmair, Jillian Kurovski, Simon J. Connolly, Cor J. Vink, James Chadwick Johnson, Simona Kralj-Fišer, Simona Kralj-Fišer, Matjaž Kuntner, Matjaž Kuntner, Matjaž Kuntner, Matjaž Kuntner, Eileen A. Hebets, Christina J. Painting, Christina J. Painting

“…We outline a roadmap for future studies that, in our view, will consolidate Dolomedes as an ideal model lineage among spiders for addressing a vast array of questions across multiple fields of biology.…”
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Vacancy-induced suppression of charge density wave order and its impact on magnetic order in kagome antiferromagnet FeGe by Mason L. Klemm, Saif Siddique, Yuan-Chun Chang, Sijie Xu, Yaofeng Xie, Tanner Legvold, Mehrdad T. Kiani, Xiaokun Teng, Bin Gao, Feng Ye, Huibo Cao, Yiqing Hao, Wei Tian, Hubertus Luetkens, Masaaki Matsuda, Douglas Natelson, Zurab Guguchia, Chien-Lung Huang, Ming Yi, Judy J. Cha, Pengcheng Dai

“…Abstract Two-dimensional (2D) kagome lattice metals are interesting because their corner sharing triangle structure enables a wide array of electronic and magnetic phenomena. Recently, post-growth annealing is shown to both suppress charge density wave (CDW) order and establish long-range CDW with the ability to cycle between states repeatedly in the kagome antiferromagnet FeGe. …”
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Epicardial Adipose Tissue: A Multimodal Imaging Diagnostic Perspective by Giancarlo Trimarchi, Maria Ludovica Carerj, Concetta Zito, Gianluca Di Bella, Giovanni Taverna, Maurizio Cusmà Piccione, Pasquale Crea, Stefania Lo Giudice, Angela Buonpane, Michela Bonanni, Davide Restelli, Umberto Paradossi, Angelo Monteleone, Antonio Micari, Scipione Carerj

“…EAT secretes a notable array of bioactive molecules known as adipokines, which exert critical exocrine and paracrine effects. …”
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A standardized fold change method for microarray differential expression analysis used to reveal genes involved in acute rejection in murine allograft models by Weichen Zhou, Yi Wang, Masayuki Fujino, Leming Shi, Li Jin, Xiao‐Kang Li, Jiucun Wang

“…SFC gave better reproducibility than Limma and the t test with real experimental data from the MicroArray Quality Control platform and expression data from a mouse cardiac allograft. …”
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The CHILES Continuum and Polarization Survey. II. Radio Continuum Source Catalog and Radio Properties by Hansung B. Gim, Min S. Yun, Nicholas M. Luber, Emmanuel Momjian, D. J. Pisano, Kelley M. Hess, Julia Blue Bird, Lucas Hunt

“…The COSMOS H I Large Extragalactic Survey (CHILES) Continuum and Polarization survey is an ultradeep continuum imaging study of the COSMOS field conducted using the Karl G. Jansky Very Large Array. We obtained 1000 hr of L -band ( λ  = 20 cm) observations across four spectral windows (SPWs; 1.063–1.831 GHz) in a single pointing and produced a confusion-limited image with an apparent rms noise of 1.67 μ Jy beam ^−1 with a synthesized beam of 5 $\mathop{.}…”
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Prediction of Resthenosis After Carotid Endarterectomy by the Method of Computer Simulation by A. N. Kazantsev, R. A. Vinogradov, Yu. N. Zakharov, V. G. Borisov, M. A. Chernyavsky, V. N. Kravchuk, D. V. Shmatov, K. P. Chernykh, A. A. Sorokin, G. Sh. Baghdavadze, S. V. Artyukhov, G. G. Khubulava

“…The result of computer calculations using specialized software (Sim Vascular, Python, Open Foam) is a mathematical model of blood flow in a vessel. It is an array of calculated data describing the speed and other characteristics of the flow at each point of the artery. …”
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