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Multicentre comparison of various microaxial pump devices as a bridge to durable assist device implantation
Published 2025-08-01“…Abstract Aims Patients with acute decompensated advanced heart failure requiring left ventricular assist device (LVAD) implantation often experience progressive cardiac function deterioration, negatively impacting surgical outcomes. …”
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ICOS-expressing CAR-T cells mediate durable eradication of triple-negative breast cancer and metastasis
Published 2024-11-01“…Importantly, manipulating the expression of ICOSL on TNBC cells through overexpression or KO significantly influenced the function of ICOS-B7H3-CAR-T cells. This suggests that the level of ICOSL expression on TNBC cells is critical for enhancing the potent antitumor effects of ICOS-B7H3-CAR-T cells.Conclusion Overall, our study highlights the potential clinical application of ICOS as a promising strategy for combating TNBC recurrence and metastasis.…”
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High-Entropy Sulfide Nanoarchitectures with Triple-Shelled Hollow Design for Durable Sodium–Ion Batteries
Published 2025-06-01Get full text
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Enhancing catalytic durability in alkaline oxygen evolution reaction through squaric acid anion intercalation
Published 2025-04-01“…Abstract The corrosive acidic interfacial microenvironment caused by rapid multi-step deprotonation of alkaline oxygen evolution reaction in industrial high current water electrolysis is one of the key problems limiting its stability. Some functional anions derived from electrocatalysis exhibit special functionalities in modulating the interface microenvironment, but this matter has not received adequate attention in academic discussions. …”
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Transforming civil engineering: The role of nanotechnology and AI in advancing material durability and structural health monitoring
Published 2025-12-01“…Results confirm substantial improvements in structural durability and functionality, highlighting the transformative impact of nanotechnologies in civil engineering.…”
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Influence of Encapsulation Size and Textile Integration Techniques on the Wash Durability of Textiles with Integrated Electronic Yarn
Published 2025-07-01“…A crucial factor when developing e-textiles is ensuring their robustness and functionality during everyday activities, particularly washing. …”
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Extended Durability of a Cloth-Covered Star-Edwards Caged Ball Prosthesis in Aortic Position
Published 2009-01-01“…Despite the long-term results that have been reported there are only a few cases reported that exceed 30 years of durability. Here in, we report a 53-year-old patient with a well-functioning 35-year-old aortic Starr-Edwards caged ball prosthesis.…”
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Research progress of novel multifunctional monomers for dentin adhesives
Published 2025-06-01“…Bonding technology has made tremendous progress over the past 50 years, but there are still some unresolved issues regarding the durability of the bonding interface. In order to improve the durability and stability of dentin bonding, researchers have been trying to develop adhesives with more biological functions, such as promoting dentin remineralisation, inhibiting enzyme activity at the bonding interface, and enhancing collagen cross-linking. …”
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The Management of Regional Biodiversity – Forest Potential
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Antigen-independent activation is critical for the durable antitumor effect of GUCY2C-targeted CAR-T cells
Published 2024-10-01“…The underlying mechanism was further investigated based on mutation of the hinge and transmembrane domains.Results We found that the composition of the antigen-sensitive scFv, CD8α hinge, CD8α transmembrane, and CD28 costimulatory domains boosted CAR-T cells to rapidly kill tumors, maintain high expansion capacity, and long-term efficacy in various colorectal cancer models. The durable antitumor function was attributed to the optimal CAR tonic signaling that conferred CAR-T cells with autonomous activation, proliferation, survival and cytokine release in the absence of antigen stimulation. …”
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Water-soluble fullerene derivatives as radical scavengers for highly durable proton exchange membrane fuel cells
Published 2025-07-01“…These findings highlight the potential of functionalized fullerenes and their derivatives as effective PEMFC additives, enhancing both performance and durability for wider hydrogen energy system adoption.…”
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Wearable Solutions: Design, Durability, and Electrical Performance of Snap Connectors and Integrating Them into Textiles Using Interconnects
Published 2024-07-01“…Factors such as electrical functionality and mechanical durability along with textile compatibility are crucial for their performance. …”
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A Novel Method of Self-Healing Concrete to Improve Durability and Extend the Service Life of Civil Infrastructure
Published 2023-01-01“…First, the model employs PSO-LSSVM to achieve highly accurate predictions of relative dynamic elastic modulus and chloride ion permeability coefficient, which are key indicators of the concrete durability. Subsequently, the predicted regression functions for concrete durability are utilized as fitness functions, and the improved NSGA-II algorithm is employed to obtain the optimal mix ratio for durable concrete. …”
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Improved durability of 3D-printed ear tags for virtual fencing in cattle: mechanical and field performance
Published 2025-08-01“…However, much of the research focuses on the technology and functionality of these systems, and less attention has been given to the materials used in their design, which are critical to their long-term effectiveness and durability. …”
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A safe insect-based chikungunya fever vaccine affords rapid and durable protection in cynomolgus macaques
Published 2024-12-01“…Transcriptome and functional analyses reveal that EILV/CHIKV triggered T cell, memory B cell and antibody responses in a dose-dependent manner. …”
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Dip-coating of nylon/chitosan/hydroxyapatite/TiO2 biocoatings to improve durability of metallic prostheses
Published 2025-06-01Get full text
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