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Scalable Manufacturing Method for Model Protein-Loaded PLGA Nanoparticles: Biocompatibility, Trafficking and Release Properties
Published 2025-01-01“…Importantly, cellular uptake studies revealed that the NPs were not internalized. Furthermore, encapsulated WGA-488 protein retained its functional activity after release, validating the integrity of the encapsulation and release processes. …”
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Effect of partial oocyte maturation before ovum pick up on developmental competence of buffalo oocytes
Published 2023-11-01“…The estrous cycle of buffalo was synchronized by double shot prostaglandin (PGF2α, Fatro, Ozzano Emilia, Italy) with 11-day intervals. …”
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CHARACTERISTIC CHANGES IN THE COPY NUMBER OF INTERSPERSED REPEATS IN BONE MARROW CELLS OF MICE TREATED WITH CYCLOPHOSPHAMIDE AND EXOGENOUS HUMAN DNA
Published 2014-12-01“…It was established that exogenous DNA reaches internal compartments of bone marrow cells (BMCs) where it is processed (Dolgova et al., 2012a). …”
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Late-time Optical and X-Ray Emission Evolution of the Oxygen-rich SN 1996cr
Published 2025-01-01“…Magellan IMACS optical spectra taken in 2017 July and 2021 August show a very different spectrum from that seen in 2006 with broad, double-peaked optical emission lines of oxygen, argon, and sulfur with expansion velocities of ±4500 km s ^−1 . …”
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Evaluation of a strategy for tumor-initiating stem cell eradication in primary human glioblastoma cultures as a model
Published 2018-11-01“…The key elements of the strategy were the following indicator results: (1) evaluation of the presence of tumor-initiating stem cells in a population of cells from analyzed cultures by their ability to internalize double-stranded labeled DNA (TAMRA+ cells); (2) determination of the reference time points of the repair cycle of DNA interstrand cross-links induced by cross-linking cytostatic mitomycin C; (3) evaluation of cell cycle synchronization; (4) determination of the time (day after therapy initiation) when TAMRA+ cells were synchronously present in phase G1/S of the cell cycle, sensitive to the therapy; and (5) establishment of the TAMRA+ (tumor-initiating stem cells) eradication schedule. …”
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Effects of intranasal oxytocin on neural reward processing in children and adolescents with reactive attachment disorder: A randomized controlled trial
Published 2023-01-01“…Under placebo conditions, the severity of internalizing problems in patients with RAD was negatively correlated with ventral striatal activity. …”
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670
Economic impact of heart failure with preserved ejection fraction: insights from the ALDO‐DHF trial
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A novel model-based meta-analysis to indirectly estimate the comparative efficacy of two medications: an example using DPP-4 inhibitors, sitagliptin and linagliptin, in treatment o...
Published 2013-03-01“…For the indirect comparison, a population of 1000 patients was simulated from the model with a racial composition reflecting the average racial distribution of the linagliptin trials, and baseline HbA1c of 8%.Results The model was developed using longitudinal data from 11 234 patients (10 linagliptin, 15 sitagliptin trials), and assessed by internal evaluation techniques, demonstrating that the model adequately described the observations. …”
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673
Call for Papers: How attractive are political parties and trade unions to young people?
Published 2018-06-01“…Its editorial board consists of about 50 internationally renowned experts from ten different countries. …”
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TRAF2 and RIPK1 redundantly mediate classical NFκB signaling by TNFR1 and CD95-type death receptors
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TALome and phenotypic analysis of Pakistani Xanthomonas oryzae pv. oryzae population revealed novel virulent TALEs contributing to bacterial blight of rice
Published 2025-01-01“…In contrast, paddy trails on NILs containing single, double, and triple mutants of OsSWEET11a, OsSWEET13, and OsSWEET14 in the effector binding elements (EBEs) of cv. …”
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Electrocardiographic signs of cardiac ischemia at rest and during exercise in patients with COPD traveling to 3,100 m: data from a randomized trial of acetazolamide
Published 2025-02-01“…Exercise electrocardiograms were recorded at the National Center of Internal Medicine and Cardiology, Bishkek (760 m) and on the day of arrival at the Tuja Ashu high-altitude clinic (3,100 m), Kyrgyzstan. …”
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Assessing the robustness and implications of econometric estimates of climate sensitivity
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